Pongo abelii (Sumatran orangutan): 100171625 Help Entry 100171625         CDS       T01416                                  Gene name CCND1 Definition (RefSeq) G1/S-specific cyclin-D1   KO K04503   G1/S-specific cyclin-D1 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon01522   Endocrine resistance pon04068   FoxO signaling pathway pon04110   Cell cycle pon04115   p53 signaling pathway pon04151   PI3K-Akt signaling pathway pon04152   AMPK signaling pathway pon04218   Cellular senescence pon04310   Wnt signaling pathway pon04340   Hedgehog signaling pathway pon04371   Apelin signaling pathway pon04390   Hippo signaling pathway pon04510   Focal adhesion pon04530   Tight junction pon04630   JAK-STAT signaling pathway pon04917   Prolactin signaling pathway pon04919   Thyroid hormone signaling pathway pon04921   Oxytocin signaling pathway pon04933   AGE-RAGE signaling pathway in diabetic complications pon04934   Cushing syndrome pon05160   Hepatitis C pon05162   Measles pon05163   Human cytomegalovirus infection pon05165   Human papillomavirus infection pon05166   Human T-cell leukemia virus 1 infection pon05167   Kaposi sarcoma-associated herpesvirus infection pon05169   Epstein-Barr virus infection pon05200   Pathways in cancer pon05203   Viral carcinogenesis pon05205   Proteoglycans in cancer pon05206   MicroRNAs in cancer pon05210   Colorectal cancer pon05212   Pancreatic cancer pon05213   Endometrial cancer pon05214   Glioma pon05215   Prostate cancer pon05216   Thyroid cancer pon05218   Melanoma pon05219   Bladder cancer pon05220   Chronic myeloid leukemia pon05221   Acute myeloid leukemia pon05222   Small cell lung cancer pon05223   Non-small cell lung cancer pon05224   Breast cancer pon05225   Hepatocellular carcinoma pon05226   Gastric cancer pon05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100171625 (CCND1)    04340 Hedgehog signaling pathway     100171625 (CCND1)    04390 Hippo signaling pathway     100171625 (CCND1)    04371 Apelin signaling pathway     100171625 (CCND1)    04630 JAK-STAT signaling pathway     100171625 (CCND1)    04068 FoxO signaling pathway     100171625 (CCND1)    04151 PI3K-Akt signaling pathway     100171625 (CCND1)    04152 AMPK signaling pathway     100171625 (CCND1)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     100171625 (CCND1)    04115 p53 signaling pathway     100171625 (CCND1)    04218 Cellular senescence     100171625 (CCND1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100171625 (CCND1)    04530 Tight junction     100171625 (CCND1)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     100171625 (CCND1)    04921 Oxytocin signaling pathway     100171625 (CCND1)    04919 Thyroid hormone signaling pathway     100171625 (CCND1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100171625 (CCND1)    05206 MicroRNAs in cancer     100171625 (CCND1)    05205 Proteoglycans in cancer     100171625 (CCND1)    05203 Viral carcinogenesis     100171625 (CCND1)   09162 Cancer: specific types    05210 Colorectal cancer     100171625 (CCND1)    05212 Pancreatic cancer     100171625 (CCND1)    05225 Hepatocellular carcinoma     100171625 (CCND1)    05226 Gastric cancer     100171625 (CCND1)    05214 Glioma     100171625 (CCND1)    05216 Thyroid cancer     100171625 (CCND1)    05221 Acute myeloid leukemia     100171625 (CCND1)    05220 Chronic myeloid leukemia     100171625 (CCND1)    05218 Melanoma     100171625 (CCND1)    05219 Bladder cancer     100171625 (CCND1)    05215 Prostate cancer     100171625 (CCND1)    05213 Endometrial cancer     100171625 (CCND1)    05224 Breast cancer     100171625 (CCND1)    05222 Small cell lung cancer     100171625 (CCND1)    05223 Non-small cell lung cancer     100171625 (CCND1)   09166 Cardiovascular disease    05416 Viral myocarditis     100171625 (CCND1)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100171625 (CCND1)    04934 Cushing syndrome     100171625 (CCND1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100171625 (CCND1)    05160 Hepatitis C     100171625 (CCND1)    05162 Measles     100171625 (CCND1)    05163 Human cytomegalovirus infection     100171625 (CCND1)    05167 Kaposi sarcoma-associated herpesvirus infection     100171625 (CCND1)    05169 Epstein-Barr virus infection     100171625 (CCND1)    05165 Human papillomavirus infection     100171625 (CCND1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100171625 (CCND1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Cyclin_N Cyclin_C Motif Other DBs NCBI-GeneID:  100171625 NCBI-ProteinID:  NP_001124773 UniProt:  Q5R6J5 A0A2J8U0V4 LinkDB All DBs Position 11 AA seq 295 aa AA seqDB search MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAALTPHDFIEHFLSKMPEAEENKQIIRK HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNSFLSYYRLTRFLSRVIKCD PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI NT seq 888 nt NT seq  +upstreamnt  +downstreamnt atggaacaccagctcctgtgctgcgaagtggaaaccatccgccgcgcgtaccccgatgcc aacctcctcaacgaccgggtgctgcgggccatgctgaaggcggaggagacctgcgcgccc tcggtgtcctacttcaaatgtgtgcagaaggaggtcctgccgtccatgcggaagatcgtc gccacctggatgctggaggtctgcgaggagcagaagtgcgaggaggaggtcttcccgctg gccatgaactacctggaccgcttcctgtcgctggagcccgtgaagaagagccgactgcag ctgctaggggccacttgcatgttcgtggcctctaagatgaaggagaccatccccctgacg gccgagaagctatgcatctacaccgacaactccatccggcccgaggagctgctgcaaatg gagctgctcctggtgaacaagctcaagtggaacctggccgccttgaccccgcacgatttc attgaacacttcctctccaaaatgccagaggcggaggagaacaaacagatcatccgcaaa cacgcgcagaccttcgttgccctctgtgccacagatgtgaagttcatttccaatccaccc tccatggtagcagcggggagcgtggtggccgcagtgcaaggcctgaacctgaggagcccc aacagcttcctgtcctactaccgcctcacacgcttcctctccagagtgatcaagtgtgac ccggactgcctccgggcctgccaggagcagatcgaagccctgctggagtcaagcctgcgc caggcccagcagaacatggaccccaaggccgccgaggaggaggaagaggaggaggaggag gtggacctggcttgcacacccaccgacgtgcgggacgtggacatctga

Pongo abelii (Sumatran orangutan): 100452570 Help Entry 100452570         CDS       T01416                                  Gene name CCND3 Definition (RefSeq) G1/S-specific cyclin-D3 isoform X1   KO K10152   G1/S-specific cyclin-D3 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04110   Cell cycle pon04115   p53 signaling pathway pon04151   PI3K-Akt signaling pathway pon04218   Cellular senescence pon04310   Wnt signaling pathway pon04390   Hippo signaling pathway pon04510   Focal adhesion pon04630   JAK-STAT signaling pathway pon05162   Measles pon05164   Influenza A pon05165   Human papillomavirus infection pon05166   Human T-cell leukemia virus 1 infection pon05169   Epstein-Barr virus infection pon05200   Pathways in cancer pon05203   Viral carcinogenesis Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100452570 (CCND3)    04390 Hippo signaling pathway     100452570 (CCND3)    04630 JAK-STAT signaling pathway     100452570 (CCND3)    04151 PI3K-Akt signaling pathway     100452570 (CCND3)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     100452570 (CCND3)    04115 p53 signaling pathway     100452570 (CCND3)    04218 Cellular senescence     100452570 (CCND3)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100452570 (CCND3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100452570 (CCND3)    05203 Viral carcinogenesis     100452570 (CCND3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100452570 (CCND3)    05164 Influenza A     100452570 (CCND3)    05162 Measles     100452570 (CCND3)    05169 Epstein-Barr virus infection     100452570 (CCND3)    05165 Human papillomavirus infection     100452570 (CCND3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Cyclin_N Cyclin_C K-cyclin_vir_C Motif Other DBs NCBI-GeneID:  100452570 NCBI-ProteinID:  XP_002816925 Ensembl:  ENSPPYG00000016607 UniProt:  A0A6D2YAM4 H2PJ14 LinkDB All DBs Position 6 AA seq 292 aa AA seqDB search MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPRDRQALVKK HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL RACQEQIEAALRESLREAAQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL NT seq 879 nt NT seq  +upstreamnt  +downstreamnt atggagctgctgtgttgcgaaggcacccggcacgcgccccgggccgggccggacccgcgg ctcctgggggaccagcgtgtcctgcagagcctactccgcctggaggagcgctacgtaccc cgcgcctcctacttccagtgcgtgcagcgggagatcaagccgcacatgcggaagatgctg gcttactggatgctggaggtatgtgaggaacagcgctgtgaggaggaagtcttccccctg gccatgaactacctggatcgctacttgtcctgcgtccccacccgaaaggcgcagttgcag ctcctgggtgcggtctgcatgctgctggcctccaagctgcgcgagaccacgcccctgacc atcgaaaaactgtgcatctacaccgaccacgctgtctctccccgccagttgcgggactgg gaggtgctggtcctagggaagctcaagtgggacctggctgctgtgattgcacatgatttc ctggccctcattctgcaccggctctctctgccccgtgaccgacaggccttggtcaaaaag cacgcccagacctttttggccctctgtgctacagattatacctttgccatgtacccgcca tccatgatcgccacgggcagcattggagctgcagtgcaaggcctgggtgcctgctccatg tccggggatgagctcacagagctgctggcagggatcactggcactgaagtggactgcctg cgggcctgtcaggagcagatcgaagctgcactcagggagagcctcagggaagctgctcag accagctccagcccagcgcccaaagccccccggggctccagcagccaagggcccagccag accagcactcctacagatgtcacagccatacacctgtag

Pongo abelii (Sumatran orangutan): 100457978 Help Entry 100457978         CDS       T01416                                  Gene name CCND2 Definition (RefSeq) G1/S-specific cyclin-D2   KO K10151   G1/S-specific cyclin-D2 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04068   FoxO signaling pathway pon04110   Cell cycle pon04115   p53 signaling pathway pon04151   PI3K-Akt signaling pathway pon04218   Cellular senescence pon04310   Wnt signaling pathway pon04340   Hedgehog signaling pathway pon04390   Hippo signaling pathway pon04510   Focal adhesion pon04630   JAK-STAT signaling pathway pon04917   Prolactin signaling pathway pon05162   Measles pon05165   Human papillomavirus infection pon05166   Human T-cell leukemia virus 1 infection pon05169   Epstein-Barr virus infection pon05200   Pathways in cancer pon05202   Transcriptional misregulation in cancer pon05203   Viral carcinogenesis pon05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100457978 (CCND2)    04340 Hedgehog signaling pathway     100457978 (CCND2)    04390 Hippo signaling pathway     100457978 (CCND2)    04630 JAK-STAT signaling pathway     100457978 (CCND2)    04068 FoxO signaling pathway     100457978 (CCND2)    04151 PI3K-Akt signaling pathway     100457978 (CCND2)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     100457978 (CCND2)    04115 p53 signaling pathway     100457978 (CCND2)    04218 Cellular senescence     100457978 (CCND2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100457978 (CCND2)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     100457978 (CCND2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100457978 (CCND2)    05202 Transcriptional misregulation in cancer     100457978 (CCND2)    05206 MicroRNAs in cancer     100457978 (CCND2)    05203 Viral carcinogenesis     100457978 (CCND2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100457978 (CCND2)    05162 Measles     100457978 (CCND2)    05169 Epstein-Barr virus infection     100457978 (CCND2)    05165 Human papillomavirus infection     100457978 (CCND2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Cyclin_N Cyclin_C K-cyclin_vir_C Motif Other DBs NCBI-GeneID:  100457978 NCBI-ProteinID:  XP_002822829 Ensembl:  ENSPPYG00000004164 UniProt:  A0A6D2XDY7 A0A2J8TAW1 LinkDB All DBs Position 12 AA seq 289 aa AA seqDB search MELLCCEVDPVRRAVRDRNLLQDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL NT seq 870 nt NT seq  +upstreamnt  +downstreamnt atggagctgctgtgctgcgaggtggacccggtccgcagggccgtgcgggaccgcaacctg ctccaagacgaccgcgtcctgcagaacctgctcaccatcgaggagcgctaccttccgcag tgctcctacttcaagtgcgtgcagaaggacatccaaccctacatgcgcagaatggtggcc acctggatgctggaggtctgtgaggaacagaagtgcgaagaagaggtcttccctctggcc atgaattacctggaccgtttcttggctggggtcccgactccgaagtcccatctgcaactc ctgggtgctgtctgcatgttcctggcctccaaactcaaagagaccagcccgctgactgcg gagaagctgtgcatttacaccgacaactccatcaagcctcaggagctgctggagtgggaa ctggtggtgctggggaagttgaagtggaacctggcagctgtcactcctcatgacttcatt gagcacatcttgcgcaagctgccccagcagcgggagaagctgtctctgatccgcaagcat gcccagaccttcattgctctgtgtgccaccgactttaagtttgccatgtacccaccgtcg atgatcgcaacaggaagtgtgggagcagccatctgtgggctccagcaggatgaggaagtg agctcgctcacttgtgatgccctgactgagctgctggctaagatcaccaacacagacgtg gattgtctcaaagcttgccaggagcagattgaggcggtgctcctcaatagcctgcagcag taccgtcaggaccaacgtgacggatccaagtcggaggatgaactggaccaagccagcacc cctacagacgtgcgggatatcgacctgtga

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