Propionibacterium freudenreichii subsp. freudenreichii DSM 20271: RM25_0205
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Entry
RM25_0205 CDS
T03860
Name
(GenBank) Pyruvate dehydrogenase E1 component, alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
pfre
Propionibacterium freudenreichii subsp. freudenreichii DSM 20271
Pathway
pfre00280
Valine, leucine and isoleucine degradation
pfre00640
Propanoate metabolism
pfre00785
Lipoic acid metabolism
pfre01100
Metabolic pathways
pfre01110
Biosynthesis of secondary metabolites
pfre01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
pfre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
RM25_0205
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
RM25_0205
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RM25_0205
Enzymes [BR:
pfre01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
RM25_0205
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AJQ89937
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Position
254071..255183
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AA seq
370 aa
AA seq
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MDSDDPTQPLQLLTPDGTLVDNPRFPWEGSDEDLVDMLRQMTTARRFDVEGAALQRHGEL
GLWAPLSGQEAYQAAVTQVMKPQDMVFGTYREQSIALQKGVPLGDILAVWRGSSLSRWIA
SDAQVAPYYMIIGAQPLHAVGYAMGVARDKAKHPTDPANDAVTLTIYGDGASSQGDVNEA
LVYAASQQAPVVFLNVNNQWAISEPSSVQTRIPLYQRAMGFGIPGIRVDGNDPLACHAVL
NWAFDEVRSGSGPVLVEAVTYRMGPHTTSDDPTKYRSSQVTEEWKAKDPIERLRSYLLER
GLIDYAWTEKLNADLDTFGALVRDTCRALPNTPMSEVFDAVTADPGLYLSEQRADCLDWL
ATPPSEGAAE
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atggattccgatgacccgacgcagcccctgcagctgctgacacctgacggcacgctcgtc
gacaatccacggttcccctgggagggcagcgacgaggatctcgtcgacatgctgcgccag
atgaccaccgcccgccgtttcgacgtcgagggcgcggccctgcagcgtcacggcgaactc
ggcctgtgggcgcccctgtcgggccaggaggcctaccaggccgccgtcacccaggtgatg
aagccccaggacatggtgttcggcacctaccgcgagcagtcgatcgccctgcagaagggc
gtgccgctgggtgacatcctggccgtgtggcgcgggtcgagcctgtctcgctggatcgcc
agcgacgcccaggtggcgccctattacatgatcatcggcgcccagccgctgcatgcggtg
ggctatgcgatgggagtggcccgcgacaaggccaagcaccccaccgacccggcgaacgat
gccgtgacgctgaccatctacggcgatggcgcgtccagccagggcgatgtgaacgaggcg
ctggtctatgccgcctcgcagcaggcgccggtcgtcttcctcaacgtgaacaaccagtgg
gccatcagcgagccgtccagcgtgcagacgcgcatcccgctctaccagcgggcgatgggc
ttcggcatccccggcatccgggtggacggaaacgacccgctggcctgccacgcggtgctc
aactgggccttcgacgaggtgcgctcgggttccgggccggtgctcgtggaagccgtcacc
tatcgcatgggcccccacaccaccagcgacgatcccaccaagtaccgctcgtcgcaggtc
accgaggagtggaaggccaaggacccgatcgagcgcctgcgcagttatctgctggagcgc
ggcctgatcgactatgcgtggaccgagaagctcaacgccgacctcgacaccttcggtgcg
ctggtgcgcgacacctgtcgggcgctgccgaacaccccgatgtcggaggtcttcgacgcc
gtcaccgcggatccgggtctctatctgagcgagcagcgggccgactgcctcgactggctc
gccaccccgcccagcgaaggagcagcagaatga
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