KEGG   Pongo abelii (Sumatran orangutan): 100446360
Entry
100446360         CDS       T01416                                 

Gene name
TMPRSS2
Definition
(RefSeq) transmembrane protease serine 2 isoform X1
  KO
K09633  transmembrane protease serine 2 [EC:3.4.21.-]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon05164  Influenza A
pon05171  Coronavirus disease - COVID-19
pon05202  Transcriptional misregulation in cancer
pon05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    100446360 (TMPRSS2)
  09162 Cancer: specific types
   05215 Prostate cancer
    100446360 (TMPRSS2)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100446360 (TMPRSS2)
   05164 Influenza A
    100446360 (TMPRSS2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pon01002]
    100446360 (TMPRSS2)
Enzymes [BR:pon01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.-  
     100446360 (TMPRSS2)
Peptidases and inhibitors [BR:pon01002]
 Serine peptidases
  Family S1: chymotrypsin family
   100446360 (TMPRSS2)
SSDB
Motif
Pfam: Trypsin SRCR_2 Hepsin-SRCR DUF1986 SRCR Trypsin_2 Ldl_recept_a
Other DBs
NCBI-GeneID: 100446360
NCBI-ProteinID: XP_024095307
LinkDB
Position
21
AA seq 492 aa
MALNSGSPPAIGPYYENHGYQPENPYPAQPTVAPSVYEVHPAQYYPSPVPQYAPRVLTQA
SNPVVHTQPKSPLGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSDSGIEC
NSSGTCISPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENY
GRAACRDMGYKDNFYSSQGIEDDSRATSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLR
CIACGVNLNSRRQSRIVGGQSALPGAWPWQVSLHVQNVHVCGGSIITREWIVTAAHCVEK
PLNNPWHWTAFAGILRQSFMFYESGHRVEKVISHPNYDSKTKNNDIALMKLQTPLTFNDL
VKPVCLPNPGMMLEPEQPCWISGWGATEEKGKTSDVLNEAMVPLIETQRCNSRYVYDNLI
TPAMICAGFLQGTVDSCQGDSGGPLVTWKDNVWWLIGDTSWGSGCAKAYRPGVYGNVTVF
TDWIYRQMRADG
NT seq 1479 nt   +upstreamnt  +downstreamnt
atggctttgaactcagggtcaccgccagctattggaccttactatgaaaatcatggatac
caaccggaaaacccctaccccgcacagcccactgtggcccccagtgtctacgaggtgcat
ccggctcagtactacccgtcccccgtgccccagtacgccccgagggtcctgacgcaggct
tccaaccccgtcgtccacacgcagcccaaatccccattggggacagtgtgcacctcaaag
actaagaaagcactgtgcatcaccttgaccctggggaccttcctcgtgggagctgcgctg
gccgctggcctactctggaagttcatgggcagcaagtgctccgactctgggatagagtgc
aactcctcaggtacctgcatcagcccctctaactggtgcgatggcgtgtcacactgcccc
ggcggggaggacgagaatcggtgtgttcgcctctatggaccaaacttcatccttcaggtg
tactcatctcagaggaagtcctggcaccctgtgtgccaagatgactggaacgagaactac
gggcgggcagcctgcagggacatgggctataaggataatttttactctagccaaggaata
gaggatgacagcagagccaccagctttatgaaactgaacacaagtgccggcaatgtcgat
atctataaaaaactgtaccacagtgatgcctgttcttcaaaagcagtggtttctttacgc
tgtatagcctgcggggtcaacttgaactcaagacgccagagcaggatcgtgggtggccag
agtgcgctcccgggggcctggccctggcaggtcagcctgcacgtccagaacgtccacgtg
tgcggaggctccatcatcacccgcgagtggatcgtgacagccgcccactgcgtggaaaaa
cctcttaacaatccatggcattggacggcatttgcggggattttgagacaatctttcatg
ttctatgaaagtggacaccgagtagaaaaagtgatttctcatccaaattatgactccaag
accaagaacaatgacattgcgctgatgaagctgcagacgcctctgactttcaatgactta
gtgaaaccagtgtgtctgcccaacccaggcatgatgctggagccagaacagccctgctgg
atttccgggtggggggccaccgaggagaaagggaagacctcagatgtgctgaacgaggcc
atggtgcctctcattgagacacagagatgcaacagcagatatgtctatgacaacctgatc
acaccagccatgatctgtgccggcttcctgcaggggaccgtcgattcttgccagggtgac
agtggagggcctctggtcacttggaaggacaatgtctggtggctgatcggggatacaagc
tggggttctggctgtgccaaagcttacagaccaggagtgtatgggaatgtgacggtattc
acggactggatttatcgacaaatgagggcagatggctaa

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