Panthera pardus (leopard): 109250950 Help Entry 109250950         CDS       T06062                                  Symbol PSEN2 Name (RefSeq) presenilin-2 isoform X1   KO K04522   presenilin 2 [EC:3.4.23.-] Organism ppad  Panthera pardus (leopard) Pathway ppad04330   Notch signaling pathway ppad04722   Neurotrophin signaling pathway ppad05010   Alzheimer disease ppad05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:ppad00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     109250950 (PSEN2)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     109250950 (PSEN2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     109250950 (PSEN2)    05022 Pathways of neurodegeneration - multiple diseases     109250950 (PSEN2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ppad01002]     109250950 (PSEN2) Peptidases and inhibitors [BR:ppad01002]  Aspartic peptidases   Family A22: presenilin family    109250950 (PSEN2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Presenilin Motif Other DBs NCBI-GeneID:  109250950 NCBI-ProteinID:  XP_019277700 Ensembl:  ENSPPRG00000002017 LinkDB All DBs Position Unknown AA seq 518 aa AA seqDB search MDRSQDRVSGMSVFLQLETSTANRSLWKSFIIFLGQILRSGISGPKGASRGRAMLTFMAS DSEEEVCDERASLMSAESPPPRCCQEDRQGLEDGEGADQWRGQDSEDDFDEDPDHYVCGG VPGQPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLPYGAGREQ SLQPAVSLSIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKYRCYKFIHG WLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQA YLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFP ALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPGYPGD DLEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFK KALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI NT seq 1557 nt NT seq  +upstreamnt  +downstreamnt atggacaggtcccaggacagggtttctggcatgtcagtgtttttacagttagaaacgtcc acagcaaacaggtctttatggaaatcttttattattttcttaggacaaattctgagaagt ggcatttcaggaccaaaaggcgcttcccgaggcagggccatgctcacgttcatggcctct gacagcgaggaggaagtgtgtgacgagagggcgtccctgatgtcagccgagagcccccca ccacgctgctgccaggaggacaggcagggcttggaggatggagagggtgctgaccagtgg agaggccaggatagcgaggacgactttgacgaggaccctgaccactacgtctgcgggggg gtcccggggcagccgtcaggcctggaggaggagctgaccctgaaatacggggcgaagcac gtgatcatgctgttcgtgccggtgacgctgtgcatgatcgtggtggtggccaccatcaag tccgtgcgcttctacacggagaagaacggacagctgccctatggagcaggcagggagcag agtctgcagcccgccgtctccctcagcatctacacaccattcaccgaggacacgccctcc gtgggccagcgcctcctcaactccgtgctcaacaccctcatcatgatcagtgtcattgtg gccatgaccatcttcttggtcgtgctctacaaataccgctgctacaagtttatacacggc tggttgatcatgtcctcgctgatgctgcttttcctcttcacctacatctacctcggggag gtgctcaagacctacaacgtggccatggactaccccacgctgttcctgacggtctggaac ttcggggcggtgggcatggtgtgtatccactggaagggccccctggtcctgcagcaagcc tacctcatcatgatcagcgccctcatggccctggtgttcatcaagtaccttccggagtgg tccgcgtgggtcatcctgggtgccatctccgtgtacgatctcgtggctgtgctgtgcccc aaagggccactgagaatgctggtggaaacggcccaggagagaaacgagcccatattccct gccctgatatactcctccgccatggtgtggacggtgggcatggccaagctggacccctcc tcccagggagcccttcagctgccctacgacccagagatggaggaagactcctatgacagt tttggtgagccctcgtaccccgaagtctttgagcccccgctgcctggttaccccggggac gacctggaggaagaggaggaaaggggcgtgaagctcggcctgggggacttcatcttctac agcgtgctggtgggcaaggcggcggccacgggcagcggcgactggaacacgacgctggcg tgctttgtggccatcctcattggtctgtgtctgaccctcctgctgctggccgtgttcaag aaggcgctgcccgccctccccatctccatcaccttcggcctcatcttttacttctccacg gacaacctggtgcgccctttcatggacaccttggcctcacatcagctctacatctga

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