KEGG   Pongo abelii (Sumatran orangutan): 100446748
Entry
100446748         CDS       T01416                                 

Gene name
CDK2
Definition
(RefSeq) cyclin-dependent kinase 2
  KO
K02206  cyclin-dependent kinase 2 [EC:2.7.11.22]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04068  FoxO signaling pathway
pon04110  Cell cycle
pon04114  Oocyte meiosis
pon04115  p53 signaling pathway
pon04151  PI3K-Akt signaling pathway
pon04218  Cellular senescence
pon04914  Progesterone-mediated oocyte maturation
pon04934  Cushing syndrome
pon05160  Hepatitis C
pon05161  Hepatitis B
pon05162  Measles
pon05165  Human papillomavirus infection
pon05166  Human T-cell leukemia virus 1 infection
pon05169  Epstein-Barr virus infection
pon05200  Pathways in cancer
pon05203  Viral carcinogenesis
pon05215  Prostate cancer
pon05222  Small cell lung cancer
pon05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    100446748 (CDK2)
   04151 PI3K-Akt signaling pathway
    100446748 (CDK2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100446748 (CDK2)
   04114 Oocyte meiosis
    100446748 (CDK2)
   04115 p53 signaling pathway
    100446748 (CDK2)
   04218 Cellular senescence
    100446748 (CDK2)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    100446748 (CDK2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100446748 (CDK2)
   05203 Viral carcinogenesis
    100446748 (CDK2)
  09162 Cancer: specific types
   05226 Gastric cancer
    100446748 (CDK2)
   05215 Prostate cancer
    100446748 (CDK2)
   05222 Small cell lung cancer
    100446748 (CDK2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100446748 (CDK2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100446748 (CDK2)
   05161 Hepatitis B
    100446748 (CDK2)
   05160 Hepatitis C
    100446748 (CDK2)
   05162 Measles
    100446748 (CDK2)
   05169 Epstein-Barr virus infection
    100446748 (CDK2)
   05165 Human papillomavirus infection
    100446748 (CDK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pon01001]
    100446748 (CDK2)
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:pon03032]
    100446748 (CDK2)
   03036 Chromosome and associated proteins [BR:pon03036]
    100446748 (CDK2)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100446748 (CDK2)
Protein kinases [BR:pon01001]
 Serine/threonine kinases: CMGC group
  CDK family
   100446748 (CDK2)
DNA replication proteins [BR:pon03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   CDK (cyclin dependent kinase)
    100446748 (CDK2)
Chromosome and associated proteins [BR:pon03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Kinases and associated factors
    100446748 (CDK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 100446748
NCBI-ProteinID: XP_002823433
Ensembl: ENSPPYG00000004638
UniProt: A0A6D2W5S7 H2NHM8
LinkDB
Position
12
AA seq 298 aa
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
NT seq 897 nt   +upstreamnt  +downstreamnt
atggagaacttccaaaaggtggaaaagatcggagagggcacgtacggagttgtgtacaaa
gccagaaacaagttgacgggagaagtggtggcgcttaagaaaatccgcctggacactgag
actgagggtgtgcccagtactgccatccgagagatctctctgcttaaggagcttaaccat
cctaatattgtcaagctgctggatgtcattcacacagaaaataaactctacctggttttt
gaatttctgcaccaagatctcaagaaattcatggatgcctctgctctcactggcattcct
cttcccctcatcaagagctatctgttccagctgctccagggcctagctttctgccattct
catcgggtcctccaccgagaccttaaacctcagaatctgcttattaacacagagggggcc
atcaagctagcagactttggactagccagagcttttggagtccctgttcgtacttacacc
catgaggtggtgaccctgtggtaccgagctcctgaaatcctcctgggctgcaaatattac
tccacagctgtggacatctggagcctgggctgcatctttgctgagatggtgactcgccgg
gccctattccctggagattctgagattgaccagctcttccggatctttcggactctgggg
accccagatgaggtggtgtggccaggagttacttctatgcctgattacaagccaagtttc
cccaagtgggcccggcaagattttagtaaagttgtacctcccctggatgaagatggacgg
agcttgttatcgcaaatgctgcactacgaccctaacaagcggatttcggccaaggcagcc
ctggctcaccctttcttccaggatgtgaccaagccagtaccccatcttcgactctga

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