Pongo abelii (Sumatran orangutan): 100432995
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Entry
100432995 CDS
T01416
Gene name
NRG2
Definition
(RefSeq) pro-neuregulin-2, membrane-bound isoform isoform X1
KO
K05456
neuregulin 2
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04012
ErbB signaling pathway
pon05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100432995 (NRG2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100432995 (NRG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100432995 (NRG2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
pon04052
]
100432995 (NRG2)
Cytokines and growth factors [BR:
pon04052
]
Growth factors
Growth factors (RTK binding)
100432995 (NRG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Neuregulin
I-set
Ig_3
ig
Ig_2
C2-set_2
V-set
Ig_6
EGF
DUF3169
Motif
Other DBs
NCBI-GeneID:
100432995
NCBI-ProteinID:
XP_024103308
LinkDB
All DBs
Position
5
AA seq
853 aa
AA seq
DB search
MRQVCCSALPPPPLEKGRCSSYSDSSSSSERSSNSSSSSSENGSSSRSSSNNSSISRPAA
PPEPRPQKQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQ
DQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVIS
VGSCAPLERNQRYIFFLEPTEQPLVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKK
MKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKV
KVEDAGEYVCEAENILGKDTVRGRLYVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYY
IEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKHLGFELKEAEELYQKRVLTITGIC
VALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADY
ISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDS
QSGIMLSSVGTSKCNSPACVEARARRAAAHNLEERRRATAPPYHDSVDSLRDSPHSERYV
SALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAP
PGPGPGPGPGADMQRSYDSYYYPAAGPGPRRGTCALGGSLGSLPASPFRIPEDDEYETTQ
ECAPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASAS
DDDADDADGALAAESTPFLGLRGAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSR
GPPPRAKQDSAPL
NT seq
2562 nt
NT seq
+upstream
nt +downstream
nt
atgcggcaggtttgctgctcagcgctgccgccgccgccactggagaagggtcggtgcagc
agctacagcgacagcagcagcagcagcgagaggagcagcaacagcagcagcagcagcagc
gagaacggcagcagcagcaggagcagcagcaacaacagcagcatctctcgtcccgctgcg
cccccagagccgcggccgcagaaacagccgcagccccgcagccccgcagcccggagagcc
gccgcccgttcgcgagcagcagccgccggcggcatgaggcgcgacccggcccccggcttc
tccatgctgctcttcggtgtgtcgctcgcctgctactcgcccagcctcaagtcagtgcag
gaccaggcgtacaaggcacccgtggtggtggagggcaaggtacaggggctggccccagcc
ggcggctccagctccaacagcacccgagagccgcccgcctcgggtcgggtggcgttggta
aaggtgctggacaagtggccgctccggagcggggggctgcagcgcgagcaggtgatcagc
gtgggctcctgtgcgccgctcgaaaggaaccagcgctacatctttttcctggagcccacg
gaacagcccttagtctttaagacggcctttgcccctctcgataccaacggcaaaaatctc
aagaaagaggtgggcaagatcctgtgcactgactgcgccacccggcccaagttgaagaag
atgaagagccagacgggacaggtgggtgagaagcaatcgctgaagtgtgaggcagcagcc
ggtaatccccagccttcctaccgttggttcaaggatggcaaggagctcaaccgcagccga
gacattcgcatcaaatatggcaatggcagaaagaactcacgactacagttcaacaaggtg
aaggtggaggacgctggggagtatgtctgcgaggccgagaacatcctggggaaggacacc
gtccggggccggctttacgtcaacagcgtgagcaccaccctgtcatcctggtcggggcat
gcccggaagtgcaacgagacagccaagtcctattgtgtcaatggaggcgtctgctactac
atcgagggcatcaatcagctctcctgcaaatgtccaaatggattcttcggacagagatgt
ttggagaaactgcctttgcgattgtacatgccagatcctaagcaaaagcaccttggattt
gaattaaaggaagccgaggagctgtaccagaagagagtcctgaccatcacgggcatctgc
gtggctctgctggtcgtgggcatcgtctgtgtggtagcctactgcaagaccaaaaaacag
cggaagcagatgcacaaccacctccggcagaacatgtgcccggcccatcagaaccggagc
ttggccaatgggcccagccacccccggctggacccagaggagatccagatggcagattat
atttccaagaacgtgccagccacagaccatgtcatcaggagagaaactgagaccaccttc
tctgggagccactcctgttctccttctcaccactgctccacagccacacccacctccagc
cacagacatgagagccacacgtggagcctggaacgttctgagagcctgacttctgactcc
cagtcggggatcatgctatcatcagtgggtaccagcaaatgcaacagcccagcatgtgtg
gaggcccgggcaaggcgggcagcagcccacaacctggaggagcggcgcagggccaccgcg
ccaccctatcacgattccgtggactcccttcgcgactccccacacagtgagaggtacgtg
tcggccctgaccacgcccgcgcgcctctcgcccgtggacttccactactcgctggcgacg
caggtgccaactttcgagatcacgtcccccaactcggcgcacgccgtgtcgctgccgccg
gcggcacccatcagttaccgcctggccgagcagcagccgttactgcggcacccggcgccc
cccggcccgggacccgggcccgggcccggcgcagacatgcagcgcagctacgacagctac
tattaccccgcggcggggcccggaccgcggcgcgggacctgcgcgctcggcggtagcctg
ggcagcctgcccgccagccccttccgcatcccggaggacgacgagtacgagaccacgcag
gagtgcgcgcccccgccgccgccgcggccgcgcgcgcgcggtgcgtcccgcaggacgtcg
gcggggccccggcgctggcgccgctcgcgcctcaatgggctggcggcgcagcgcgcacgg
gcggcgcgggactcgctgtcgctgagcagcggctcgggcggcggctcggcatcggcgtcg
gacgacgacgcggacgacgcggacggggcgctggcggccgagagcacgcctttcctgggc
ctgcgcggggcgcacgacgcgctgcgctcggactcgccgccactgtgcccggcggccgac
agcaggacttactactccctggacagccacagcacgcgggccagcagcagacacagccgc
gggccgcccccgcgggccaagcaggactcggcgccactctag
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