KEGG   Pongo abelii (Sumatran orangutan): 100448471
Entry
100448471         CDS       T01416                                 

Gene name
PTPN6
Definition
(RefSeq) tyrosine-protein phosphatase non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04520  Adherens junction
pon04630  JAK-STAT signaling pathway
pon04650  Natural killer cell mediated cytotoxicity
pon04660  T cell receptor signaling pathway
pon04662  B cell receptor signaling pathway
pon05140  Leishmaniasis
pon05205  Proteoglycans in cancer
pon05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100448471 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100448471 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100448471 (PTPN6)
   04660 T cell receptor signaling pathway
    100448471 (PTPN6)
   04662 B cell receptor signaling pathway
    100448471 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100448471 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100448471 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    100448471 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pon01009]
    100448471 (PTPN6)
Enzymes [BR:pon01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     100448471 (PTPN6)
Protein phosphatases and associated proteins [BR:pon01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    100448471 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 100448471
NCBI-ProteinID: XP_002822872
Ensembl: ENSPPYG00000004213
UniProt: A0A2J8TBK5
LinkDB
Position
12
AA seq 597 aa
MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVVLQGRDSNIPG
SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENTRVIVMTTREVEKGR
NKCVPYWPEVGMQRVYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
ITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
NT seq 1794 nt   +upstreamnt  +downstreamnt
atgctgtcccgtgggtggtttcaccgagacctcagtgggctggatgcagagaccctgctc
aagggccgaggtgtccatggtagcttcctggctcggcccagtcgcaagaaccagggtgac
ttctcgctctccgtcagggtaggggatcaggtgacccatattcggatccagaactcaggg
gatttctatgacctgtatggaggggagaagttcgcaacactgacagagctggtggagtac
tacactcagcagcagggcgtcctgcaggaccgcgatggcaccatcatccacctcaagtac
ccgctgaactgctccgatcccactagtgagaggtggtaccatggccacatgtctggaggg
caggcagagacgctgctgcaggccaagggcgagccctggacgtttcttgtgcgcgagagc
ctcagccagcctggggacttcgtgctgtctgtgctcagtgaccagcccaaggctggccca
ggctccccgctcagggtcacccacatcaaggtcatgtgtgagggtggacgctacacagtg
ggtggttcggagaccttcgacagcctcacggacctggtggagcatttcaagaagacgggg
attgaggaggcctcgggcgcctttgtctacctgcggcagccgtactacgccacgagggtg
aatgcggctgacattgagaaccgagtcttggaactgaacaagaagcaggagtccgaggat
acagccaaggctggcttctgggaggagtttgagagtttgcagaagcaggaggtgaagaac
ttgcaccagcgtctggaagggcagcggccagagaacaagggcaagaaccgctacaagaac
attctcccctttgaccacagccgagtggtcctgcagggacgtgacagtaacatccccggg
tccgactacatcaatgccaactacatcaagaaccagctgctaggccctgatgagaacgct
aagacctacatcgccagccagggctgtctggaggccacggtcaacgacttctggcagatg
gcgtggcaggagaacacacgcgtcattgtcatgaccacccgagaggtggagaaaggccgg
aacaaatgtgtcccatactggcccgaggtgggcatgcagcgcgtttatgggccctactct
gtgaccaactgcggggagcatgacacaaccgagtacaaactccgtaccttacaggtctcc
ccgctggacaatggagacctgattcgggagatctggcattaccagtacctgagctggccc
gaccatggggtccccagtgagcctgggggtgtcctcagcttcctggaccagatcaaccag
cggcaggaaagtctgcctcacgcggggcccatcatcgtgcactgcagcgccggcattggc
cgcacaggcaccatcattgtcatcgacatgctcatggagaacatctccaccaagggcctg
gactgtgacattgacatccagaagaccatccagatggtgcgggcgcagcgctcgggcatg
gtgcagacggaggcgcagtacaagttcatctacgtggccatcgcccagttcattgaaacc
accaagaagaagctggaggtcctgcagtcacagaagggccaggagtcggagtacgggaac
atcacctaccccccagccatgaagaatgcccatgccaaggcctcccgcacctcgtccaaa
cacaaggaggatgtgtatgagaacctgcacactaagaacaagagggaggagaaagtgaag
aagcagcggtcagcagacaaggagaagagcaagggttccctcaagaggaagtga

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