KEGG   Pongo abelii (Sumatran orangutan): 100448103Help
Entry
100448103         CDS       T01416                                 

Gene name
GSTO2
Definition
(RefSeq) glutathione S-transferase omega-2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00480  Glutathione metabolism
pon00980  Metabolism of xenobiotics by cytochrome P450
pon00982  Drug metabolism - cytochrome P450
pon00983  Drug metabolism - other enzymes
pon01524  Platinum drug resistance
pon05200  Pathways in cancer
pon05204  Chemical carcinogenesis
pon05225  Hepatocellular carcinoma
pon05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100448103 (GSTO2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100448103 (GSTO2)
   00982 Drug metabolism - cytochrome P450
    100448103 (GSTO2)
   00983 Drug metabolism - other enzymes
    100448103 (GSTO2)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    100448103 (GSTO2)
   05204 Chemical carcinogenesis
    100448103 (GSTO2)
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    100448103 (GSTO2)
  09166 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    100448103 (GSTO2)
  09176 Drug resistance: Antineoplastic
   01524 Platinum drug resistance
    100448103 (GSTO2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:pon02000]
    100448103 (GSTO2)
Enzymes [BR:pon01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100448103 (GSTO2)
Transporters [BR:pon02000]
 Other Transporters
  Pores ion channels [TC:1]
   100448103 (GSTO2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C_2 Glutaredoxin GST_C_3 GST_C
Motif
Other DBs
NCBI-GeneID: 100448103
NCBI-ProteinID: XP_002821177
Ensembl: ENSPPYG00000002634
UniProt: H2NBJ0
LinkDB All DBs
Position
10
AA seq 243 aa AA seqDB search
MSEDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
CKVPHLTKECLVALRCGRECTDLKAALRQEFGNLEEILEYQNTTFFGGTCISMIDYLLWP
WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
GLC
NT seq 732 nt NT seq  +upstreamnt  +downstreamnt
atgtctgaggatgcgaccaggaccctggggaaaggaagccagcccccagggccagtcccg
gaggggctgatccgcatctacagcatgaggttctgcccctattctcacaggacccgcctc
gtcctcaaggccaaagacatcagacatgaagtggtcaacattaacctgagaaacaagcct
gaatggtactatacaaagcacccttttggccacattcctgtcctggagaccagccaatgt
caactgatctatgaatctgtcatcgcttgtgagtacctggatgacgcttatccaggaagg
aagctgtttccatatgacccttatgaacgagctcgccaaaagatgttattggagctattt
tgtaaggtcccacatttgaccaaggagtgcctggtagcgctgagatgtgggagagaatgc
actgatctgaaggcagccctgcgtcaggaattcggcaacctggaagagattcttgagtat
cagaacaccaccttctttggtggaacctgtatatccatgattgattacctcctctggccc
tggtttgagcggctggatgtgtatgggatactggactgtgtgagccacacgccagccctg
cggctctggatatcagccatgaagtgggaccccacagtctgtgctcttctcatggataag
agcattttccagggcttcttgaatctctattttcagaacaatcctaatgcctttgacttt
gggctgtgctga

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