KEGG   Pongo abelii (Sumatran orangutan): 100171541
Entry
100171541         CDS       T01416                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon04062  Chemokine signaling pathway
pon04066  HIF-1 signaling pathway
pon04068  FoxO signaling pathway
pon04217  Necroptosis
pon04550  Signaling pathways regulating pluripotency of stem cells
pon04630  JAK-STAT signaling pathway
pon04659  Th17 cell differentiation
pon04917  Prolactin signaling pathway
pon04920  Adipocytokine signaling pathway
pon04931  Insulin resistance
pon04933  AGE-RAGE signaling pathway in diabetic complications
pon04935  Growth hormone synthesis, secretion and action
pon05145  Toxoplasmosis
pon05160  Hepatitis C
pon05161  Hepatitis B
pon05162  Measles
pon05163  Human cytomegalovirus infection
pon05167  Kaposi sarcoma-associated herpesvirus infection
pon05169  Epstein-Barr virus infection
pon05200  Pathways in cancer
pon05203  Viral carcinogenesis
pon05205  Proteoglycans in cancer
pon05206  MicroRNAs in cancer
pon05212  Pancreatic cancer
pon05221  Acute myeloid leukemia
pon05223  Non-small cell lung cancer
pon05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pon05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100171541 (STAT3)
   04066 HIF-1 signaling pathway
    100171541 (STAT3)
   04068 FoxO signaling pathway
    100171541 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100171541 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100171541 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100171541 (STAT3)
   04062 Chemokine signaling pathway
    100171541 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100171541 (STAT3)
   04917 Prolactin signaling pathway
    100171541 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    100171541 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100171541 (STAT3)
   05206 MicroRNAs in cancer
    100171541 (STAT3)
   05205 Proteoglycans in cancer
    100171541 (STAT3)
   05203 Viral carcinogenesis
    100171541 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100171541 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100171541 (STAT3)
   05221 Acute myeloid leukemia
    100171541 (STAT3)
   05223 Non-small cell lung cancer
    100171541 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100171541 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100171541 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100171541 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    100171541 (STAT3)
   05161 Hepatitis B
    100171541 (STAT3)
   05160 Hepatitis C
    100171541 (STAT3)
   05163 Human cytomegalovirus infection
    100171541 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100171541 (STAT3)
   05169 Epstein-Barr virus infection
    100171541 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100171541 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100171541 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100171541 (STAT3)
Transcription factors [BR:pon03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100171541 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135
Other DBs
NCBI-GeneID: 100171541
NCBI-ProteinID: NP_001124694
Ensembl: ENSPPYG00000008392
UniProt: Q5RF79
LinkDB
Position
17
AA seq 722 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCPWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMPEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPEEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPFIDAV
WK
NT seq 2169 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagcttgacacacggtacctggagcagctccatcag
ctctacagtgacagcttcccaatggagctgcggcagtttctggccccttggattgagagt
caagattgggcgtatgcggccagcaaagaatcacatgccactttggtgtttcataatctc
ctgggagagattgaccagcagtatagccgcttcctgcaagagtcgaatgttctctatcag
cacaatctacgaagaatcaagcagtttcttcagagcaggtatcttgagaagccaatggag
attgcccggattgtggcccggtgcccgtgggaagaatcacgcctcctacagactgcagcc
actgcggcccagcaagggggccaggccaaccaccccacagcagccgtggtgacggagaag
cagcagatgccggagcagcaccttcaggatgtccggaagagagtgcaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaagatctgaatggaaacaaccagtcggtgaccaggcagaagatg
cagcagctggaacagatgctcactgcgctggaccagatgcggagaagcatcgtgagtgag
ctggcggggcttttgtcagcgatggagtacgtgcagaaaactctcacggacgaggagctg
gctgactggaagaggcgacaacagattgcctgcattggaggcccgcccaacatctgccta
gatcggctagaaaactggataacgtcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcaaaaagtttcctacaaaggggaccccattgtacag
caccggccgatgctggaggagagaatcgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggtagagcggcagccctgcatgcccatgcatcctgaccggcccctcgtcatcaag
accggcgtccagttcaccactaaagtcaggttgctggtcaaattccctgagttgaattat
cagcttaaaattaaagtgtgcattgacaaagactctggggatgttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagaatccaac
aacggcagcctctctgcagaattcaaacacttgaccctgagggagcagagatgtgggaat
gggggccgagccaattgtgatgcttccctgattgtgactgaggagctgcacctgatcacc
tttgagaccgaggtatatcaccaaggcctcaagattgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcgtccatcctgtggtac
aacatgctgaccaacaatcccaagaacgtaaacttttttaccaagcccccaattggaacc
tgggatcaagtggccgaggtcctgagctggcaattctcctccaccaccaagcgaggactg
agcatcgagcagctgactacactggcagagaaactcttgggacctggtgtgaattattca
gggtgtcagatcacatgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaatatcattgaccttgtgaaaaagtacatcctggccctttgg
aacgaagggtacatcatgggctttatcagtaaggagcgggagcgggccatcttgagcact
aagcctccaggcaccttcctgctaagattcagtgaaagcagcaaagaaggcggcgtcact
ttcacttgggtggagaaggacatcagcggtaagacccagatccagtccgtggaaccatac
accaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gatgctaccaatatcctggtgtctccactggtctatctctaccctgacattcccgaggag
gaggcattcggaaagtattgtcggccagagagccaggagcatcctgaagctgacccaggt
agcgctgccccatacctgaagaccaagtttatctgtgtgacaccattcattgatgcagtt
tggaaataa

DBGET integrated database retrieval system