KEGG   Pongo abelii (Sumatran orangutan): 100172601
Entry
100172601         CDS       T01416                                 

Gene name
PCK2
Definition
(RefSeq) phosphoenolpyruvate carboxykinase [GTP], mitochondrial
  KO
K01596  phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00010  Glycolysis / Gluconeogenesis
pon00020  Citrate cycle (TCA cycle)
pon00620  Pyruvate metabolism
pon01100  Metabolic pathways
pon03320  PPAR signaling pathway
pon04068  FoxO signaling pathway
pon04151  PI3K-Akt signaling pathway
pon04152  AMPK signaling pathway
pon04910  Insulin signaling pathway
pon04920  Adipocytokine signaling pathway
pon04922  Glucagon signaling pathway
pon04931  Insulin resistance
pon04964  Proximal tubule bicarbonate reclamation
Module
pon_M00003  Gluconeogenesis, oxaloacetate => fructose-6P
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100172601 (PCK2)
   00020 Citrate cycle (TCA cycle)
    100172601 (PCK2)
   00620 Pyruvate metabolism
    100172601 (PCK2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    100172601 (PCK2)
   04151 PI3K-Akt signaling pathway
    100172601 (PCK2)
   04152 AMPK signaling pathway
    100172601 (PCK2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100172601 (PCK2)
   04922 Glucagon signaling pathway
    100172601 (PCK2)
   04920 Adipocytokine signaling pathway
    100172601 (PCK2)
   03320 PPAR signaling pathway
    100172601 (PCK2)
  09155 Excretory system
   04964 Proximal tubule bicarbonate reclamation
    100172601 (PCK2)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100172601 (PCK2)
Enzymes [BR:pon01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.32  phosphoenolpyruvate carboxykinase (GTP)
     100172601 (PCK2)
SSDB
Motif
Pfam: PEPCK_GTP PEPCK_N
Other DBs
NCBI-GeneID: 100172601
NCBI-ProteinID: NP_001125680
Ensembl: ENSPPYG00000005679
UniProt: Q5RAP7
LinkDB
Position
14
AA seq 506 aa
MSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRL
GTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSKWPCNPEKTLIGHVPDQREIVSFGSGYG
GNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAAAFPSACGKTNLAMM
RPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTI
FTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKHWKPGDKEPCAHPNSRFCAPARQCPIM
DPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKIIM
HDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEAGHFLWPGFGENARV
LDWICRRLEGEDSARETPIGLVPKEGALDLSGLGAIDTTQLFSLPKDFWEQEVRDIRSCL
IEQVNQDLPKEVLAELEALERRVHKM
NT seq 1521 nt   +upstreamnt  +downstreamnt
atgtccccagctgatttccagcgagctgtggatgagaggtttccaggctgcatgcagggc
cgcaccatgtacgtgcttccattcagcatgggtcctgtgggctccccgctgtcccgcatc
ggggtgcagctcactgactcagcctatgtggtagcaagcatgcgtattatgacccgactg
gggacacccgtgcttcaggccctgggagatggtgactttgtcaagtgtctgcactccgtg
ggccagcccctgacaggacaaggggagccggtgagcaagtggccgtgcaacccagagaaa
accctgattggccacgtgcccgaccagcgggagatcgtctccttcggcagcggctatggt
ggcaactccctgctgggcaagaagtgctttgccctacgcatcgcctctcggctggcccgg
gatgagggctggctggcagagcacatgctgatcctgggcatcactagccctgcagggaag
aagcgctatgtggcagccgccttccctagtgcctgtggcaagaccaacctggctatgatg
cggcccgcactgccaggctggaaagtggagtgtgtgggggatgacattgcttggatgagg
tttgacagtgaaggtcgactccgggccatcaaccctgagaatggcttctttggggttgcc
cctggtacctctgccaccaccaatcccaacgccatggctacaatccagagtaacactatt
tttaccaatgtggctgagaccagcgatggtggcgtgtactgggagggcattgaccagcct
cttccacccggtgttactgtgacctcctggctgggcaaacactggaaacctggtgacaag
gagccctgtgcacatcccaactctcgattttgtgccccggctcgccagtgccccatcatg
gacccagcctgggaggccccagagggtgtccccattgacgccatcatctttggtggccgc
agaccaaaaggggtacccctggtatacgaggccttcaactggcgtcatggggtgtttgtg
ggcagcgccatgcgctctgagtccactgctgcagcagaacacaaagggaagatcatcatg
cacgacccatttgccatgcggcccttttttggctacaacttcgggcactacctggaacac
tggctgagcatggaagggcgcaagggggcccagctgccccgtatcttccatgtcaactgg
ttccggcgtgatgaggcagggcacttcctgtggccaggctttggggagaatgctcgggtg
ctagactggatctgccggcggttagagggggaggacagtgcccgagagacacccattggg
ctggtgccaaaggaaggagccttggatctcagcggtctcggagctatagacaccactcag
ctgttctccctccccaaggacttctgggaacaggaggttcgtgacattcggagctgcctg
atagagcaggtcaaccaagatctgcccaaagaggtgttggctgagcttgaagccctggag
agacgtgtgcacaaaatgtga

KEGG   Pongo abelii (Sumatran orangutan): 100173760
Entry
100173760         CDS       T01416                                 

Gene name
PCK1
Definition
(RefSeq) phosphoenolpyruvate carboxykinase, cytosolic [GTP]
  KO
K01596  phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00010  Glycolysis / Gluconeogenesis
pon00020  Citrate cycle (TCA cycle)
pon00620  Pyruvate metabolism
pon01100  Metabolic pathways
pon03320  PPAR signaling pathway
pon04068  FoxO signaling pathway
pon04151  PI3K-Akt signaling pathway
pon04152  AMPK signaling pathway
pon04910  Insulin signaling pathway
pon04920  Adipocytokine signaling pathway
pon04922  Glucagon signaling pathway
pon04931  Insulin resistance
pon04964  Proximal tubule bicarbonate reclamation
Module
pon_M00003  Gluconeogenesis, oxaloacetate => fructose-6P
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100173760 (PCK1)
   00020 Citrate cycle (TCA cycle)
    100173760 (PCK1)
   00620 Pyruvate metabolism
    100173760 (PCK1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    100173760 (PCK1)
   04151 PI3K-Akt signaling pathway
    100173760 (PCK1)
   04152 AMPK signaling pathway
    100173760 (PCK1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100173760 (PCK1)
   04922 Glucagon signaling pathway
    100173760 (PCK1)
   04920 Adipocytokine signaling pathway
    100173760 (PCK1)
   03320 PPAR signaling pathway
    100173760 (PCK1)
  09155 Excretory system
   04964 Proximal tubule bicarbonate reclamation
    100173760 (PCK1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100173760 (PCK1)
Enzymes [BR:pon01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.32  phosphoenolpyruvate carboxykinase (GTP)
     100173760 (PCK1)
SSDB
Motif
Pfam: PEPCK_GTP PEPCK_N
Other DBs
NCBI-GeneID: 100173760
NCBI-ProteinID: NP_001126758
Ensembl: ENSPPYG00000011164
UniProt: Q5R5J1
LinkDB
Position
20
AA seq 622 aa
MPPQLQNGLNLSAKVVQGSLDSLPQAVRKFLENNAELCQPDHIHICDGSEEENGRLLGQM
EEEGILRRLKKYDNCWLALTDPRDVARIGSKTVIVTQEQRDTVPIPKTGLSQLGRWMSEE
DFEKALNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPV
LEALGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSL
LGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSL
PGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNV
AETSDGGVYWEGIDEPLASGVTITSWKNKEWSPEDGEPCAHPNSRFCTPASQCPIIDAAW
ESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPF
AMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWM
FNRIDGKAGAKLTPIGYIPKEDALNLKGLGHINVMELFSISKEFWEKEVEDIEKYLEDQV
NADLPCEIEREILALKQRISQM
NT seq 1869 nt   +upstreamnt  +downstreamnt
atgcctcctcagctgcaaaacggcctgaacctctcggccaaagttgtccagggaagcctg
gacagcctgccccaggcagtgaggaagtttctcgagaataacgctgagctgtgtcagcct
gatcacatccacatctgcgacggctctgaggaggagaatgggcggcttctgggccagatg
gaggaggagggcatcctcaggcggctgaagaagtatgacaactgctggttggctctcact
gaccccagggatgtggccaggatcggaagcaagacggttatcgtcacccaagagcaaaga
gacacagtgcccatccccaaaacaggcctcagccagctcggtcgctggatgtcagaggag
gattttgagaaagcgctcaatgccaggttcccagggtgcatgaaaggtcgcaccatgtat
gtcatcccattcagcatggggccgctgggctcgcctctgtcgaagatcggcatcgagctg
acagattcaccctacgtggtggccagcatgcggatcatgacgcggatgggcacgcccgtc
ctggaagcactgggcgatggggagtttgtcaaatgcctccattctgtggggtgccctctg
cctttacaaaagcctttggtcaacaactggccctgcaacccggagctgacgctcatcgcc
cacctgcctgaccgcagagagatcatctcctttggcagtgggtatggcgggaactcgctg
ctcgggaagaagtgctttgctctcaggatggccagccggctggccaaggaggaaggatgg
ctggcagagcacatgctgattctgggtataaccaaccctgagggtgagaagaagtacctg
gcggccgcatttcccagcgcctgcgggaagaccaacctggccatgatgaaccccagcctc
cccgggtggaaggttgagtgcgtcggggatgacattgcctggatgaagtttgacgcacaa
ggtcatttaagggctatcaacccagaaaatggctttttcggtgtcgctcctgggacttca
gtgaagaccaaccccaatgccatcaagaccatccagaagaacaccatctttaccaatgtg
gccgagaccagcgacgggggcgtttactgggaaggcattgatgagccgctagcttcaggc
gtcaccatcacttcctggaagaataaggagtggagcccagaggatggggaaccttgtgcc
caccccaactccaggttctgcaccccagccagccagtgccccatcattgatgctgcctgg
gagtctccggaaggtgttcccattgaaggcattatctttggaggccgtagacctgctggt
gtccctctagtctatgaagctctcagctggcaacatggagtctttgtgggggcggccatg
agatcagaggccacagcagctgcagaacataaaggcaaaatcatcatgcatgaccccttt
gccatgcggcccttctttggctacaactttggcaaatacctggcccactggcttagcatg
gcccagcacccagcagccaaactgcccaagatcttccatgtcaactggttccggaaggac
aaggaaggcaaattcctctggccaggctttggagagaactccagggtgctggagtggatg
ttcaaccgcatcgatgggaaagccggtgccaagctcacacccataggctacatccccaag
gaggatgccctgaatctgaaaggcctggggcacatcaacgtgatggagctcttcagcatc
tccaaggaattctgggagaaggaggtggaagacatcgagaagtatctggaggatcaggtc
aatgctgacctcccctgtgaaattgagagagagatccttgccttgaagcaaagaataagc
cagatgtaa

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