Pongo abelii (Sumatran orangutan): 100433208
Help
Entry
100433208 CDS
T01416
Gene name
TGFB3
Definition
(RefSeq) transforming growth factor beta-3
KO
K13377
transforming growth factor beta-3
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04060
Cytokine-cytokine receptor interaction
pon04068
FoxO signaling pathway
pon04110
Cell cycle
pon04218
Cellular senescence
pon04350
TGF-beta signaling pathway
pon04390
Hippo signaling pathway
pon04933
AGE-RAGE signaling pathway in diabetic complications
pon05140
Leishmaniasis
pon05142
Chagas disease
pon05144
Malaria
pon05145
Toxoplasmosis
pon05146
Amoebiasis
pon05152
Tuberculosis
pon05161
Hepatitis B
pon05166
Human T-cell leukemia virus 1 infection
pon05200
Pathways in cancer
pon05210
Colorectal cancer
pon05211
Renal cell carcinoma
pon05212
Pancreatic cancer
pon05220
Chronic myeloid leukemia
pon05225
Hepatocellular carcinoma
pon05226
Gastric cancer
pon05321
Inflammatory bowel disease
pon05323
Rheumatoid arthritis
pon05410
Hypertrophic cardiomyopathy
pon05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100433208 (TGFB3)
04350 TGF-beta signaling pathway
100433208 (TGFB3)
04390 Hippo signaling pathway
100433208 (TGFB3)
04068 FoxO signaling pathway
100433208 (TGFB3)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100433208 (TGFB3)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100433208 (TGFB3)
04218 Cellular senescence
100433208 (TGFB3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100433208 (TGFB3)
09162 Cancer: specific types
05210 Colorectal cancer
100433208 (TGFB3)
05212 Pancreatic cancer
100433208 (TGFB3)
05225 Hepatocellular carcinoma
100433208 (TGFB3)
05226 Gastric cancer
100433208 (TGFB3)
05220 Chronic myeloid leukemia
100433208 (TGFB3)
05211 Renal cell carcinoma
100433208 (TGFB3)
09163 Immune disease
05323 Rheumatoid arthritis
100433208 (TGFB3)
05321 Inflammatory bowel disease
100433208 (TGFB3)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100433208 (TGFB3)
05414 Dilated cardiomyopathy
100433208 (TGFB3)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100433208 (TGFB3)
09171 Infectious disease: bacterial
05152 Tuberculosis
100433208 (TGFB3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100433208 (TGFB3)
05161 Hepatitis B
100433208 (TGFB3)
09174 Infectious disease: parasitic
05146 Amoebiasis
100433208 (TGFB3)
05144 Malaria
100433208 (TGFB3)
05145 Toxoplasmosis
100433208 (TGFB3)
05140 Leishmaniasis
100433208 (TGFB3)
05142 Chagas disease
100433208 (TGFB3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
pon04052
]
100433208 (TGFB3)
Cytokines and growth factors [BR:
pon04052
]
Cytokines
Transforming growth factors (RSTK binding)
100433208 (TGFB3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
Motif
Other DBs
NCBI-GeneID:
100433208
NCBI-ProteinID:
XP_002825003
Ensembl:
ENSPPYG00000006009
UniProt:
H2NLV1
A0A6D2YA46
LinkDB
All DBs
Position
14
AA seq
412 aa
AA seq
DB search
MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI
AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR
ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST
VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
NT seq
1239 nt
NT seq
+upstream
nt +downstream
nt
atgaagatgcacttgcaaagggctctggtggtcctggccctgctgaactttgccacggtc
agcctctctctgtccacttgcaccaccttggacttcggccacatcaagaagaagagggtg
gaagccattaggggacagatcttgagcaagctcaggctcacgagcccccctgagccaacg
gtgatgacccacgtcccctatcaggtcctggccctttacaacagcacccgggagctgctg
gaggagatgcatggggagagggaggaaggctgcacccaggaaaacaccgagtcggaatac
tatgccaaagaaatccataaattcgacatgatccaggggctggcggagcacaacgaactg
gctgtctgccccaaaggaattacctccaaggttttccgcttcaatgtgtcctcagtggag
aaaaatagaaccaacctgttccgagcagaattccgggtcttgcgggtgcccaaccccagc
tctaagcggaatgagcagaggatcgagctctttcagatccttcggccagatgagcacatt
gccaaacagcgctatatcggtggcaagaatctgcccacacggggcactgccgagtggctg
tccttcgatgtcactgacactgtgcgtgagtggctgttgagaagagagtccaacttaggt
ctagaaatcagcattcactgtccatgtcacacctttcagcccaatggagatatcctggaa
aacattcacgaggtgatggaaatcaaattcaaaggcgtggacaatgaggatgaccatggc
cgtggagatctggggcgcctcaagaagcagaaggatcaccacaaccctcatctaatcctc
atgatgattcccccacaccggctcgacaacccgggccaagggggtcagaggaagaagcgg
gccttggacaccaattactgcttccgcaacttggaggagaactgctgtgtgcgccccctc
tacattgacttccgacaggatctgggctggaagtgggtccatgaacctaagggctactat
gccaacttctgctcaggcccttgcccatacctccgcagtgcagacacaacccacagcacg
gtgctgggactgtacaacactctgaaccctgaagcatctgcctcgccttgctgcgtgccc
caggacctggagcccctgaccatcctgtactatgttgggaggacccccaaggtggagcag
ctctccaacatggtggtgaagtcttgtaaatgtagctga
Pongo abelii (Sumatran orangutan): 100459982
Help
Entry
100459982 CDS
T01416
Gene name
TGFB1
Definition
(RefSeq) transforming growth factor beta-1
KO
K13375
transforming growth factor beta-1
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04060
Cytokine-cytokine receptor interaction
pon04068
FoxO signaling pathway
pon04110
Cell cycle
pon04218
Cellular senescence
pon04350
TGF-beta signaling pathway
pon04380
Osteoclast differentiation
pon04390
Hippo signaling pathway
pon04659
Th17 cell differentiation
pon04672
Intestinal immune network for IgA production
pon04926
Relaxin signaling pathway
pon04932
Non-alcoholic fatty liver disease
pon04933
AGE-RAGE signaling pathway in diabetic complications
pon05140
Leishmaniasis
pon05142
Chagas disease
pon05144
Malaria
pon05145
Toxoplasmosis
pon05146
Amoebiasis
pon05152
Tuberculosis
pon05161
Hepatitis B
pon05166
Human T-cell leukemia virus 1 infection
pon05200
Pathways in cancer
pon05205
Proteoglycans in cancer
pon05210
Colorectal cancer
pon05211
Renal cell carcinoma
pon05212
Pancreatic cancer
pon05220
Chronic myeloid leukemia
pon05225
Hepatocellular carcinoma
pon05226
Gastric cancer
pon05321
Inflammatory bowel disease
pon05323
Rheumatoid arthritis
pon05410
Hypertrophic cardiomyopathy
pon05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100459982 (TGFB1)
04350 TGF-beta signaling pathway
100459982 (TGFB1)
04390 Hippo signaling pathway
100459982 (TGFB1)
04068 FoxO signaling pathway
100459982 (TGFB1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100459982 (TGFB1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100459982 (TGFB1)
04218 Cellular senescence
100459982 (TGFB1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
100459982 (TGFB1)
04672 Intestinal immune network for IgA production
100459982 (TGFB1)
09152 Endocrine system
04926 Relaxin signaling pathway
100459982 (TGFB1)
09158 Development and regeneration
04380 Osteoclast differentiation
100459982 (TGFB1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100459982 (TGFB1)
05205 Proteoglycans in cancer
100459982 (TGFB1)
09162 Cancer: specific types
05210 Colorectal cancer
100459982 (TGFB1)
05212 Pancreatic cancer
100459982 (TGFB1)
05225 Hepatocellular carcinoma
100459982 (TGFB1)
05226 Gastric cancer
100459982 (TGFB1)
05220 Chronic myeloid leukemia
100459982 (TGFB1)
05211 Renal cell carcinoma
100459982 (TGFB1)
09163 Immune disease
05323 Rheumatoid arthritis
100459982 (TGFB1)
05321 Inflammatory bowel disease
100459982 (TGFB1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100459982 (TGFB1)
05414 Dilated cardiomyopathy
100459982 (TGFB1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100459982 (TGFB1)
04933 AGE-RAGE signaling pathway in diabetic complications
100459982 (TGFB1)
09171 Infectious disease: bacterial
05152 Tuberculosis
100459982 (TGFB1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100459982 (TGFB1)
05161 Hepatitis B
100459982 (TGFB1)
09174 Infectious disease: parasitic
05146 Amoebiasis
100459982 (TGFB1)
05144 Malaria
100459982 (TGFB1)
05145 Toxoplasmosis
100459982 (TGFB1)
05140 Leishmaniasis
100459982 (TGFB1)
05142 Chagas disease
100459982 (TGFB1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
pon03110
]
100459982 (TGFB1)
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
pon04052
]
100459982 (TGFB1)
00536 Glycosaminoglycan binding proteins [BR:
pon00536
]
100459982 (TGFB1)
Chaperones and folding catalysts [BR:
pon03110
]
Intramolecular chaperones
Others
100459982 (TGFB1)
Cytokines and growth factors [BR:
pon04052
]
Cytokines
Transforming growth factors (RSTK binding)
100459982 (TGFB1)
Glycosaminoglycan binding proteins [BR:
pon00536
]
Heparan sulfate / Heparin
Growth factors/receptors
100459982 (TGFB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
Motif
Other DBs
NCBI-GeneID:
100459982
NCBI-ProteinID:
XP_009230906
Ensembl:
ENSPPYG00000010013
LinkDB
All DBs
Position
19
AA seq
390 aa
AA seq
DB search
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEI
YDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSKDNTLQVDINGFT
TGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgccgccctccgggctgcggctgctgccgctgctgctaccgctgctgtggctactggta
ctgacgcctggccggccggccgcgggactatccacctgcaagactatcgacatggagctg
gtgaagcgcaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggggaggtgccgcccggcccgctgcccgaggccgtgctcgccctc
tacaacagcacccgcgaccgggtggccggggagagtgcagagccggagcccgagcctgag
gccgactactacgccaaggaggtcacccgcgtgctaatggtggaaacccacaacgaaatc
tatgacaagttcaagcagagtacacacagcatatatatgttcttcaacacatcagagctc
cgagaagcagtacctgaacccgtgttgctctcccgggcagagctgcgtctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatacagcaacaattcctggcga
tacctcagcaaccggctgctggcacccagcgactcgccggagtggttgtcttttgatgtc
accggagttgtgcggcagtggttgagccgcggaggggaaattgagggctttcgccttagt
gcccactgctcctgtgacagcaaagataacacactgcaagtggacatcaacgggttcact
accggccgccgaggtgacctggccaccattcacggcatgaaccggcctttcctgcttctc
atggccaccccactggagagggcccagcatctgcaaagctcccggcaccgccgagccctg
gacaccaactactgcttcagctccacggagaagaactgctgcgtgcggcagctgtacatt
gacttccgcaaggacctcggctggaagtggatccacgagcccaagggctaccatgctaac
ttctgcctcgggccctgcccctacatttggagcctggacacgcagtacagcaaggtcctg
gccctgtacaaccagcataacccgggcgcctcggcggcgccgtgctgcgtgccgcaggcg
ctggagccgctgcccatcgtgtactacgtgggccgcaaacccaaggtggagcagctgtcc
aacatgatcgtgcgctcctgcaagtgcagctga
Pongo abelii (Sumatran orangutan): 100461291
Help
Entry
100461291 CDS
T01416
Gene name
TGFB2
Definition
(RefSeq) transforming growth factor beta-2 isoform X1
KO
K13376
transforming growth factor beta-2
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04060
Cytokine-cytokine receptor interaction
pon04068
FoxO signaling pathway
pon04110
Cell cycle
pon04218
Cellular senescence
pon04350
TGF-beta signaling pathway
pon04380
Osteoclast differentiation
pon04390
Hippo signaling pathway
pon04933
AGE-RAGE signaling pathway in diabetic complications
pon05140
Leishmaniasis
pon05142
Chagas disease
pon05144
Malaria
pon05145
Toxoplasmosis
pon05146
Amoebiasis
pon05152
Tuberculosis
pon05161
Hepatitis B
pon05166
Human T-cell leukemia virus 1 infection
pon05200
Pathways in cancer
pon05205
Proteoglycans in cancer
pon05206
MicroRNAs in cancer
pon05210
Colorectal cancer
pon05211
Renal cell carcinoma
pon05212
Pancreatic cancer
pon05220
Chronic myeloid leukemia
pon05225
Hepatocellular carcinoma
pon05226
Gastric cancer
pon05321
Inflammatory bowel disease
pon05323
Rheumatoid arthritis
pon05410
Hypertrophic cardiomyopathy
pon05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100461291 (TGFB2)
04350 TGF-beta signaling pathway
100461291 (TGFB2)
04390 Hippo signaling pathway
100461291 (TGFB2)
04068 FoxO signaling pathway
100461291 (TGFB2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100461291 (TGFB2)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100461291 (TGFB2)
04218 Cellular senescence
100461291 (TGFB2)
09150 Organismal Systems
09158 Development and regeneration
04380 Osteoclast differentiation
100461291 (TGFB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100461291 (TGFB2)
05206 MicroRNAs in cancer
100461291 (TGFB2)
05205 Proteoglycans in cancer
100461291 (TGFB2)
09162 Cancer: specific types
05210 Colorectal cancer
100461291 (TGFB2)
05212 Pancreatic cancer
100461291 (TGFB2)
05225 Hepatocellular carcinoma
100461291 (TGFB2)
05226 Gastric cancer
100461291 (TGFB2)
05220 Chronic myeloid leukemia
100461291 (TGFB2)
05211 Renal cell carcinoma
100461291 (TGFB2)
09163 Immune disease
05323 Rheumatoid arthritis
100461291 (TGFB2)
05321 Inflammatory bowel disease
100461291 (TGFB2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100461291 (TGFB2)
05414 Dilated cardiomyopathy
100461291 (TGFB2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100461291 (TGFB2)
09171 Infectious disease: bacterial
05152 Tuberculosis
100461291 (TGFB2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100461291 (TGFB2)
05161 Hepatitis B
100461291 (TGFB2)
09174 Infectious disease: parasitic
05146 Amoebiasis
100461291 (TGFB2)
05144 Malaria
100461291 (TGFB2)
05145 Toxoplasmosis
100461291 (TGFB2)
05140 Leishmaniasis
100461291 (TGFB2)
05142 Chagas disease
100461291 (TGFB2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
pon04052
]
100461291 (TGFB2)
00536 Glycosaminoglycan binding proteins [BR:
pon00536
]
100461291 (TGFB2)
Cytokines and growth factors [BR:
pon04052
]
Cytokines
Transforming growth factors (RSTK binding)
100461291 (TGFB2)
Glycosaminoglycan binding proteins [BR:
pon00536
]
Heparan sulfate / Heparin
Growth factors/receptors
100461291 (TGFB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
SPEG_u2
Motif
Other DBs
NCBI-GeneID:
100461291
NCBI-ProteinID:
XP_002809490
Ensembl:
ENSPPYG00000000213
UniProt:
A0A2J8RS20
LinkDB
All DBs
Position
1
AA seq
442 aa
AA seq
DB search
MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLNSPPEDYPEP
EEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSETVCPV
VTTPSGSVGSLCSRQSQVLCGYLDAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVF
RLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLH
HKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRK
KNSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW
KWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILY
YIGKTPKIEQLSNMIVKSCKCS
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgcactactgtgtgctgagcgcttttctgatcctgcatctggtcacggtcgcgctcagc
ctgtctacctgcagcacactcgatatggaccagttcatgcgcaagaggatcgaggcgatc
cgcgggcagatcctgagcaagctgaagctcaacagtcccccagaagactatcctgagcct
gaggaagtccccccggaggtgatttccatctacaacagcaccagggacttgctccaggag
aaggcgagccggagggcggccgcctgcgagcgcgagaggagcgacgaagagtactacgcc
aaggaggtttacaaaatagacatgccgcccttcttcccctccgaaactgtctgcccagtt
gttacaacaccctctggctcagtgggcagcttgtgctccagacagtcccaggtgctctgt
gggtaccttgatgccatcccgcccactttctacagaccttacttcagaattgttcgattt
gacgtctcagcaatggagaagaatgcttccaatttggtgaaagcagagttcagagtcttt
cgtttgcagaacccaaaagccagagtgcctgaacaacggattgagctgtatcagattctc
aagtccaaagatttaacatctccaacccagcgctacattgacagcaaagttgtgaaaaca
agagcagaaggcgaatggctctccttcgatgtaactgatgctgttcatgaatggcttcac
cataaagacaggaacctgggatttaaaataagcttacactgtccctgctgcacttttgta
ccatctaataattacatcatcccaaataaaagcgaagaactagaagcaagatttgcaggt
attgatggcacctccacatataccagtggtgatcagaaaactataaagtccactaggaaa
aaaaacagtgggaagaccccacatctcctgctaatgttattgccctcctacagacttgag
tcacaacagaccaaccggcggaagaagcgtgctttggatgcggcctattgctttagaaat
gtgcaggataattgctgcctacgtccactttacattgatttcaagagggatctagggtgg
aaatggatacacgaacccaaagggtacaatgccaacttctgtgctggagcatgcccgtat
ttatggagttcagacactcagcacagcagggtcctgagcttatataataccataaatcca
gaagcatctgcttctccttgctgcgtgtcccaagatttagaacctctaaccattctctac
tacattggaaaaacacccaagattgaacagctttctaatatgattgtaaagtcttgcaaa
tgcagctaa
DBGET
integrated database retrieval system
