Pongo abelii (Sumatran orangutan): 100440650 Help Entry 100440650         CDS       T01416                                  Gene name PIAS4 Definition (RefSeq) E3 SUMO-protein ligase PIAS4   KO K16065   E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04064   NF-kappa B signaling pathway pon04120   Ubiquitin mediated proteolysis pon04630   JAK-STAT signaling pathway pon05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:pon00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     100440650 (PIAS4)  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100440650 (PIAS4)    04064 NF-kappa B signaling pathway     100440650 (PIAS4)  09160 Human Diseases   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     100440650 (PIAS4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pon04121]     100440650 (PIAS4) Enzymes [BR:pon01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      100440650 (PIAS4) Ubiquitin system [BR:pon04121]  Ubiquitin ligases (E3)   UBL E3 ligases    100440650 (PIAS4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PINIT zf-MIZ zf-Nse SAP Sporozoite_P67 Motif Other DBs NCBI-GeneID:  100440650 NCBI-ProteinID:  XP_024093750 Ensembl:  ENSPPYG00000009394 LinkDB All DBs Position 19 AA seq 510 aa AA seqDB search MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKE LYETRYAKKNSEPAPQPHRPLDPLTMHSTYDRAGAVPRTPLAGPNIDYPVLYGKYLNGLG RLPAKTLKPEVRLVKLPFFNMLDELLKPTELVPQNNEKLQESPCIFALTPRQVELIRNSR ELQPGVKAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPC RPINLTHLMYLSSATNRITVTWGNYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCK ALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKK PTWMCPVCDKPAPYDQLIIDGLLSKILSECEDADEIEYLVDGSWCPIRAEKERSCSPQGA ILVLGPSDASGLLPAPSVNGSGALGSTGGGGPVGSVENGKPGADVVDLTLDSSSSSEDEE EEEEEEEDEDEEGPRPKRRCPFQKGLVPAC NT seq 1533 nt NT seq  +upstreamnt  +downstreamnt atggcggcggagctggtggaggccaaaaacatggtgatgagttttcgagtctccgacctt cagatgctcctgggtttcgtgggccggagtaagagcggactgaagcacgagctagtcacc agggccctccagctggtgcagtttgactgtagccctgagctgttcaagaagatcaaggag ctgtacgagacccgctacgccaagaagaactcggagcctgccccacagccacatcggccc ctggaccccctgaccatgcactccacctacgaccgggccggcgcggtgcccaggactcca ctggcaggccccaatattgactaccccgtgctctacggaaagtacttaaacggactggga cggttgcccgccaagaccctcaagccagaagtccgcctggtgaagctgccgttctttaat atgctggacgagctgctgaagcccaccgaattagtcccacagaacaacgagaagcttcag gagagcccatgcatcttcgcattgacgccaagacaggtggagttgatccggaactccagg gaactgcagcccggagttaaagccgtgcaggtcgtcctgagaatctgttactcagatacc agctgccctcaggaggaccagtacccgcccaacatcgctgtgaaggtcaaccacagctac tgctcagtcccgggctactacccctccaataagcccggggtggagcccaagaggccgtgc cgccccatcaacctcacccacctcatgtacctgtcctcggccaccaaccgcatcaccgtc acctgggggaactatggcaagagctactcggtggccctgtacctggtacggcagctgacc tcgtcggagctgctgcagaggctgaagaccattggggtgaagcacccggagctgtgcaag gcgctggtcaaggagaagctgcgccttgatcctgacagcgagatcgccaccaccggtgtg cgagtgtccctcatctgcccgctggtgaaaatgcggctctctgtgccctgccgggcagag acctgcgcccacttgcagtgcttcgacgccgtcttctacctgcagatgaacgagaagaag cccacctggatgtgccccgtgtgtgacaagccagccccctacgaccagctcatcattgat gggctcctctcgaagatcctgagcgagtgtgaggacgctgacgagatcgagtacctggtg gacggctcgtggtgcccgatccgcgccgaaaaggagcgcagctgcagcccgcagggcgcc atcctcgtgctgggcccctcggacgccagtgggctcctgcccgcccccagcgtcaacggg agcggtgccctgggcagcacaggtggcggcggccctgtgggcagcgtggagaatgggaag ccgggcgccgatgtggtggacctcacgctggacagctcatcatcctcggaggatgaggag gaggaggaagaggaggaggaagacgaggacgaagagggaccccggcccaagcgccgctgc cccttccagaagggcctggtgccggcctgctga

Pongo abelii (Sumatran orangutan): 100450652 Help Entry 100450652         CDS       T01416                                  Gene name PIAS1 Definition (RefSeq) E3 SUMO-protein ligase PIAS1 isoform X2   KO K04706   E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04120   Ubiquitin mediated proteolysis pon04630   JAK-STAT signaling pathway pon05160   Hepatitis C Brite KEGG Orthology (KO) [BR:pon00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     100450652 (PIAS1)  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100450652 (PIAS1)  09160 Human Diseases   09172 Infectious disease: viral    05160 Hepatitis C     100450652 (PIAS1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pon04121]     100450652 (PIAS1)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:pon04812]     100450652 (PIAS1) Enzymes [BR:pon01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.-        100450652 (PIAS1) Ubiquitin system [BR:pon04121]  Ubiquitin ligases (E3)   UBL E3 ligases    100450652 (PIAS1) Cytoskeleton proteins [BR:pon04812]  Eukaryotic cytoskeleton proteins   Septins    Septin associated proteins     100450652 (PIAS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PINIT zf-MIZ zf-Nse Motif Other DBs NCBI-GeneID:  100450652 NCBI-ProteinID:  XP_002825636 Ensembl:  ENSPPYG00000006589 UniProt:  A0A2J8UCA9 LinkDB All DBs Position 15 AA seq 651 aa AA seqDB search MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD NT seq 1956 nt NT seq  +upstreamnt  +downstreamnt atggcggacagtgcggaactaaagcaaatggttatgagccttagagtttctgaactccaa gtactgttgggctacgctgggagaaacaagcacggacgcaaacacgaacttctcacaaaa gccctgcatttgctaaaggctggctgtagtcctgctgtacaaatgaaaattaaggaactc tataggcggcggttcccgcagaaaatcatgacacctgcagacttgtccatccccaacgta cattcaagtcctatgccagcaactttgtctccatctaccattccacaactcacttacgat ggtcaccctgcatcatcgccattacttcctgtttctcttctgggacctaaacatgaactg gaactcccacatcttacatcagctcttcacccagtccatccggatataaaacttcaaaaa ttaccattttatgatttactggatgaactgataaaacccaccagtctagcatcagacaac agtcagcgctttcgagaaacctgttttgcatttgccttgacaccacaacaagtgcagcaa atcagtagttccatggatatttctgggaccaaatgtgacttcacagtacaggtccagtta aggttttgtttatcagaaaccagttgcccacaagaagatcacttcccacccaatctttgt gtgaaagtgaatacaaaaccttgcagccttccaggttaccttccacctacaaaaaatggc gtggaaccaaagcgacccagccgaccaattaatatcacctcacttgtccgactgtccaca acagtaccaaacacgattgttgtttcttggactgcagaaattggaagaaactattccatg gcagtgtatcttgtaaaacagttgtcctcaacagttcttcttcagaggttacgagcaaag ggaataaggaatccggatcattctagagctttaattaaagagaagttgactgcagatcca gacagtgaaatagctacaaccagcctaagggtttctctactatgtccacttggtaaaatg cggctgacaattccgtgtcgggcccttacatgttctcatctacaatgttttgacgcaact ctttacattcagatgaatgagaaaaaaccaacctgggtttgtcctgtctgtgataagaag gctccatatgaacaccttattattgatggcttgtttatggaaatcctaaagtactgtaca gactgtgatgaaatacagtttaaagaggatggcacttgggcaccgatgagatcgaaaaag gaagtacaagaagtttctgcctcttacaatggagtcgatggatgcttgagctccacattg gagcatcaggtagcgtctcaccaccagtcctcaaataaaaacaagaaagtagaagtgatt gacctaaccatagacagttcatctgatgaagaggaagaagagccatctgccaagaggacc tgtccttccctgtctcccacatcaccactaaataataaaggcattttaagtcttccacat caagcatctccagtatcccgcaccccaagccttcctgctgtagacacaagctacattaat acctccctcatccaagactataggcatcctttccacatgacacccatgccttacgactta caaggattagatttctttcctttcttatcaggagacaatcagcattacaacacctccttg cttgccgctgcagcagcagcagtttcagatgatcaagacctcctgcactcgtctcggttt ttcccgtatacctcctcacagatgtttcttgatcagttaagtgcaggaggcagtacttct ctgccaaccaccaatggaagcagtagtggcagtaacagcagcctggtttcttccaacagc ctaagggagagccatagccacactgtcacaaacaggagcagcacggacacggcatccatc tttggcatcataccagacattatttcattggactga

Pongo abelii (Sumatran orangutan): 100454767 Help Entry 100454767         CDS       T01416                                  Gene name PIAS2 Definition (RefSeq) E3 SUMO-protein ligase PIAS2 isoform X1   KO K16063   E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04120   Ubiquitin mediated proteolysis pon04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:pon00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     100454767 (PIAS2)  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100454767 (PIAS2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pon04121]     100454767 (PIAS2) Enzymes [BR:pon01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.-        100454767 (PIAS2) Ubiquitin system [BR:pon04121]  Ubiquitin ligases (E3)   UBL E3 ligases    100454767 (PIAS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PINIT zf-MIZ zf-Nse PHD Motif Other DBs NCBI-GeneID:  100454767 NCBI-ProteinID:  XP_024091920 LinkDB All DBs Position 18 AA seq 622 aa AA seqDB search MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL YRRRYPRTLEGLSDLSTIKSSVFSLDGSSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP ISSVSSDLPGLDFLSLIPVDPQQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSS SRSETGVITSSGSNIPDIISLD NT seq 1869 nt NT seq  +upstreamnt  +downstreamnt atggcggatttcgaagagttgaggaatatggtttctagttttagggtttctgaactacaa gtattactaggctttgctggacggaataaaagtggacgcaagcatgacctcctgatgagg gcgctgcatttattgaagagtggctgcagccctgcggttcagattaaaatccgagaattg tatagacgccgatatccacgaactcttgaaggactttctgatttatccacaatcaaatca tcggttttcagtttggatggtagctcatcacctgtagaacctgacttggccgtggctgga atccactcgttgccttccacttcagttacacctcactcaccatcctctcctgttggttct gtgctgcttcaagatactaagcccacatttgagatgcagcaaccatctcccccaattcct cctgtccatcctgatgtgcagttaaaaaatctgcccttttatgatgtccttgatgttctc atcaagcccacgagtttagttcaaagcagtattcagcgatttcaagagaagttttttatt tttgctttgacacctcaacaagttagagagatatgcatatccagggattttttgccaggt ggtaggagagattatacagtccaagttcagttgagactttgcctggcagagacaagttgc cctcaagaagataactatccaaatagtctatgtataaaagtaaatgggaagctatttcct ttacctggctatgcaccaccgcctaaaaatgggattgaacagaagcgccccggacgcccc ttgaatattacatctttagttaggttatcttcagctgtgccaaaccaaatttccatttct tgggcatcagaaattgggaagaattactctatgtctgtatatcttgtacggcagcttaca tcagccatgttattacagagattaaaaatgaaaggtattagaaaccctgatcattccaga gcactaattaaagaaaaacttaccgcagatcctgatagtgaaattgctacaactagcctt cgggtatccttgatgtgccctttaggaaaaatgaggctgacaatcccatgccgtgcagtg acttgtacacatctacagtgttttgatgctgccctttatctacaaatgaatgagaagaag cccacctggatttgtcctgtgtgtgacaaaaaagctgcctatgaaagtctaatattagat gggctttttatggaaattctcaatgactgttctgatgtggatgagatcaaattccaagaa gatggttcttggtgtccaatgagaccgaagaaagaagctatgaaagtatccagccaaccg tgtacaaaaatagaaagttcaagcgtcctcagtaagccttgttcagtgactgtagccagt gaggcaagcaagaagaaagtagatgttattgatcttacaatagaaagctcttctgacgaa gaggaagaccctcctgccaaaaggaaatgcatctttatgtcagaaacacaaagcagccca accaaaggggttctcatgtatcagccatcttctgtaagggtgcccagtgtgacttcggtt gatcctgctgctattccgccttcattaacagactactcagtaccattccaccatacgcca atatcaagcgtgtcatcagatttgccaggtttggattttctttcccttattccagttgat ccccagcagtactgtcctcctatgtttttggatagtctcacctcacccttaacagcaagc agtacgtctgtcaccaccaccagctcccatgaaagcagtactcatgttagttcatccagc agcaggagtgagacaggggtcataaccagcagtggaagtaacattcctgacatcatctca ttggactaa

Pongo abelii (Sumatran orangutan): 100461795 Help Entry 100461795         CDS       T01416                                  Gene name PIAS3 Definition (RefSeq) E3 SUMO-protein ligase PIAS3 isoform X1   KO K16064   E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04120   Ubiquitin mediated proteolysis pon04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:pon00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     100461795 (PIAS3)  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100461795 (PIAS3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pon04121]     100461795 (PIAS3) Enzymes [BR:pon01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.-        100461795 (PIAS3) Ubiquitin system [BR:pon04121]  Ubiquitin ligases (E3)   UBL E3 ligases    100461795 (PIAS3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PINIT zf-MIZ zf-Nse Motif Other DBs NCBI-GeneID:  100461795 NCBI-ProteinID:  XP_002810367 Ensembl:  ENSPPYG00000000934 UniProt:  A0A2J8SQ82 LinkDB All DBs Position 1 AA seq 628 aa AA seqDB search MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKEL YRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAPIPPTLLAPGTLLGPKREVDMHPPLP QPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLP GAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSR PINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHS RALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEK KPTWTCPVCDKKAPYESLIIDGLFMEILSSCSDCDEIQFMEDGSWCPMKPKKEASEVCPP PGYGLDGLQYSPVQEGNPSENKKKVEVIDLTIESSSDEEDLPPTKKHCSVTSAAIPALPG SKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQ HYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLAPTLGSSHRSATPAPPPGRVSSIVAPG GALREGHGGPLPSGPSLTGCRSDIISLD NT seq 1887 nt NT seq  +upstreamnt  +downstreamnt atggcggagctgggcgaattaaagcacatggtgatgagtttccgggtgtctgagcttcag gtgcttcttggctttgctggccggaataagagtggacggaagcacgagctcctggccaag gctctgcacctcctgaagtccagctgtgcccctagtgtccagatgaagatcaaagagctt taccgacgacgctttccccggaagaccctggggccctctgatctctcccttctctctttg ccccctggcacctctcctgtaggctcccctggtcctctagctcccattcccccaaccctg ttggcccctggcaccctgctgggccccaagcgtgaggtggacatgcacccccctctgccc cagcctgtgcaccctgatgtcaccatgaaaccattgcccttctatgaagtctatggggag ctcatccggcccaccacccttgcatccacttctagccagcggtttgaggaagcgcacttt acctttgccctcacaccccagcaagtgcagcagattcttacatccagagaggttctgcca ggagccaaatgtgattataccatacaggtgcagctaaggttctgtctctgtgagaccagc tgcccccaggaagattattttccccccaacctctttgtcaaggtcaatgggaaactgtgc cccctgccgggttaccttcccccaaccaagaatggggccgagcccaagaggcccagccgc cccatcaacatcacacccctggctcgactctcagccactgttcccaacaccattgtggtc aattggtcatctgagtttggacggaattactccttgtctgtgtacctggtgaggcagttg actgcaggaacccttctacaaaaactcagagcaaagggtatccggaacccagaccactcg cgggcactgatcaaggagaaattgactgctgatcctgacagtgaggtggccactacgagt ctccgggtgtcactcatgtgcccgctagggaagatgcgcctgactgtcccttgtcgtgcc ctcacctgtgcccacctgcagagcttcgatgctgccctttatctacagatgaatgagaag aagcctacgtggacatgtcctgtgtgtgacaagaaggctccctatgaatctcttatcatt gatggtttatttatggagattcttagttcctgttcagattgtgatgagatccaattcatg gaagatggatcctggtgcccaatgaaacccaagaaggaggcatctgaggtttgccccccg ccagggtatgggctggatggcctccagtacagcccagtccaggagggaaatccatcagag aataagaagaaggtcgaagttattgacttgacaatagaaagctcatcagatgaggaggat ctgccccctaccaagaagcactgttctgtcacctcagctgccatcccggccctacctgga agcaaaggagtcctgacgtctggccaccagccatcctcggtgctcaggagccctgctatg ggcacgttgggtggggatttcctgtccagtctcccactacatgagtacccacctgccttc ccactgggagccgacatccaaggtttagatttattttcatttcttcagacagagagtcag cactatggcccctccgtcatcacctcactagatgaacaggatgcccttggccactttttc cagtaccgagggaccccttctcactttctgggcccactggcccccacgttggggagttcc caccgcagcgccactccggcaccccctcctggccgtgtcagcagcattgtggcccctggg ggggccttgagggaggggcatggaggacccctgccctcaggtccctctttgactggctgt cggtcagacatcatttccctggactga

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