Pongo abelii (Sumatran orangutan): 100443901
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Entry
100443901 CDS
T01416
Gene name
SIRT1
Definition
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD+-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00760
Nicotinate and nicotinamide metabolism
pon01100
Metabolic pathways
pon04068
FoxO signaling pathway
pon04152
AMPK signaling pathway
pon04211
Longevity regulating pathway
pon04213
Longevity regulating pathway - multiple species
pon04218
Cellular senescence
pon04922
Glucagon signaling pathway
pon05031
Amphetamine addiction
pon05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
100443901 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100443901 (SIRT1)
04152 AMPK signaling pathway
100443901 (SIRT1)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
100443901 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100443901 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
100443901 (SIRT1)
04213 Longevity regulating pathway - multiple species
100443901 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100443901 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
100443901 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pon03036
]
100443901 (SIRT1)
03029 Mitochondrial biogenesis [BR:
pon03029
]
100443901 (SIRT1)
Enzymes [BR:
pon01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
100443901 (SIRT1)
Chromosome and associated proteins [BR:
pon03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
100443901 (SIRT1)
Mitochondrial biogenesis [BR:
pon03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
100443901 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
100443901
NCBI-ProteinID:
XP_002820941
Ensembl:
ENSPPYG00000002401
LinkDB
All DBs
Position
10
AA seq
747 aa
AA seq
DB search
MADEAALALQPGGSPSAAGAEREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREV
PAAAGGCPAAAAALWREAEAEAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNFYD
EDDDDDEGEEEEEAAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRP
RIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDI
NTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIE
YFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRII
QCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPE
QFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLG
DCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHISEDSSS
PERSSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDL
KNVGSSTGEKNERTSVTGTVRKCWPNRVAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSD
SEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTD
GDDQEAIDEAISMKQEVTDMNYPSNKS
NT seq
2244 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggccctcgcccttcagcccggcggctccccctcggcggcgggggcc
gagagggaggccgcgtcgtcccccgccggggagccgctccgcaagaggccgcggagagac
ggtcccggcctcgagcggagcccgggcgagcccggtggggcggccccagagcgtgaggtg
ccggcggcggccgggggctgcccggctgcggcggcggcgctgtggcgggaggcggaggca
gaggcggcggcgggcggggagcaagaggcccaggcgactgcggcggctggggaaggagac
aatgggccgggcctgcagggcccatctcgggagccaccgctggccgacaacttctacgac
gaagacgacgacgacgacgagggcgaggaggaggaagaggcggcggcggcggcggcgatt
gggtaccgagataaccttctgttcggtgatgaaattatcactaatggttttcattcctgt
gaaagtgatgaggaggatagagcctcacatgcaagctctagtgactggactccgaggcca
cggataggtccatatacttttgttcagcaacatcttatgattggcacagatcctcgaaca
attcttaaagatttattgccggaaacaattcctccacctgagttggatgatatgacactg
tggcagattgttattaatatcctttcagaaccaccaaaaaggaaaaaaagaaaagatatt
aatacaattgaagatgctgtgaaattactgcaagagtgcaaaaaaattatagttctaact
ggagctggggtgtctgtttcatgtggaatacctgacttcaggtcaagggatggtatttat
gctcgccttgctgtagacttcccagatcttccagatcctcaagcgatgtttgatattgaa
tatttcagaaaagatccaagaccattcttcaagtttgcaaaggaaatatatcctggacaa
ttccaaccatcactctgtcacaaattcatagccttgtcagataaggaaggaaaactacta
cgcaactatacccagaacatagacacgctggagcaggttgcaggaatccaaaggataatt
cagtgtcatggttcctttgcaacagcatcttgcctgatttgtaaatacaaagttgactgt
gaagctgtacgaggagatatttttaatcaggtagttcctcgatgtcctaggtgcccagct
gatgaaccgcttgctatcatgaaaccagagattgtgttttttggtgaaaatttaccagaa
cagtttcatagagccatgaagtatgacaaagatgaagttgacctcctcattgttattggg
tcttccctcaaagtaagaccagtagcactaattccaagttccataccccatgaagtgcct
cagatattaattaatagagaacctttgcctcatctgcattttgatgtagagcttcttgga
gactgtgatgtcataattaatgaattgtgtcataggttaggtggtgaatatgccaaactt
tgctgtaaccctgtaaagctttcagaaattactgaaaaacctccacgaacacaaaaagaa
ttggcttatttgtcagagttgccacccacacctcttcatatttcagaagactcaagttca
ccagaaagaagttcaccaccagattcttcagtgattgtcacacttttagaccaagcagct
aagagtaatgatgatttagatgtgtctgaatcaaaaggttgtatggaagaaaaaccacag
gaagtacaaacttctaggaacgttgaaagtattgctgaacagatggaaaatccggatttg
aagaatgttggttccagtactggggagaaaaatgaaagaacttcagtgactggaacagtg
agaaaatgctggcctaatagagtggcaaaggagcagattagtaagcggcttgatggtaat
cagtatctgtttttgccaccaaatcgttacattttccatggcgctgaggtatattcagac
tctgaagatgacgtcttatcctctagttcttgtggcagtaacagtgatagtgggacatgc
cagagtccaagtttagaagaacccatggaggatgaaagtgaaattgaagaattctacaat
ggcttagaagatgagcctgatgttccagagagagctggaggagctggatttgggactgat
ggagatgatcaagaggcaattgatgaagctatatctatgaaacaggaagtaacagacatg
aactatccatcaaacaaatcatag
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integrated database retrieval system
