Pongo abelii (Sumatran orangutan): 100433568
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Entry
100433568 CDS
T01416
Gene name
TBK1
Definition
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04014
Ras signaling pathway
pon04137
Mitophagy - animal
pon04140
Autophagy - animal
pon04620
Toll-like receptor signaling pathway
pon04621
NOD-like receptor signaling pathway
pon04622
RIG-I-like receptor signaling pathway
pon04623
Cytosolic DNA-sensing pathway
pon04657
IL-17 signaling pathway
pon05014
Amyotrophic lateral sclerosis
pon05022
Pathways of neurodegeneration - multiple diseases
pon05135
Yersinia infection
pon05160
Hepatitis C
pon05161
Hepatitis B
pon05162
Measles
pon05163
Human cytomegalovirus infection
pon05164
Influenza A
pon05165
Human papillomavirus infection
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05168
Herpes simplex virus 1 infection
pon05169
Epstein-Barr virus infection
pon05170
Human immunodeficiency virus 1 infection
pon05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100433568 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100433568 (TBK1)
04137 Mitophagy - animal
100433568 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100433568 (TBK1)
04621 NOD-like receptor signaling pathway
100433568 (TBK1)
04622 RIG-I-like receptor signaling pathway
100433568 (TBK1)
04623 Cytosolic DNA-sensing pathway
100433568 (TBK1)
04657 IL-17 signaling pathway
100433568 (TBK1)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100433568 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
100433568 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100433568 (TBK1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100433568 (TBK1)
05161 Hepatitis B
100433568 (TBK1)
05160 Hepatitis C
100433568 (TBK1)
05171 Coronavirus disease - COVID-19
100433568 (TBK1)
05164 Influenza A
100433568 (TBK1)
05162 Measles
100433568 (TBK1)
05168 Herpes simplex virus 1 infection
100433568 (TBK1)
05163 Human cytomegalovirus infection
100433568 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
100433568 (TBK1)
05169 Epstein-Barr virus infection
100433568 (TBK1)
05165 Human papillomavirus infection
100433568 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100433568 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pon04131
]
100433568 (TBK1)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
100433568 (TBK1)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: Other
IKK family [OT]
100433568 (TBK1)
Membrane trafficking [BR:
pon04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
100433568 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
Kinase-like
DUF713
CEP63
ubiquitin
Casc1_N
Motif
Other DBs
NCBI-GeneID:
100433568
NCBI-ProteinID:
XP_024112335
Ensembl:
ENSPPYG00000004728
LinkDB
All DBs
Position
12
AA seq
729 aa
AA seq
DB search
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCVRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQE
GTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQ
KMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgatttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttgaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgtgggagtttatacactgttttagaagaa
ccttctaatgcctatggactaccagaatctgaattcttaattgttttgcgagatgtggtg
ggtggaatgaatcatctacgagagaatggtatagtgcaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaagatggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
caccctgatatgtatgagagagcagtgctaagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaacattttaccatgcagctactggatcactgcca
tttagaccctttgaagggcctcgtaggaataaagaagtgatgtataaaataattacagga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
ggagacatgcctgtttcttgcagtctttctcggggtcttcaggttctacttacccctgtt
cttgcaaacatccttgaagcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgttttttcgctacaacaaatgaca
gctcataagatttatattcatagctataatactgctactgtatttcatgaactggtatat
aaacaaaccaaaattatttcttcaaatcaagaacttatctatgaagggcgacgcttagtc
ttagaacctggaagactggcacaacatttccctaaaactactgaggaaaaccctatattt
gtagtaagccgggaacctctgaataccataggattaatatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagacggggatgctagcatggctaaggcaataacaggg
gttgtgtgttatgcctgcagaattgccagtaccttactgctttatcaggaattaatgcga
aaggggatacgatggctgattgaattaattaaagatgattacaatgaaactgttcacaaa
aagacagaagttgtgatcacattggatttctgtgtcagaaacattgaaaaaactgtgaaa
gtatacgaaaagttgatgaagatcaacctagaagcggcagagttaggtgaaatttcagac
atacacacgaaattattgagactttccagttctcagggaacaatagaaaccagtcttcag
gatattgacagcagattgtctccaggtggatcgctggcagacgcatgggcacatcaagaa
ggcactcatccgaaagacagaaacgtagaaaaactacaagtcctgttaaattgcatgaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagattagcttataatgaagaa
caaatccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacacac
tttacagatgaatgtgttaaaaagtatgaggcatttttgaataagtcagaagaatggata
agaaagatgcttcatcttaggaaacagttattatctctgactaatcagtgttttgatatt
gaagaagaagtatcaaaatatcaagaatatactaatgagttacaagaaactctgcctcag
aaaatgtttacagcttccagtggaatcaaacataccatgaccccaatttatccaagttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagagatggaaggggtg
gttaaagaacttgctgaaaataaccacattttagaaaggtttggctctttaaccatggat
ggtggccttcgcaacgttgactgtctttag
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integrated database retrieval system
