KEGG   Pongo abelii (Sumatran orangutan): 100434355
Entry
100434355         CDS       T01416                                 

Gene name
PRKCA
Definition
(RefSeq) protein kinase C alpha type isoform X1
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon04010  MAPK signaling pathway
pon04012  ErbB signaling pathway
pon04014  Ras signaling pathway
pon04015  Rap1 signaling pathway
pon04020  Calcium signaling pathway
pon04066  HIF-1 signaling pathway
pon04070  Phosphatidylinositol signaling system
pon04071  Sphingolipid signaling pathway
pon04072  Phospholipase D signaling pathway
pon04150  mTOR signaling pathway
pon04151  PI3K-Akt signaling pathway
pon04261  Adrenergic signaling in cardiomyocytes
pon04270  Vascular smooth muscle contraction
pon04310  Wnt signaling pathway
pon04360  Axon guidance
pon04370  VEGF signaling pathway
pon04510  Focal adhesion
pon04540  Gap junction
pon04613  Neutrophil extracellular trap formation
pon04650  Natural killer cell mediated cytotoxicity
pon04664  Fc epsilon RI signaling pathway
pon04666  Fc gamma R-mediated phagocytosis
pon04670  Leukocyte transendothelial migration
pon04713  Circadian entrainment
pon04720  Long-term potentiation
pon04723  Retrograde endocannabinoid signaling
pon04724  Glutamatergic synapse
pon04725  Cholinergic synapse
pon04726  Serotonergic synapse
pon04727  GABAergic synapse
pon04728  Dopaminergic synapse
pon04730  Long-term depression
pon04750  Inflammatory mediator regulation of TRP channels
pon04911  Insulin secretion
pon04912  GnRH signaling pathway
pon04916  Melanogenesis
pon04918  Thyroid hormone synthesis
pon04919  Thyroid hormone signaling pathway
pon04921  Oxytocin signaling pathway
pon04925  Aldosterone synthesis and secretion
pon04926  Relaxin signaling pathway
pon04928  Parathyroid hormone synthesis, secretion and action
pon04929  GnRH secretion
pon04933  AGE-RAGE signaling pathway in diabetic complications
pon04935  Growth hormone synthesis, secretion and action
pon04960  Aldosterone-regulated sodium reabsorption
pon04961  Endocrine and other factor-regulated calcium reabsorption
pon04970  Salivary secretion
pon04971  Gastric acid secretion
pon04972  Pancreatic secretion
pon05017  Spinocerebellar ataxia
pon05022  Pathways of neurodegeneration - multiple diseases
pon05031  Amphetamine addiction
pon05032  Morphine addiction
pon05143  African trypanosomiasis
pon05146  Amoebiasis
pon05161  Hepatitis B
pon05163  Human cytomegalovirus infection
pon05164  Influenza A
pon05170  Human immunodeficiency virus 1 infection
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
pon05205  Proteoglycans in cancer
pon05206  MicroRNAs in cancer
pon05214  Glioma
pon05223  Non-small cell lung cancer
pon05225  Hepatocellular carcinoma
pon05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100434355 (PRKCA)
   04012 ErbB signaling pathway
    100434355 (PRKCA)
   04014 Ras signaling pathway
    100434355 (PRKCA)
   04015 Rap1 signaling pathway
    100434355 (PRKCA)
   04310 Wnt signaling pathway
    100434355 (PRKCA)
   04370 VEGF signaling pathway
    100434355 (PRKCA)
   04066 HIF-1 signaling pathway
    100434355 (PRKCA)
   04020 Calcium signaling pathway
    100434355 (PRKCA)
   04070 Phosphatidylinositol signaling system
    100434355 (PRKCA)
   04072 Phospholipase D signaling pathway
    100434355 (PRKCA)
   04071 Sphingolipid signaling pathway
    100434355 (PRKCA)
   04151 PI3K-Akt signaling pathway
    100434355 (PRKCA)
   04150 mTOR signaling pathway
    100434355 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100434355 (PRKCA)
   04540 Gap junction
    100434355 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100434355 (PRKCA)
   04650 Natural killer cell mediated cytotoxicity
    100434355 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    100434355 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    100434355 (PRKCA)
   04670 Leukocyte transendothelial migration
    100434355 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    100434355 (PRKCA)
   04929 GnRH secretion
    100434355 (PRKCA)
   04912 GnRH signaling pathway
    100434355 (PRKCA)
   04921 Oxytocin signaling pathway
    100434355 (PRKCA)
   04926 Relaxin signaling pathway
    100434355 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    100434355 (PRKCA)
   04918 Thyroid hormone synthesis
    100434355 (PRKCA)
   04919 Thyroid hormone signaling pathway
    100434355 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    100434355 (PRKCA)
   04916 Melanogenesis
    100434355 (PRKCA)
   04925 Aldosterone synthesis and secretion
    100434355 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100434355 (PRKCA)
   04270 Vascular smooth muscle contraction
    100434355 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    100434355 (PRKCA)
   04971 Gastric acid secretion
    100434355 (PRKCA)
   04972 Pancreatic secretion
    100434355 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100434355 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100434355 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    100434355 (PRKCA)
   04727 GABAergic synapse
    100434355 (PRKCA)
   04725 Cholinergic synapse
    100434355 (PRKCA)
   04728 Dopaminergic synapse
    100434355 (PRKCA)
   04726 Serotonergic synapse
    100434355 (PRKCA)
   04720 Long-term potentiation
    100434355 (PRKCA)
   04730 Long-term depression
    100434355 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    100434355 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100434355 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    100434355 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100434355 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100434355 (PRKCA)
   05206 MicroRNAs in cancer
    100434355 (PRKCA)
   05205 Proteoglycans in cancer
    100434355 (PRKCA)
   05231 Choline metabolism in cancer
    100434355 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100434355 (PRKCA)
   05214 Glioma
    100434355 (PRKCA)
   05223 Non-small cell lung cancer
    100434355 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    100434355 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    100434355 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100434355 (PRKCA)
   05032 Morphine addiction
    100434355 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100434355 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100434355 (PRKCA)
   05161 Hepatitis B
    100434355 (PRKCA)
   05171 Coronavirus disease - COVID-19
    100434355 (PRKCA)
   05164 Influenza A
    100434355 (PRKCA)
   05163 Human cytomegalovirus infection
    100434355 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100434355 (PRKCA)
   05143 African trypanosomiasis
    100434355 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100434355 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pon01001]
    100434355 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pon04131]
    100434355 (PRKCA)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     100434355 (PRKCA)
Protein kinases [BR:pon01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   100434355 (PRKCA)
Membrane trafficking [BR:pon04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    100434355 (PRKCA)
SSDB
Motif
Pfam: Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C C1_2 APH Kinase-like
Other DBs
NCBI-GeneID: 100434355
NCBI-ProteinID: XP_024090551
LinkDB
Position
17
AA seq 614 aa
MADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME
LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKDRLYFVME
YVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIK
IADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPF
DGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFR
RIDWEKLENREIQPPFKPRVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSY
VNPQFVHPILQSAV
NT seq 1845 nt   +upstreamnt  +downstreamnt
atggctgacgttttcccgggcaacgactccacggcgtctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcgcgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggtccacaagaggtgccatgaa
tttgttactttttcttgtccgggtgcggataagggacccgacactgatgaccccagaagc
aagcacaagttcaaaatccacacttacggaagccccaccttctgtgatcactgtgggtca
ctgctctatggacttatccatcaagggatgaaatgtgacacctgcgatatgaacgttcac
aagcaatgcgtcatcaatgtccccagcctctgcggaatggatcacactgagaagaggggg
cggatttacctaaaggctgaggttgctgacgaaaagctccatgtcacagtacgagatgca
aaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaactt
attcctgatcccaagaatgaaagcaagcaaaaaaccaaaaccatccgctccacactaaat
ccccagtggaatgagtcctttacattcaaattgaaaccttcagacaaagaccgacgactg
tctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatccctttcc
tttggagtttcggagctgatgaagatgccggccagtggatggtacaagttgcttaaccaa
gaagaaggtgagtactacaacgtacccattccggaaggggacgaagaaggaaacatggaa
ctcaggcagaaattcgagaaagccaaacttggccctgctggcaacaaagtcatcagtccc
tccgaagacaggaaacaaccttccaacaaccttgaccgagtgaaactcacggacttcaat
ttcctcatggtgttggggaaggggagttttggaaaggatcggctgtacttcgtcatggag
tatgtcaacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaacca
caagcagtattctatgcggcagagatttccatcggattgttcttccttcataaaagagga
atcatttatagggatctgaagttagataatgtcatgttggattcagaaggacatatcaaa
attgctgactttggaatgtgcaaggaacacatgatggatggagtcacgaccaggaccttc
tgtgggactccagattacattgccccagagataatcgcttatcagccgtatggaaaatct
gtggactggtgggcctatggcgtcctgttgtatgaaatgcttgctgggcagcctccattt
gatggtgaagatgaagacgagctatttcagtctatcatggagcacaacgtttcctatcca
aagtccttgtccaaggaggctgtttccatctgcaaaggactgatgaccaaacacccagcc
aagcggctgggctgtgggcctgagggggagagggacgtgagagaacatgccttcttccgg
aggatcgactgggaaaaactggagaacagggagatccagccaccattcaagcccagagtg
tgtggcaaaggagcagaaaactttgacaagttcttcacacgaggacagcccgtcttaaca
ccgcctgatcagctggttattgctaacatagaccagtctgattttgaagggttctcgtat
gtcaacccccagtttgtgcaccccatcttacagagtgcagtatga

KEGG   Pongo abelii (Sumatran orangutan): 100439900
Entry
100439900         CDS       T01416                                 

Gene name
PRKCB
Definition
(RefSeq) protein kinase C beta type isoform X2
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon04010  MAPK signaling pathway
pon04012  ErbB signaling pathway
pon04014  Ras signaling pathway
pon04015  Rap1 signaling pathway
pon04020  Calcium signaling pathway
pon04062  Chemokine signaling pathway
pon04064  NF-kappa B signaling pathway
pon04066  HIF-1 signaling pathway
pon04070  Phosphatidylinositol signaling system
pon04071  Sphingolipid signaling pathway
pon04150  mTOR signaling pathway
pon04270  Vascular smooth muscle contraction
pon04310  Wnt signaling pathway
pon04370  VEGF signaling pathway
pon04510  Focal adhesion
pon04540  Gap junction
pon04613  Neutrophil extracellular trap formation
pon04650  Natural killer cell mediated cytotoxicity
pon04662  B cell receptor signaling pathway
pon04666  Fc gamma R-mediated phagocytosis
pon04670  Leukocyte transendothelial migration
pon04713  Circadian entrainment
pon04720  Long-term potentiation
pon04723  Retrograde endocannabinoid signaling
pon04724  Glutamatergic synapse
pon04725  Cholinergic synapse
pon04726  Serotonergic synapse
pon04727  GABAergic synapse
pon04728  Dopaminergic synapse
pon04730  Long-term depression
pon04750  Inflammatory mediator regulation of TRP channels
pon04911  Insulin secretion
pon04912  GnRH signaling pathway
pon04916  Melanogenesis
pon04918  Thyroid hormone synthesis
pon04919  Thyroid hormone signaling pathway
pon04921  Oxytocin signaling pathway
pon04925  Aldosterone synthesis and secretion
pon04928  Parathyroid hormone synthesis, secretion and action
pon04929  GnRH secretion
pon04931  Insulin resistance
pon04933  AGE-RAGE signaling pathway in diabetic complications
pon04935  Growth hormone synthesis, secretion and action
pon04960  Aldosterone-regulated sodium reabsorption
pon04961  Endocrine and other factor-regulated calcium reabsorption
pon04970  Salivary secretion
pon04971  Gastric acid secretion
pon04972  Pancreatic secretion
pon04973  Carbohydrate digestion and absorption
pon05017  Spinocerebellar ataxia
pon05022  Pathways of neurodegeneration - multiple diseases
pon05031  Amphetamine addiction
pon05032  Morphine addiction
pon05140  Leishmaniasis
pon05143  African trypanosomiasis
pon05146  Amoebiasis
pon05161  Hepatitis B
pon05163  Human cytomegalovirus infection
pon05164  Influenza A
pon05170  Human immunodeficiency virus 1 infection
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
pon05205  Proteoglycans in cancer
pon05206  MicroRNAs in cancer
pon05214  Glioma
pon05223  Non-small cell lung cancer
pon05225  Hepatocellular carcinoma
pon05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100439900 (PRKCB)
   04012 ErbB signaling pathway
    100439900 (PRKCB)
   04014 Ras signaling pathway
    100439900 (PRKCB)
   04015 Rap1 signaling pathway
    100439900 (PRKCB)
   04310 Wnt signaling pathway
    100439900 (PRKCB)
   04370 VEGF signaling pathway
    100439900 (PRKCB)
   04064 NF-kappa B signaling pathway
    100439900 (PRKCB)
   04066 HIF-1 signaling pathway
    100439900 (PRKCB)
   04020 Calcium signaling pathway
    100439900 (PRKCB)
   04070 Phosphatidylinositol signaling system
    100439900 (PRKCB)
   04071 Sphingolipid signaling pathway
    100439900 (PRKCB)
   04150 mTOR signaling pathway
    100439900 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100439900 (PRKCB)
   04540 Gap junction
    100439900 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100439900 (PRKCB)
   04650 Natural killer cell mediated cytotoxicity
    100439900 (PRKCB)
   04662 B cell receptor signaling pathway
    100439900 (PRKCB)
   04666 Fc gamma R-mediated phagocytosis
    100439900 (PRKCB)
   04670 Leukocyte transendothelial migration
    100439900 (PRKCB)
   04062 Chemokine signaling pathway
    100439900 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    100439900 (PRKCB)
   04929 GnRH secretion
    100439900 (PRKCB)
   04912 GnRH signaling pathway
    100439900 (PRKCB)
   04921 Oxytocin signaling pathway
    100439900 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    100439900 (PRKCB)
   04918 Thyroid hormone synthesis
    100439900 (PRKCB)
   04919 Thyroid hormone signaling pathway
    100439900 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    100439900 (PRKCB)
   04916 Melanogenesis
    100439900 (PRKCB)
   04925 Aldosterone synthesis and secretion
    100439900 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100439900 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    100439900 (PRKCB)
   04971 Gastric acid secretion
    100439900 (PRKCB)
   04972 Pancreatic secretion
    100439900 (PRKCB)
   04973 Carbohydrate digestion and absorption
    100439900 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100439900 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100439900 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100439900 (PRKCB)
   04727 GABAergic synapse
    100439900 (PRKCB)
   04725 Cholinergic synapse
    100439900 (PRKCB)
   04728 Dopaminergic synapse
    100439900 (PRKCB)
   04726 Serotonergic synapse
    100439900 (PRKCB)
   04720 Long-term potentiation
    100439900 (PRKCB)
   04730 Long-term depression
    100439900 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    100439900 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100439900 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100439900 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100439900 (PRKCB)
   05206 MicroRNAs in cancer
    100439900 (PRKCB)
   05205 Proteoglycans in cancer
    100439900 (PRKCB)
   05231 Choline metabolism in cancer
    100439900 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100439900 (PRKCB)
   05214 Glioma
    100439900 (PRKCB)
   05223 Non-small cell lung cancer
    100439900 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    100439900 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    100439900 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    100439900 (PRKCB)
   05032 Morphine addiction
    100439900 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100439900 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100439900 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100439900 (PRKCB)
   05161 Hepatitis B
    100439900 (PRKCB)
   05171 Coronavirus disease - COVID-19
    100439900 (PRKCB)
   05164 Influenza A
    100439900 (PRKCB)
   05163 Human cytomegalovirus infection
    100439900 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100439900 (PRKCB)
   05140 Leishmaniasis
    100439900 (PRKCB)
   05143 African trypanosomiasis
    100439900 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100439900 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pon01001]
    100439900 (PRKCB)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     100439900 (PRKCB)
Protein kinases [BR:pon01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   100439900 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 Kinase-like CEP76-C2 APH
Other DBs
NCBI-GeneID: 100439900
NCBI-ProteinID: XP_002826292
LinkDB
Position
16
AA seq 671 aa
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEE
LRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGF
SYTNPEFVINV
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttc
gcccgcaaaggcgccctccggcagaagaacgtgcatgaggtcaagaaccacaaattcacc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc
gggaaacagggattccagtgccaagtttgctgctttgtggtgcacaagcggtgccatgaa
tttgtcacattctcctgccctggcgctgacaagggtccagcctctgatgacccccggagc
aaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgggtca
ctgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaatgtgcac
aagcgctgcgtgatgaacgttcccagcctgtgtggcacggaccacacggagcgccgcggc
cgcatctacatccaggcccacatcgacagggacgtcctcattgtcctcgtaagagatgct
aaaaaccttgtacctatggaccccaatggcctgtcagatccctacgtaaaactgaaactg
attcccgatcccaaaagtgagagcaaacagaagaccaaaaccatcaaatgctccctcaac
cccgagtggaacgagacatttagatttcagctgaaagaatcggacaaagacagaagactg
tcagtagagatctgggattgggatttgaccagcaggaatgacttcatgggatctttgtcc
tttgggatttctgaactgcaaaaagccagtgttgatggctggtttaagttactgagccag
gaggaaggcgagtacttcaatgtgcctgtgccaccagaaggaagtgaggccaatgaagaa
ctgcggcagaaatttgagagggccaagatcagtcaggggaccaaggtcccagaagaaaag
acgaccaacactgtctccaaatttgacaacaatggcaacagagaccggatgaaactgacc
gattttaacttcctaatggtgctggggaaaggcagctttggcaaggtcatgctttcagaa
cgaaaaggcacagatgagctctatgctgtgaagatcctgaagaaggacgttgtgatccaa
gatgatgacgtggagtgcactatggtggagaagcgggtgctggccctgcccgggaagcca
cccttcctgacccagctccactcctgcttccagaccatggaccgcctgtactttgtgatg
gagtacgtgaatgggggcgacctcatgtatcacatccagcaagtcggccggttcaaggag
ccccatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagtaag
ggcatcatttaccgtgacctaaaacttgacaacgtgatgctcgattctgaggggcacatc
aagattgctgattttggcatgtgtaaggaaaacatctgggatggggtgacaaccaagaca
ttctgtggcactccagactacatcgcccccgagataattgcttatcagccctatgggaag
tccgtggattggtgggcatttggagtcctgctgtatgaaatgttggctgggcaggcaccc
tttgaaggggaggatgaagatgaactcttccaatccatcatggaacacaacgtagcctat
cccaagtctatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacaccca
ggcaaacgtctgggttgtggacctgaaggcgaacgtgatatcaaagagcatgcatttttc
cggtatattgattgggagaaacttgaacgcaaagagatccagcccccatataagccaaaa
gctagagacaagagagacacctccaacttcgacaaagagttcaccagacagcctgtggaa
ctgacccccactgataaactcttcatcatgaacttggaccaaaatgaatttgctggcttc
tcttatactaacccagagtttgtcattaatgtgtag

KEGG   Pongo abelii (Sumatran orangutan): 100451563
Entry
100451563         CDS       T01416                                 

Gene name
PRKCG
Definition
(RefSeq) protein kinase C gamma type
  KO
K19663  classical protein kinase C gamma type [EC:2.7.11.13]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon04010  MAPK signaling pathway
pon04012  ErbB signaling pathway
pon04014  Ras signaling pathway
pon04015  Rap1 signaling pathway
pon04020  Calcium signaling pathway
pon04066  HIF-1 signaling pathway
pon04070  Phosphatidylinositol signaling system
pon04071  Sphingolipid signaling pathway
pon04150  mTOR signaling pathway
pon04270  Vascular smooth muscle contraction
pon04310  Wnt signaling pathway
pon04370  VEGF signaling pathway
pon04510  Focal adhesion
pon04540  Gap junction
pon04613  Neutrophil extracellular trap formation
pon04650  Natural killer cell mediated cytotoxicity
pon04666  Fc gamma R-mediated phagocytosis
pon04670  Leukocyte transendothelial migration
pon04713  Circadian entrainment
pon04720  Long-term potentiation
pon04723  Retrograde endocannabinoid signaling
pon04724  Glutamatergic synapse
pon04725  Cholinergic synapse
pon04726  Serotonergic synapse
pon04727  GABAergic synapse
pon04728  Dopaminergic synapse
pon04730  Long-term depression
pon04750  Inflammatory mediator regulation of TRP channels
pon04911  Insulin secretion
pon04916  Melanogenesis
pon04918  Thyroid hormone synthesis
pon04919  Thyroid hormone signaling pathway
pon04921  Oxytocin signaling pathway
pon04925  Aldosterone synthesis and secretion
pon04928  Parathyroid hormone synthesis, secretion and action
pon04929  GnRH secretion
pon04935  Growth hormone synthesis, secretion and action
pon04960  Aldosterone-regulated sodium reabsorption
pon04961  Endocrine and other factor-regulated calcium reabsorption
pon04970  Salivary secretion
pon04971  Gastric acid secretion
pon04972  Pancreatic secretion
pon05017  Spinocerebellar ataxia
pon05022  Pathways of neurodegeneration - multiple diseases
pon05031  Amphetamine addiction
pon05032  Morphine addiction
pon05143  African trypanosomiasis
pon05146  Amoebiasis
pon05161  Hepatitis B
pon05163  Human cytomegalovirus infection
pon05170  Human immunodeficiency virus 1 infection
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
pon05205  Proteoglycans in cancer
pon05206  MicroRNAs in cancer
pon05214  Glioma
pon05223  Non-small cell lung cancer
pon05225  Hepatocellular carcinoma
pon05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100451563 (PRKCG)
   04012 ErbB signaling pathway
    100451563 (PRKCG)
   04014 Ras signaling pathway
    100451563 (PRKCG)
   04015 Rap1 signaling pathway
    100451563 (PRKCG)
   04310 Wnt signaling pathway
    100451563 (PRKCG)
   04370 VEGF signaling pathway
    100451563 (PRKCG)
   04066 HIF-1 signaling pathway
    100451563 (PRKCG)
   04020 Calcium signaling pathway
    100451563 (PRKCG)
   04070 Phosphatidylinositol signaling system
    100451563 (PRKCG)
   04071 Sphingolipid signaling pathway
    100451563 (PRKCG)
   04150 mTOR signaling pathway
    100451563 (PRKCG)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100451563 (PRKCG)
   04540 Gap junction
    100451563 (PRKCG)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100451563 (PRKCG)
   04650 Natural killer cell mediated cytotoxicity
    100451563 (PRKCG)
   04666 Fc gamma R-mediated phagocytosis
    100451563 (PRKCG)
   04670 Leukocyte transendothelial migration
    100451563 (PRKCG)
  09152 Endocrine system
   04911 Insulin secretion
    100451563 (PRKCG)
   04929 GnRH secretion
    100451563 (PRKCG)
   04921 Oxytocin signaling pathway
    100451563 (PRKCG)
   04935 Growth hormone synthesis, secretion and action
    100451563 (PRKCG)
   04918 Thyroid hormone synthesis
    100451563 (PRKCG)
   04919 Thyroid hormone signaling pathway
    100451563 (PRKCG)
   04928 Parathyroid hormone synthesis, secretion and action
    100451563 (PRKCG)
   04916 Melanogenesis
    100451563 (PRKCG)
   04925 Aldosterone synthesis and secretion
    100451563 (PRKCG)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100451563 (PRKCG)
  09154 Digestive system
   04970 Salivary secretion
    100451563 (PRKCG)
   04971 Gastric acid secretion
    100451563 (PRKCG)
   04972 Pancreatic secretion
    100451563 (PRKCG)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100451563 (PRKCG)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100451563 (PRKCG)
  09156 Nervous system
   04724 Glutamatergic synapse
    100451563 (PRKCG)
   04727 GABAergic synapse
    100451563 (PRKCG)
   04725 Cholinergic synapse
    100451563 (PRKCG)
   04728 Dopaminergic synapse
    100451563 (PRKCG)
   04726 Serotonergic synapse
    100451563 (PRKCG)
   04720 Long-term potentiation
    100451563 (PRKCG)
   04730 Long-term depression
    100451563 (PRKCG)
   04723 Retrograde endocannabinoid signaling
    100451563 (PRKCG)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100451563 (PRKCG)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100451563 (PRKCG)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100451563 (PRKCG)
   05206 MicroRNAs in cancer
    100451563 (PRKCG)
   05205 Proteoglycans in cancer
    100451563 (PRKCG)
   05231 Choline metabolism in cancer
    100451563 (PRKCG)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100451563 (PRKCG)
   05214 Glioma
    100451563 (PRKCG)
   05223 Non-small cell lung cancer
    100451563 (PRKCG)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    100451563 (PRKCG)
   05022 Pathways of neurodegeneration - multiple diseases
    100451563 (PRKCG)
  09165 Substance dependence
   05031 Amphetamine addiction
    100451563 (PRKCG)
   05032 Morphine addiction
    100451563 (PRKCG)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100451563 (PRKCG)
   05161 Hepatitis B
    100451563 (PRKCG)
   05171 Coronavirus disease - COVID-19
    100451563 (PRKCG)
   05163 Human cytomegalovirus infection
    100451563 (PRKCG)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100451563 (PRKCG)
   05143 African trypanosomiasis
    100451563 (PRKCG)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100451563 (PRKCG)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pon01001]
    100451563 (PRKCG)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     100451563 (PRKCG)
Protein kinases [BR:pon01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   100451563 (PRKCG)
SSDB
Motif
Pfam: Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C Kinase-like APH
Other DBs
NCBI-GeneID: 100451563
NCBI-ProteinID: XP_024093868
Ensembl: ENSPPYG00000010365
LinkDB
Position
19
AA seq 687 aa
MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG
KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRSKHKFRLHSYSSPTFCDHCGSL
LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHITVGEA
RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL
SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ
KFERVRMGPSSSPIPSPSPSPTDPKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAER
RGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRL
YFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDA
EGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLA
GQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGEPTIRA
HGFFRWIDWERLERLEIPPPFRPRPCGRSGENFDKFFTRAAPALTPPDRLVLASIDQADF
QGFTYVNPDFVHPDARSPTSPVPVPVM
NT seq 2064 nt   +upstreamnt  +downstreamnt
atggctggtctgggccccggcggaggcgattcagaggggggaccccggcccctgttttgc
agaaagggggctctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgct
cgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggtatcgga
aagcagggcctgcaatgtcaagtctgcagctttgtggttcatcgacgatgccacgaattt
gtgaccttcgagtgtccaggcgctgggaagggcccccagacagacgacccccggagcaaa
cacaagttccgcttgcatagctacagcagccccaccttctgcgaccactgtggttccctc
ctctacgggcttgtgcaccagggcatgaaatgctcctgctgcgagatgaacgtgcacagg
cgctgtgtgcgtagcgtgccctccctgtgcggtgtggaccacaccgagcgccgcgggcgc
ctgcagctggagatccgggctcccacagcagatgagatccacataacggttggcgaggcc
cgtaacctaattcctatggaccccaatggtctctctgatccctatgtgaaactgaagctc
atcccagaccctcggaacctgacgaaacagaagacccgaacagtgaaagccacgctaaac
cctgtgtggaatgagacctttgtgttcaacctgaagccaggggatgtggagcgccggctc
agcgtggaggtgtgggactgggaccggacctcccgcaacgacttcatgggggccatgtcc
tttggcgtctcagagctgctcaaggcgcccgtggatggctggtacaagttactgaaccag
gaggagggcgagtattacaatgtgccggtggccgatgctgacaactgcagccttctccag
aaatttgagcgggtgcgaatgggcccctcttcctctcccatcccctccccttcccctagt
cccaccgaccccaagcgctgcttcttcggggcgagcccaggacgcctgcacatctccgac
ttcagcttcctcatggttctaggaaaaggcagttttgggaaggtgatgctggccgagcgc
aggggctctgatgagctctacgccatcaagatcttgaaaaaggacgtgatcgtccaggac
gacgatgtggactgcacgctggtggagaaacgtgtgctggcgctggggggccggggtcct
ggcggccggccccacttcctcacccagctccactccaccttccagaccccggaccgcctg
tatttcgtgatggagtacgtcaccgggggagacttgatgtaccacattcaacagctgggc
aagtttaaggagccccatgcagcgttctacgcggcagaaatcgccatcggcctcttcttc
cttcacaatcagggcatcatctacagggacctgaagctggacaatgtgatgctggatgct
gagggacacatcaagatcactgacttcggcatgtgtaaggagaacgtcttccccgggacg
acaacccgcaccttctgcgggaccccggactacatagccccggagatcattgcctaccag
ccctacgggaagtctgtcgattggtggtcctttggagttctgctgtatgagatgttggca
ggacagcctcccttcgatggggaggacgaggaggagctgtttcaggccatcatggaacaa
actgtcacctaccccaagtcgctttcccgggaagccgtggccatctgcaaggggttcctg
accaagcacccagggaagcgtctgggctcagggcctgatggggaacctaccatccgtgca
catggctttttccgctggattgactgggagcggctggaacgattggagatcccgcctcct
ttcagaccccgcccgtgtggccgcagcggcgagaactttgacaagttcttcacgcgggcg
gcgccagcgctgacccctccagaccgcctagtcctggccagcatcgaccaggccgatttc
cagggcttcacctacgtgaaccccgacttcgtgcacccggatgcccgcagccccaccagc
ccagtgcctgtgcccgtcatgtaa

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