Pongo abelii (Sumatran orangutan): 100171532
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Entry
100171532 CDS
T01416
Gene name
MDM2
Definition
(RefSeq) E3 ubiquitin-protein ligase Mdm2
KO
K06643
E3 ubiquitin-protein ligase Mdm2 [EC:
2.3.2.27
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01522
Endocrine resistance
pon01524
Platinum drug resistance
pon04068
FoxO signaling pathway
pon04110
Cell cycle
pon04115
p53 signaling pathway
pon04120
Ubiquitin mediated proteolysis
pon04144
Endocytosis
pon04151
PI3K-Akt signaling pathway
pon04218
Cellular senescence
pon04625
C-type lectin receptor signaling pathway
pon04919
Thyroid hormone signaling pathway
pon05163
Human cytomegalovirus infection
pon05165
Human papillomavirus infection
pon05169
Epstein-Barr virus infection
pon05200
Pathways in cancer
pon05202
Transcriptional misregulation in cancer
pon05203
Viral carcinogenesis
pon05205
Proteoglycans in cancer
pon05206
MicroRNAs in cancer
pon05214
Glioma
pon05215
Prostate cancer
pon05218
Melanoma
pon05219
Bladder cancer
pon05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100171532 (MDM2)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100171532 (MDM2)
04151 PI3K-Akt signaling pathway
100171532 (MDM2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100171532 (MDM2)
09143 Cell growth and death
04110 Cell cycle
100171532 (MDM2)
04115 p53 signaling pathway
100171532 (MDM2)
04218 Cellular senescence
100171532 (MDM2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
100171532 (MDM2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100171532 (MDM2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100171532 (MDM2)
05202 Transcriptional misregulation in cancer
100171532 (MDM2)
05206 MicroRNAs in cancer
100171532 (MDM2)
05205 Proteoglycans in cancer
100171532 (MDM2)
05203 Viral carcinogenesis
100171532 (MDM2)
09162 Cancer: specific types
05214 Glioma
100171532 (MDM2)
05220 Chronic myeloid leukemia
100171532 (MDM2)
05218 Melanoma
100171532 (MDM2)
05219 Bladder cancer
100171532 (MDM2)
05215 Prostate cancer
100171532 (MDM2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100171532 (MDM2)
05169 Epstein-Barr virus infection
100171532 (MDM2)
05165 Human papillomavirus infection
100171532 (MDM2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100171532 (MDM2)
01522 Endocrine resistance
100171532 (MDM2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pon04131
]
100171532 (MDM2)
04121 Ubiquitin system [BR:
pon04121
]
100171532 (MDM2)
Enzymes [BR:
pon01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100171532 (MDM2)
Membrane trafficking [BR:
pon04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100171532 (MDM2)
Ubiquitin system [BR:
pon04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
MDM2/MDM4 proteins
100171532 (MDM2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-C3HC4_3
SWIB
zf-RanBP
zf-RING_2
zf-FPG_IleRS
Motif
Other DBs
NCBI-GeneID:
100171532
NCBI-ProteinID:
NP_001124685
Ensembl:
ENSPPYG00000004754
UniProt:
Q5RF93
LinkDB
All DBs
Position
12
AA seq
497 aa
AA seq
DB search
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
SSDSGTSVSENRCHLEGGRDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD
WLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEGD
PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE
EGFDVPDCKKTIVNDSKESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEF
EREETQDKEESMESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP
CPVCRQPIQMIVLTYFP
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atggtgaggagcaggcaaatgtgcaataccaacatgtctgtacctactgatggtgctgta
accacctcacagattccagcttcggaacaagagaccctggttagaccaaagccattgctt
ttgaagttattaaagtctgttggtgcacaaaaagacacttatactatgaaagaggttctt
ttttatcttggccagtatattatgactaaacgattatatgatgagaagcaacaacatatt
gtatattgttcaaatgatcttctaggagatttgtttggcgtgccaagcttctctgtgaaa
gagcacaggaaaatatataccatgatctacagaaacttggtagtagtcaatcagcaggaa
tcatcagactcaggtacatctgtgagtgagaacaggtgtcaccttgaaggtgggcgtgat
caaaaggaccttgtgcaagagcttcaggaagagaaaccttcatcttcacatttggtttct
agaccatctacctcatccagaaggagagcaattagtgagacagaagaaaattcagatgaa
ttatctggtgaacgacaaagaaaacgccacaaatctgatagtatttccctttcctttgat
gaaagcctggctctgtgtgtaataagggagatatgttgtgaaagaagcagtagcagtgaa
tctacagggacgccatcgaatccggatcttgatgctggtgtaagtgaacattcaggtgat
tggttggatcaggattcagtttcagatcagtttagtgtagaatttgaagttgaatctctc
gactcagaagattatagccttagtgaagaaggacaagaactctcagatgaagatgatgag
gtatatcgagttactgtgtatcaggcaggggagagtgatacagattcatttgaaggagat
cctgaaatttccctagctgactattggaaatgcacttcatgcaatgaaatgaatcccccc
cttccatcacattgcaacagatgttgggcccttcgtgagaattggcttcctgaagataaa
gggaaagataaaggggaaatctctgagaaagccaaactggaaaactcaacacaagctgaa
gagggctttgatgttcctgattgtaaaaaaactatagtgaatgattccaaagagtcatgt
gttgaggaaaatgatgataaaattacacaagcttcacagtcacaagaaagtgaggactat
tctcagccatcaacttctagtagcattatttatagcagccaagaagatgtgaaagagttt
gaaagggaagaaacccaagacaaagaagagagtatggaatccagtttgccccttaatgcc
attgaaccttgtgtgatttgtcaaggtcgacctaaaaatggttgcattgtccatggcaaa
acaggacatcttatggcctgctttacttgtgcaaagaagctaaagaaaaggaataagccc
tgcccagtatgtagacaaccaattcaaatgattgtgctaacttatttcccctag
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