Pongo abelii (Sumatran orangutan): 100440212
Help
Entry
100440212 CDS
T01416
Gene name
PDGFA
Definition
(RefSeq) platelet-derived growth factor subunit A isoform X1
KO
K04359
platelet-derived growth factor subunit A
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04015
Rap1 signaling pathway
pon04020
Calcium signaling pathway
pon04072
Phospholipase D signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04510
Focal adhesion
pon04540
Gap junction
pon04630
JAK-STAT signaling pathway
pon04810
Regulation of actin cytoskeleton
pon05200
Pathways in cancer
pon05202
Transcriptional misregulation in cancer
pon05206
MicroRNAs in cancer
pon05214
Glioma
pon05215
Prostate cancer
pon05218
Melanoma
pon05231
Choline metabolism in cancer
pon05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100440212 (PDGFA)
04014 Ras signaling pathway
100440212 (PDGFA)
04015 Rap1 signaling pathway
100440212 (PDGFA)
04630 JAK-STAT signaling pathway
100440212 (PDGFA)
04020 Calcium signaling pathway
100440212 (PDGFA)
04072 Phospholipase D signaling pathway
100440212 (PDGFA)
04151 PI3K-Akt signaling pathway
100440212 (PDGFA)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100440212 (PDGFA)
04540 Gap junction
100440212 (PDGFA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100440212 (PDGFA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100440212 (PDGFA)
05202 Transcriptional misregulation in cancer
100440212 (PDGFA)
05206 MicroRNAs in cancer
100440212 (PDGFA)
05231 Choline metabolism in cancer
100440212 (PDGFA)
09162 Cancer: specific types
05214 Glioma
100440212 (PDGFA)
05218 Melanoma
100440212 (PDGFA)
05215 Prostate cancer
100440212 (PDGFA)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100440212 (PDGFA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100440212 (PDGFA)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
pon04052
]
100440212 (PDGFA)
00536 Glycosaminoglycan binding proteins [BR:
pon00536
]
100440212 (PDGFA)
Cytokines and growth factors [BR:
pon04052
]
Growth factors
Growth factors (RTK binding)
100440212 (PDGFA)
Glycosaminoglycan binding proteins [BR:
pon00536
]
Heparan sulfate / Heparin
Growth factors/receptors
100440212 (PDGFA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDGF_N
PDGF
Motif
Other DBs
NCBI-GeneID:
100440212
NCBI-ProteinID:
XP_024097071
LinkDB
All DBs
Position
7
AA seq
220 aa
AA seq
DB search
MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLAHSQIHSIRDLQRLLEIDSVGSEESLD
TSLRVHGVHATKHASEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
PPCVEVKRCTGCCNTSSVKCQPSRIHHRSVKVAKVEYIRKKPKLKEVQVRLEEHLECACA
TTSLNPDYREEDTGEWLPSSASVLENRSSEPCFWGVRWPP
NT seq
663 nt
NT seq
+upstream
nt +downstream
nt
atgaggaccttggcttgcctgctgctcctcggctgcggatacctcgcccatgttctggcc
gaggaagccgagatcccccgcgaggtgatcgagaggctggcgcacagtcagatccacagc
atccgggacctccagcgactcctggagatagactccgtagggagtgaggagtctttggac
accagcctgagagttcacggggtccacgccactaagcatgcgtccgagaagcggcccctg
cccattcgaaggaagagaagcatcgaggaagctgtccccgctgtctgcaagaccaggacg
gtcatttacgagattcctcggagtcaggttgaccccacgtccgccaacttcctgatctgg
cccccgtgcgtggaggtgaaacgctgcaccggctgctgcaacaccagcagcgtcaagtgc
cagccctcacgcatccaccaccgcagtgtcaaggtcgccaaggtggaatacatcaggaag
aagccaaaattaaaagaagtccaggtgaggttagaggagcatttggagtgcgcctgcgcg
accaccagcctgaatccggattatcgggaagaggacacgggtgagtggctgccttcatcg
gcatcagtgttggagaacaggtcttcagagccgtgcttttggggtgttaggtggccccct
tga
Pongo abelii (Sumatran orangutan): 100455021
Help
Entry
100455021 CDS
T01416
Gene name
EGF
Definition
(RefSeq) pro-epidermal growth factor isoform X1
KO
K04357
epidermal growth factor
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04010
MAPK signaling pathway
pon04012
ErbB signaling pathway
pon04014
Ras signaling pathway
pon04015
Rap1 signaling pathway
pon04020
Calcium signaling pathway
pon04066
HIF-1 signaling pathway
pon04068
FoxO signaling pathway
pon04072
Phospholipase D signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04510
Focal adhesion
pon04540
Gap junction
pon04630
JAK-STAT signaling pathway
pon04810
Regulation of actin cytoskeleton
pon05160
Hepatitis C
pon05165
Human papillomavirus infection
pon05200
Pathways in cancer
pon05210
Colorectal cancer
pon05212
Pancreatic cancer
pon05213
Endometrial cancer
pon05214
Glioma
pon05215
Prostate cancer
pon05218
Melanoma
pon05219
Bladder cancer
pon05223
Non-small cell lung cancer
pon05224
Breast cancer
pon05226
Gastric cancer
pon05231
Choline metabolism in cancer
pon05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100455021 (EGF)
04012 ErbB signaling pathway
100455021 (EGF)
04014 Ras signaling pathway
100455021 (EGF)
04015 Rap1 signaling pathway
100455021 (EGF)
04630 JAK-STAT signaling pathway
100455021 (EGF)
04066 HIF-1 signaling pathway
100455021 (EGF)
04068 FoxO signaling pathway
100455021 (EGF)
04020 Calcium signaling pathway
100455021 (EGF)
04072 Phospholipase D signaling pathway
100455021 (EGF)
04151 PI3K-Akt signaling pathway
100455021 (EGF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100455021 (EGF)
04540 Gap junction
100455021 (EGF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100455021 (EGF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100455021 (EGF)
05231 Choline metabolism in cancer
100455021 (EGF)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100455021 (EGF)
09162 Cancer: specific types
05210 Colorectal cancer
100455021 (EGF)
05212 Pancreatic cancer
100455021 (EGF)
05226 Gastric cancer
100455021 (EGF)
05214 Glioma
100455021 (EGF)
05218 Melanoma
100455021 (EGF)
05219 Bladder cancer
100455021 (EGF)
05215 Prostate cancer
100455021 (EGF)
05213 Endometrial cancer
100455021 (EGF)
05224 Breast cancer
100455021 (EGF)
05223 Non-small cell lung cancer
100455021 (EGF)
09172 Infectious disease: viral
05160 Hepatitis C
100455021 (EGF)
05165 Human papillomavirus infection
100455021 (EGF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100455021 (EGF)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
pon04052
]
100455021 (EGF)
Cytokines and growth factors [BR:
pon04052
]
Growth factors
Growth factors (RTK binding)
100455021 (EGF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
EGF
cEGF
EGF_CA
DUF5050
EGF_3
Motif
Other DBs
NCBI-GeneID:
100455021
NCBI-ProteinID:
XP_002815105
Ensembl:
ENSPPYG00000014999
LinkDB
All DBs
Position
4
AA seq
1208 aa
AA seq
DB search
MLLTLIILLPVVLKFSFVSLSAPQHWSCPEGTLSGNGNSTCVGPAPFLIFSHGNSIFRID
TEGTNYAQLVVDAGVSVIMDFHYNEKRIYWVDLERQFLQRVFLNGSRQERVCNIEKNVSG
MAINWINEEVIWSNHQEGIITVTDMKGNNSHVLLSALKYPANIAVDPVERFIFWSSEVAG
SLYRADLDGVEVRALLETSEKITAVSLDVLEKRLFWIQYNREGSNSLICSCDYDGGSVHI
NKHPTQHNLFAMSLFGDHIFYSTWKTKTIWIANKHTGKDMVRINLHSSFVPPGELKVVHP
LAQPKAEDDAWEPEQKLRKLRKGNCSSTVCGQDPQSHLCTCAEGYALSRDRKYCEDVNEC
AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPSNVSECSHDCVLTSEGPL
CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCIPLSPVSWECDCFPGYDLQLDKKSCAASG
PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGTVYALDHDPVENKIYFAHTALKWIERAN
MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIIMKENISQP
RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVR
LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKEMLGTAWCSCREGFMKASDGKTC
LALDGHQLLAGGEVDQKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
STYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
EGYRGDGIHCLDIDECQLGVHSCGENANCTNTEGGYTCMCDGRLSEPGLICPDSTPPPHL
REDDHHYSVRNSDSGCPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
ELRHAGHGQQRKVTVVAVCVVVLVVLLLLSLWGAHYYRTQKLLSKNSKNPYEESSRDVRS
RRPADTEDGMSSCPQPWFVVIKEHKDLRNGSQPVAGEDGQAADVGSVQPTSWRQEPQLCG
MGTEQGCWIPVSSDNGSCPQVMERSFHMPSYGTQPLEGGVEKPHSLLSANPLWQQRALDP
PHQMELTQ
NT seq
3627 nt
NT seq
+upstream
nt +downstream
nt
atgctgctcactcttatcattctgttgccagtagttttaaaatttagttttgttagtctc
tcagcaccgcagcactggagctgtcctgaaggtactctctcaggaaatgggaattctact
tgtgtgggtcctgcacccttcttaattttctcccatggaaatagtatctttaggattgac
acagaaggaaccaattatgcgcaattggtggtggatgctggtgtctcagtgatcatggat
tttcattataatgagaaaagaatctattgggtggatttagaaagacaatttttgcaaaga
gtttttctgaacgggtcaaggcaagagagagtatgtaatatagagaaaaatgtttctgga
atggcaataaattggataaatgaagaagttatttggtcaaatcatcaggaaggaatcatt
acagtaacagatatgaaaggaaataattcccacgttcttttaagtgctttaaaatatcct
gcaaatatagcagttgatccagtagaaaggtttatattttggtcttcagaggtggctgga
agcctttatagagcagatctcgatggtgtggaagtgagggctctgctggagacatcagag
aaaataacagctgtgtcattggatgtgcttgagaagcggctgttttggattcagtacaac
agagaaggaagcaattctcttatttgctcctgtgattatgatggaggttctgtccacatt
aataaacatccaacacagcacaatttgtttgcaatgtccctttttggtgaccatatcttc
tattcaacatggaaaacgaagacaatttggatagccaacaaacacactgggaaggacatg
gttagaattaacctccattcatcatttgtaccacctggtgaactgaaagtagtgcatcca
ctcgcacaacccaaggcagaagatgatgcttgggagcctgagcagaaacttcgcaaattg
aggaaaggaaactgcagcagcactgtgtgtgggcaagacccccagtcacacttgtgcacg
tgtgcagagggatacgccctaagtcgagaccggaagtactgtgaagatgttaatgaatgt
gctttttggaatcatggctgtactcttgggtgtaaaaacacccctggatcctattactgc
acatgccctgtaggatttgttctgcttcctgatgggaaacgatgtcatcaacttgtttcc
tgtccaagcaatgtgtctgaatgcagccatgactgtgttctgacatcagaaggtccctta
tgtttctgtcctgaaggctcggtgcttgagagagatgggaaaacatgtagcggttgttcc
tcacctgataatggtggatgtagccagctctgcattcctctcagcccagtatcctgggaa
tgtgattgctttcctgggtatgacctacaactggataaaaaaagctgtgcagcttcagga
ccacaaccatttttgctgtttgccaattctcaagatattcgacacatgcattttgatgga
acagactatggaactctgctcagccagcagatgggaacggtttatgccctagatcatgac
cctgtggaaaataagatatactttgcccatacagccctgaagtggatagagagagctaat
atggatggttcccagcgagaaaggcttattgaggaaggagtagatgtgccagaaggtctt
gctgtggactggattggccgcagattctattggacagacagagggaaatctctgattgga
aggagtgatttaaatggaaaacgttccaaaataatcatgaaggagaacatctctcaacca
cgaggaattgctgttcatccaatggccaagagattattctggactgatacagggattaat
ccacgaattgaaagttcttccctccaaggccttggccgactggttatagccagctctgat
ctaatctggcccagtggaataacgattgacttcttaactgacaagttgtattggtgcgat
gccaagcagtctgtgattgaaatggccaatctggatggttcaaaacgccgaagacttacc
cagaatgatgtaggtcacccatttgctgtagccgtgtttgaggattatgtgtggttctca
gattgggctatgccatcagtaatgagagtaaacaagaggactggcaaagatagagtacgt
ctccaaggcagcatgctgaagccctcatcactggttgtggttcatccattggcaaaacca
ggagcagatccctgcttatatcaaaacggaggctgtgaacatatttgcaaagagatgctt
ggaactgcttggtgttcgtgtcgtgaaggttttatgaaagcctcagatgggaaaacgtgt
ctggctctggatggtcatcagctgttggcaggtggtgaagttgatcaaaagaaccaagta
acaccattggacatcttgtccaagactagagtgtcagaagataacattacagaatctcaa
cacatgctagtggctgaaatcatggtgtcagatcaagatgactgtgctcctgtgggatgc
agcacgtatgctcggtgtatttcagagggagaggatgccacatgtcagtgtttgaaagga
tttgctggggacggaaaactatgttctgatatagatgaatgtgagatgggtgtcccagtg
tgcccccctgcctcctccaagtgcatcaacaccgaagggggctatgtctgccggtgctca
gaaggctaccgaggagatgggattcactgtcttgatattgatgagtgccaactgggggtg
cacagctgtggagagaatgccaactgcacaaatacagagggaggctatacctgcatgtgt
gatggacgcctgtctgaaccaggactgatttgccctgactctactccaccccctcacctc
agggaagatgaccaccactattctgtaagaaatagtgactctggatgtcccctgtcccac
gatgggtactgcctccatgatggtgtgtgcatgtatattgaagcactggacaagtatgca
tgcaactgtgttgttggctacatcggggagcgatgtcagtaccgagacctgaagtggtgg
gaactgcgccacgctggccacgggcagcagcggaaggtcaccgtggtggctgtctgcgtg
gtggtgcttgtcgtgctgctcctcctgagcctgtggggggcccactactacaggactcag
aagctgctatcgaaaaattcaaagaatccttatgaggagtcgagcagagacgtgaggagt
cgcaggcctgctgacactgaggatgggatgtcctcttgccctcaaccttggtttgtggtt
ataaaggaacacaaagacctcaggaatgggagtcaaccagtggctggtgaggatggccag
gcagcagatgttgggtcagtgcaaccaacttcatggaggcaggagccccagttatgtgga
atgggcacagagcaaggctgctggattccagtatccagtgataacggctcctgtccccag
gtaatggagcgaagctttcatatgccctcctatgggacacagccccttgaagggggtgtt
gagaagccccattctctcctatcagctaacccattatggcaacaaagggccctggaccca
ccacaccaaatggagctgactcagtga
Pongo abelii (Sumatran orangutan): 100460243
Help
Entry
100460243 CDS
T01416
Gene name
PDGFB
Definition
(RefSeq) platelet-derived growth factor subunit B
KO
K17386
platelet-derived growth factor subunit B
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04015
Rap1 signaling pathway
pon04020
Calcium signaling pathway
pon04072
Phospholipase D signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04510
Focal adhesion
pon04540
Gap junction
pon04630
JAK-STAT signaling pathway
pon04810
Regulation of actin cytoskeleton
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05200
Pathways in cancer
pon05206
MicroRNAs in cancer
pon05211
Renal cell carcinoma
pon05214
Glioma
pon05215
Prostate cancer
pon05218
Melanoma
pon05231
Choline metabolism in cancer
pon05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100460243 (PDGFB)
04014 Ras signaling pathway
100460243 (PDGFB)
04015 Rap1 signaling pathway
100460243 (PDGFB)
04630 JAK-STAT signaling pathway
100460243 (PDGFB)
04020 Calcium signaling pathway
100460243 (PDGFB)
04072 Phospholipase D signaling pathway
100460243 (PDGFB)
04151 PI3K-Akt signaling pathway
100460243 (PDGFB)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100460243 (PDGFB)
04540 Gap junction
100460243 (PDGFB)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100460243 (PDGFB)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100460243 (PDGFB)
05206 MicroRNAs in cancer
100460243 (PDGFB)
05231 Choline metabolism in cancer
100460243 (PDGFB)
09162 Cancer: specific types
05214 Glioma
100460243 (PDGFB)
05218 Melanoma
100460243 (PDGFB)
05211 Renal cell carcinoma
100460243 (PDGFB)
05215 Prostate cancer
100460243 (PDGFB)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100460243 (PDGFB)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
100460243 (PDGFB)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100460243 (PDGFB)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
pon04052
]
100460243 (PDGFB)
00536 Glycosaminoglycan binding proteins [BR:
pon00536
]
100460243 (PDGFB)
Cytokines and growth factors [BR:
pon04052
]
Growth factors
Growth factors (RTK binding)
100460243 (PDGFB)
Glycosaminoglycan binding proteins [BR:
pon00536
]
Heparan sulfate / Heparin
Growth factors/receptors
100460243 (PDGFB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDGF
PDGF_N
Motif
Other DBs
NCBI-GeneID:
100460243
NCBI-ProteinID:
XP_002831201
Ensembl:
ENSPPYG00000011836
UniProt:
A0A6D2WYR8
H2P4F5
LinkDB
All DBs
Position
22
AA seq
241 aa
AA seq
DB search
MNRCWALFLYLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAEL
DLNMTRSHSGDELESLARGRRSLGSLTVAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
ETVAAARPVTRSPGGSQDQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
A
NT seq
726 nt
NT seq
+upstream
nt +downstream
nt
atgaatcgctgctgggcgctcttcctgtatctctgctgctacctgcgtctggtcagcgcc
gagggggaccccattcccgaggagctctatgagatgctgagtgaccactcgatccgctcc
ttcgatgatctccagcgcctgctgcacggagaccccggagaggaagatggggccgagttg
gacctgaacatgacccgctcccactctggagacgagctggagagcttggctcgtggaaga
aggagcctgggttctctgaccgttgctgagccggccatgatcgctgagtgcaagacgcgc
accgaggtgttcgagatctcccggcgcctcatagaccgcaccaatgccaacttcctggtg
tggccgccctgcgtggaggtgcagcgctgctccggctgctgcaacaaccgcaacgtgcag
tgccgccccacccaggtgcagctgcgacctgtccaggtgagaaagatcgagattgtgcgg
aagaagccaatctttaagaaggccacggtgacgctggaggaccacctggcatgcaagtgt
gagacagtggcggctgcacggcctgtgacccgaagcccggggggttcccaggaccagcga
gccaaaacgccccaaactcgggtgaccattcggacggtgcgagtccgccggccccctaag
ggcaagcaccggaaattcaagcacacgcatgacaagacggcactgaaggagaccctcgga
gcctag
DBGET
integrated database retrieval system
