Pongo abelii (Sumatran orangutan): 100436498
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Entry
100436498 CDS
T01416
Gene name
SRC
Definition
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon01522
Endocrine resistance
pon04012
ErbB signaling pathway
pon04015
Rap1 signaling pathway
pon04062
Chemokine signaling pathway
pon04137
Mitophagy - animal
pon04144
Endocytosis
pon04360
Axon guidance
pon04370
VEGF signaling pathway
pon04510
Focal adhesion
pon04520
Adherens junction
pon04530
Tight junction
pon04540
Gap junction
pon04611
Platelet activation
pon04613
Neutrophil extracellular trap formation
pon04625
C-type lectin receptor signaling pathway
pon04727
GABAergic synapse
pon04750
Inflammatory mediator regulation of TRP channels
pon04810
Regulation of actin cytoskeleton
pon04912
GnRH signaling pathway
pon04915
Estrogen signaling pathway
pon04917
Prolactin signaling pathway
pon04919
Thyroid hormone signaling pathway
pon04921
Oxytocin signaling pathway
pon04926
Relaxin signaling pathway
pon05100
Bacterial invasion of epithelial cells
pon05135
Yersinia infection
pon05152
Tuberculosis
pon05161
Hepatitis B
pon05163
Human cytomegalovirus infection
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05168
Herpes simplex virus 1 infection
pon05203
Viral carcinogenesis
pon05205
Proteoglycans in cancer
pon05219
Bladder cancer
pon05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100436498 (SRC)
04015 Rap1 signaling pathway
100436498 (SRC)
04370 VEGF signaling pathway
100436498 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100436498 (SRC)
04137 Mitophagy - animal
100436498 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100436498 (SRC)
04520 Adherens junction
100436498 (SRC)
04530 Tight junction
100436498 (SRC)
04540 Gap junction
100436498 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100436498 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100436498 (SRC)
04613 Neutrophil extracellular trap formation
100436498 (SRC)
04625 C-type lectin receptor signaling pathway
100436498 (SRC)
04062 Chemokine signaling pathway
100436498 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
100436498 (SRC)
04915 Estrogen signaling pathway
100436498 (SRC)
04917 Prolactin signaling pathway
100436498 (SRC)
04921 Oxytocin signaling pathway
100436498 (SRC)
04926 Relaxin signaling pathway
100436498 (SRC)
04919 Thyroid hormone signaling pathway
100436498 (SRC)
09156 Nervous system
04727 GABAergic synapse
100436498 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100436498 (SRC)
09158 Development and regeneration
04360 Axon guidance
100436498 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100436498 (SRC)
05203 Viral carcinogenesis
100436498 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
100436498 (SRC)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100436498 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
100436498 (SRC)
05152 Tuberculosis
100436498 (SRC)
05100 Bacterial invasion of epithelial cells
100436498 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
100436498 (SRC)
05168 Herpes simplex virus 1 infection
100436498 (SRC)
05163 Human cytomegalovirus infection
100436498 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
100436498 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100436498 (SRC)
01522 Endocrine resistance
100436498 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100436498 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pon04131
]
100436498 (SRC)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100436498 (SRC)
Protein kinases [BR:
pon01001
]
Non-receptor tyrosine kinases
SRC family
100436498 (SRC)
Membrane trafficking [BR:
pon04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
100436498 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
100436498 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
100436498 (SRC)
Macropinocytosis
Kinases
100436498 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
Motif
Other DBs
NCBI-GeneID:
100436498
NCBI-ProteinID:
XP_024094811
Ensembl:
ENSPPYG00000010985
LinkDB
All DBs
Position
20
AA seq
542 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPTENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYS
KHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR
VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLK
GETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI
EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV
LDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE
NL
NT seq
1629 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagccc
accgagaacgtgcacggcgctggcgggggcgctttccccgcctcgcagacccccagcaag
ccagcctcggccgacggccaccgcggcccaagtgcggccttcgcccccgcggccgccgag
cccaagctgttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcgggc
ccgctggccgggggagtgaccacctttgtggccctctatgactatgagtctaggacggag
acagacctgtccttcaagaaaggcgagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagagagggagactggtggctggcccactcgctcagcacaggacagacaggctac
atccccagcaactacgtggcgccctccgactccatccaggccgaggagtggtattttggc
aagatcaccagacgggagtcagagcggttactgctcaacgcggagaacccgagagggacc
ttcctcgtgcgagaaagtgagaccacgaaaggtgcctactgcctctcagtgtctgacttc
gacaacgccaagggcctcaacgtgaagcactacaagatccgcaagctggacagcggcggc
ttctacatcacctcccgcacccagttcaacagcctgcagcagctggtggcctactactcc
aaacacgccgacggcctgtgccaccgcctcaccaccgtgtgccccacgtccaagccacag
actcagggcctggccaaggatgcctgggagatccctcgggagtcgctgcggctggaggtc
aagctgggccagggctgctttggcgaggtgtggatggggacctggaacggtaccaccagg
gtggccatcaaaaccctgaagcccggcacgatgtctccagaggccttcctacaggaggcc
caggtcatgaagaagctgaggcatgagaagctggtgcagttgtatgctgtggtttcggag
gagcctatttacatcgtcacggagtacatgagcaaggggagtttgctggactttctcaag
ggggagacaggcaagtacctgcggctgcctcagctggtggacatggctgctcagatcgcc
tcaggcatggcatacgtggagcggatgaactacgtccaccgggaccttcgtgcagccaac
atcctggtgggagagaacctggtgtgcaaagtggccgacttcgggctggctcggctcatc
gaagacaatgagtacacggcgcggcaaggtgccaaattccccatcaagtggacggctccg
gaagctgccctctatggccgcttcaccatcaagtcggacgtatggtccttcgggatcctg
ctgactgagctcaccacaaagggacgggtgccctaccctgggatggtgaaccgcgaggtg
ctggaccaggtggagcggggctaccggatgccctgcccgccggagtgtcccgagtccctg
cacgacctcatgtgccagtgctggcggaaggagcctgaggagcggcccaccttcgagtac
ctgcaggccttcctggaggactacttcacgtccaccgagccccagtaccagcccggggag
aacctctag
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integrated database retrieval system
