Pongo abelii (Sumatran orangutan): 100448476 Help Entry 100448476         CDS       T01416                                  Symbol ACACB Name (RefSeq) acetyl-CoA carboxylase 2   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00061   Fatty acid biosynthesis pon00620   Pyruvate metabolism pon00640   Propanoate metabolism pon01100   Metabolic pathways pon04152   AMPK signaling pathway pon04910   Insulin signaling pathway pon04920   Adipocytokine signaling pathway pon04922   Glucagon signaling pathway pon04931   Insulin resistance pon04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     100448476 (ACACB)    00640 Propanoate metabolism     100448476 (ACACB)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     100448476 (ACACB)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     100448476 (ACACB)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     100448476 (ACACB)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100448476 (ACACB)    04922 Glucagon signaling pathway     100448476 (ACACB)    04920 Adipocytokine signaling pathway     100448476 (ACACB)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100448476 (ACACB)    04931 Insulin resistance     100448476 (ACACB) Enzymes [BR:pon01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      100448476 (ACACB)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      100448476 (ACACB)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      100448476 (ACACB) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 Motif Other DBs NCBI-GeneID:  100448476 NCBI-ProteinID:  XP_024112956 LinkDB All DBs Position 12:107703520..107831152 Genome browser AA seq 2458 aa AA seqDB search MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANFIPSQEPFPDSDNSGETPQR NGEGHSLPNTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT GTQGLEAPDTDGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV ASSSRESTRKGSRASLGALSLEAYLITGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDVAKRIPVQAVWAGWGHASENPKL PELLCKNGVAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP LAIFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSIPPLARGHVIATRITSENPDE GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL NVADARFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAR LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPIFSIK LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD ELTSILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF GNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYIYDFPEMFRQALFKLWSSPDKYPK DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMIFANWRGF SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA DKESRGGVLEPEGTVEIKFRKKDLIKSMRRLDPAYKKLMEQLGEPDLSDKDRKDLEGRLK AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST NT seq 7377 nt NT seq  +upstreamnt  +downstreamnt atggtcttgcttctttgtctatcttgtctgattttctcctgtctgaccttttcctggtta aaaatctgggggaaaatgacggactccaagccgatcaccaagagtaaatcagaagcaaac ttcatcccgagccaggagccctttccagactctgataactcaggggagacaccacagaga aatggggagggccactctctgcccaacacccccagccaggccgagccagcctcccacaaa ggccccaaagatgccggtcggcggagaaactccctaccaccctcccaccagaagccccca aggaaccccctttcttccagtgacgcagcaccctccccagaacttcaagccaatgggact gggacacaaggtctggaggccccagataccgatggcctgtcctcctcagccaggccccag ggccagcaagctggctccccctccaaagaagacaagaagcaggcaaacatcaagaggcag ctgatgaccaacttcatcctgggctcttttgatgactactcctccgacgaggactctgtt gccagctcatctcgtgagtctacccggaagggcagccgggccagcttgggggccctgtcc ctggaggcttatctgatcacaggtgaagctgagacccgcgtccccactatgaggccgagc atgtcgggactccacctggtgaagaggggacgggaacacaagaagctggacctgcacaga gactttaccgtggcttctcccgctgagtttgtcacacgctttgggggggatcgggtcatc gagaaggtgcttattgccaacaatgggatcgccgctgtgaagtgcatgcgctccatccgc aggtgggcctatgagatgttccgcaatgagcgggccatccggtttgttgtgatggtgacc cccgaggaccttaaggccaacgcagagtacatcaagatggcagatcattacgtccccgtc ccaggagggcccaataacaacaactatgccaacgtggagctgattgtggacgttgccaag agaatccccgtgcaggcggtgtgggctggctggggccatgcttcagaaaaccctaaactt ccggagctgctgtgcaagaatggagttgctttcttaggccctcccagtgaggccatgtgg gccttaggagataagatcgcctccaccattgtcgcccagacgctacaggtcccaaccctg ccctggagtggaagcggcctgacagtggagtggacagaagatgatctgcagcagggaaaa agaatcagtgtcccagaagatgtttatgacaagggttgtgtgaaagacgtagatgagggc ttggaggcagcagaaagaattggttttccattgatgatcaaagcttctgaaggtggcgga gggaagggaatccggaaggctgagagtgcggaggacttcccgatccttttcagacaagta cagagtgagatcccaggctcgcccatctttctcatgaagctggcccagcacgcccgtcac ctggaagttcagatcctcgctgaccagtatgggaatgctgtgtctctgtttggtcgcgac tgctccatccagcggcggcatcagaagatcgttgaggaagcaccggccaccatcgccccg ctggccatattcgagttcatggagcagtgtgccgtccgcctggccaagaccgtgggctat gtgagtgcagggacagtggaatacctctatagccaggacggcagcttccacttcttggag ctgaatcctcgcttgcaggtggaacatccctgcacagaaatgattgctgacgtcaatctg ccggccgcccagctacagatcgccatgggcgtgccactgcaccggctgaaggatatccgg cttctgtacggagagtcaccatggggagtgactcccatttcttttgaaaccccctcaatc cctcccctcgcccgaggccacgtcattgccaccagaatcaccagcgaaaacccagatgag ggttttaagccgagctccgggactgtccaggaactgaatttccggagcagcaagaacgtg tggggttacttcagcgtggccgctactggaggcctgcacgagtttgcggattcccagttt gggcactgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggct ttgaaggaactgtccatccgaggcgactttaggactaccgtggaatacctcattaacctc ctggagaccgagagcttccagaacaacgacattgacaccgggtggttggactacctcatt gctgagaaagtgcaggcggagaaaccggatatcatgcttggggtggtatgcggggccttg aacgtggccgatgcgaggttcagaacgtgcatgacagatttcttacactccctggaaagg ggccaggtcctcccagcggattcgctactgaacctcgtagatgtggaattaatttacgga ggtgttaagtatattctcaaggtggcccggcagtctctgaccatgtttgttctcatcatg aatggctgccacatcgagattgacgcccaccggctgaatgatggggggctcctgctctcc tacaatgggaacagctacaccacctacatgaaggaagaggttgacagttaccgaattacc atcggcaataagacgtgtgtgtttgagaaggagaacgatcctacggtcctgagatccccc tcagctgggaagctgacacagtacacagtggaggatgggggccacgttgaggctgggagc agctacgctgagatggaggtgatgaagatgatcatgaccctgaacgtgcaggaaagtggc cgggtgaagtacatcaagcgtccaggtgctgtgctggaagcaggctgcgtggtggccagg ctggagcttgatgacccttctaaagtccacccggctgaaccgttcacaggagaactccct gcccagcagacactgcccatcctcggagaaaaactgcaccaggtcttccacagcgtcctg gaaaacctcaccaacgtcatgagtggcttttgtctgccagagcccatttttagcataaag ctgaaggagtgggtgcagaagctcatgatgaccctccggcacccgtcactgccgctgctg gagctgcaggagatcatgactagcgtggcaggccgcatccctgcccccgtggagaagtcg gtccgcagagtgatggcccagtatgccagcaacatcacctcggtgctgtgccagttcccc agccagcagatagccaccatcctggactgccacgcagccaccctgcagcggaaggccgat cgagaggtcttcttcatcaacacccagagcatcgtgcagttggtccagagataccgcagc gggatccgcggctatatgaaaacagtggtgttggatctcctgagaagatacttgcgtgtt gagcaccattttcagcaagcccactacgacaagtgtgtgataaacctcagggagcagttc aagccagacatgtcccaggtgttggactgcatcttctcccacgcgcaggtggccaagaag aaccagttggtgatcatgttgatcgatgagctgtgtggcccagacccttccctgtcggac gagctgacctccatcctcaacgagctcactcagctgagcaaaagcgagcactgcaaagtg gccctcagagcccggcagatcctgattgcctcccatctcccctcctacgagctgcggcat aaccaggtggagtccattttcctgtctgccattgacatgtacggccaccagttctgcccc gagaacctcaagaaattaatactttcggaaacaaccatctttgacgtcctgcctactttc ttctatcatgctaacaaagtcgtgtgcatggcgtccttggaggtttacgtgcggaggggc tacatcgcctatgagttaaacagcctgcagcaccggcagctcccggacggtacctgtgtg gtagaattccagttcatgctgccctcctcccacccaaaccggatgactgtgcccatcagt atcaccaaccctgacctgctgaggcacagcacagagctcttcatggacagcggcttctcc ccactgtgccagcgcatgggagccatggtagccttcaggagattcgaggacttcaccaga aattttgatgaagtcatctcttgctttgccaacgtgcccaaagacacccccctcttcagc gaggcccgcacctccctgtactccgaggatgactgcaagagcctcagagaagagcccatc cacattctgaatgtgtccatccagtgtgcagaccacctggaggatgaggcactggtgccg attttacggacgtttgtacagtccaagaaaaatatccttgtggattatggactccgacga atcacattcttgattgcccaagagaaagaatttcccaagtttttcacattcagagcaaga gatgagtttgcagaagatcgcatttaccgtcacttggaacctgccctggccttccagctg gaactcaaccggatgcgtaacttcgatctgaccgccgtgccctgtgccaaccacaagatg cacctttacctgggtgctgccaaggtgaaggaaggggtggaagtgacggaccataggttc ttcatccgcgccatcatcaggcactccgacctgattacaaaggaagcctccttcgaatac ctgcagaacgagggtgagcggctgctcctggaggccatggacgagctggaggtggcgttc aataacaccagcgtgcgaaccgactgcaaccacatcttcctcaacttcgtgcccactgtc atcatggaccccttcaagatcgaggagtccgtgcgctacatggttatgcgctacggcagc cggttgtggaaactccgcgtgctgcaggctgaggtcaagatcaacatccgccagaccacc accggcagtgccgttcccatccgcctgttcatcaccaatgagtcgggctactacctggac atcagcctctacaaagaagtgactgactccagatccggaaatatcatgtttcactccttc ggcaacaagcaagggccccagcacgggatgctgatcaatactccctacgtcaccaaggat ctgctccaggccaagcgattccaggcccagtccctgggaaccacctacatctatgacttc ccggaaatgttcaggcaggctctctttaaactgtggagctccccagacaagtatcccaaa gacatcctgacatacactgaattagtgttggactctcagggccagctggtggagatgaac cgacttcctggtggaaatgaggtgggcatggtggccttcaaaatgaggtttaagacccag gagtacccggaaggacgggacgtgatcgtcatcggcaacgacatcacctttcgcattgga tcttttggccctggggaggaccttctgtacctgcgggcatccgagatggcccgggcagag ggcattcccaaaatctacgtggcagccaacagtggcgcccgtattggcatggcagaggag atcaaacacatgttccacgtggcttgggtggacccagaagacccccacaaaggatttaaa tacctgtacctgactccccaagactacaccagaatcagctccctgaactccgtccactgt aaacacatcgaggaaggaggagaatccagatacatgatcacggatatcatcgggaaggat gatggcttgggcgtggagaatctgaggggctcaggcatgattgctggggagtcctctctg gcttacgaagagatcgtcaccattagcttggtgacctgccgagccattgggattggggcc tacttggtgaggctgggccagcgagtgatccaggtggagaactcccacatcatcctcaca ggagcaagtgctctcaacaaggtcctgggaagagaggtctacacatccaacaaccagctg ggtggcgttcagatcatgcattacaatggtgtctcccacatcaccgtgccagatgacttt gagggggtttataccatcctggagtggctgtcctatatgccaaaggataatcacagccct gtccctatcatcacaccaactgaccccattgacagagaaattgaattcctcccatccaga gctccctacgacccccggtggatgcttgcaggaaggcctcacccaactctgaagggaacg tggcagagcggattctttgaccacggcagtttcaaggaaatcatggcaccctgggcacag accgtggtaacaggacgagcaaggcttggggggattcccgtgggagtgattgctgtggag acacggactgtggaggtggcagtccctgcagaccctgccaacctggattctgaggccaag ataattcagcaggcaggacaggtgtggttcccagactcagcctacaaaactgcccaggcc atcaaggacttcaaccgggagaagttgcccctgatgatctttgccaactggagggggttc tctggtggcatgaaagacatgtatgaccaggtgctgaagtttggagcctacatcgtggac ggccttagacaatacaaacagcccatcctgatctatatcccaccctatgcggagctccgg ggaggctcctgggtggtcatagacgccaccatcaacccactgtgcatagaaatgtatgcg gacaaagagagcagggggggtgttctggaaccagaggggacagtggagattaagttccga aagaaagatctgataaagtccatgagaaggctcgatccagcttacaagaagctcatggaa cagctaggggaacctgatctctccgacaaggaccgcaaggacctggagggccggctgaaa gctcgcgaggacctgctgctccccatctaccaccaggtggcggtgcagttcgccgacttc cacgacacgcccggccggatgctggagaagggcgtcatatctgacatcctggagtggaag accgcacgcaccttcctatattggcgtctgcgccgcctcctcctggaggaccaggtcaag caggagatcctgcaggccagtggggagctgagtcacgtgcatatccagtccatgctgcgc cgctggttcgtggagacggagggggctgtcaaggcctacttgtgggacaacaaccaggtg gttgtgcagtggctggaacagcactggcaggcgggggatggcccgcgctccaccatccgt gagaacatcacgtacctgaagcacgactctgtcctcaagaccatccgaggcctggttgaa gaaaaccccgaggtggccgtggactgtgtgatatacctgagccagcacatcagcccagct gagcgggcgcaggtcgttcacctgctgtctaccatggacagcccggcctccacctga

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