Pongo abelii (Sumatran orangutan): 100461291
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Entry
100461291 CDS
T01416
Gene name
TGFB2
Definition
(RefSeq) transforming growth factor beta-2 isoform X1
KO
K13376
transforming growth factor beta-2
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04060
Cytokine-cytokine receptor interaction
pon04068
FoxO signaling pathway
pon04110
Cell cycle
pon04218
Cellular senescence
pon04350
TGF-beta signaling pathway
pon04380
Osteoclast differentiation
pon04390
Hippo signaling pathway
pon04933
AGE-RAGE signaling pathway in diabetic complications
pon05140
Leishmaniasis
pon05142
Chagas disease
pon05144
Malaria
pon05145
Toxoplasmosis
pon05146
Amoebiasis
pon05152
Tuberculosis
pon05161
Hepatitis B
pon05166
Human T-cell leukemia virus 1 infection
pon05200
Pathways in cancer
pon05205
Proteoglycans in cancer
pon05206
MicroRNAs in cancer
pon05210
Colorectal cancer
pon05211
Renal cell carcinoma
pon05212
Pancreatic cancer
pon05220
Chronic myeloid leukemia
pon05225
Hepatocellular carcinoma
pon05226
Gastric cancer
pon05321
Inflammatory bowel disease
pon05323
Rheumatoid arthritis
pon05410
Hypertrophic cardiomyopathy
pon05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100461291 (TGFB2)
04350 TGF-beta signaling pathway
100461291 (TGFB2)
04390 Hippo signaling pathway
100461291 (TGFB2)
04068 FoxO signaling pathway
100461291 (TGFB2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100461291 (TGFB2)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100461291 (TGFB2)
04218 Cellular senescence
100461291 (TGFB2)
09150 Organismal Systems
09158 Development and regeneration
04380 Osteoclast differentiation
100461291 (TGFB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100461291 (TGFB2)
05206 MicroRNAs in cancer
100461291 (TGFB2)
05205 Proteoglycans in cancer
100461291 (TGFB2)
09162 Cancer: specific types
05210 Colorectal cancer
100461291 (TGFB2)
05212 Pancreatic cancer
100461291 (TGFB2)
05225 Hepatocellular carcinoma
100461291 (TGFB2)
05226 Gastric cancer
100461291 (TGFB2)
05220 Chronic myeloid leukemia
100461291 (TGFB2)
05211 Renal cell carcinoma
100461291 (TGFB2)
09163 Immune disease
05323 Rheumatoid arthritis
100461291 (TGFB2)
05321 Inflammatory bowel disease
100461291 (TGFB2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100461291 (TGFB2)
05414 Dilated cardiomyopathy
100461291 (TGFB2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100461291 (TGFB2)
09171 Infectious disease: bacterial
05152 Tuberculosis
100461291 (TGFB2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100461291 (TGFB2)
05161 Hepatitis B
100461291 (TGFB2)
09174 Infectious disease: parasitic
05146 Amoebiasis
100461291 (TGFB2)
05144 Malaria
100461291 (TGFB2)
05145 Toxoplasmosis
100461291 (TGFB2)
05140 Leishmaniasis
100461291 (TGFB2)
05142 Chagas disease
100461291 (TGFB2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and growth factors [BR:
pon04052
]
100461291 (TGFB2)
00536 Glycosaminoglycan binding proteins [BR:
pon00536
]
100461291 (TGFB2)
Cytokines and growth factors [BR:
pon04052
]
Cytokines
Transforming growth factors (RSTK binding)
100461291 (TGFB2)
Glycosaminoglycan binding proteins [BR:
pon00536
]
Heparan sulfate / Heparin
Growth factors/receptors
100461291 (TGFB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
SPEG_u2
Motif
Other DBs
NCBI-GeneID:
100461291
NCBI-ProteinID:
XP_002809490
Ensembl:
ENSPPYG00000000213
UniProt:
A0A2J8RS20
LinkDB
All DBs
Position
1
AA seq
442 aa
AA seq
DB search
MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLNSPPEDYPEP
EEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSETVCPV
VTTPSGSVGSLCSRQSQVLCGYLDAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVF
RLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLH
HKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRK
KNSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW
KWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILY
YIGKTPKIEQLSNMIVKSCKCS
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgcactactgtgtgctgagcgcttttctgatcctgcatctggtcacggtcgcgctcagc
ctgtctacctgcagcacactcgatatggaccagttcatgcgcaagaggatcgaggcgatc
cgcgggcagatcctgagcaagctgaagctcaacagtcccccagaagactatcctgagcct
gaggaagtccccccggaggtgatttccatctacaacagcaccagggacttgctccaggag
aaggcgagccggagggcggccgcctgcgagcgcgagaggagcgacgaagagtactacgcc
aaggaggtttacaaaatagacatgccgcccttcttcccctccgaaactgtctgcccagtt
gttacaacaccctctggctcagtgggcagcttgtgctccagacagtcccaggtgctctgt
gggtaccttgatgccatcccgcccactttctacagaccttacttcagaattgttcgattt
gacgtctcagcaatggagaagaatgcttccaatttggtgaaagcagagttcagagtcttt
cgtttgcagaacccaaaagccagagtgcctgaacaacggattgagctgtatcagattctc
aagtccaaagatttaacatctccaacccagcgctacattgacagcaaagttgtgaaaaca
agagcagaaggcgaatggctctccttcgatgtaactgatgctgttcatgaatggcttcac
cataaagacaggaacctgggatttaaaataagcttacactgtccctgctgcacttttgta
ccatctaataattacatcatcccaaataaaagcgaagaactagaagcaagatttgcaggt
attgatggcacctccacatataccagtggtgatcagaaaactataaagtccactaggaaa
aaaaacagtgggaagaccccacatctcctgctaatgttattgccctcctacagacttgag
tcacaacagaccaaccggcggaagaagcgtgctttggatgcggcctattgctttagaaat
gtgcaggataattgctgcctacgtccactttacattgatttcaagagggatctagggtgg
aaatggatacacgaacccaaagggtacaatgccaacttctgtgctggagcatgcccgtat
ttatggagttcagacactcagcacagcagggtcctgagcttatataataccataaatcca
gaagcatctgcttctccttgctgcgtgtcccaagatttagaacctctaaccattctctac
tacattggaaaaacacccaagattgaacagctttctaatatgattgtaaagtcttgcaaa
tgcagctaa
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