KEGG   Pongo abelii (Sumatran orangutan): 100171541
Entry
100171541         CDS       T01416                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon04062  Chemokine signaling pathway
pon04066  HIF-1 signaling pathway
pon04068  FoxO signaling pathway
pon04217  Necroptosis
pon04550  Signaling pathways regulating pluripotency of stem cells
pon04630  JAK-STAT signaling pathway
pon04659  Th17 cell differentiation
pon04917  Prolactin signaling pathway
pon04920  Adipocytokine signaling pathway
pon04931  Insulin resistance
pon04933  AGE-RAGE signaling pathway in diabetic complications
pon04935  Growth hormone synthesis, secretion and action
pon05145  Toxoplasmosis
pon05160  Hepatitis C
pon05161  Hepatitis B
pon05162  Measles
pon05163  Human cytomegalovirus infection
pon05167  Kaposi sarcoma-associated herpesvirus infection
pon05169  Epstein-Barr virus infection
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
pon05203  Viral carcinogenesis
pon05205  Proteoglycans in cancer
pon05206  MicroRNAs in cancer
pon05212  Pancreatic cancer
pon05221  Acute myeloid leukemia
pon05223  Non-small cell lung cancer
pon05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pon05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100171541 (STAT3)
   04066 HIF-1 signaling pathway
    100171541 (STAT3)
   04068 FoxO signaling pathway
    100171541 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100171541 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100171541 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100171541 (STAT3)
   04062 Chemokine signaling pathway
    100171541 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100171541 (STAT3)
   04917 Prolactin signaling pathway
    100171541 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    100171541 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100171541 (STAT3)
   05206 MicroRNAs in cancer
    100171541 (STAT3)
   05205 Proteoglycans in cancer
    100171541 (STAT3)
   05203 Viral carcinogenesis
    100171541 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100171541 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100171541 (STAT3)
   05221 Acute myeloid leukemia
    100171541 (STAT3)
   05223 Non-small cell lung cancer
    100171541 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100171541 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100171541 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100171541 (STAT3)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100171541 (STAT3)
   05160 Hepatitis C
    100171541 (STAT3)
   05171 Coronavirus disease - COVID-19
    100171541 (STAT3)
   05162 Measles
    100171541 (STAT3)
   05163 Human cytomegalovirus infection
    100171541 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100171541 (STAT3)
   05169 Epstein-Barr virus infection
    100171541 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100171541 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100171541 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100171541 (STAT3)
Transcription factors [BR:pon03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100171541 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135
Other DBs
NCBI-GeneID: 100171541
NCBI-ProteinID: NP_001124694
Ensembl: ENSPPYG00000008392
UniProt: Q5RF79
LinkDB
Position
17
AA seq 722 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCPWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMPEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPEEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPFIDAV
WK
NT seq 2169 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagcttgacacacggtacctggagcagctccatcag
ctctacagtgacagcttcccaatggagctgcggcagtttctggccccttggattgagagt
caagattgggcgtatgcggccagcaaagaatcacatgccactttggtgtttcataatctc
ctgggagagattgaccagcagtatagccgcttcctgcaagagtcgaatgttctctatcag
cacaatctacgaagaatcaagcagtttcttcagagcaggtatcttgagaagccaatggag
attgcccggattgtggcccggtgcccgtgggaagaatcacgcctcctacagactgcagcc
actgcggcccagcaagggggccaggccaaccaccccacagcagccgtggtgacggagaag
cagcagatgccggagcagcaccttcaggatgtccggaagagagtgcaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaagatctgaatggaaacaaccagtcggtgaccaggcagaagatg
cagcagctggaacagatgctcactgcgctggaccagatgcggagaagcatcgtgagtgag
ctggcggggcttttgtcagcgatggagtacgtgcagaaaactctcacggacgaggagctg
gctgactggaagaggcgacaacagattgcctgcattggaggcccgcccaacatctgccta
gatcggctagaaaactggataacgtcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcaaaaagtttcctacaaaggggaccccattgtacag
caccggccgatgctggaggagagaatcgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggtagagcggcagccctgcatgcccatgcatcctgaccggcccctcgtcatcaag
accggcgtccagttcaccactaaagtcaggttgctggtcaaattccctgagttgaattat
cagcttaaaattaaagtgtgcattgacaaagactctggggatgttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagaatccaac
aacggcagcctctctgcagaattcaaacacttgaccctgagggagcagagatgtgggaat
gggggccgagccaattgtgatgcttccctgattgtgactgaggagctgcacctgatcacc
tttgagaccgaggtatatcaccaaggcctcaagattgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcgtccatcctgtggtac
aacatgctgaccaacaatcccaagaacgtaaacttttttaccaagcccccaattggaacc
tgggatcaagtggccgaggtcctgagctggcaattctcctccaccaccaagcgaggactg
agcatcgagcagctgactacactggcagagaaactcttgggacctggtgtgaattattca
gggtgtcagatcacatgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaatatcattgaccttgtgaaaaagtacatcctggccctttgg
aacgaagggtacatcatgggctttatcagtaaggagcgggagcgggccatcttgagcact
aagcctccaggcaccttcctgctaagattcagtgaaagcagcaaagaaggcggcgtcact
ttcacttgggtggagaaggacatcagcggtaagacccagatccagtccgtggaaccatac
accaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gatgctaccaatatcctggtgtctccactggtctatctctaccctgacattcccgaggag
gaggcattcggaaagtattgtcggccagagagccaggagcatcctgaagctgacccaggt
agcgctgccccatacctgaagaccaagtttatctgtgtgacaccattcattgatgcagtt
tggaaataa

KEGG   Pongo abelii (Sumatran orangutan): 100173683
Entry
100173683         CDS       T01416                                 

Gene name
STAT1
Definition
(RefSeq) signal transducer and activator of transcription 1-alpha/beta
  KO
K11220  signal transducer and activator of transcription 1
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04062  Chemokine signaling pathway
pon04217  Necroptosis
pon04380  Osteoclast differentiation
pon04620  Toll-like receptor signaling pathway
pon04621  NOD-like receptor signaling pathway
pon04625  C-type lectin receptor signaling pathway
pon04630  JAK-STAT signaling pathway
pon04658  Th1 and Th2 cell differentiation
pon04659  Th17 cell differentiation
pon04917  Prolactin signaling pathway
pon04919  Thyroid hormone signaling pathway
pon04933  AGE-RAGE signaling pathway in diabetic complications
pon04935  Growth hormone synthesis, secretion and action
pon05140  Leishmaniasis
pon05145  Toxoplasmosis
pon05152  Tuberculosis
pon05160  Hepatitis C
pon05161  Hepatitis B
pon05162  Measles
pon05164  Influenza A
pon05165  Human papillomavirus infection
pon05167  Kaposi sarcoma-associated herpesvirus infection
pon05168  Herpes simplex virus 1 infection
pon05169  Epstein-Barr virus infection
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
pon05212  Pancreatic cancer
pon05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pon05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100173683 (STAT1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100173683 (STAT1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100173683 (STAT1)
   04621 NOD-like receptor signaling pathway
    100173683 (STAT1)
   04625 C-type lectin receptor signaling pathway
    100173683 (STAT1)
   04658 Th1 and Th2 cell differentiation
    100173683 (STAT1)
   04659 Th17 cell differentiation
    100173683 (STAT1)
   04062 Chemokine signaling pathway
    100173683 (STAT1)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    100173683 (STAT1)
   04935 Growth hormone synthesis, secretion and action
    100173683 (STAT1)
   04919 Thyroid hormone signaling pathway
    100173683 (STAT1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100173683 (STAT1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100173683 (STAT1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100173683 (STAT1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100173683 (STAT1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100173683 (STAT1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100173683 (STAT1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100173683 (STAT1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100173683 (STAT1)
   05160 Hepatitis C
    100173683 (STAT1)
   05171 Coronavirus disease - COVID-19
    100173683 (STAT1)
   05164 Influenza A
    100173683 (STAT1)
   05162 Measles
    100173683 (STAT1)
   05168 Herpes simplex virus 1 infection
    100173683 (STAT1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100173683 (STAT1)
   05169 Epstein-Barr virus infection
    100173683 (STAT1)
   05165 Human papillomavirus infection
    100173683 (STAT1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100173683 (STAT1)
   05140 Leishmaniasis
    100173683 (STAT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100173683 (STAT1)
Transcription factors [BR:pon03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100173683 (STAT1)
SSDB
Motif
Pfam: STAT_alpha STAT_int STAT_bind STAT1_TAZ2bind SH2 TRPM_tetra BLI1
Other DBs
NCBI-GeneID: 100173683
NCBI-ProteinID: NP_001126683
Ensembl: ENSPPYG00000013027
UniProt: Q5R5U0
LinkDB
Position
2B
AA seq 750 aa
MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDL
LSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQ
RFNQAQSGNIQSTVMLDKQRELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNR
EHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWK
RRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQV
LWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKV
KVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTN
EGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAE
PRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWT
RFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFL
LRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIP
ENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTT
DNLLPMSPEEFDEVSRIVGSVEFDSMMNTV
NT seq 2253 nt   +upstreamnt  +downstreamnt
atgtctcagtggtacgaacttcagcagcttgactcaaaattcctggagcaggttcaccag
ctttatgatgacagttttcccatggaaatcagacaatacctggcacagtggttagaaaag
caagactgggagcacgctgccaatgatgtttcatttgccaccatccgttttcatgacctc
ctatcacagctggatgatcaatatagtcgcttttctttggagaataacttcttgctacag
cataacataaggaaaagcaagcgtaatcttcaggataattttcaggaagacccaatccag
atgtctatgatcatttacagctgtctgaaggaagaaaggaaaattctggaaaacgcccag
agatttaatcaggctcagtcggggaatattcagagcacagtgatgttagacaaacagaga
gagcttgacagtaaagtcagaaatgtgaaggacaaggttatgtgtatagagcatgaaatc
aagagcctggaagatttacaagatgaatatgacttcaaatgcaaaaccttgcagaacaga
gaacacgagaccaatggtgtggcaaagagtgatcagaaacaagaacagctgttactcaag
aagatgtatttaatgcttgacaataagagaaaggaagtagttcacaaaataatagagttg
ctgaatgtcactgaacttacccagaatgccctcattaatgatgaactagtggagtggaag
cggagacagcagagcgcctgtattggggggccgcccaatgcttgcctggatcagctgcag
aactggttcactatagttgcggagagtctgcagcaagttcggcagcagcttaaaaagctg
gaggaattggaacagaaatacacctacgaacatgaccctatcacaaaaaacaaacaagtg
ttatgggaccgcaccttcagtcttttccagcagctcattcagagctcgtttgtggtggaa
agacagccctgcatgccaacgcaccctcagaggccgctggtcttgaagacaggggtccag
ttcactgtgaagttgagactgttggtgaaattgcaagagctgaattataatttgaaagtc
aaagtcttatttgataaagatgtgaatgagagaaatacagtaaaaggatttaggaagttc
aacatcttgggcacacacacaaaagtgatgaacatggaggagtccaccaatggcagtctg
gcggctgaatttcggcacctgcaattgaaagaacagaaaaatgctggcaccagaacgaat
gagggtcctctcattgttactgaagagcttcactcccttagttttgaaacccaattgtgc
cagcctggtttggtaattgacctcgagacgacctctctgcctgttgtggtgatctccaac
gtcagccagctcccaagcggttgggcctccatcctttggtacaacatgctggtggcggaa
cccaggaatctgtccttcttcctgactccaccatgtgcacgatgggctcagctttcagaa
gtgctgagttggcagttttcttctgtcaccaaaagaggtctcaatgtggaccagctgaac
atgttgggagagaagcttcttggtcctaacgccagccccgatggcctcattccgtggacg
aggttttgtaaggagaatataaatgataaaaattttcccttctggctttggattgaaagc
atcctagaactcattaaaaaacacctcctccctctctggaatgatgggtgcatcatgggc
ttcatcagcaaggagcgagagcgtgccctgttgaaggaccagcagccggggaccttcctg
ctgcggttcagcgagagctcccgggaaggggccatcacattcacatgggtggagcggtcc
cagaatggaggcgaacctgacttccatgcggttgaaccctacacgaagaaagaactttct
gctgttactttccctgacatcattcgcaattataaagtcatggctgctgagaatattcct
gagaatcccctgaagtatctgtatccaaatattgacaaagaccatgcctttggaaagtat
tactccaggccaaaggaagcaccagagccaatggaacttgatggccctaaaggaactgga
tatatcaagactgaattgatttctgtgtctgaagttcacccttctagacttcagaccaca
gacaacctgctccccatgtctcctgaggagtttgacgaggtgtctcggatagtgggctct
gtagaattcgacagtatgatgaacacagtatag

KEGG   Pongo abelii (Sumatran orangutan): 100173709
Entry
100173709         CDS       T01416                                 

Gene name
STAT6
Definition
(RefSeq) signal transducer and activator of transcription 6
  KO
K11225  signal transducer and activator of transcription 6
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04217  Necroptosis
pon04630  JAK-STAT signaling pathway
pon04658  Th1 and Th2 cell differentiation
pon04659  Th17 cell differentiation
pon05161  Hepatitis B
pon05200  Pathways in cancer
pon05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100173709 (STAT6)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100173709 (STAT6)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100173709 (STAT6)
   04659 Th17 cell differentiation
    100173709 (STAT6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100173709 (STAT6)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100173709 (STAT6)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100173709 (STAT6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100173709 (STAT6)
Transcription factors [BR:pon03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100173709 (STAT6)
SSDB
Motif
Pfam: STAT6_C STAT_bind STAT_int STAT_alpha SH2 HisKA_2
Other DBs
NCBI-GeneID: 100173709
NCBI-ProteinID: NP_001126709
Ensembl: ENSPPYG00000004680
UniProt: Q5R5Q8
LinkDB
Position
12
AA seq 847 aa
MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
VQRLQASAGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKVVMEQFRHLPMP
FHWKQEELKFKTALRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
EVGAAGGELEPKTRALLIGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
FLGAPAKPPLVRADMVTEKQARELSVPQRPGAGAESTGEIINNTVPLENSIPGNCCSALF
KNLLLKKIKRCERKGTESVTEEKRAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
LQMPTMVPSHDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
LRANPSW
NT seq 2544 nt   +upstreamnt  +downstreamnt
atgtctctgtggggtctggtctccaagatgcccccagaaaaagtgcagcggctctatgtc
gactttccccaacacctgcggcatcttctgggtgactggctggagagccagccctgggag
ttcctggtcggctccgacgccttctgctgcaacttggctagtgccctactttcagacact
gtccagcgccttcaggcctcggcgggagagcagggggaggggagcaccatcttgcaacac
atcagcacccttgagagcatatatcagagggaccccctgaagctggtggccactttcaga
caaatacttcaaggagagaaaaaagttgttatggaacagttccgccacttgccaatgcct
ttccactggaagcaggaagaactcaagtttaagacagccctgcggaggctgcagcaccga
gtaggggagatccaccttctccgagaagccctgcagaagggggctgaggctggccaagtg
tctctgcacagcttgatagaaactcctgctaatgggactgggccaagtgaggccctggcc
atgctactgcaggagaccactggagagctagaggcagccaaagccctagtgctgaagagg
atccagatttggaaacggcagcagcagctggcagggaatggcgcaccctttgaggagagc
ctggccccactccaggagaggtgtgagagcctggtggacatttattcccagctacagcag
gaggtaggggcggctggcggggagcttgagcccaagacccgggcattgctgattggccgg
ctggatgaagtcctgcgaaccctcgtcaccagttgcttcctggtggagaagcagcccccc
caggtactgaagactcagaccaagttccaggctggagttcgattcctgttgggcttgagg
ttcctgggggccccagccaagcctccgctggtcagggctgacatggtgaccgagaagcag
gcgagggagctgagtgtgcctcagcgtcctggggctggagcagaaagcactggagaaatc
atcaacaacactgtgcccttggagaacagcattcctggtaactgctgctctgccctgttc
aagaacctgcttctcaagaagatcaagcggtgtgagcggaagggcactgagtctgtcaca
gaggagaagcgtgctgtgctcttctctgccagcttcacacttggccccggcaaactcccc
atccagctccaggccctgtctctgcccctggtggtcatcgtccatggcaaccaagacaac
aatgccaaagccaccatcctgtgggacaatgccttctctgagatggaccgcgtgcccttt
gtggtggctgagcgggtgccctgggaaaagatgtgtgaaactctgaacctgaagttcatg
gctgaggtggggaccaaccgggggctgctcccagagcacttcctcttcctggcccagaag
atcttcaatgacaacagcctcagcatggaggccttccagcaccgttctgtgtcctggtcg
cagttcaacaaggagatcctgctgggccgtggcttcaccttttggcagtggtttgatggt
gtcctggacctcaccaaacgctgtctccggagctactggtctgaccggctgatcattggc
ttcatcagcaaacagtacgttactagccttcttctcaatgagcccgacggaacctttctc
ctccgcttcagcgactcagagattgggggcatcaccattgcccatgtcatccggggccag
gacggctctccacagatagagaacatccagccattctctgccaaagacctgtccattcgc
tcactgggggaccgaatccgggatcttgctcagctcaaaaacctctatcccaagaagccc
aaggatgaggctttccggagccactacaagcctgaacagatgggtaaggatggcaggggt
tatgtcccagctaccatcaagatgaccgtggaaagggaccaaccacttcctaccccagag
ctccagatgcctaccatggtgccttctcatgaccttggaatggcccctgattcctccatg
agcatgcagcttggcccagatatggtgccccaggtgtacccaccacactctcactccatc
cccccgtatcaaggcctctccccagaagaatcagtcaacgtgttgtcagccttccaggag
cctcacctgcagatgccccccagcctgggccagatgagcctgccctttgaccagcctcac
ccccagggcctgctgccgtgccagcctcaggagcatgctgtgtccagccctgaccccctg
ctctgctcagatgtgaccatggtggaagacagctgcctgagccagccagtgacagcgttt
cctcagggcacttggattggtgaagacatattccctcctctgctgcctcccactgaacag
gacctcactaagcttctcctggaggggcaaggggagtcagggggagggtccttgggggcc
cagcccctcctgcagccctcccactatgggcaatctgggatctcaatgtcccacatggac
ctaagggccaaccccagttggtga

KEGG   Pongo abelii (Sumatran orangutan): 100436344
Entry
100436344         CDS       T01416                                 

Gene name
STAT4
Definition
(RefSeq) signal transducer and activator of transcription 4
  KO
K11222  signal transducer and activator of transcription 4
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04217  Necroptosis
pon04630  JAK-STAT signaling pathway
pon04658  Th1 and Th2 cell differentiation
pon05161  Hepatitis B
pon05200  Pathways in cancer
pon05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100436344 (STAT4)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100436344 (STAT4)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100436344 (STAT4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100436344 (STAT4)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100436344 (STAT4)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100436344 (STAT4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100436344 (STAT4)
Transcription factors [BR:pon03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100436344 (STAT4)
SSDB
Motif
Pfam: STAT_alpha STAT_int STAT_bind SH2 CRC_subunit NPV_P10
Other DBs
NCBI-GeneID: 100436344
NCBI-ProteinID: XP_024099172
Ensembl: ENSPPYG00000013028
LinkDB
Position
2B
AA seq 784 aa
MISAHCNLRLPGSSDPLASASQVAGITGACYRAWLIMSQWNQVQQLEIKFLEQVDQFYDD
NFPMEIRHLLAQWIENQDWEAASNNETMATILLQNLLIQLDEQLGRVSKEKNLLLIHNLK
RIRKVLQGKFHGNPMHVAVVISNCLREERRILAAANMPVQGPLEKSLQSSSVSERQRNVE
HKVAAIKNSVQMTEQDTKYLEDLQDEFDYRYKTIQTMDQSDKNSAMVNQEVLTLQEMLNS
LDFKRKEALSKMTQIIHETDLLMNNMLIEELQDWKQRQQIACIGGPLHNGLDQLQNCFTL
LAESLFQLRRQLEKLEEQSTKMTYEGDPIPMQRTHMLERVTFLIYNLFKNSFVVERQPCM
PTHPQRPLVLKTLIQFTVKLRLLIKLPELNYQVKVKASIDKNVSTLSNRRFVLCGTNVKA
MSIEESSNGSLSVEFRHLQPKEMKSSAGGKGNEGCHMVTEELHSITFETQICLYGLTIDL
ETSSLPVVMISNVSQLPNAWASIIWYNVSTNDSQNLVFFNNPPPATLSQLLEVMSWQFSS
YVGRGLNSDQLNMLAEKLTVQSSYSDGHLTWAKFCKEHLPGKSFTFWTWLEAILDLIKKH
ILPLWIDGYVMGFVSKEKERLLLKDKMPGTFLLRFSESHLGGITFTWVDHSESGEVRFHS
VEPYNKGRLSALPFADILRDYKVIMAENIPENPLKYLYPDIPKDKAFGKHYSSQPCEVSR
PTERGDKGYVPSVFIPISTIRSDSTEPHSPSDLLPMSPSVYAVLRENLSPTTIETAMKSP
YSAE
NT seq 2355 nt   +upstreamnt  +downstreamnt
atgatctcggctcactgcaacctccgcctccctggttcaagcgatcctcttgcctcagcc
tcccaagtagctgggattacaggtgcctgctaccgtgcctggctaatcatgtctcagtgg
aatcaagtccaacagttagaaatcaagtttttggagcaggtggatcaattctatgatgac
aactttcccatggaaattcggcatctgttggcccagtggattgaaaatcaagactgggag
gcagcttctaacaatgaaaccatggcaacgattcttcttcaaaacttgttaatacaactg
gatgaacagttaggtcgtgtttccaaagagaaaaacctactcttgatacacaatctaaaa
agaattaggaaggtccttcagggaaaatttcatggaaatccaatgcatgtagctgtggtt
atttcaaactgtttaagggaagagaggagaatattggctgcagccaacatgcctgtccag
gggcctctagagaaatccttacaaagttcttcagtttcagaaagacagaggaatgtggag
cacaaagtggctgccattaaaaacagtgtgcagatgacagaacaagataccaaatactta
gaagacctgcaagatgaatttgactacaggtataaaacaattcagacaatggatcagagt
gacaagaatagtgccatggtgaatcaggaagttttgacactgcaggaaatgcttaacagc
ctcgatttcaagagaaaggaggctctcagtaaaatgacccaaatcatccatgagacagac
ctgttaatgaacaacatgctcatagaagagctgcaagactggaagcagcggcagcaaatc
gcctgcatcgggggtccactccacaatgggctcgaccagcttcagaactgctttacacta
ttggcagaaagtcttttccaactcagaaggcaactggagaaactagaggagcaatctacc
aaaatgacatatgaaggtgatcccattccaatgcaaagaactcacatgctagaaagagtc
accttcttgatctacaatcttttcaagaactcatttgtggttgagcgacagccatgtatg
ccaacccaccctcagaggccgttggtacttaaaaccctaattcagttcactgtaaaactg
aggctactaataaaattgccagaactaaactatcaggtaaaggttaaagcatcaattgac
aagaatgtttcaactctaagcaaccgaagatttgtactttgtggaactaatgtcaaagcc
atgtctattgaagaatcttccaatgggagtctctcagtagaatttcgacatttgcaacca
aaggaaatgaagtccagtgctggaggtaaaggaaatgagggctgtcacatggtgactgaa
gaacttcattccataacctttgaaacacagatctgcctctatggcctgaccatagatttg
gagaccagctcattgcctgtggtgatgatttccaatgtcagtcagttacctaatgcttgg
gcatccatcatttggtacaacgtgtcaaccaatgattcccagaacttggttttctttaat
aatcctccacctgccacattgagtcaactactggaggtgatgagctggcagttttcatcg
tacgttggtcgtggccttaattcagatcaactcaatatgctggcagagaagcttacagtc
caatctagctacagtgatggtcacctcacctgggccaagttctgcaaggaacatttacct
ggtaaatcatttaccttctggacatggcttgaagcaatattggatctaattaagaaacac
attcttcccctttggattgatgggtatgtcatgggctttgttagcaaagagaaggaacgg
ctcttgctaaaggataaaatgcctggcacctttttattaagattcagtgaaagccatctt
ggaggaataactttcacctgggtggaccattctgaaagtggggaagtgagattccactct
gtagaaccctacaataaaggccggttgtctgctctgccattcgctgacatcctgcgagac
tacaaagttattatggctgaaaacattcctgaaaaccctctgaagtacctatatcctgac
attcccaaagacaaagccttcggtaaacactacagctctcagccttgtgaagtttcaaga
ccaacagaaaggggtgacaaaggttatgttccttccgtttttatccccatctcaacaatt
cgaagtgattcaacggagccacattctccatcagaccttcttcccatgtctccaagtgtg
tatgcggtgctgagagaaaacctgagtcccacaacaattgaaactgcaatgaagtctcct
tattctgctgaatga

KEGG   Pongo abelii (Sumatran orangutan): 100452011
Entry
100452011         CDS       T01416                                 

Gene name
STAT2
Definition
(RefSeq) signal transducer and activator of transcription 2 isoform X3
  KO
K11221  signal transducer and activator of transcription 2
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04062  Chemokine signaling pathway
pon04217  Necroptosis
pon04380  Osteoclast differentiation
pon04621  NOD-like receptor signaling pathway
pon04625  C-type lectin receptor signaling pathway
pon04630  JAK-STAT signaling pathway
pon05160  Hepatitis C
pon05161  Hepatitis B
pon05162  Measles
pon05164  Influenza A
pon05165  Human papillomavirus infection
pon05167  Kaposi sarcoma-associated herpesvirus infection
pon05168  Herpes simplex virus 1 infection
pon05169  Epstein-Barr virus infection
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100452011 (STAT2)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100452011 (STAT2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    100452011 (STAT2)
   04625 C-type lectin receptor signaling pathway
    100452011 (STAT2)
   04062 Chemokine signaling pathway
    100452011 (STAT2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100452011 (STAT2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100452011 (STAT2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100452011 (STAT2)
   05160 Hepatitis C
    100452011 (STAT2)
   05171 Coronavirus disease - COVID-19
    100452011 (STAT2)
   05164 Influenza A
    100452011 (STAT2)
   05162 Measles
    100452011 (STAT2)
   05168 Herpes simplex virus 1 infection
    100452011 (STAT2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100452011 (STAT2)
   05169 Epstein-Barr virus infection
    100452011 (STAT2)
   05165 Human papillomavirus infection
    100452011 (STAT2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100452011 (STAT2)
Transcription factors [BR:pon03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100452011 (STAT2)
SSDB
Motif
Pfam: STAT_alpha STAT2_C STAT_bind STAT_int SH2 CorA FAM184
Other DBs
NCBI-GeneID: 100452011
NCBI-ProteinID: XP_002823442
UniProt: A0A2J8UHQ1
LinkDB
Position
12
AA seq 851 aa
MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
QAQRAQSEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSVSQLKDQQDVFCFRYKIQ
AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTISGTFLL
RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDEVQQPLELKPEPELES
LELELGLAPEPELSQDLEQLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDRG
PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMLNGDPLLAGQNTVDEVYVSRPSHF
YTDGPLMPSEF
NT seq 2556 nt   +upstreamnt  +downstreamnt
atggcgcagtgggaaatgctgcagaatcttgacagcccctttcaggaccagctgcaccag
ctttactcacacagccttctgcctgtggacattcgacagtacttggctgtctggattgaa
gaccagaactggcaggaagctgcactcgggagtgatgattccaaggctaccatgctattc
ttccacttcttggatcagctgaactatgagtgtggccgttgcagccaggacccagagtcc
ttgttgctgcagcacaatttgcggaaattctgccgggacattcagcccttttcccaggat
cctacccagttggctgagatgatctttaacctccttctggaagaaaaaagaattttgatc
caggctcagagggcccaatcggagcaaggagagccagttctcgaaacacctgtggaaagc
cagcaacatgagattgaatcccggatcctggatttaagggctatgatggagaagctggta
aaatccgtcagtcaactgaaagaccagcaggatgtcttctgcttccgatataagatccag
gccaaagggaagacaccctctctggacccccatcagaccaaagagcagaagattctgcag
gaaactctcaatgaactggacaaaaggagaaaggaggtgctggatgcctccaaagcactg
ctaggccgattaacgaccctaatcgagctactgctgccaaagttggaggagtggaaggcc
cagcagcaaaaagcctgcatcagagctcccattgaccacgggttggaacagctggagaca
tggttcacagctggagcaaagctgttgtttcacctaaggcagctgctgaaggagctgaag
ggactgagttgcctggttagctatcaggatgaccctctgaccaaaggggtggacctacgc
aacgcccaggtcacagagttgctacagcgtctgctccacagagcctttgtggtagaaacc
cagccctgcatgccccaaactccccatcgacccctcatcctcaagactgggagcaagttc
accgtccgaacaaggctgctggtgagactccaggaaggcaatgagtcactgactgtggaa
gtctccattgacaggaatcctcctcaattacaaggcttccggaagttcaacattctgact
tcaaaccagaaaactttgacccccgagaaggggcagagtcagggtttgatttgggacttt
ggctacctgactctggtggagcaacgttcaggtggttcaggaaagggcagcaataagggg
ccactaggtgtgacagaggaactgcacatcatcagcttcacggtcaaatatacctaccag
ggtctgaagcaggagctgaaaacggacaccctccctgtggtgattatttccaacatgaac
cagctctcaattgcctgggcttcagttctctggttcaatttgctcagcccaaaccttcag
aaccagcagttcttctccaacccccccaaggccccctggagcttgctgggccctgctctc
agttggcagttctcctcctatgttggccgaggcctcaactcagaccagctgagcatgctg
agaaacaagctgttcgggcagaactgtaggactgaggatccattattgtcctgggctgac
ttcactaagcgagagagccctcctggcaagttaccattctggacatggctggacaaaatt
ctggagttggtacatgaccacctgaaggatctctggaatgatggacgcatcatgggcttt
gtgagtcggagccaggagcgccggctgctgaagaagaccatctctggcacctttctactg
cgcttcagtgaatcgtcagaagggggcattacctgctcctgggtggagcaccaggatgat
gacaaggtgctcatctactctgtgcaaccctacaccaaggaggtgctgcagtcactcccg
ctgactgaaatcatccgccattaccagttgctcactgaggagaatatacctgaaaaccca
ctgcgcttcctctatccccgaatcccccgggatgaagcttttgggtgctactaccaggag
aaagttaatctccaggaacggaggaaatacctgaaacacaggctcattgtggtctctaat
agacaggtggatgaagtgcaacaaccgctggagcttaagccagagccagagctggagtca
ttagagctggaactagggctggcgccagagccagagctcagccaggacttagagcaactg
ctgaaggcagggctggatctggggccagagctagaatctgtgctggagtccactctggag
cctgtgatagagcccacactatgcatggtatcacaaacagtgccagagccagaccgagga
cctgtatcacagccagtgccggagccagatttgccctgtgatctgagacatttgaacact
gagccaatggaaatcttcagaaactgtgtaaagattgaagaaatcatgctgaatggtgac
ccactgctggctggccagaacaccgtggatgaggtttacgtctcccgccccagtcacttc
tacactgatggacccttgatgccttctgaattctag

KEGG   Pongo abelii (Sumatran orangutan): 100461695
Entry
100461695         CDS       T01416                                 

Gene name
STAT5A
Definition
(RefSeq) signal transducer and activator of transcription 5A isoform X1
  KO
K11223  signal transducer and activator of transcription 5A
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04012  ErbB signaling pathway
pon04217  Necroptosis
pon04630  JAK-STAT signaling pathway
pon04658  Th1 and Th2 cell differentiation
pon04659  Th17 cell differentiation
pon04917  Prolactin signaling pathway
pon04933  AGE-RAGE signaling pathway in diabetic complications
pon04935  Growth hormone synthesis, secretion and action
pon05161  Hepatitis B
pon05162  Measles
pon05166  Human T-cell leukemia virus 1 infection
pon05200  Pathways in cancer
pon05203  Viral carcinogenesis
pon05220  Chronic myeloid leukemia
pon05221  Acute myeloid leukemia
pon05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100461695 (STAT5A)
   04630 JAK-STAT signaling pathway
    100461695 (STAT5A)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100461695 (STAT5A)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100461695 (STAT5A)
   04659 Th17 cell differentiation
    100461695 (STAT5A)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    100461695 (STAT5A)
   04935 Growth hormone synthesis, secretion and action
    100461695 (STAT5A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100461695 (STAT5A)
   05203 Viral carcinogenesis
    100461695 (STAT5A)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    100461695 (STAT5A)
   05220 Chronic myeloid leukemia
    100461695 (STAT5A)
   05223 Non-small cell lung cancer
    100461695 (STAT5A)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100461695 (STAT5A)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100461695 (STAT5A)
   05161 Hepatitis B
    100461695 (STAT5A)
   05162 Measles
    100461695 (STAT5A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100461695 (STAT5A)
Transcription factors [BR:pon03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100461695 (STAT5A)
SSDB
Motif
Pfam: STAT_bind STAT_alpha STAT_int SH2
Other DBs
NCBI-GeneID: 100461695
NCBI-ProteinID: XP_002827563
Ensembl: ENSPPYG00000008393
UniProt: A0A6D2WCR6 A0A2J8RF61
LinkDB
Position
17
AA seq 794 aa
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQKTYDRCPMELVRCIRHILYNEQRLV
REANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
SSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRL
GDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGGGSATY
MDQAPSPAVCPQAHYNLYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLS
PPAGLFTSARGSLS
NT seq 2385 nt   +upstreamnt  +downstreamnt
atggcgggctggatccaggcccagcagctgcagggagacgcgctgcgccagatgcaggtg
ctgtacggccagcacttccccatcgaggtccggcactacttggcccagtggattgagagc
cagccatgggatgccattgacttggacaatccccaggacagagcccaagccacccagctc
ctggagggcctggtgcaggagctgcagaagaaggcggagcaccaggtgggggaagatggg
tttttactgaagatcaagctggggcactatgccacgcagctccagaaaacgtatgaccgc
tgccccatggagctggtccgctgcatccggcacattctgtacaatgaacagaggctggtc
cgagaagccaacaattgcagctctccggctgggatcctggttgatgccatgtcccagaag
caccttcagatcaaccagacatttgaggagctgcgactggtcacgcaggacacagagaat
gagctgaagaagctgcagcagactcaggagtacttcatcatccagtaccaggaaagcctg
aggatccaagctcagtttggcccactggcccagctgagcccccaggagcgtctgagccgg
gagacggccctccagcagaagcaggtgtctctggaggcctggttgcagcgtgaggcacag
acgctgcagcagtaccgcgtggagctggccgagaagcaccagaagaccctgcagctgctg
cggaagcagcagaccatcatcctggatgacgagctgatccagtggaagcggcggcagcaa
ctggccgggaacggcgggccccccgaaggcagcctggacgtgctacagtcctggtgtgag
aagttggccgagatcatctggcagaaccggcagcagatccgcagggccgagcacctctgc
cagcagctgcccatccccggcccagtggaggagatgctggccgaggtcaacgccaccatc
acggacatcatctcagccctggtgaccagcacattcatcattgagaagcagcctcctcag
gtcctgaagacccagaccaagtttgcagccactgtgcgcctgctggtgggcgggaagctg
aacgtgcacatgaaccccccccaggtgaaggccaccatcatcagtgagcagcaggccaag
tctctgctcaagaacgagaacacccgcaatgagtgcagtggtgagatcctgaacaactgc
tgcgtgatggagtaccaccaagccacgggcaccctcagcgcccacttcaggaacatgtca
ctgaagaggatcaagcgtgctgaccggcggggtgcagagtccgtgacagaggagaagttc
acagtcctgtttgagtctcagttcagtgttggcagcaatgagcttgtgttccaggtgaag
actctgtccctacctgtggttgtcatcgtccacggcagccaggaccacaatgccacggcc
accgtgctgtgggacaacgcctttgctgagccgggcagggtgccatttgccgtgcctgac
aaagtgctgtggccacagctgtgtgaggcactcaacatgaaattcaaggccgaagtacag
agcaaccggggcctgaccaaggagaacctcgtgttcctggcccagaaactgttcaacaac
agcagcagccacctggaggactacagtggcctgtccgtgtcctggtcccagttcaacagg
gagaacttgccgggctggaactacaccttctggcagtggtttgacggggtgatggaggtg
ttgaagaagcaccacaagccccactggaatgatggggccatcctaggttttgtgaataag
caacaggcccatgacctgctcatcaacaagcccgatgggaccttcttgttgcgctttagt
gactcagaaatcgggggcatcaccatcgcctggaagtttgactccccggaacgcaacctg
tggaacctgaaaccattcaccacgcgggatttctccatcaggtccctggctgaccggctg
ggggacctgagctatctcatctatgtgtttcctgaccgccccaaggatgaggtcttctcc
aagtactacactcctgtgctggctaaagctgttgatggatatgtgaagccacagatcaag
caagtggtccctgagtttgtgaacgcatctgcagatgccgggggcggcagcgccacatac
atggaccaggccccctccccagctgtgtgcccccaggctcactataacttgtacccacag
aaccctgaccacgtactcgatcaggatggagaattcgacctggatgagaccatggatgtg
gccaggcacgtggaggaactcttacgccgaccaatggacagtcttgactcgcgcctctcg
ccccctgccggtcttttcacctctgccagaggctccctctcatga

KEGG   Pongo abelii (Sumatran orangutan): 100462537
Entry
100462537         CDS       T01416                                 

Gene name
STAT5B
Definition
(RefSeq) signal transducer and activator of transcription 5B isoform X1
  KO
K11224  signal transducer and activator of transcription 5B
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04012  ErbB signaling pathway
pon04062  Chemokine signaling pathway
pon04217  Necroptosis
pon04630  JAK-STAT signaling pathway
pon04658  Th1 and Th2 cell differentiation
pon04659  Th17 cell differentiation
pon04917  Prolactin signaling pathway
pon04933  AGE-RAGE signaling pathway in diabetic complications
pon04935  Growth hormone synthesis, secretion and action
pon05161  Hepatitis B
pon05162  Measles
pon05166  Human T-cell leukemia virus 1 infection
pon05200  Pathways in cancer
pon05203  Viral carcinogenesis
pon05220  Chronic myeloid leukemia
pon05221  Acute myeloid leukemia
pon05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100462537 (STAT5B)
   04630 JAK-STAT signaling pathway
    100462537 (STAT5B)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100462537 (STAT5B)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100462537 (STAT5B)
   04659 Th17 cell differentiation
    100462537 (STAT5B)
   04062 Chemokine signaling pathway
    100462537 (STAT5B)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    100462537 (STAT5B)
   04935 Growth hormone synthesis, secretion and action
    100462537 (STAT5B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100462537 (STAT5B)
   05203 Viral carcinogenesis
    100462537 (STAT5B)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    100462537 (STAT5B)
   05220 Chronic myeloid leukemia
    100462537 (STAT5B)
   05223 Non-small cell lung cancer
    100462537 (STAT5B)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100462537 (STAT5B)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100462537 (STAT5B)
   05161 Hepatitis B
    100462537 (STAT5B)
   05162 Measles
    100462537 (STAT5B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100462537 (STAT5B)
Transcription factors [BR:pon03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100462537 (STAT5B)
SSDB
Motif
Pfam: STAT_bind STAT_alpha STAT_int SH2
Other DBs
NCBI-GeneID: 100462537
NCBI-ProteinID: XP_002827565
Ensembl: ENSPPYG00000008394
UniProt: H2NU10
LinkDB
Position
17
AA seq 787 aa
MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSIDLDNPQENIKATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
SSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGG
GSATYMDQAPSPAVCSQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQ
WIPHAQS
NT seq 2364 nt   +upstreamnt  +downstreamnt
atggctgtgtggatacaagctcagcagctccaaggagaagcccttcatcagatgcaagcg
ttgtatggccagcattttcccattgaggtgcggcattatttatcccagtggattgaaagc
caagcatgggactcaatagatcttgataatccacaggagaacattaaggccacccagctc
ctggagggcctggtgcaggagctgcagaagaaggcagagcaccaggtgggggaagatggg
tttttactgaagatcaagctggggcactacgccacgcagctccagaacacgtatgaccgc
tgccccatggagctggtccgctgcatccgccatatattgtacaatgaacagaggttggtc
cgagaagctaacaatggtagctctccagctggaagccttgctgatgccatgtcccagaaa
cacctccagatcaaccagacatttgaggagctgcgactggtcacgcaggacacagagaat
gagttaaaaaagctgcagcagactcaggagtacttcatcatccagtaccaggaaagccta
aggatccaagctcagtttggcccgctggcccagctgagcccccaggagcgtctgagccgg
gagacggccctccagcagaagcaggtgtctctggaggcctggttgcagcgtgaggcacag
acgctgcagcagtaccgcgtggagctggccgagaagcaccagaagaccctgcagctgctg
cggaagcagcagaccatcatcctggatgacgagctgatccagtggaagcggcggcagcaa
ctggccgggaacggcgggccccccgaaggcagcctggacgtgctacagtcctggtgtgag
aagttggccgagatcatctggcagaaccggcagcagatccgcagggccgagcacctctgc
cagcagctgcccatccccggcccagtggaggagatgctggccgaggtcaacgccaccatc
acggacatcatctcagccctggtgaccagcacattcatcattgagaagcagcctcctcag
gtcctgaagacccagaccaagtttgcagccactgtgcgcctgctggtgggcgggaagctg
aacgtgcacatgaaccccccccaggtgaaggccaccatcatcagtgagcagcaggccaag
tctctgctcaagaacgagaacacccgcaatgattacagtggcgagatcttgaacaactgc
tgcgtcatggagtaccaccaagccacaggcacccttagtgcccacttcaggaatatgtcc
ctgaaacgaattaagaggtcagaccgtcgtggggcagagtcggtgacagaagaaaaattt
acaatcctgtttgaatcccagttcagtgttggtggaaatgagctggtttttcaagtcaag
accctgtccctgccagtggtggtgatcgttcatggcagccaggacaacaatgcgacggcc
accgttctctgggacaatgcttttgcagagcctggcagggtgccatttgccgtgcctgac
aaagtgctgtggccacagctgtgtgaggcactcaacatgaaattcaaggctgaagtgcag
agcaaccggggcctgaccaaggagaacctcgtgttcctggcgcagaaactgttcaacaac
agcagcagccacctggaggactacagtggcctgtccgtgtcctggtcccagttcaacagg
gagaatttaccaggacggaattacactttctggcaatggtttgacggtgtgatggaagtg
ttaaaaaaacatctcaagcctcattggaatgatggggccattttggggtttgtaaacaag
caacaggcccatgacctactcattaacaagccagatgggaccttcctgctgagattcagt
gactcagaaattggcggcatcaccattgcttggaagtttgattctcaggaaagaatgttt
tggaatctgatgccttttaccaccagagacttctccattcggtccctagccgaccgcttg
ggagacttgaattaccttatctacgtgtttcctgatcggccaaaagatgaagtatactcc
aaatactacacaccagttccctgcgagtctgctactgctaaagctgttgatggatacgtg
aagccacagatcaagcaagtggtccctgagtttgtgaacgcatctgcagatgctgggggt
ggcagcgccacgtacatggaccaggccccctccccagctgtgtgctcccaggctcactat
aacatgtacccacagaaccctgactctgtccttgacaccgatggggacttcgatctggag
gacacaatggatgtagcgcggcgtgtggaggagctcctgggccggccaatggacagtcag
tggatcccgcacgcacagtcgtga

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