Panthera pardus (leopard): 109263111
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Entry
109263111 CDS
T06062
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00564
Glycerophospholipid metabolism
ppad00565
Ether lipid metabolism
ppad00590
Arachidonic acid metabolism
ppad00591
Linoleic acid metabolism
ppad00592
alpha-Linolenic acid metabolism
ppad01100
Metabolic pathways
ppad04010
MAPK signaling pathway
ppad04014
Ras signaling pathway
ppad04072
Phospholipase D signaling pathway
ppad04217
Necroptosis
ppad04270
Vascular smooth muscle contraction
ppad04370
VEGF signaling pathway
ppad04611
Platelet activation
ppad04664
Fc epsilon RI signaling pathway
ppad04666
Fc gamma R-mediated phagocytosis
ppad04724
Glutamatergic synapse
ppad04726
Serotonergic synapse
ppad04730
Long-term depression
ppad04750
Inflammatory mediator regulation of TRP channels
ppad04912
GnRH signaling pathway
ppad04913
Ovarian steroidogenesis
ppad04921
Oxytocin signaling pathway
ppad05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
109263111 (PLA2G4E)
00565 Ether lipid metabolism
109263111 (PLA2G4E)
00590 Arachidonic acid metabolism
109263111 (PLA2G4E)
00591 Linoleic acid metabolism
109263111 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
109263111 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109263111 (PLA2G4E)
04014 Ras signaling pathway
109263111 (PLA2G4E)
04370 VEGF signaling pathway
109263111 (PLA2G4E)
04072 Phospholipase D signaling pathway
109263111 (PLA2G4E)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
109263111 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
109263111 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
109263111 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
109263111 (PLA2G4E)
09152 Endocrine system
04912 GnRH signaling pathway
109263111 (PLA2G4E)
04913 Ovarian steroidogenesis
109263111 (PLA2G4E)
04921 Oxytocin signaling pathway
109263111 (PLA2G4E)
09153 Circulatory system
04270 Vascular smooth muscle contraction
109263111 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
109263111 (PLA2G4E)
04726 Serotonergic synapse
109263111 (PLA2G4E)
04730 Long-term depression
109263111 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
109263111 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
109263111 (PLA2G4E)
Enzymes [BR:
ppad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
109263111 (PLA2G4E)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
109263111
NCBI-ProteinID:
XP_019298014
Ensembl:
ENSPPRG00000013329
UniProt:
A0A9V1F8R3
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MTLQSSEGCPGLGTDVFAPKELQGAEESRSERNVSEFEHTQDLETPSLPPLLPTALGGSQ
GGVSPCHLLTVKVIRMKNVRQADMVSQTDCFVSLWLPTASRERLRTRTISNCPNPEWNET
FSFQIQSQVKNVLELSICDEDTVTPNDHLLTVLYDLTKLCFRKKTHMKFPLNPEGMEELE
VEFLLEESPFPPETLVTNGVLVSRQVSCLEVHAECRRQKKSRKMKDLLVTVKESFEHTQR
VSHCQEPCCLNLACFHYPKYFQPRMHVEVPKSQWRCGPCCCCARKNSPVCQPLDCLPDGQ
AVTLPVGENCELHVKSTPCPQTLDVRLGFSLCQAELEFLQKRKVVVAEALKQVLQLEEDL
HTDEVPLIAIMATGGGARSMTAMYGHLLGLQKLNILNCASYITGLSGATWTMATLYRDPD
WSSKNLEPAIFEARRHVVKDKMPALFPDQLCKFQEELRQRSQEGYKVTFTDFWGLLIEAC
LGDERNECKLSDQRAALSQGQNPLPIYLTINVKDDVSNQDFREWCEFSPYEVGLQKYGAF
IPTELFGSEFFMGRLMKRIPESRMCYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTRDK
VHDIEDEPLLPEIPKCDANILDTAVVIPGSWLSNTFRSILTHRSFVSEFHNFLLGLQLHN
DYLQNSQFSMWRDTVLDTFPNQLTGSVNHLCLLDTAFFVNSSYPPLLRPERKVDLIIHLN
YCAGSQTKPMKQTCEYCSVQNIPFPKYEVQEGDENLKECYLIENSQEPDAPIVIFFPLIN
DTFQKYKAPGVERSPEELEQGHVDIYGPKTPYATKELTYTEAAFDKLVKLSEYNILNNKD
KLFQALRLAVEKKKRLKSQCPS
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgactctccagagctcggaaggctgtcctggcctgggaactgatgtgtttgccccaaag
gagctacagggggctgaagagagcaggtcagaaagaaatgtcagtgagtttgagcacaca
caggacctggaaactcccagtctcccacctctgcttcccacggcccttgggggctctcag
ggtggggtctctccatgccacctgctgacagtgaaggtcatccggatgaaaaatgtccgg
caggctgatatggtgagccagacagactgctttgtgagcctttggctgcccactgcttct
cgtgaaaggctgaggactaggaccatctccaactgcccaaacccagagtggaatgaaacc
ttcagcttccagatccaaagccaagtgaagaacgtgctggagctgagcatctgtgatgaa
gacacagtgacaccaaatgaccacctgttgacagtcctctatgacctcaccaagctctgc
ttccgaaagaaaacccatatgaagttcccactcaacccagagggcatggaagagctggag
gtagagttcctgctggaggagagtccctttccacctgagaccctcgtcaccaacggcgtg
ctggtgtctcgacaagtctcctgcttagaggttcatgcagaatgcaggaggcagaagaag
agcaggaaaatgaaggacctcctggtgacagtaaaggagtccttcgagcacacccagcgc
gtctcgcactgccaggagccctgctgcctgaacctggcctgcttccactaccccaagtac
ttccagccccggatgcacgtggaagtgcccaagagccagtggagatgtgggccctgctgc
tgctgtgcgcgcaagaacagccctgtctgccagcccctcgattgccttcctgacggccag
gcggtgaccctgccggtgggtgagaattgtgagttacacgtgaagtctacaccctgcccc
cagacgcttgacgtgcggctgggcttcagcctatgccaggcagagctggagtttctgcag
aagcggaaggtggtggtggccgaggcactgaaacaggtgttgcagctggaggaggacctg
catacggacgaggtaccattgatagccatcatggccactgggggtggagcaagatccatg
accgccatgtatggccacctgctggggctgcagaagctgaacatcctgaactgtgccagc
tacatcactggcctgtcaggggccacctggaccatggctaccttgtaccgtgatcctgac
tggtcctccaaaaacctggagccggccatatttgaggcacggaggcatgtggtcaaggac
aagatgcctgccctattcccagaccagctctgcaaattccaggaggagcttcggcagcgc
agtcaggaaggctacaaggtcacctttacagatttctggggccttctgattgaggcctgt
ctgggggatgagagaaatgaatgcaaactgtcagatcagcgtgctgctttatcccagggc
cagaaccccctgcccatctacctcaccatcaatgtcaaggatgatgtaagcaaccaggat
ttcagagagtggtgcgagttctccccctacgaagtgggcctgcagaagtacggcgccttc
atccccactgagctcttcggatccgagttcttcatggggcggctgatgaaaaggatccca
gagtcaaggatgtgctacatgctaggtttgtggagcagcatcttctccctgaacttgctc
gatgcctggaatctgtcccatacctcagaggagtttttccacaggtggacgagggataaa
gtgcacgacatcgaagatgagccactcctgcctgaaatccccaaatgtgatgccaacatc
ttggacaccgcggtggtgatcccagggtcctggttgtccaatactttccgcagcatcctc
acccataggtccttcgtgtctgagttccacaacttcctgttggggctgcagctgcacaac
gactacctccagaacagccagttctccatgtggagagacacggtgctagatactttcccg
aaccagctgacggggtccgtgaaccacttgtgcctgttggacactgcattctttgtcaat
tccagctacccgcccctccttaggcctgagagaaaagtcgacctcatcatccacctcaat
tactgtgctgggtcccagacaaagcccatgaaacaaacctgtgagtactgctctgtgcag
aatatccccttccccaaatacgaagtgcaagaaggggacgaaaatctcaaggagtgctac
ctgatagagaactcccaagaacctgatgctcccatcgtgattttcttcccactcatcaat
gacaccttccagaagtacaaggccccaggtgtggagaggagccccgaggagctggagcag
ggccatgttgacatttatggccccaaaactccgtatgctacgaaggagctgacatacaca
gaggccgcctttgacaagctggtgaagctctctgagtacaacatcctgaataacaaagac
aagctctttcaggccttgagactcgcggtggagaagaagaaacgcctgaagagccagtgt
ccctcctaa
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