Pongo abelii (Sumatran orangutan): 100172676 Help Entry 100172676         CDS       T01416                                  Gene name TRAF1 Definition (RefSeq) TNF receptor-associated factor 1   KO K03172   TNF receptor-associated factor 1 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04064   NF-kappa B signaling pathway pon04210   Apoptosis pon04668   TNF signaling pathway pon05200   Pathways in cancer pon05202   Transcriptional misregulation in cancer pon05203   Viral carcinogenesis pon05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100172676 (TRAF1)    04668 TNF signaling pathway     100172676 (TRAF1)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100172676 (TRAF1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100172676 (TRAF1)    05202 Transcriptional misregulation in cancer     100172676 (TRAF1)    05203 Viral carcinogenesis     100172676 (TRAF1)   09162 Cancer: specific types    05222 Small cell lung cancer     100172676 (TRAF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF_BIRC3_bd Motif Other DBs NCBI-GeneID:  100172676 NCBI-ProteinID:  NP_001125751 Ensembl:  ENSPPYG00000019557 UniProt:  Q5RAE4 LinkDB All DBs Position 9 AA seq 416 aa AA seqDB search MASSSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCTGCLSENPRNGEDQICSKCRGE DLQSISPGSRLRTQEKAHPEVAEAGVGCPFAGVGCSFKGSPQSVQEHEVTSQTSHLNLLL GFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQEELALQH FMKEKLLAELEGKLRVFENIVAVLDKEVEASHLALATSIHQSQLDRERILSLEQRVVEPQ QTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAK YGYKLCLRLYLNGDGTGKRTHLSLFIVLMRGEYDALLPWPFRNKVTFMLLDQNNREHAID AFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETST NT seq 1251 nt NT seq  +upstreamnt  +downstreamnt atggcctccagctcaggcagcagccctcgcccggcccctgatgagaatgagtttcccttt gggtgccctcccaccgtctgccaggacccaaaggagcccagggctctctgctgtacaggc tgtctctctgagaacccgaggaacggcgaggatcagatctgctccaaatgcagaggggaa gacctccagtctataagcccaggaagccgtcttcgaactcaggagaaggctcaccccgag gtggccgaggctggagttgggtgcccctttgcaggtgtcggctgctccttcaagggaagc ccacagtctgtgcaagagcatgaggtcacctcccagacctcccacctaaacctgctgctg gggttcatgaaacagtggaaggcccggctgggctgtggcctggagtctgggcccatggcc ctggagcagaacctgtcagacctgcagctgcaggcagccgtggaagtggcgggggacctg gaggtcgattgctaccgggcaccctgctccgagagccaggaggagctggccctgcagcac ttcatgaaggagaagcttctggctgagctggaggggaagctgcgtgtgtttgagaatatt gttgctgttctcgacaaggaggtggaggcctcccacctggccctggccacctccatccac cagagccagctggaccgtgagcgcatcctgagcttggagcagagggtggtggagccgcag cagaccctggcccagaaagaccaggccctgggcaagctggagcagagcttgcgcctcatg gaggaggcctccttcgatggcaccttcctgtggaagatcaccaacgtcaccaggcggtgc catgagtcggcctgtggcaggaccgtcagcctcttctccccagccttctacactgccaag tatggctacaagttgtgcctgcggctgtacctgaatggagatggcactggaaagaggacc cacctgtcgctcttcatcgtgctcatgcgaggggagtatgatgcgctgctgccgtggcct ttccgaaacaaggtcaccttcatgctgctggaccagaacaaccgtgagcacgccattgac gccttccggcctgacctaagctcagcatccttccagaggccccagagtgaaaccaatgtg gccagtggctgcccactcttctttcccctcagcaaactgcagtcacccaagcacgcctat gtgaaggacgacacgatgtttctcaagtgcattgtggagaccagcacttag

Pongo abelii (Sumatran orangutan): 100431446 Help Entry 100431446         CDS       T01416                                  Gene name TRAF4 Definition (RefSeq) TNF receptor-associated factor 4   KO K09848   TNF receptor-associated factor 4 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04657   IL-17 signaling pathway pon05200   Pathways in cancer pon05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:pon00001]  09150 Organismal Systems   09151 Immune system    04657 IL-17 signaling pathway     100431446 (TRAF4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100431446 (TRAF4)   09162 Cancer: specific types    05222 Small cell lung cancer     100431446 (TRAF4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-TRAF zf-C3HC4 zf-C3HC4_2 zf-RING_UBOX zf-Nse zf-C3HC4_4 zf-RING_5 zf-RING_2 zf-RING_6 zf-C3HC4_3 zf-TRAF_2 zf-rbx1 Sina Motif Other DBs NCBI-GeneID:  100431446 NCBI-ProteinID:  XP_024090790 Ensembl:  ENSPPYG00000008111 LinkDB All DBs Position 17 AA seq 470 aa AA seqDB search MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLP LDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMK LSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLL AQHATSECPKRTQPCTYCSKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLK DSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELE ELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEG THLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKP GTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKILS NT seq 1413 nt NT seq  +upstreamnt  +downstreamnt atgcctggcttcgactacaagttcttggagaagcccaagcgacggctgctatgcccactg tgcgggaagcccatgcgcgagcctgtgcaggtttccacctgcggccaccgtttctgcgac acctgcctgcaggagttcctcagtgaaggagtcttcaagtgccctgaggaccagcttcct ctggactatgccaagatctacccagacccggagctggaagtacaagtattgggcctgcct atccgctgcatccacagtgaggagggctgccgctggagtgggccactacgtcatctacag ggccacctgaatacctgcagcttcaacgtcattccctgccctaatcgctgccccatgaag ctgagccgccgtgatctacctgcacacttgcagcacgactgccccaagcggcgcctcaag tgcgagttttgtggctgtgacttcagtggggaggcctatgagagccatgagggtatgtgc ccccaggagagtgtctactgtgagaataagtgtggtgcccgcatgatgcggcggctgctg gcccagcatgccacctctgagtgccccaagcgcactcagccctgcacttactgcagtaag gagttcgtctttgacaccatccagagccaccagtaccagtgcccaaggctgcctgttgcc tgccccaaccagtgtggtgtgggcactgtggctcgggaggacctgccaggccatctgaag gacagctgtaacaccgccctggtgctctgcccattcaaagactccggctgcaagcacagg tgccctaagctggcaatggcacggcatgtggaggagagtgtgaagccacatctggccatg atgtgtgccctggtgagccggcaacggcaggagctgcaggagcttcggcgagagctggag gagctatcagtgggcagtgatggcgtgctcatctggaagattggcagctatggacgacgg ttacaggaggccaaggccaagcccaaccttgagtgcttcagcccagccttctacacacat aagtatggttacaagctgcaggtgtctgcattcctcaatggcaatggcagtggcgagggc acacacctctcgctgtacattcgtgtgctgcctggtgcctttgacaatctccttgagtgg ccctttgcccgccgtgtcaccttctccctgctggatcagagcgaccctgggctggctaaa ccacagcacgtcaccgagaccttccaccccgacccaaactggaagaatttccagaagccg ggcacatggcggggctccctggatgagagttctctgggctttggttatcccaagttcatc tcccaccaggacattcgaaagcgaaactatgtgcgggatgatgcagtcttcatccgtgct gctgttgaactgccccggaagatcctcagctga

Pongo abelii (Sumatran orangutan): 100449432 Help Entry 100449432         CDS       T01416                                  Gene name TRAF6 Definition (RefSeq) TNF receptor-associated factor 6   KO K03175   TNF receptor-associated factor 6 [EC:2.3.2.27] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04010   MAPK signaling pathway pon04064   NF-kappa B signaling pathway pon04120   Ubiquitin mediated proteolysis pon04140   Autophagy - animal pon04144   Endocytosis pon04380   Osteoclast differentiation pon04620   Toll-like receptor signaling pathway pon04621   NOD-like receptor signaling pathway pon04622   RIG-I-like receptor signaling pathway pon04657   IL-17 signaling pathway pon04722   Neurotrophin signaling pathway pon05132   Salmonella infection pon05133   Pertussis pon05135   Yersinia infection pon05140   Leishmaniasis pon05142   Chagas disease pon05145   Toxoplasmosis pon05152   Tuberculosis pon05160   Hepatitis C pon05161   Hepatitis B pon05162   Measles pon05168   Herpes simplex virus 1 infection pon05169   Epstein-Barr virus infection pon05170   Human immunodeficiency virus 1 infection pon05171   Coronavirus disease - COVID-19 pon05200   Pathways in cancer pon05222   Small cell lung cancer pon05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:pon00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     100449432 (TRAF6)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100449432 (TRAF6)    04064 NF-kappa B signaling pathway     100449432 (TRAF6)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     100449432 (TRAF6)    04140 Autophagy - animal     100449432 (TRAF6)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100449432 (TRAF6)    04621 NOD-like receptor signaling pathway     100449432 (TRAF6)    04622 RIG-I-like receptor signaling pathway     100449432 (TRAF6)    04657 IL-17 signaling pathway     100449432 (TRAF6)   09156 Nervous system    04722 Neurotrophin signaling pathway     100449432 (TRAF6)   09158 Development and regeneration    04380 Osteoclast differentiation     100449432 (TRAF6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100449432 (TRAF6)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100449432 (TRAF6)   09162 Cancer: specific types    05222 Small cell lung cancer     100449432 (TRAF6)   09171 Infectious disease: bacterial    05132 Salmonella infection     100449432 (TRAF6)    05135 Yersinia infection     100449432 (TRAF6)    05133 Pertussis     100449432 (TRAF6)    05152 Tuberculosis     100449432 (TRAF6)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100449432 (TRAF6)    05161 Hepatitis B     100449432 (TRAF6)    05160 Hepatitis C     100449432 (TRAF6)    05171 Coronavirus disease - COVID-19     100449432 (TRAF6)    05162 Measles     100449432 (TRAF6)    05168 Herpes simplex virus 1 infection     100449432 (TRAF6)    05169 Epstein-Barr virus infection     100449432 (TRAF6)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100449432 (TRAF6)    05140 Leishmaniasis     100449432 (TRAF6)    05142 Chagas disease     100449432 (TRAF6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pon04131]     100449432 (TRAF6)    04121 Ubiquitin system [BR:pon04121]     100449432 (TRAF6) Enzymes [BR:pon01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      100449432 (TRAF6) Membrane trafficking [BR:pon04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     100449432 (TRAF6) Ubiquitin system [BR:pon04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     100449432 (TRAF6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-C3HC4_3 zf-RING_2 zf-RING_UBOX zf-C3HC4_4 zf-TRAF_2 zf-RING_5 SlyX U-box zf-RING_11 Tropomyosin_1 Spc29 DM ADIP EzrA Dynactin_p22 DUF16 AAA_13 PspA_IM30 UPF0242 FliJ DUF3450 Filament Sina Motif Other DBs NCBI-GeneID:  100449432 NCBI-ProteinID:  XP_002821919 Ensembl:  ENSPPYG00000003350 UniProt:  A0A2J8WFR2 LinkDB All DBs Position 11 AA seq 522 aa AA seqDB search MSLLNCENSCGSSQSESDCCVAMASSCSAATKDDSVGGTASTGNLSSSFMEEIQGYDVEF DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSLIPDSGYISEVRNFQETIH QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV NT seq 1569 nt NT seq  +upstreamnt  +downstreamnt atgagtctgctaaactgtgaaaacagctgtggatccagccagtctgaaagtgactgctgt gtggccatggccagctcctgtagcgctgcaacaaaagatgatagtgtgggtggaactgcc agcacggggaacctctccagctcatttatggaggagatccagggatatgatgtagagttt gacccacccctggaaagcaaatatgaatgccccatctgcctgatggcattacgagaagca gtgcaaacgccatgcggccataggttctgcaaagcctgcatcataaaatcaataagggat gcaggtcacaaatgtccagttgacaatgaaatactgctggaaaatcaactatttccagac aattttgcaaaacgtgagattctttctctgatggtgaagtgtccaaatgaaggttgtttg cacaagatggaactgagacatcttgaggatcatcaagcacattgtgagtttgctcttatg gattgtccccaatgccagcgtcctttccaaaaatttcatattaatattcacattctgaag gattgtccaaggagacaggtttcttgtgacaactgtgctgcatcaatggcatttgaagat aaagagatccatgaccagaactgtcctttggcaaatgtcatctgtgaatactgcaatact atactcatcagagaacagatgcctaatcattatgatctagactgccctacagccccaatt ccatgcacattcagtacttttggttgccatgaaaagatgcagaggaatcacttggcacgc cacctacaagagaacacccagtcacacatgagaatgttggcccaggctgttcatagtttg agccttatacctgactctgggtatatctcagaggtccggaatttccaggaaactattcac cagttagagggtcgccttgtaagacaagaccatcaaatccgggagctgactgctaaaatg gaaactcagagtatgtatgtaagtgagctcaaacgaaccattcgaacccttgaggacaaa gttgctgaaatcgaagcacagcagtgcaatggaatttatatttggaagattggcaacttt ggaatgcatttgaaatgtcaagaagaggagaaacctgttgtgattcatagccctggattc tacactggcaaacccgggtacaaactgtgcatgcgcttgcaccttcagttaccgactgct cagcgctgtgcaaactatatatccctttttgtccacacaatgcaaggagaatatgacagc cacctcccttggcccttccagggtacaatacgccttacaattcttgatcagtctgaagca cctgtaaggcaaaaccacgaagagataatggatgccaaaccagagctgcttgctttccag cgacccacaatcccacggaacccaaaaggctttggctatgtaacttttatgcatctggaa gccctaagacaaagaactttcattaaggatgacacattattagtgcgctgtgaggtctcc acccgctttgacatgggtagccttcggagggagggttttcagccacgaagtactgatgca ggggtatag

Pongo abelii (Sumatran orangutan): 100453867 Help Entry 100453867         CDS       T01416                                  Gene name TRAF5 Definition (RefSeq) TNF receptor-associated factor 5 isoform X2   KO K09849   TNF receptor-associated factor 5 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04064   NF-kappa B signaling pathway pon04217   Necroptosis pon04621   NOD-like receptor signaling pathway pon04657   IL-17 signaling pathway pon04668   TNF signaling pathway pon05163   Human cytomegalovirus infection pon05168   Herpes simplex virus 1 infection pon05169   Epstein-Barr virus infection pon05170   Human immunodeficiency virus 1 infection pon05200   Pathways in cancer pon05203   Viral carcinogenesis pon05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100453867 (TRAF5)    04668 TNF signaling pathway     100453867 (TRAF5)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     100453867 (TRAF5)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     100453867 (TRAF5)    04657 IL-17 signaling pathway     100453867 (TRAF5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100453867 (TRAF5)    05203 Viral carcinogenesis     100453867 (TRAF5)   09162 Cancer: specific types    05222 Small cell lung cancer     100453867 (TRAF5)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100453867 (TRAF5)    05168 Herpes simplex virus 1 infection     100453867 (TRAF5)    05163 Human cytomegalovirus infection     100453867 (TRAF5)    05169 Epstein-Barr virus infection     100453867 (TRAF5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pon04121]     100453867 (TRAF5) Ubiquitin system [BR:pon04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     100453867 (TRAF5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-TRAF zf-C3HC4 zf-C3HC4_2 zf-C3HC4_4 zf-TRAF_2 zf-ACC Spc29 Sina ATG16 zf-RING_6 zf-RING_UBOX zf-RING_2 Acetyltransf_11 DUF4941 BORCS8 Mt_ATP_synt FlaC_arch PHM7_cyt DUF4279 Motif Other DBs NCBI-GeneID:  100453867 NCBI-ProteinID:  XP_002809541 Ensembl:  ENSPPYG00000000244 UniProt:  A0A6D2XMG5 A0A2J8V6G2 LinkDB All DBs Position 1 AA seq 557 aa AA seqDB search MAYSEEHKGMPCGFIRQNSGNSISLDFEPNIEYQFVERLEERYKCAFCHSVLHNPHQTGC GHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKV ILGRYQDHLQQCLFQAVQCSNEKCREPVLRKDLKEHLSAYCQFREEKCLYCKKDVVVINL QNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQE HERSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFG KNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLE NNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREA VDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQ RVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYLKD DTLFLKVAVDLTDLEDL NT seq 1674 nt NT seq  +upstreamnt  +downstreamnt atggcttattcagaagagcataaaggtatgccctgtggtttcatccgccagaattccggc aactccatttccttggactttgagcccaatatagagtaccagtttgtggagcggttggaa gagcgctacaaatgtgccttctgccactcggtgcttcacaacccccaccagacaggatgt gggcaccgcttctgccagcactgcatcctgtccctgagagaattaaacacagtgccaatc tgccctgtagataaggaggtcatcaaatctcaggaggtttttaaagacaattgctgcaaa agagaagtcctcaacttatatgtatattgcagcaatgctcctggatgtaatgccaaggtt attctgggccggtaccaggatcaccttcagcagtgcttatttcaagctgtgcagtgttct aatgagaagtgccgggaaccagtcctacggaaagacctgaaagagcatttgagtgcatac tgtcagtttcgagaggaaaaatgcctttattgcaaaaaggatgtggtagtcatcaatcta cagaatcatgaggaaaacttgtgtcctgaatacccagtattttgtcccaacaattgtgcg aagattattctaaaaactgaggtggatgaacacctggctgtatgtcctgaagctgagcaa gactgtccttttaagcactatggctgtgctgtaacggataaacggaggaacctgcaggaa catgagcgttcagctttacgggagcacatgcgtttggttttggaaaagaatgtccaatta gaagaacagatttctgacttacacaagagcctagaacagaaagaaagtaaaatccagcag ctagcagaaactataaagaaacttgaaaaggagttcaagcagtttgcacagttgtttggc aaaaatggaagcttcctcccaaacatccaggtttttgccagtcacattgacaagtcagct tggctagaagctcaagtgcatcaattattacaaatggttaaccagcaacaaaataaattt gacctgaggcctttgatggaagcagttgatacagtgaaacagaaaattaccctgctagaa aacaatgatcaaagattagctgttttagaagaggaaactaacaaacatgatacccacatt aatattcataaagcacagctgagtaaaaatgaagagcgatttaaactgctggagggtact tgctataatggaaagctcatttggaaggtgacagattacaagatgaagaagagagaggcg gtggatgggcacacagtgtccatcttcagccagtccttctacaccagccgctgtggctac cggctctgtgctagagcatacctgaatggggatgggtctgggaaggggacacacctgtcc ctatactttgtggtcatgcgaggagagtttgactcactgttgcagtggccattcaggcag agggtgaccctgatgcttctggaccagagtggcaaaaagaacattatggagaccttcaag cctgaccccaatagcagcagctttaaaagacctgatggggagatgaacattgcatctggc tgtccccgctttgtggctcattctgttttggagaatgccaagaacgcctaccttaaagat gacactctgttcttgaaagtggccgtggacttaactgacctggaggatctctag

Pongo abelii (Sumatran orangutan): 100458089 Help Entry 100458089         CDS       T01416                                  Gene name TRAF2 Definition (RefSeq) TNF receptor-associated factor 2   KO K03173   TNF receptor-associated factor 2 [EC:2.3.2.27] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04010   MAPK signaling pathway pon04064   NF-kappa B signaling pathway pon04071   Sphingolipid signaling pathway pon04141   Protein processing in endoplasmic reticulum pon04210   Apoptosis pon04217   Necroptosis pon04380   Osteoclast differentiation pon04621   NOD-like receptor signaling pathway pon04622   RIG-I-like receptor signaling pathway pon04657   IL-17 signaling pathway pon04668   TNF signaling pathway pon04920   Adipocytokine signaling pathway pon04932   Non-alcoholic fatty liver disease pon05010   Alzheimer disease pon05014   Amyotrophic lateral sclerosis pon05016   Huntington disease pon05017   Spinocerebellar ataxia pon05022   Pathways of neurodegeneration - multiple diseases pon05132   Salmonella infection pon05135   Yersinia infection pon05160   Hepatitis C pon05163   Human cytomegalovirus infection pon05167   Kaposi sarcoma-associated herpesvirus infection pon05168   Herpes simplex virus 1 infection pon05169   Epstein-Barr virus infection pon05170   Human immunodeficiency virus 1 infection pon05200   Pathways in cancer pon05203   Viral carcinogenesis pon05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:pon00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     100458089 (TRAF2)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100458089 (TRAF2)    04064 NF-kappa B signaling pathway     100458089 (TRAF2)    04668 TNF signaling pathway     100458089 (TRAF2)    04071 Sphingolipid signaling pathway     100458089 (TRAF2)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100458089 (TRAF2)    04217 Necroptosis     100458089 (TRAF2)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     100458089 (TRAF2)    04622 RIG-I-like receptor signaling pathway     100458089 (TRAF2)    04657 IL-17 signaling pathway     100458089 (TRAF2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     100458089 (TRAF2)   09158 Development and regeneration    04380 Osteoclast differentiation     100458089 (TRAF2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100458089 (TRAF2)    05203 Viral carcinogenesis     100458089 (TRAF2)   09162 Cancer: specific types    05222 Small cell lung cancer     100458089 (TRAF2)   09164 Neurodegenerative disease    05010 Alzheimer disease     100458089 (TRAF2)    05014 Amyotrophic lateral sclerosis     100458089 (TRAF2)    05016 Huntington disease     100458089 (TRAF2)    05017 Spinocerebellar ataxia     100458089 (TRAF2)    05022 Pathways of neurodegeneration - multiple diseases     100458089 (TRAF2)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     100458089 (TRAF2)   09171 Infectious disease: bacterial    05132 Salmonella infection     100458089 (TRAF2)    05135 Yersinia infection     100458089 (TRAF2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100458089 (TRAF2)    05160 Hepatitis C     100458089 (TRAF2)    05168 Herpes simplex virus 1 infection     100458089 (TRAF2)    05163 Human cytomegalovirus infection     100458089 (TRAF2)    05167 Kaposi sarcoma-associated herpesvirus infection     100458089 (TRAF2)    05169 Epstein-Barr virus infection     100458089 (TRAF2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:pon03019]     100458089 (TRAF2)    04121 Ubiquitin system [BR:pon04121]     100458089 (TRAF2) Enzymes [BR:pon01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      100458089 (TRAF2) Messenger RNA biogenesis [BR:pon03019]  Eukaryotic type   mRNA surveillance and transport factors    mRNA cycle factors     Stress granule specific factors      100458089 (TRAF2) Ubiquitin system [BR:pon04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     100458089 (TRAF2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF_BIRC3_bd zf-TRAF zf-C3HC4 zf-C3HC4_2 zf-RING_6 zf-C3HC4_4 MATH SlyX Motif Other DBs NCBI-GeneID:  100458089 NCBI-ProteinID:  XP_003777545 Ensembl:  ENSPPYG00000019790 UniProt:  A0A2J8RMN7 LinkDB All DBs Position 9 AA seq 501 aa AA seqDB search MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEAQWL REHLAMLLSSVLEAKPLSGDQSHAGSELLQRCESLENKTATFENIVCVLNREVERVAMTA EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD FARKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA KNSYVRDDAIFIKAIVDLTGL NT seq 1506 nt NT seq  +upstreamnt  +downstreamnt atggctgcagctagcgtgaccccccctggctccctggagttgctacagcccggcttctcc aagaccctcctggggaccaagctggaagccaagtacctgtgctccgcctgcagaaacgtc ctccgcaggcccttccaggcgcagtgtggccaccggtactgctccttctgcttggccagc atcctcagctctgggcctcagaactgtgctgcctgtgttcacgagggcatatatgaagaa ggcatttctattttagaaagcagttcggccttcccagataatgctgcccgcagggaggtg gagagcctgccggccgtctgtcccagtgatgggtgcacctggaaggggaccctgaaagaa tacgagagctgccacgaaggccgctgcccactcatgctgaccgaatgtcccgcgtgcaaa ggcctggtccgccttggtgaaaaggagcgccacctggagcacgagtgcccagagagaagc ctgagctgccggcattgccgggcgccctgctgcggagcggacgtgaaggcgcaccacgag gtctgccctaagttccccttgacttgtgacggctgcggcaagaagaagatcccccgggag aagtttcaggaccacgtcaagacttgtggcaagtgtcgagtcccttgcagattccacgcc atcggctgcctcgagacggtagagggtgagaaacagcaggagcatgaggcgcagtggctg cgggagcacctggccatgctactgagctcggtgctggaggcaaagcccctctcgggagac cagagccacgcggggtcagagctcctgcagaggtgcgagagcctggagaacaagacggcc acttttgagaacattgtctgcgtcctgaaccgggaggtggagagggtggccatgactgcc gaggcctgcagccggcagcaccggctggaccaagacaagattgaagccctgagtagcaag gtgcagcagctagagaggagcatcggcctcaaggacctggcgatggccgacctggagcag aaggtcttggagatggaggcatccacctacgatggggtcttcatctggaagatctcagac tttgccaggaagcgccaggaagctgtggctggccgcacacccgccatcttctccccagcc ttctacaccagcaggtacggctacaagatgtgtctgcgtatctacctgaatggcgacggc accgggcgaggaacacacctgtccctcttctttgtggtgatgaagggcccgaatgacgcc ctgctgcggtggcccttcaaccagaaggtgaccttaatgctgcttgaccagaataaccgg gagcacgtgattgacgccttcaggccggatgtgacctcgtcctcttttcagaggccagtc aacgacatgaacatcgcaagcggctgccctctcttctgccccgtctccaagatggaggcc aagaattcctacgtgcgggacgatgccatcttcatcaaggccattgtggacctgacaggg ctctaa

Pongo abelii (Sumatran orangutan): 100460079 Help Entry 100460079         CDS       T01416                                  Gene name TRAF3 Definition (RefSeq) TNF receptor-associated factor 3 isoform X1   KO K03174   TNF receptor-associated factor 3 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04064   NF-kappa B signaling pathway pon04620   Toll-like receptor signaling pathway pon04621   NOD-like receptor signaling pathway pon04622   RIG-I-like receptor signaling pathway pon04657   IL-17 signaling pathway pon04668   TNF signaling pathway pon05160   Hepatitis C pon05161   Hepatitis B pon05162   Measles pon05164   Influenza A pon05165   Human papillomavirus infection pon05167   Kaposi sarcoma-associated herpesvirus infection pon05168   Herpes simplex virus 1 infection pon05169   Epstein-Barr virus infection pon05171   Coronavirus disease - COVID-19 pon05200   Pathways in cancer pon05203   Viral carcinogenesis pon05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100460079 (TRAF3)    04668 TNF signaling pathway     100460079 (TRAF3)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100460079 (TRAF3)    04621 NOD-like receptor signaling pathway     100460079 (TRAF3)    04622 RIG-I-like receptor signaling pathway     100460079 (TRAF3)    04657 IL-17 signaling pathway     100460079 (TRAF3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100460079 (TRAF3)    05203 Viral carcinogenesis     100460079 (TRAF3)   09162 Cancer: specific types    05222 Small cell lung cancer     100460079 (TRAF3)   09172 Infectious disease: viral    05161 Hepatitis B     100460079 (TRAF3)    05160 Hepatitis C     100460079 (TRAF3)    05171 Coronavirus disease - COVID-19     100460079 (TRAF3)    05164 Influenza A     100460079 (TRAF3)    05162 Measles     100460079 (TRAF3)    05168 Herpes simplex virus 1 infection     100460079 (TRAF3)    05167 Kaposi sarcoma-associated herpesvirus infection     100460079 (TRAF3)    05169 Epstein-Barr virus infection     100460079 (TRAF3)    05165 Human papillomavirus infection     100460079 (TRAF3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-TRAF zf-C3HC4 ATG16 Crescentin zf-C3HC4_2 MPS2 Tropomyosin_1 Spc7 Cast Spc29 zf-RING_4 KxDL T3SSipB FliJ BLOC1_2 DUF1664 Exonuc_VII_L Fib_alpha GAS SPATA24 DUF3450 Motif Other DBs NCBI-GeneID:  100460079 NCBI-ProteinID:  XP_024087683 Ensembl:  ENSPPYG00000006162 LinkDB All DBs Position 14 AA seq 568 aa AA seqDB search MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCRLVL CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE SRGCAEQLTLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ TVLENGTYIKDDTIFIKVIVDTSDLPDP NT seq 1707 nt NT seq  +upstreamnt  +downstreamnt atggagtcgagtaaaaagatggactctcctggcgcgctgcagactaacccaccgctaaag ctgcacactgaccgtagtgctgggacgccagtttttgtccctgaacaaggaggttacaag gaaaagtttgtgaagacagtggaggacaagtacaagtgtgagaagtgccgcctggtgctg tgcagcccaaagcagaccgagtgtgggcaccgcttctgcgagagctgcatggccgccctg ctgagctcttcaagtccaaaatgtacagcgtgtcaagagagcatcgttaaagataaggtg tttaaggataattgctgcaagagagaaattctggctcttcagatctattgtcggaatgaa agcagaggttgtgcagagcagttaacgctgggacatctgctggtgcatttaaaaaatgat tgccattttgaagagcttccatgtgtgcgtcctgactgcaaagaaaaggtcttgaggaaa gacctgcgagaccacgtggagaaggcgtgtaaataccgggaagccacgtgcagccactgc aagagtcaggttccgatgatcgcgctgcagaaacacgaagacaccgactgtccctgcgtg gtggtatcctgccctcacaagtgcagcgtccagactctcctgaggagcgagttgagtgca cacttgtcagagtgtgtcaatgcccccagcacctgtagttttaagcgctatggctgcgtt tttcaggggacaaaccagcagatcaaggcccacgaggccagctccgccgtgcagcacgtc aacctgctgaaggagtggagcaactcgctcgaaaagaaggtttccttgttgcagaatgaa agtgtagaaaaaaacaagagcatacaaagtttgcacaatcagatatgtagctttgaaatt gaaattgagagacaaaaggaaatgcttcgaaataatgaatcaaaaatccttcatttacag cgagtgatagacagccaagcagagaaactgaaggagctcgacaaggagatccggcccttc cggcagaactgggaggaagcagacagcatgaagagcagcgtggagtccctccagaaccgc gtgactgagctggagagcgtggacaagagcgcggggcaagtggctcggaacacaggcctg ctggagtcccagctgagccggcatgaccagatgctgagtgtgcacgacatccgcctggcc gacatggacctgcgcttccaggtcctggagaccgccagctacaatggagtgctcatctgg aagattcgcgactacaagcggcggaagcaggaggccgtcatggggaagaccctgtccctt tacagccagcctttctacaccggctactttggctataagatgtgtgccagggtctacctg aacggggacgggatggggaaggggacgcacttgtcgctgttttttgtcatcatgcgtggg gaatacgacgccctgcttccttggccgtttaagcagaaagtgacactcatgctgatggat caggggtcctctcgacgccatttgggagatgcgttcaagcccgaccccaacagcagcagc ttcaagaagcccactggagagatgaatatcgcctctggctgcccagtctttgtggcccaa actgttctagaaaatgggacatatattaaagatgatacaatttttattaaagtcatagtg gatacttcggatctgcccgatccctga

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