KEGG   Pongo abelii (Sumatran orangutan): 100173225
Entry
100173225         CDS       T01416                                 

Gene name
SHC1
Definition
(RefSeq) SHC-transforming protein 1
  KO
K06279  SHC-transforming protein 1
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon01522  Endocrine resistance
pon04012  ErbB signaling pathway
pon04014  Ras signaling pathway
pon04062  Chemokine signaling pathway
pon04072  Phospholipase D signaling pathway
pon04510  Focal adhesion
pon04650  Natural killer cell mediated cytotoxicity
pon04722  Neurotrophin signaling pathway
pon04910  Insulin signaling pathway
pon04915  Estrogen signaling pathway
pon04917  Prolactin signaling pathway
pon04926  Relaxin signaling pathway
pon04935  Growth hormone synthesis, secretion and action
pon05034  Alcoholism
pon05100  Bacterial invasion of epithelial cells
pon05206  MicroRNAs in cancer
pon05214  Glioma
pon05220  Chronic myeloid leukemia
pon05224  Breast cancer
pon05225  Hepatocellular carcinoma
pon05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100173225 (SHC1)
   04014 Ras signaling pathway
    100173225 (SHC1)
   04072 Phospholipase D signaling pathway
    100173225 (SHC1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100173225 (SHC1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100173225 (SHC1)
   04062 Chemokine signaling pathway
    100173225 (SHC1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100173225 (SHC1)
   04915 Estrogen signaling pathway
    100173225 (SHC1)
   04917 Prolactin signaling pathway
    100173225 (SHC1)
   04926 Relaxin signaling pathway
    100173225 (SHC1)
   04935 Growth hormone synthesis, secretion and action
    100173225 (SHC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100173225 (SHC1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100173225 (SHC1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100173225 (SHC1)
   05226 Gastric cancer
    100173225 (SHC1)
   05214 Glioma
    100173225 (SHC1)
   05220 Chronic myeloid leukemia
    100173225 (SHC1)
   05224 Breast cancer
    100173225 (SHC1)
  09165 Substance dependence
   05034 Alcoholism
    100173225 (SHC1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100173225 (SHC1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100173225 (SHC1)
   01522 Endocrine resistance
    100173225 (SHC1)
SSDB
Motif
Pfam: PID SH2 Delta_lysin
Other DBs
NCBI-GeneID: 100173225
NCBI-ProteinID: NP_001126253
Ensembl: ENSPPYG00000000769
UniProt: Q5R7W7
LinkDB
Position
1
AA seq 583 aa
MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLRDMNKLSGGGGR
RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL
GGVVDMRLREGAAPGAARSTAPSAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRE
LFDDPSYVNVQNLDKARQAVGGAGPPNPAVNGSAPRDLFDMRPFEDALRVPPPPQSVSMA
EQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEG
VVRTKDHRFESVSHLIGYHMDNHLPIISAGSELCLQQPVERKL
NT seq 1752 nt   +upstreamnt  +downstreamnt
atggatctcctgccccccaagcccaagtacaatccactccggaatgagtctctgtcatcg
ctggaggaaggggcttctgggtccacccccccggaggagctgccttctccatcagcttca
tccctggggcccatcctgcctcctctgcctggggacgatagtcccactaccctgtgctcc
ttcttcccccggatgagcaacctgaggctggccaacccggctggggggcgcccagggtct
aagggggagccaggaagggcagccgatgatggggaggggatcgtaggggcagccatgcca
gactcaggccccctacccctcctccgggacatgaacaagctgagtggaggcggcgggcgc
aggactcgggtggaagggggccagctggggggcgaggagtggacccgccacgggagcttt
gtcaataagcccacgcggggctggctgcatcccaacgacaaagtcatgggacccggggtt
tcctacttggttcggtacatgggctgtgtggaggtccttcagtcaatgcgtgccctggac
ttcaacacccggactcaggtcaccagggaggccatcagtctggtgtgtgaggctgtgccg
ggtgctaagggggcaacgaggaggagaaagccctgtagccgcccgctcagctctatcctg
gggaggagtaacctgaaatttgctggaatgccaatcactctcaccgtctccaccagcagc
ctcaacctcatggccgcagactgcaaacagatcatcgccaaccaccacatgcaatctatc
tcatttgcatccggcggggatccggacacagccgagtatgtcgcctacgttgccaaagac
cctgtgaatcagagagcctgccacattctggagtgtcccgaagggcttgcccaggatgtc
atcagcaccattggccaggccttcgagttgcgcttcaaacaatacctcaggaacccaccc
aaactggtcacccctcatgacaggatggctggctttgatggctcagcatgggatgaggag
gaggaagagccacctgaccatcagtactataatgacttcccggggaaggaaccccccctg
gggggggtggtagacatgaggcttcgggaaggagccgctccaggggctgctcgatccacc
gcacccagtgcccagacccccagccacttgggagctacactgcctgtaggacagcctgtt
gggggagatccagaagtccgcaaacagatgccacctccaccaccctgtccaggtagagag
ctctttgatgatccctcctatgtcaacgtccagaacctagacaaggcccggcaagcagtg
ggtggtgctgggccccctaatcctgctgtcaatggcagtgcaccccgggacctgtttgac
atgaggcccttcgaagatgctcttcgggtgcctccacctccccagtcggtgtccatggct
gagcagctccgaggggagccctggttccacgggaagctgagccggcgggaggctgaggca
ctgctgcagctcaacggggacttcctggtgcgggagagcacgaccacacctggccagtat
gtgctcactggcttgcagagtgggcagcccaagcatttgctactggtggaccctgagggt
gtggttcggactaaggatcaccgctttgagagtgtcagtcaccttatcggctaccacatg
gacaatcacttgcccatcatctctgcgggcagcgaactgtgtctacagcaacctgtggag
cggaaactgtga

KEGG   Pongo abelii (Sumatran orangutan): 100431574
Entry
100431574         CDS       T01416                                 

Gene name
SHC4
Definition
(RefSeq) SHC-transforming protein 4
  KO
K17449  SHC-transforming protein 4
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon01522  Endocrine resistance
pon04012  ErbB signaling pathway
pon04014  Ras signaling pathway
pon04062  Chemokine signaling pathway
pon04072  Phospholipase D signaling pathway
pon04510  Focal adhesion
pon04650  Natural killer cell mediated cytotoxicity
pon04722  Neurotrophin signaling pathway
pon04910  Insulin signaling pathway
pon04915  Estrogen signaling pathway
pon04917  Prolactin signaling pathway
pon04926  Relaxin signaling pathway
pon04935  Growth hormone synthesis, secretion and action
pon05034  Alcoholism
pon05100  Bacterial invasion of epithelial cells
pon05206  MicroRNAs in cancer
pon05214  Glioma
pon05220  Chronic myeloid leukemia
pon05224  Breast cancer
pon05225  Hepatocellular carcinoma
pon05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100431574 (SHC4)
   04014 Ras signaling pathway
    100431574 (SHC4)
   04072 Phospholipase D signaling pathway
    100431574 (SHC4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100431574 (SHC4)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100431574 (SHC4)
   04062 Chemokine signaling pathway
    100431574 (SHC4)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100431574 (SHC4)
   04915 Estrogen signaling pathway
    100431574 (SHC4)
   04917 Prolactin signaling pathway
    100431574 (SHC4)
   04926 Relaxin signaling pathway
    100431574 (SHC4)
   04935 Growth hormone synthesis, secretion and action
    100431574 (SHC4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100431574 (SHC4)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100431574 (SHC4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100431574 (SHC4)
   05226 Gastric cancer
    100431574 (SHC4)
   05214 Glioma
    100431574 (SHC4)
   05220 Chronic myeloid leukemia
    100431574 (SHC4)
   05224 Breast cancer
    100431574 (SHC4)
  09165 Substance dependence
   05034 Alcoholism
    100431574 (SHC4)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100431574 (SHC4)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100431574 (SHC4)
   01522 Endocrine resistance
    100431574 (SHC4)
SSDB
Motif
Pfam: PID SH2 Delta_lysin
Other DBs
NCBI-GeneID: 100431574
NCBI-ProteinID: XP_024088170
Ensembl: ENSPPYG00000006457
LinkDB
Position
15
AA seq 630 aa
MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLEEGSSGGSVGNKGSPQLPH
PALAPHLPAEDATLPSQESPTPLCTLIPRMASMKLANPVTLLSLKNFCLGTKEVPRLKLQ
ESRDPGSSGPSSPETSRSRSGTAPPPQQDLVGHRATALTADSCPLPGPGEPPLRSRQDRH
FLQHLLGKGMNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRK
PPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDT
TDYVAYVAKDPVNQRACHILECHNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEV
HIDSHAEEREDHEYYNEIPGKQPPVGGVSDMRIKVQATEQMAYCPIRCEKLCYLPGNSKC
SSVYENCLEQSRAIGNVHPRGVQSERDTSLLKHTCRVDLFDDPCYINTQALQSTLGSAGN
QSSAQPLGSPWHCGKAPETVQPGATAQPASSHSLPHIKQQLWSEECYHGKLSRKAAESLL
VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDN
SLPIISSGSEVSLKQPVRKENNPALLHSNK
NT seq 1893 nt   +upstreamnt  +downstreamnt
atgcgagaacgcggccaggacagcctggcaggactcgtgctgtatgtaggactcttcggg
caccccggcatgctgcacagggccaagtacagccgctttcggaacgagtcgatcacgtcc
ttggaagaaggtagctccggaggctcggtcgggaacaagggctcgccgcagcttccccac
cccgccctggcacctcacctgccggctgaagatgccaccttgccgtcgcaggagagcccc
accccattgtgcaccttgataccccgcatggcaagcatgaagctggccaacccggtcact
ttgctgagtctgaaaaacttttgcctgggtaccaaagaggtgcctcggctgaagctccag
gaaagcagggacccaggttccagcggcccctcttccccagaaaccagtcgaagtaggtcc
ggaactgcacctccaccgcagcaggacctggtgggccacagggcaaccgccctaaccgct
gattcgtgcccgcttcctggccctggggagccaccccttaggagcaggcaggacaggcac
tttctacagcacctgttggggaagggcatgaactactgtgtgaggtacatgggctgtatt
gaagtgctgcaatcaatgagatcactggattttggaatgagaacccaagttacaagggaa
gcaataagtcgcctgtgtgaagctgtccccggggcaaatggagccattaaaaagcgaaag
cctccagttaagttcctatcaacagttcttggcaaaagtaatcttcagttttcaggaatg
aatataaaactgaccatctcaacatgcagtctcacattgatgaatcttgacaaccaacag
attattgcaaatcatcatatgcagtctatttcatttgcctctggaggggatcctgatact
acagactatgttgcctacgtagctaaagatccagttaatcaacgagcctgtcacatattg
gaatgccacaatggaatggcccaagacgtcataagtaccatagggcaggcttttgaactc
cggtttaaacagtacttgaaaaatccttctttgaatacttcttgtgaaagtgaggaggtg
catattgatagccatgctgaggagagagaagatcatgaatattacaatgaaattccaggg
aagcagccaccagtaggtggtgtttcagatatgcggatcaaagttcaagccacggaacaa
atggcttactgccccatacggtgtgaaaagttgtgctatttgcctggaaactccaagtgc
agcagtgtatatgagaactgtttagaacaaagcagggcaataggtaatgtccatccaaga
ggggtgcagtccgagcgagatacttcattattgaagcacacgtgccgagtggatctcttc
gatgacccctgctacattaatacgcaggctcttcaaagtacacttggctctgctggaaat
caaagctcagcccaaccactggggagcccatggcactgcggaaaggcaccagaaactgtt
cagccgggtgccacagcccagcctgccagctcacattctttgccacacattaagcagcag
ctgtggagtgaagaatgctatcatggcaagctgagcaggaaggcggcagagagcctcttg
gtaaaggatggggactttttggttcgagagagtgcaacatcccctggccaatatgtgctg
agtggactacagggaggccaagcaaaacatcttcttctggtggatcctgaaggcaaggtg
aggaccaaggatcatgtatttgataatgtcggccaccttatcagataccatatggataac
agtttgccaatcatctcctctggaagcgaagtaagccttaaacaaccagtgagaaaagag
aataatccagcacttttgcattccaacaaatga

KEGG   Pongo abelii (Sumatran orangutan): 100445042
Entry
100445042         CDS       T01416                                 

Gene name
SHC2
Definition
(RefSeq) SHC-transforming protein 2
  KO
K17447  SHC-transforming protein 2
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon01522  Endocrine resistance
pon04012  ErbB signaling pathway
pon04014  Ras signaling pathway
pon04062  Chemokine signaling pathway
pon04072  Phospholipase D signaling pathway
pon04370  VEGF signaling pathway
pon04510  Focal adhesion
pon04650  Natural killer cell mediated cytotoxicity
pon04722  Neurotrophin signaling pathway
pon04910  Insulin signaling pathway
pon04915  Estrogen signaling pathway
pon04917  Prolactin signaling pathway
pon04926  Relaxin signaling pathway
pon04935  Growth hormone synthesis, secretion and action
pon05034  Alcoholism
pon05100  Bacterial invasion of epithelial cells
pon05214  Glioma
pon05220  Chronic myeloid leukemia
pon05224  Breast cancer
pon05225  Hepatocellular carcinoma
pon05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100445042 (SHC2)
   04014 Ras signaling pathway
    100445042 (SHC2)
   04370 VEGF signaling pathway
    100445042 (SHC2)
   04072 Phospholipase D signaling pathway
    100445042 (SHC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100445042 (SHC2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100445042 (SHC2)
   04062 Chemokine signaling pathway
    100445042 (SHC2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100445042 (SHC2)
   04915 Estrogen signaling pathway
    100445042 (SHC2)
   04917 Prolactin signaling pathway
    100445042 (SHC2)
   04926 Relaxin signaling pathway
    100445042 (SHC2)
   04935 Growth hormone synthesis, secretion and action
    100445042 (SHC2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100445042 (SHC2)
 09160 Human Diseases
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100445042 (SHC2)
   05226 Gastric cancer
    100445042 (SHC2)
   05214 Glioma
    100445042 (SHC2)
   05220 Chronic myeloid leukemia
    100445042 (SHC2)
   05224 Breast cancer
    100445042 (SHC2)
  09165 Substance dependence
   05034 Alcoholism
    100445042 (SHC2)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100445042 (SHC2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100445042 (SHC2)
   01522 Endocrine resistance
    100445042 (SHC2)
SSDB
Motif
Pfam: PID SH2
Other DBs
NCBI-GeneID: 100445042
NCBI-ProteinID: XP_024092984
LinkDB
Position
19
AA seq 582 aa
MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGA
DPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGARGPRGARGAAGSGDAA
AAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTR
EAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQ
VIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFEL
RFKQYLHSPPKVVLPPERLAGLEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALT
QPCALTALDQGPSPSLRDARSLPWDVGSTGTALPGDGYVQADARGPPDHEEHLYVNTQGL
DAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPPPLEDQWPSPPTRRAPVAPTEE
QLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGV
VRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP
NT seq 1749 nt   +upstreamnt  +downstreamnt
atgacgcagggtccgggtgggcgcgcgcccccggcgccccccgcgccccccgagcccgag
gcgcccaccaccttctgcgcgttgctgccccgaatgccgcagtggaagttcgcggccccg
ggcggcttcctgggccgcggcccggcggcggcgcgggcggctggggcctcggggggcgcg
gacccccagcccgagccggcgggcccggggggcgtcccggcgctggcggccgccgtccta
ggcgcctgcgagccccgctgcgccgcgccctgtcccctgcccgcgctcagccgctgtcgg
ggcgcgggggcgcggggaccgcggggcgcgcgtggggcggcagggtctggggacgccgcc
gccgccgccgagtggatccggaagggcagcttcatccacaaacccgcgcacggctggtta
caccccgacgccagggtcctggggcccggggtctcctacgtcgtgcggtacatgggctgc
atcgaggttctccgctccatgcgctccctggactttaacacgcgcacgcaggtgaccagg
gaagccatcaaccggctccatgaggccgtgcctggcgtccggggatcctggaagaaaaag
gcccccaacaaggccctggcgtccgtcctgggcaagagcaaccttcgctttgccggcatg
agcatttccatccacatctccaccgatggcctcagcctctctgtgcctgccacgcgccag
gtcatcgccaaccaccacatgccgtccatctccttcgcatcaggcggagacacggacatg
acggattacgtggcctacgtcgccaaggaccccatcaaccagagagcctgccacatcctg
gagtgctgtgagggcctggcgcagagcatcatcagcaccgtgggccaagccttcgagctg
cgcttcaagcagtacctgcacagcccacccaaggtggtgctgcccccagaaaggctggcg
gggctggaggagtcggcctggggggacgaggaggactctttggagcacaattactacaac
agcatcccagggaaggaaccgccgctgggcgggctagtggactccaggctggccctgaca
cagccctgcgccctcacggccctcgaccagggcccatctccttctctaagagatgcccgc
agcctgccatgggacgtggggtccactggtacagctctaccgggggacggctacgtgcag
gcggacgcccggggccccccggaccacgaggagcacctgtatgtcaacacccagggtctg
gacgcccccgagccggaggacagccccaaaaaggatctgtttgacatgcgaccctttgag
gatgccctgaagttgcatgagtgctcagtggcggcaggcgtgacagcagccccccctccc
ttggaggaccagtggcccagccctcctacccgccgagcccctgtggcccccacggaggaa
cagctgcgtcaggagccctggtaccatggccggatgagccgtcgggcggcagagaggatg
cttcgagctgacggggacttcctcgtgcgagacagcgtcaccaaccccgggcagtatgtc
ctcaccggcatgcacgccgggcagcccaagcacctgctgctcgtggaccccgagggtgtg
gttcggacgaaggacgtgctgtttgagagcatcagccacctgatcgaccaccacctgcag
aacgggcagcccatcgtggccgccgagagtgagctgcacctgcgcggcgtggtctcacgg
gagccctga

KEGG   Pongo abelii (Sumatran orangutan): 100462011
Entry
100462011         CDS       T01416                                 

Gene name
SHC3
Definition
(RefSeq) SHC-transforming protein 3
  KO
K17448  SHC-transforming protein 3
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon01522  Endocrine resistance
pon04012  ErbB signaling pathway
pon04014  Ras signaling pathway
pon04062  Chemokine signaling pathway
pon04072  Phospholipase D signaling pathway
pon04510  Focal adhesion
pon04650  Natural killer cell mediated cytotoxicity
pon04722  Neurotrophin signaling pathway
pon04910  Insulin signaling pathway
pon04915  Estrogen signaling pathway
pon04917  Prolactin signaling pathway
pon04926  Relaxin signaling pathway
pon04935  Growth hormone synthesis, secretion and action
pon05034  Alcoholism
pon05100  Bacterial invasion of epithelial cells
pon05214  Glioma
pon05220  Chronic myeloid leukemia
pon05224  Breast cancer
pon05225  Hepatocellular carcinoma
pon05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100462011 (SHC3)
   04014 Ras signaling pathway
    100462011 (SHC3)
   04072 Phospholipase D signaling pathway
    100462011 (SHC3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100462011 (SHC3)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100462011 (SHC3)
   04062 Chemokine signaling pathway
    100462011 (SHC3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100462011 (SHC3)
   04915 Estrogen signaling pathway
    100462011 (SHC3)
   04917 Prolactin signaling pathway
    100462011 (SHC3)
   04926 Relaxin signaling pathway
    100462011 (SHC3)
   04935 Growth hormone synthesis, secretion and action
    100462011 (SHC3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100462011 (SHC3)
 09160 Human Diseases
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100462011 (SHC3)
   05226 Gastric cancer
    100462011 (SHC3)
   05214 Glioma
    100462011 (SHC3)
   05220 Chronic myeloid leukemia
    100462011 (SHC3)
   05224 Breast cancer
    100462011 (SHC3)
  09165 Substance dependence
   05034 Alcoholism
    100462011 (SHC3)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100462011 (SHC3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100462011 (SHC3)
   01522 Endocrine resistance
    100462011 (SHC3)
SSDB
Motif
Pfam: PID SH2
Other DBs
NCBI-GeneID: 100462011
NCBI-ProteinID: XP_009242883
Ensembl: ENSPPYG00000019358
LinkDB
Position
9
AA seq 594 aa
MLPRTKYNRFRNDSVTSVDDLLHSLSVSGGGGKVSAARATPAAAPYLVSGEALRKAPDDG
PGSLGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGSAPSAPRAPA
MSAARKGRPGDEPLPRPPRGGPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQI
TREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD
SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA
FELRFKQYLQCPTKIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPPPGGFLDTRL
KPRPHAPDTAQFAGKEQTYYQGRHLGDTFGEDWQQTPLRQGSLDIYSTPEGKLHVAPTGE
APTYVNTQQIPPQAWPAAVSSAESSPRKDLFDMKPFEDALKNQPLGPVLSKAASVECISP
VSPRAPDAKMLEELQAETWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQ
AKHLLLVDPEGTIRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPVERKQ
NT seq 1785 nt   +upstreamnt  +downstreamnt
atgcttccacgcaccaagtacaaccgcttcaggaatgactcggtgacatcggtcgatgac
cttctccacagcctgtcggtgagcggcggcggaggcaaggtttcggcggcgcgcgcgacc
ccggcggcggctccctacttggtgtccggcgaggcgctgcgcaaggcgcccgacgatggg
cccggcagcctgggccacctgctccacaaggtgtcccacctgaaactctccagctcgggc
ctccgcggcctgtcgtcggccgcccgggagcgggcgggcgcgcggctctctggcagctgc
agcgcgcccagcctggctgccccggacggcagcgcgccctcggcgccccgcgccccggcc
atgagcgccgccaggaagggccggcccggcgacgagccgttgcccaggccccctcgggga
gggccgcacgccagcgaccaggtgctggggcccggagtcacctacgtggtcaagtacttg
gggtgcattgaagttctgcgctcaatgaggtctcttgacttcagtacaagaacacaaatt
accagggaagccatcagccgtgtctgtgaagctgtgcctggtgccaagggagccttcaag
aagagaaagcctccaagcaaaatgctgtccagcatcttgggaaagagcaacctccagttt
gcgggaatgagcatctctctgaccatctccacggccagtctgaacctgcgaactccggac
tccaaacagatcatagcgaatcaccacatgcggtccatctccttcgcctctgggggagac
ccggacacaactgactatgttgcatatgtggctaaggaccctgttaatcgcagagcttgt
cacattttggaatgctgtgatgggctggcccaggatgtcattggctccatcggacaagcc
tttgagctccggtttaagcaatatttacagtgtcctaccaagattcccgctctccatgat
cgaatgcagagtctggatgagccatggacggaagaggagggagatggctcagaccacccg
tactacaacagcatcccaagcaagatgcctcctccagggggctttcttgatactagactg
aaacccagaccccatgctcctgacacagcccagtttgcaggaaaagagcagacttattac
cagggaagacacttaggagacacctttggtgaagactggcagcaaacacctttaaggcaa
gggtccttggacatctacagcacgccagaagggaaactgcacgtggcccccacgggagaa
gcacccacctacgtcaacactcagcagatcccaccacaggcctggccggctgcggtcagc
agtgccgagagcagcccgaggaaagacctctttgacatgaaaccttttgaagatgctctc
aagaaccagcccctggggcccgtgttaagcaaggcagcctccgtggagtgcatcagccct
gtgtcacccagagccccagatgccaagatgctggaggaactgcaagccgagacttggtac
caaggagagatgagcaggaaggaggcagaggggctgctggagaaagacggagacttcctg
gtcaggaagagcaccaccaacccaggctcttttgtcctcacgggcatgcacaatggccag
gccaagcacctgctgctcgtggacccagaaggcacgatccggacgaaggacagagtcttt
gacagtatcagccacctcatcaaccaccacctagagagcagcctgcccattgtctctgca
gggagtgagctgtgtctccagcagccagtagagaggaagcagtga

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