KEGG   Pongo abelii (Sumatran orangutan): 100451077
Entry
100451077         CDS       T01416                                 

Gene name
FOXO3
Definition
(RefSeq) forkhead box protein O3
  KO
K09408  forkhead box protein O3
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon04062  Chemokine signaling pathway
pon04068  FoxO signaling pathway
pon04137  Mitophagy - animal
pon04151  PI3K-Akt signaling pathway
pon04152  AMPK signaling pathway
pon04211  Longevity regulating pathway
pon04213  Longevity regulating pathway - multiple species
pon04218  Cellular senescence
pon04722  Neurotrophin signaling pathway
pon04917  Prolactin signaling pathway
pon05213  Endometrial cancer
pon05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    100451077 (FOXO3)
   04151 PI3K-Akt signaling pathway
    100451077 (FOXO3)
   04152 AMPK signaling pathway
    100451077 (FOXO3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    100451077 (FOXO3)
  09143 Cell growth and death
   04218 Cellular senescence
    100451077 (FOXO3)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    100451077 (FOXO3)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    100451077 (FOXO3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100451077 (FOXO3)
  09149 Aging
   04211 Longevity regulating pathway
    100451077 (FOXO3)
   04213 Longevity regulating pathway - multiple species
    100451077 (FOXO3)
 09160 Human Diseases
  09162 Cancer: specific types
   05213 Endometrial cancer
    100451077 (FOXO3)
   05223 Non-small cell lung cancer
    100451077 (FOXO3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100451077 (FOXO3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pon03000]
    100451077 (FOXO3)
Transcription factors [BR:pon03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix other regulators
    100451077 (FOXO3)
SSDB
Motif
Pfam: FOXO_KIX_bdg Forkhead FOXO-TAD
Other DBs
NCBI-GeneID: 100451077
NCBI-ProteinID: XP_002817265
Ensembl: ENSPPYG00000016896
UniProt: A0A6D2X932 A0A2J8U1S2
LinkDB
Position
6
AA seq 672 aa
MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE
EDDEDDEDGGGRAGSAMAIGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGALSG
GTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLS
QIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGG
KSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSD
ELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKP
CTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGS
GLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSH
SDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQ
GALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPV
MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTG
AKQASSQSWVPG
NT seq 2019 nt   +upstreamnt  +downstreamnt
atggcagaggcaccggcctccccggccccgctctctccgctcgaagtggagctggacccg
gagttcgagccccagagccgtccgcgatcctgtacgtggcccctgcaaaggccggagctc
caagcgagccctgccaagccctcgggggagacggccgccgactccatgatccccgaggag
gaggacgatgaagacgacgaggacggcgggggacgggccggctcggccatggcgatcggc
ggcggcgggagcggcacgctgggctccgggctgctccttgaggactcggcccgggtgctg
gcacccggagggcaagacccggggtctgggccagccaccgcggcgggcgcgctgagcggg
ggtacacaggcgctgctgcagcctcagcaaccactgccaccgccgcagccgggggcggct
gggggctccgggcagccaaggaaatgttcgtcgcggcggaacgcctggggaaacctgtcc
tacgcggacctgatcacccgcgccatcgagagctccccggacaaacgactcactctgtcc
cagatctacgagtggatggtgcgttgcgtgccctacttcaaggataagggcgacagcaac
agctctgccggctggaagaactccatccggcacaacctgtcactgcatagtcgattcatg
cgggtccagaatgagggaactggcaagagctcttggtggatcatcaaccctgatgggggg
aagagcggaaaagccccccggcggcgggctgtctccatggacaacagcaacaagtatacc
aagagccgtggccgcgcagccaagaagaaggcagccctgcagacagcccccgaatcagct
gacgacagtccctcccagctctccaagtggcctggcagccccacgtcacgcagcagtgat
gagctggatgcgtggacggacttccgttcacgcaccaattctaacgccagcacagtcagt
ggccgcctgtcacccatcatggcaagcacagagttggatgaagtccaggacgacgatgcg
cctctctcgcccatgctctacagcagctcagccagcctgtcaccttcagtaagcaagccg
tgcacggtggaactgccacggctgactgatatggcgggcaccatgaatctgaatgatggg
ctgactgaaaacctcatggacgacctgctggataacatcacgctcccgccatcccagcca
tcgcccactgggggactcatgcagcggagctctagcttcccatataccaccaagggctca
ggcctgggctccccaaccagctcctttaacagcacggtgtttggaccttcatctctgaac
tccctacgccagtctcccatgcagaccattcaagagaacaagccagctaccttctcttcc
atgtcacactatggtaaccagacactccaggacctgctcacttcggactcacttagccac
agcgatgtcatgatgacacagtcggaccccttgatgtctcaggccagcaccgctgtgtct
gcccagaattcccgccggaacgtgatgcttcgcaatgatccgatgatgtcctttgctgcc
cagcctaaccagggaagtttggtcaatcagaacttgctccaccaccagcaccaaacccag
ggcgctcttggtggcagccgtgccttgtcgaattctgtcagcaacatgggcttgagtgag
tccagcagccttgggtcagccaaacaccagcagcagtctcctgtcagccagtctatgcaa
accctctcggactctctctcaggctcctccttgtactcaactagtgcaaacctgcccgtc
atgggccatgagaagttccccagcgacttggacctggacatgttcaatgggagcttggaa
tgtgacatggagtccattatccgtagtgaactcatggatgctgatgggttggattttaac
tttgattccctcatctccacacagaatgttgttggtttgaacgtggggaacttcactggt
gctaagcaggcctcatctcagagctgggtgccaggctga

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