Pongo abelii (Sumatran orangutan): 100459074
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Entry
100459074 CDS
T01416
Gene name
APAF1
Definition
(RefSeq) apoptotic protease-activating factor 1
KO
K02084
apoptotic protease-activating factor
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01524
Platinum drug resistance
pon04115
p53 signaling pathway
pon04210
Apoptosis
pon04215
Apoptosis - multiple species
pon05010
Alzheimer disease
pon05012
Parkinson disease
pon05014
Amyotrophic lateral sclerosis
pon05016
Huntington disease
pon05020
Prion disease
pon05022
Pathways of neurodegeneration - multiple diseases
pon05134
Legionellosis
pon05152
Tuberculosis
pon05160
Hepatitis C
pon05161
Hepatitis B
pon05162
Measles
pon05164
Influenza A
pon05168
Herpes simplex virus 1 infection
pon05169
Epstein-Barr virus infection
pon05200
Pathways in cancer
pon05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
100459074 (APAF1)
04215 Apoptosis - multiple species
100459074 (APAF1)
04115 p53 signaling pathway
100459074 (APAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100459074 (APAF1)
09162 Cancer: specific types
05222 Small cell lung cancer
100459074 (APAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100459074 (APAF1)
05012 Parkinson disease
100459074 (APAF1)
05014 Amyotrophic lateral sclerosis
100459074 (APAF1)
05016 Huntington disease
100459074 (APAF1)
05020 Prion disease
100459074 (APAF1)
05022 Pathways of neurodegeneration - multiple diseases
100459074 (APAF1)
09171 Infectious disease: bacterial
05134 Legionellosis
100459074 (APAF1)
05152 Tuberculosis
100459074 (APAF1)
09172 Infectious disease: viral
05161 Hepatitis B
100459074 (APAF1)
05160 Hepatitis C
100459074 (APAF1)
05164 Influenza A
100459074 (APAF1)
05162 Measles
100459074 (APAF1)
05168 Herpes simplex virus 1 infection
100459074 (APAF1)
05169 Epstein-Barr virus infection
100459074 (APAF1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100459074 (APAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NB-ARC
WD40
APAF1_C
ANAPC4_WD40
CARD
Ge1_WD40
eIF2A
WD40_like
CARD_2
Utp8
AAA_16
Hira
AAA_22
NACHT
AAA_18
Motif
Other DBs
NCBI-GeneID:
100459074
NCBI-ProteinID:
XP_002823669
Ensembl:
ENSPPYG00000004860
UniProt:
A0A663D9B7
H2NIC5
LinkDB
All DBs
Position
12
AA seq
1248 aa
AA seq
DB search
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
LKKDNDSYISFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
ILDDVWDSWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQSHTLSPDQEDC
MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDVTSANERKS
INVKQFFLNSEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
STIQYCDFSPQNHLAVVALSQYCVELWNIDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIKRLQLINGKTGQIDYLT
EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
SSDDSEIQVWNWQLDKYIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNTEKD
FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDHLLPLHELRGHNGCVRCSAFSVDST
LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIK
WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
NT seq
3747 nt
NT seq
+upstream
nt +downstream
nt
atggatgcaaaagctcgaaattgtttgcttcaacatagagaagctctggaaaaggacatc
aagacatcctacatcatggatcacatgattagtgatggatttttaacaatatcagaagag
gaaaaagtaagaaatgagcccactcaacagcaaagagcagctatgctaattaaaatgata
cttaaaaaagataatgattcctacatatcgttctacaatgctctactacatgaaggatat
aaagatcttgctgcccttctccatgatggcattcctgttgtctcttcttccagtggtaaa
gattcagttagtggaataacttcatatgtaaggacagtcctgtgtgaaggtggagtacca
cagaggccagttgtttttgtcacaaggaagaagctggtgaatgcgattcagcagaagctc
tccaaattgaagggtgaaccaggatgggtcaccatacatggaatggcaggctgtgggaag
tctgtattagctgcagaagctgttagagatcattcccttttagaaggttgtttcccaggg
ggagtgcactgggtttcagttgggaaacaagacaaatctgggcttctgatgaaactgcag
aatctttgcacacggttggatcaggatgagagtttttcccagaggcttccacttaatatt
gaagaggctaaagaccgtctccgcattctgatgcttcgcaaacacccaaggtctctgttg
atcttggatgatgtttgggactcttgggtgttgaaagcttttgacaatcagtgtcagatt
cttcttacaaccagagacaagagtgttacagattcagtaatgggtcctaaatatgtagtc
cctgtggagagttccttaggaaaggaaaaaggacttgaaattttatccctttttgttaat
atgaagaaggcagatttgccagaacaagctcatagtattataaaagaatgtaaaggctct
ccccttgtagtatctttaattggtgcacttttacgtgattttcccaatcgctgggagtac
tacctcaaacagcttcagaataagcagtttaagagaataaggaaatcttcgtcttatgat
tatgaggctctagatgaagccatgtctataagtgttgaaatgctcagagaagacatcaaa
gattattacacagatctttccatccttcagaaggacgttaaggtgcctacaaaggtgtta
tgtattctctgggacatggaaactgaagaagttgaagacatactgcaggagtttgtaaat
aagtctcttttattctgtgatcggaatggaaagtcgtttcgttattatttacatgatctt
caagtagattttcttacagagaagaattgcagccagcttcaggatctacataagaagata
atcactcagtttcagagatatcaccagtcgcatactctttcaccagatcaggaagactgt
atgtattggtacaactttctggcctatcacatggccagtgccaagatgcacaaggaactt
tgtgctttaatgttttccctggattggattaaagcaaagacagaacttgtaggccctgct
catctgattcatgaatttgtggaatacagacatatactagatgaaaaggattgtgcagtc
agtgagaattttcaggagtttttatctttaaatggacaccttcttggacgacagccattt
cctaatattgtacaactgggtctctgtgagccggaaacttcagaagtttatcagcaagct
aagctgcaggccaagcaggaggtcgataatggaatgctttacctggaatggataaacaaa
aaaaacatcacgaatctttcccgcttagttgtccgcccccacacagatgctgtttaccat
gcctgcttttctgaggatggtcagagaatagcttcttgtggagctgataaaaccttacag
gtgttcaaagctgaaacaggagagaaacttttagaaatcaaggctcatgaggatgaagtg
ctttgttgtgcattctctacagatgacagatttatagcaacctgctcagtggataaaaaa
gtgaagatttggaattctatgaccggggaactagtacacacctatgatgagcactcagag
caagtcaattgctgccatttcaccaacagtagtcatcatcttctcttagccactgggtca
agtgactgcttcctcaaactttgggatttgaatcaaaaagaatgtcgaaataccatgttt
ggtcatacaaattcagtcaatcactgcagattttcaccagatgataagcttttggctagt
tgttcagctgatggaaccttaaagctttgggatgtgacatcagcaaatgagaggaaaagc
attaatgtgaaacagttcttcctaaattcagaggaccctcaagaggatatggaagtgata
gtgaagtgttgctcgtggtctgctgatggtgcaaggataatggtggcagcaaaaaataaa
atcttcctttttgacattcataccagtggcctattgggagaaatccacacgggccatcac
agcaccatccagtactgtgacttctccccacaaaaccatttggcagtggttgctttgtcc
cagtactgtgtagagttgtggaatatagactcacgttcaaaggtggctgattgcagagga
catttaagttgggttcatggtgtgatgttttctcctgatggatcatcatttttgacatct
tctgatgaccagacaatcaggctctgggagacaaagaaagtatgtaagaactctgctgta
atgttaaagcaagaagtagatgttgtgtttcaagaaaatgaagtgatggtccttgcagtt
gaccatataaaacgtctgcaactcattaatggaaaaacaggtcagattgattatctgact
gaagctcaagttagctgctgttgcttaagtccacatcttcagtacattgcatttggagat
gaaaatggagccattgagattttagaacttgtaaacaatagaatcttccagtccaggttt
cagcacaagaaaactgtatggcacatccagttcacagctgatgagaagactcttatttca
agttctgatgattctgaaattcaggtatggaattggcaattggacaaatatatctttcta
cgaggccatcaggaaacagtgaaagactttagactcttgaaaaattcaagactgctctct
tggtcatttgatggaacagtgaaggtatggaatattattactggaaatacagaaaaagac
tttgtctgtcaccagggtacagtactttcttgtgacatttctcatgatgctaccaagttt
tcgtctacctctgctgacaagactgcaaagatctggagttttgatcaccttttgccactt
catgaattgaggggccacaacggctgtgtgcgctgctctgccttctctgtggacagtacc
ctactggcaaccggagatgacaatggagaaatcaggatatggaatgtctcaaacggtgag
cttcttcatttgtgtgctccgctttcagaagaaggagctgctacccatggaggctgggtg
actgacctttgcttttctccagatggcaaaatgcttatctctgctggaggatatattaag
tggtggaacgttgtcactggggaatcctcacagaccttctacacaaatggaaccaatctt
aagaaaatacatgtgtcccctgacttcaaaacatatgtgactgtggataatcttggtatt
ttatatattttacagactttagaataa
DBGET
integrated database retrieval system
