Pongo abelii (Sumatran orangutan): 100443314
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Entry
100443314 CDS
T01416
Gene name
CDK4
Definition
(RefSeq) cyclin-dependent kinase 4 isoform X2
KO
K02089
cyclin-dependent kinase 4 [EC:
2.7.11.22
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01522
Endocrine resistance
pon04110
Cell cycle
pon04115
p53 signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04218
Cellular senescence
pon04530
Tight junction
pon04660
T cell receptor signaling pathway
pon04933
AGE-RAGE signaling pathway in diabetic complications
pon04934
Cushing syndrome
pon05160
Hepatitis C
pon05162
Measles
pon05163
Human cytomegalovirus infection
pon05164
Influenza A
pon05165
Human papillomavirus infection
pon05166
Human T-cell leukemia virus 1 infection
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05169
Epstein-Barr virus infection
pon05200
Pathways in cancer
pon05203
Viral carcinogenesis
pon05212
Pancreatic cancer
pon05214
Glioma
pon05218
Melanoma
pon05219
Bladder cancer
pon05220
Chronic myeloid leukemia
pon05222
Small cell lung cancer
pon05223
Non-small cell lung cancer
pon05224
Breast cancer
pon05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
100443314 (CDK4)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100443314 (CDK4)
04115 p53 signaling pathway
100443314 (CDK4)
04218 Cellular senescence
100443314 (CDK4)
09144 Cellular community - eukaryotes
04530 Tight junction
100443314 (CDK4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
100443314 (CDK4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100443314 (CDK4)
05203 Viral carcinogenesis
100443314 (CDK4)
09162 Cancer: specific types
05212 Pancreatic cancer
100443314 (CDK4)
05225 Hepatocellular carcinoma
100443314 (CDK4)
05214 Glioma
100443314 (CDK4)
05220 Chronic myeloid leukemia
100443314 (CDK4)
05218 Melanoma
100443314 (CDK4)
05219 Bladder cancer
100443314 (CDK4)
05224 Breast cancer
100443314 (CDK4)
05222 Small cell lung cancer
100443314 (CDK4)
05223 Non-small cell lung cancer
100443314 (CDK4)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100443314 (CDK4)
04934 Cushing syndrome
100443314 (CDK4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100443314 (CDK4)
05160 Hepatitis C
100443314 (CDK4)
05164 Influenza A
100443314 (CDK4)
05162 Measles
100443314 (CDK4)
05163 Human cytomegalovirus infection
100443314 (CDK4)
05167 Kaposi sarcoma-associated herpesvirus infection
100443314 (CDK4)
05169 Epstein-Barr virus infection
100443314 (CDK4)
05165 Human papillomavirus infection
100443314 (CDK4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100443314 (CDK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100443314 (CDK4)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.22 cyclin-dependent kinase
100443314 (CDK4)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: CMGC group
CDK family
100443314 (CDK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
APH
Kdo
Kinase-like
FTA2
Motif
Other DBs
NCBI-GeneID:
100443314
NCBI-ProteinID:
XP_002823486
Ensembl:
ENSPPYG00000004703
UniProt:
A0A2J8UGT3
LinkDB
All DBs
Position
12
AA seq
303 aa
AA seq
DB search
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
NT seq
912 nt
NT seq
+upstream
nt +downstream
nt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggaggaggccttcccatcagcacagttcgtgaggtggctttactg
aggcgactggaggcttttgagcatcccaatgttgtccggctgatggacgtctgtgccaca
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaggaccta
aggacgtatctggacaaggcacccccaccaggcttgccagccgaaaccatcaaggatctg
atgcgccagtttctaagaggcctagatttccttcatgccaattgcatcgttcaccgagat
ctgaagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacccgtggttgttacactctggtac
cgagctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagcc
gaccagttgggcaaaatctttgacctgattgggctgcctccagaggatgactggcctcga
gatgtatccctgccccgtggagcctttccccccagagggccccgcccagtgcagtcggtg
gtacctgagatggaggagtcgggagcgcagctgctgctggaaatgctgacttttaaccca
cacaagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggt
aatccggagtga
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integrated database retrieval system
