Pongo abelii (Sumatran orangutan): 100434355
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Entry
100434355 CDS
T01416
Gene name
PRKCA
Definition
(RefSeq) protein kinase C alpha type isoform X1
KO
K02677
classical protein kinase C alpha type [EC:
2.7.11.13
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04010
MAPK signaling pathway
pon04012
ErbB signaling pathway
pon04014
Ras signaling pathway
pon04015
Rap1 signaling pathway
pon04020
Calcium signaling pathway
pon04066
HIF-1 signaling pathway
pon04070
Phosphatidylinositol signaling system
pon04071
Sphingolipid signaling pathway
pon04072
Phospholipase D signaling pathway
pon04150
mTOR signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04261
Adrenergic signaling in cardiomyocytes
pon04270
Vascular smooth muscle contraction
pon04310
Wnt signaling pathway
pon04360
Axon guidance
pon04370
VEGF signaling pathway
pon04510
Focal adhesion
pon04540
Gap junction
pon04613
Neutrophil extracellular trap formation
pon04650
Natural killer cell mediated cytotoxicity
pon04664
Fc epsilon RI signaling pathway
pon04666
Fc gamma R-mediated phagocytosis
pon04670
Leukocyte transendothelial migration
pon04713
Circadian entrainment
pon04720
Long-term potentiation
pon04723
Retrograde endocannabinoid signaling
pon04724
Glutamatergic synapse
pon04725
Cholinergic synapse
pon04726
Serotonergic synapse
pon04727
GABAergic synapse
pon04728
Dopaminergic synapse
pon04730
Long-term depression
pon04750
Inflammatory mediator regulation of TRP channels
pon04911
Insulin secretion
pon04912
GnRH signaling pathway
pon04916
Melanogenesis
pon04918
Thyroid hormone synthesis
pon04919
Thyroid hormone signaling pathway
pon04921
Oxytocin signaling pathway
pon04925
Aldosterone synthesis and secretion
pon04926
Relaxin signaling pathway
pon04928
Parathyroid hormone synthesis, secretion and action
pon04929
GnRH secretion
pon04933
AGE-RAGE signaling pathway in diabetic complications
pon04935
Growth hormone synthesis, secretion and action
pon04960
Aldosterone-regulated sodium reabsorption
pon04961
Endocrine and other factor-regulated calcium reabsorption
pon04970
Salivary secretion
pon04971
Gastric acid secretion
pon04972
Pancreatic secretion
pon05017
Spinocerebellar ataxia
pon05022
Pathways of neurodegeneration - multiple diseases
pon05031
Amphetamine addiction
pon05032
Morphine addiction
pon05143
African trypanosomiasis
pon05146
Amoebiasis
pon05161
Hepatitis B
pon05163
Human cytomegalovirus infection
pon05164
Influenza A
pon05170
Human immunodeficiency virus 1 infection
pon05171
Coronavirus disease - COVID-19
pon05200
Pathways in cancer
pon05205
Proteoglycans in cancer
pon05206
MicroRNAs in cancer
pon05214
Glioma
pon05223
Non-small cell lung cancer
pon05225
Hepatocellular carcinoma
pon05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100434355 (PRKCA)
04012 ErbB signaling pathway
100434355 (PRKCA)
04014 Ras signaling pathway
100434355 (PRKCA)
04015 Rap1 signaling pathway
100434355 (PRKCA)
04310 Wnt signaling pathway
100434355 (PRKCA)
04370 VEGF signaling pathway
100434355 (PRKCA)
04066 HIF-1 signaling pathway
100434355 (PRKCA)
04020 Calcium signaling pathway
100434355 (PRKCA)
04070 Phosphatidylinositol signaling system
100434355 (PRKCA)
04072 Phospholipase D signaling pathway
100434355 (PRKCA)
04071 Sphingolipid signaling pathway
100434355 (PRKCA)
04151 PI3K-Akt signaling pathway
100434355 (PRKCA)
04150 mTOR signaling pathway
100434355 (PRKCA)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100434355 (PRKCA)
04540 Gap junction
100434355 (PRKCA)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
100434355 (PRKCA)
04650 Natural killer cell mediated cytotoxicity
100434355 (PRKCA)
04664 Fc epsilon RI signaling pathway
100434355 (PRKCA)
04666 Fc gamma R-mediated phagocytosis
100434355 (PRKCA)
04670 Leukocyte transendothelial migration
100434355 (PRKCA)
09152 Endocrine system
04911 Insulin secretion
100434355 (PRKCA)
04929 GnRH secretion
100434355 (PRKCA)
04912 GnRH signaling pathway
100434355 (PRKCA)
04921 Oxytocin signaling pathway
100434355 (PRKCA)
04926 Relaxin signaling pathway
100434355 (PRKCA)
04935 Growth hormone synthesis, secretion and action
100434355 (PRKCA)
04918 Thyroid hormone synthesis
100434355 (PRKCA)
04919 Thyroid hormone signaling pathway
100434355 (PRKCA)
04928 Parathyroid hormone synthesis, secretion and action
100434355 (PRKCA)
04916 Melanogenesis
100434355 (PRKCA)
04925 Aldosterone synthesis and secretion
100434355 (PRKCA)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100434355 (PRKCA)
04270 Vascular smooth muscle contraction
100434355 (PRKCA)
09154 Digestive system
04970 Salivary secretion
100434355 (PRKCA)
04971 Gastric acid secretion
100434355 (PRKCA)
04972 Pancreatic secretion
100434355 (PRKCA)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100434355 (PRKCA)
04961 Endocrine and other factor-regulated calcium reabsorption
100434355 (PRKCA)
09156 Nervous system
04724 Glutamatergic synapse
100434355 (PRKCA)
04727 GABAergic synapse
100434355 (PRKCA)
04725 Cholinergic synapse
100434355 (PRKCA)
04728 Dopaminergic synapse
100434355 (PRKCA)
04726 Serotonergic synapse
100434355 (PRKCA)
04720 Long-term potentiation
100434355 (PRKCA)
04730 Long-term depression
100434355 (PRKCA)
04723 Retrograde endocannabinoid signaling
100434355 (PRKCA)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100434355 (PRKCA)
09158 Development and regeneration
04360 Axon guidance
100434355 (PRKCA)
09159 Environmental adaptation
04713 Circadian entrainment
100434355 (PRKCA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100434355 (PRKCA)
05206 MicroRNAs in cancer
100434355 (PRKCA)
05205 Proteoglycans in cancer
100434355 (PRKCA)
05231 Choline metabolism in cancer
100434355 (PRKCA)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100434355 (PRKCA)
05214 Glioma
100434355 (PRKCA)
05223 Non-small cell lung cancer
100434355 (PRKCA)
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
100434355 (PRKCA)
05022 Pathways of neurodegeneration - multiple diseases
100434355 (PRKCA)
09165 Substance dependence
05031 Amphetamine addiction
100434355 (PRKCA)
05032 Morphine addiction
100434355 (PRKCA)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100434355 (PRKCA)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100434355 (PRKCA)
05161 Hepatitis B
100434355 (PRKCA)
05171 Coronavirus disease - COVID-19
100434355 (PRKCA)
05164 Influenza A
100434355 (PRKCA)
05163 Human cytomegalovirus infection
100434355 (PRKCA)
09174 Infectious disease: parasitic
05146 Amoebiasis
100434355 (PRKCA)
05143 African trypanosomiasis
100434355 (PRKCA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100434355 (PRKCA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100434355 (PRKCA)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pon04131
]
100434355 (PRKCA)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.13 protein kinase C
100434355 (PRKCA)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: AGC group
PKC family [OT]
100434355 (PRKCA)
Membrane trafficking [BR:
pon04131
]
Endocytosis
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
100434355 (PRKCA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
C1_1
PK_Tyr_Ser-Thr
C2
Pkinase_C
C1_2
APH
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100434355
NCBI-ProteinID:
XP_024090551
LinkDB
All DBs
Position
17
AA seq
614 aa
AA seq
DB search
MADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME
LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKDRLYFVME
YVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIK
IADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPF
DGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFR
RIDWEKLENREIQPPFKPRVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSY
VNPQFVHPILQSAV
NT seq
1845 nt
NT seq
+upstream
nt +downstream
nt
atggctgacgttttcccgggcaacgactccacggcgtctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcgcgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggtccacaagaggtgccatgaa
tttgttactttttcttgtccgggtgcggataagggacccgacactgatgaccccagaagc
aagcacaagttcaaaatccacacttacggaagccccaccttctgtgatcactgtgggtca
ctgctctatggacttatccatcaagggatgaaatgtgacacctgcgatatgaacgttcac
aagcaatgcgtcatcaatgtccccagcctctgcggaatggatcacactgagaagaggggg
cggatttacctaaaggctgaggttgctgacgaaaagctccatgtcacagtacgagatgca
aaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaactt
attcctgatcccaagaatgaaagcaagcaaaaaaccaaaaccatccgctccacactaaat
ccccagtggaatgagtcctttacattcaaattgaaaccttcagacaaagaccgacgactg
tctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatccctttcc
tttggagtttcggagctgatgaagatgccggccagtggatggtacaagttgcttaaccaa
gaagaaggtgagtactacaacgtacccattccggaaggggacgaagaaggaaacatggaa
ctcaggcagaaattcgagaaagccaaacttggccctgctggcaacaaagtcatcagtccc
tccgaagacaggaaacaaccttccaacaaccttgaccgagtgaaactcacggacttcaat
ttcctcatggtgttggggaaggggagttttggaaaggatcggctgtacttcgtcatggag
tatgtcaacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaacca
caagcagtattctatgcggcagagatttccatcggattgttcttccttcataaaagagga
atcatttatagggatctgaagttagataatgtcatgttggattcagaaggacatatcaaa
attgctgactttggaatgtgcaaggaacacatgatggatggagtcacgaccaggaccttc
tgtgggactccagattacattgccccagagataatcgcttatcagccgtatggaaaatct
gtggactggtgggcctatggcgtcctgttgtatgaaatgcttgctgggcagcctccattt
gatggtgaagatgaagacgagctatttcagtctatcatggagcacaacgtttcctatcca
aagtccttgtccaaggaggctgtttccatctgcaaaggactgatgaccaaacacccagcc
aagcggctgggctgtgggcctgagggggagagggacgtgagagaacatgccttcttccgg
aggatcgactgggaaaaactggagaacagggagatccagccaccattcaagcccagagtg
tgtggcaaaggagcagaaaactttgacaagttcttcacacgaggacagcccgtcttaaca
ccgcctgatcagctggttattgctaacatagaccagtctgattttgaagggttctcgtat
gtcaacccccagtttgtgcaccccatcttacagagtgcagtatga
DBGET
integrated database retrieval system
