Pongo abelii (Sumatran orangutan): 100441912 Help Entry 100441912         CDS       T01416                                  Gene name ESR1 Definition (RefSeq) estrogen receptor isoform X2   KO K08550   estrogen receptor alpha Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon01522   Endocrine resistance pon04915   Estrogen signaling pathway pon04917   Prolactin signaling pathway pon04919   Thyroid hormone signaling pathway pon04961   Endocrine and other factor-regulated calcium reabsorption pon05200   Pathways in cancer pon05205   Proteoglycans in cancer pon05224   Breast cancer Brite KEGG Orthology (KO) [BR:pon00001]  09150 Organismal Systems   09152 Endocrine system    04915 Estrogen signaling pathway     100441912 (ESR1)    04917 Prolactin signaling pathway     100441912 (ESR1)    04919 Thyroid hormone signaling pathway     100441912 (ESR1)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     100441912 (ESR1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100441912 (ESR1)    05205 Proteoglycans in cancer     100441912 (ESR1)   09162 Cancer: specific types    05224 Breast cancer     100441912 (ESR1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100441912 (ESR1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:pon03000]     100441912 (ESR1)   09183 Protein families: signaling and cellular processes    03310 Nuclear receptors [BR:pon03310]     100441912 (ESR1) Transcription factors [BR:pon03000]  Eukaryotic type   Zinc finger    Cys4 estrogen receptor-like     100441912 (ESR1) Nuclear receptors [BR:pon03310]  3. Estrogen like   3A. Estrogen receptor    100441912 (ESR1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Oest_recep Hormone_recep zf-C4 ESR1_C Motif Other DBs NCBI-GeneID:  100441912 NCBI-ProteinID:  XP_002817538 Ensembl:  ENSPPYG00000017112 UniProt:  A0A6D2XRP1 A0A2J8XAF0 LinkDB All DBs Position 6 AA seq 595 aa AA seqDB search MIMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYVDSSKPAVYNYPEGAAY EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKH SKKNSPALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD KITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL LEMLDAHRLHAPTSRGGAPVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV NT seq 1788 nt NT seq  +upstreamnt  +downstreamnt atgatcatgaccctccacaccaaagcatccgggatggccctactgcatcagatccaaggg aacgagctggagcccctgaaccgtccgcagctcaagatccccctggagcggcccctgggc gaggtgtacgtggacagcagcaagcccgccgtgtacaactaccccgagggcgccgcctac gagttcaacgccgcggccgccgccaacgcgcaggtctacggtcagaccggcctcccctac ggccccgggtctgaggctgcggcgttcggctccaatggcctggggggtttccccccactc aacagcgtgtctccgagcccgctgatgcttctgcacccgccgccgcagctgtcgcctttc ctgcagccccacggccagcaggtgccctactacctggagaacgagcccagcggctacacg gtgcgcgaggccggcccgccggcattctacaggccaaattcagataatcgacgccagggt ggcagagaaagattggccagtaccaatgacaagggaagtatggctatggaatctgccaag gagactcgctactgtgcagtgtgcaatgactatgcttcaggctaccattatggagtctgg tcctgtgagggctgcaaggccttcttcaagagaagtattcaaggacataacgactatatg tgtccagccaccaaccaatgcaccattgataaaaacaggaggaagagctgccaggcctgc cggctccgcaaatgctacgaagtgggaatgatgaaaggtgggatacgaaaagaccgaaga ggagggagaatgttgaaacacaagcgccagagagatgatggggagggcaggggtgaagtg gggtctgctggagacatgagagctgccaacctttggccaagcccgctcatgatcaaacac tctaagaagaacagcccggccttgtccctgacggccgaccagatggtcagtgccttgttg gatgctgagccccccatactgtattccgagtatgatcctaccagacccttcagtgaggct tcgatgatgggcttactgaccaacctggcagacagggagctggttcacatgatcaactgg gcaaagagggtgccaggctttgtggatttgaccctccatgatcaggtccaccttctagaa tgtgcctggctagagatcctgatgattggtctcgtctggcgctccatggagcacccaggg aagctcctgtttgctcctaacttgctcttggacaggaaccagggaaaatgtgtagagggc atggtggagatcttcgacatgctgctggctacatcatctcggttccgcatgatgaatctg cagggagaggagtttgtgtgcctcaaatctattattttgcttaattctggagtgtacaca tttctgtccagcaccctgaagtctctggaagagaaggaccatatccaccgagtcctggac aagatcacagacactttgatccacctgatggccaaggcaggcctgaccctgcagcagcag caccggcggctggcccagctcctcctcatcctctcccacatcaggcacatgagtaacaaa ggcatggagcatctgtacagcatgaagtgcaagaacgtggtgcctctctatgacctgctg ctagagatgctggacgcccaccgcctgcatgcgcccactagccgtggaggggcgcccgtg gaggagacggaccaaagccacttggccaccgcgggctctacttcatcgcattccttgcaa aagtattacatcacgggggaggcagagggtttccctgccacagtctga

Pongo abelii (Sumatran orangutan): 100459579 Help Entry 100459579         CDS       T01416                                  Gene name ESR2 Definition (RefSeq) estrogen receptor beta isoform X1   KO K08551   estrogen receptor beta Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon01522   Endocrine resistance pon04915   Estrogen signaling pathway pon04917   Prolactin signaling pathway pon04929   GnRH secretion pon05200   Pathways in cancer pon05224   Breast cancer Brite KEGG Orthology (KO) [BR:pon00001]  09150 Organismal Systems   09152 Endocrine system    04929 GnRH secretion     100459579 (ESR2)    04915 Estrogen signaling pathway     100459579 (ESR2)    04917 Prolactin signaling pathway     100459579 (ESR2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100459579 (ESR2)   09162 Cancer: specific types    05224 Breast cancer     100459579 (ESR2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100459579 (ESR2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:pon03000]     100459579 (ESR2)   09183 Protein families: signaling and cellular processes    03310 Nuclear receptors [BR:pon03310]     100459579 (ESR2) Transcription factors [BR:pon03000]  Eukaryotic type   Zinc finger    Cys4 estrogen receptor-like     100459579 (ESR2) Nuclear receptors [BR:pon03310]  3. Estrogen like   3A. Estrogen receptor    100459579 (ESR2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ERbeta_N Hormone_recep zf-C4 Motif Other DBs NCBI-GeneID:  100459579 NCBI-ProteinID:  XP_002824882 Ensembl:  ENSPPYG00000005896 UniProt:  H2NLH9 LinkDB All DBs Position 14 AA seq 531 aa AA seqDB search MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVESHHEYPAMTFYSPAVMNYSIPS NVTNLEGGGPGRQTTSPNVLWPTPGHLSPLAVHRQLSHLYAEPQKSPWCEARSLEHTLPV NRETLKRKVSGNHCASPVTGPSSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQG HNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQL HCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLT KLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPD LVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVAATQD ADSSRKLAHLLNAMTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLSM KCKNVVPVYDLLLEMLNAQVLRGCKSSITGSECSPAEDSRSKEGSQNPQSQ NT seq 1596 nt NT seq  +upstreamnt  +downstreamnt atggatataaaaaactcaccatctagccttaattctccttcctcctacaactgcagtcaa tccatcttacccctggagcatggctccatatacataccttcttcctatgtagagagccac catgaatatccagccatgacattctatagccctgctgtgatgaattacagcattcccagc aatgtcactaacttggaaggtggtgggcctggtcggcagaccacaagcccaaatgtgttg tggccaacacctgggcacctttctcctttagcggtccatcgccagttatcacatctgtat gcagaacctcaaaagagtccctggtgtgaagcaagatcactagaacacaccttacctgta aacagagagacactgaaaaggaaggttagtgggaaccattgcgccagtcctgttactggt ccaagttcaaagagggacgctcacttctgcgctgtctgcagcgattacgcatcgggatat cactatggagtctggtcgtgtgaaggatgtaaggccttttttaaaagaagcattcaagga cataatgattatatttgtccagctacaaatcagtgtacaattgataaaaaccggcgcaag agctgccaggcctgccgacttcggaagtgttacgaagtgggaatggtgaagtgtggctcc cggagagagagatgtgggtaccgccttgtgcgaagacagagaagcgccgacgagcagctg cactgtgccggcaaggccaagagaagtggcggccacgcgccccgagtgcgggagctgctg ctggacgccctgagccccgagcagctggtgctcaccctcctggaggctgagccgccccat gtgctgatcagccgccccagcgcgcccttcaccgaggcctccatgatgatgtccctgacc aagttggccgacaaggagttggtacacatgatcagctgggccaagaagattcccggcttt gtggagctcagcctgtttgaccaagtgcggctcttggagagctgttggatggaggtgtta atggtggggctgatgtggcgctcaattgaccaccccggcaagcttatctttgctccagat cttgttctggacagggatgaggggaaatgcgtagaaggaattctggaaatctttgacatg ctcctggcaactacttcaaggtttcgagagttaaaactccaacacaaagagtatctctgt gtcaaggccatgatcctgctcaattccagtatgtaccctctggtcgcagcgacccaggat gctgacagcagccggaagctggcccacttgctgaacgccatgaccgatgctttggtctgg gtgatcgccaagagcggcatctcctcccagcagcaatccatgcgcctggctaacctcctg atgctcctgtcccatgtcaggcatgcgagtaacaagggcatggaacatctgctcagcatg aagtgcaaaaacgtggtcccagtgtatgacctgctgctggagatgctgaatgcccaagtg cttcgcgggtgcaagtcctccatcacggggtccgagtgcagcccagcagaggacagtaga agcaaagagggctcccagaacccacagtctcagtga

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