KEGG   Pongo abelii (Sumatran orangutan): 100447725Help
Entry
100447725         CDS       T01416                                 

Gene name
GSTO1
Definition
(RefSeq) glutathione S-transferase omega-1 isoform X2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00480  Glutathione metabolism
pon00980  Metabolism of xenobiotics by cytochrome P450
pon00982  Drug metabolism - cytochrome P450
pon00983  Drug metabolism - other enzymes
pon01524  Platinum drug resistance
pon05200  Pathways in cancer
pon05204  Chemical carcinogenesis
pon05225  Hepatocellular carcinoma
pon05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100447725 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100447725 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    100447725 (GSTO1)
   00983 Drug metabolism - other enzymes
    100447725 (GSTO1)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    100447725 (GSTO1)
   05204 Chemical carcinogenesis
    100447725 (GSTO1)
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    100447725 (GSTO1)
  09166 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    100447725 (GSTO1)
  09176 Drug resistance: Antineoplastic
   01524 Platinum drug resistance
    100447725 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:pon02000]
    100447725 (GSTO1)
Enzymes [BR:pon01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100447725 (GSTO1)
Transporters [BR:pon02000]
 Other Transporters
  Pores ion channels [TC:1]
   100447725 (GSTO1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C_3 GST_C GST_C_2 Glutaredoxin GST_C_5
Motif
Other DBs
NCBI-GeneID: 100447725
NCBI-ProteinID: XP_002821176
Ensembl: ENSPPYG00000002633
UniProt: H2NBI9
LinkDB All DBs
Position
10
AA seq 241 aa AA seqDB search
MSGESARSLGKGSAPPGPVPEGSIRVYSMRFCPFAERTLLVLKAKGIRHEVININLKNKP
EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGSSISMIDYLIWPW
FERLEAMKLNECVGHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
L
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgtccggggagtcagccaggagcttggggaagggaagcgcgcccccggggccggtcccg
gagggctcgatccgcgtctacagcatgaggttctgcccgtttgctgagaggacgcttctg
gtcctgaaggccaagggaatcaggcatgaagtcatcaatatcaacctgaaaaataagcct
gagtggttctttaagaaaaatccctttggtctggtgccagttctggaaaacagtcagggt
cagctgatctacgagtctgccatcacctgtgagtacctggatgaagcatacccagggaag
aagctgttgccagatgacccctatgagaaagcttgccagaagatgatcttagaattgttt
tctaaggtgccatccttggtaggaagctttattagaagccaaaataaagaagactatgct
ggcctaaaagaagaatttcgtaaagaatttaccaagctagaggaggttctgactaataag
aagacgaccttctttggtggcagttctatctcaatgattgattacctcatctggccctgg
tttgaacggctggaagcaatgaagttaaatgagtgtgtaggccacactccaaaactgaaa
ctgtggatggcagccatgaaggaagatcccacagtctcagccctgcttactagtgagaag
gactggcaaggtttcctagagctctacttacagaacagccctgaggcctgtgactatggg
ctctga

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