Komagataella phaffii: PAS_chr2-2_0168
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Entry
PAS_chr2-2_0168 CDS
T01092
Name
(RefSeq) Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme
KO
K05824
homoisocitrate dehydrogenase [EC:
1.1.1.87
]
Organism
ppa
Komagataella phaffii
Pathway
ppa00300
Lysine biosynthesis
ppa01100
Metabolic pathways
ppa01110
Biosynthesis of secondary metabolites
ppa01210
2-Oxocarboxylic acid metabolism
ppa01230
Biosynthesis of amino acids
Module
ppa_M00030
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
ppa_M00433
Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
Brite
KEGG Orthology (KO) [BR:
ppa00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PAS_chr2-2_0168
Enzymes [BR:
ppa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.87 homoisocitrate dehydrogenase
PAS_chr2-2_0168
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
8198271
NCBI-ProteinID:
XP_002492036
UniProt:
C4R2N2
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Position
2:2071465..2072577
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AA seq
370 aa
AA seq
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MLSAVRNNVRSYSTAVKTLKIGLIPGDGIGREVIPAGKQILEALPAEHGLKFEFQNLDAG
FELFKKTGVALPDATVEALKQNCDGALFGAVSSPTTKVEGYSSPIVALRKKMGLYANVRP
VKSVEGIGRPVDMVIVRENTEDLYIKEERVYEKDGQKIAEAIKRISENATNKIGKMALEI
ALQRQAVRELGGTSLHSKPSLTVTHKSNVLALSDGLFRETIKKLYDSNSKYASIEYKEQI
VDSMVYRMFREPEIFDVVVAPNLYGDILSDGAAALVGSLGVVPSANVGDDFAIGEPCHGS
APDIEGKGISNPVATIRSTALMLEFMGYPKAAAQIYAAVDSNLAEDKIKTPDLNGKSTTQ
EVVDDIIRRF
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atgctgtcagctgtcagaaacaacgtccgtagctattccactgctgttaaaaccttgaaa
attggtttgatcccaggagatggaattggaagagaggttatacctgctggaaaacaaatt
ttggaggctctcccagctgaacatggtctgaaatttgaattccaaaatttggatgccggt
ttcgaattgttcaagaagaccggtgtagctcttccagatgctaccgtggaagccttgaag
caaaactgcgacggtgctcttttcggtgccgtttcctctccaactactaaggtagaaggg
tactcttctcctattgttgccttgagaaagaagatgggactctacgccaacgtccgtcct
gtgaaatctgttgaaggtattggtagaccagttgatatggttattgttcgtgagaacact
gaagatttgtatattaaggaggagagagtgtacgagaaggacggtcagaaaatagcagaa
gctatcaagcgtatctctgaaaatgccaccaacaaaattggtaaaatggctctggagatc
gccttgcaaagacaagctgtccgtgaattaggaggaacttctttacattctaaaccttct
cttactgttactcataaatctaacgttttggctctatctgatggtttgttccgtgagact
atcaagaaactctacgacagtaactccaagtacgcttctatcgagtataaggagcaaatt
gttgactcaatggtctacagaatgttccgtgaacctgaaatctttgacgtagtcgttgca
cctaacttgtatggtgacattctttctgatggtgctgcggccttagttgggtccttaggg
gttgttccttctgctaacgttggtgatgattttgccatcggtgagccatgtcacggatct
gccccagatatcgaaggtaaaggtatttccaatccggtcgctaccattagatccactgct
ctcatgctggagttcatgggttaccctaaggctgctgctcaaatctatgctgctgttgat
tctaatcttgctgaggacaagattaagactcctgatttgaatggaaagtccactactcaa
gaagttgtggacgatatcattagacgtttttaa
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