| Entry |
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| Gene name |
ABCC1
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| Definition |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
pon Pongo abelii (Sumatran orangutan)
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| Pathway |
| pon04977 | Vitamin digestion and absorption |
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| Brite |
KEGG Orthology (KO) [BR:pon00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
100431822 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
100431822 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
100431822 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100431822 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100431822 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:pon02000]
100431822 (ABCC1)
Enzymes [BR:pon01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
100431822 (ABCC1)
Transporters [BR:pon02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
100431822 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
16
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| AA seq |
703 aa
MSYLPQVDIIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDPEENGVTGISG
PGKEAKQMENGMLVMDSAGKQLQRQLSSSSSYSGDISRQHNSTAELQKAGAKKEETWKLM
EADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGT
QEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASHYLHVDLLHSILRSPMSFFERTP
SGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFF
VQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKA
YYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLV
RMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDF
VLKHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAKGEIIIDGINIAKIGLHDLRF
KITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGE
NLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRL
NTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV |
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| NT seq |
2112 nt +upstreamnt +downstreamnt
atgagctacttgccgcaggtggacatcatcattgtcatgagtggcggcaagatctctgag
atgggctcctaccaggagctgctggcccgagacggcgccttcgctgagttcctgcgtacc
tatgccagcacagagcaggagcaggacccagaggagaacggggtcacgggcatcagcggt
ccagggaaggaagcaaagcaaatggagaatggcatgctggtgatggacagtgcagggaag
caactgcagagacagctcagcagctcctcctcctatagcggggacatcagcaggcagcac
aacagcaccgcagaactgcagaaagctggggccaagaaggaggagacctggaagctgatg
gaggctgacaaggcgcagacagggcaggtcaagctttccgtgtactgggactacatgaag
gccatcggactcttcatctcctttctcagcatcttccttttcatgtgtaaccatgtgtct
gcgctggcttccaactattggctcagcctctggactgatgaccccatcgtcaacgggacc
caggagcacacgaaagtccggctgagcgtctatggagccctgggcatttcacaagggatc
gccgtgtttggctactccatggccgtgtccatcggggggatcttggcttcccactatctg
catgtggatctgctgcacagcatcctgcgatcacccatgagcttctttgagcggaccccc
agtgggaacctggtgaaccgcttctccaaggagctggacacagtggactccatgatcccg
gaggtcatcaagatgttcatgggctccctgttcaacgtcatcggtgcctgcattgttatc
ctgctggccacgcccatcgccgcaatcatcatcccgcccctcggcctcatctacttcttc
gtccagaggttctacgtggcctcctctcggcagctgaagcgcctcgagtcggtcagccgc
tccccggtctattcccatttcaacgagaccttgctgggggtcagcgtcattcgagccttc
gaggagcaggagcgcttcatccaccagagtgacctgaaggtggacgagaaccagaaggcc
tattaccccagcatcgtggccaacaggtggctggccgtgcggctggagtgtgtgggcaac
tgcatcgttctgtttgctgccctgttcgcggtgatctccaggcacagcctcagtgctggc
ttggtgggcctctcagtgtcttactcattgcaggtcaccacatacttgaactggctggtt
cggatgtcatctgaaatggaaaccaacattgtggctgtggagagactcaaggagtattca
gagactgagaaggaggcgccctggcaaatccaggagacagctccacccagcagctggccc
caggtgggccgagtggaattccggaactactgcctgcgctaccgagaggacctggacttt
gttctcaagcacatcaatgtcaccatcaatgggggagaaaaggtcggcatcgtggggcgg
acgggagctgggaagtcgtccctgaccctgggcttatttcggatcaacgagtctgccaaa
ggagagatcatcatcgatggcatcaacatcgccaagatcggcctgcacgacctccgcttc
aagatcaccatcatcccccaggaccctgttttgttttcgggttccctccgcatgaacctg
gacccattcagccagtactcggacgaagaagtctggacgtccctggagctggcccacctg
aaggacttcgtgtcggcccttcctgacaagctggaccacgagtgtgcagaaggcggggag
aacctcagtgttgggcagcgccagcttgtgtgcctagcccgggcactgctgaggaagaca
aagatccttgtgttggatgaggccacggcggccgtggacctggaaacggacgacctcatc
cagtccaccatccggacgcagttcgaggactgcaccgtcctcaccatcgcccaccggctc
aacaccatcatggactacacaagggtgatcgtcttggacaaaggagaaatccaggagtac
ggcgccccctcggacctcctgcagcagagaggtcttttctacagcatggccaaagacgcc
ggcttggtgtga |
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