Pan paniscus (bonobo): 100969217 Help Entry 100969217         CDS       T02283                                  Gene name AKT3 Definition (RefSeq) AKT serine/threonine kinase 3   KO K04456   RAC serine/threonine-protein kinase [EC:2.7.11.1] Organism pps  Pan paniscus (bonobo) Pathway pps01521   EGFR tyrosine kinase inhibitor resistance pps01522   Endocrine resistance pps01524   Platinum drug resistance pps04010   MAPK signaling pathway pps04012   ErbB signaling pathway pps04014   Ras signaling pathway pps04015   Rap1 signaling pathway pps04022   cGMP-PKG signaling pathway pps04024   cAMP signaling pathway pps04062   Chemokine signaling pathway pps04066   HIF-1 signaling pathway pps04068   FoxO signaling pathway pps04071   Sphingolipid signaling pathway pps04072   Phospholipase D signaling pathway pps04140   Autophagy - animal pps04150   mTOR signaling pathway pps04151   PI3K-Akt signaling pathway pps04152   AMPK signaling pathway pps04210   Apoptosis pps04211   Longevity regulating pathway pps04213   Longevity regulating pathway - multiple species pps04218   Cellular senescence pps04261   Adrenergic signaling in cardiomyocytes pps04370   VEGF signaling pathway pps04371   Apelin signaling pathway pps04380   Osteoclast differentiation pps04510   Focal adhesion pps04550   Signaling pathways regulating pluripotency of stem cells pps04611   Platelet activation pps04613   Neutrophil extracellular trap formation pps04620   Toll-like receptor signaling pathway pps04625   C-type lectin receptor signaling pathway pps04630   JAK-STAT signaling pathway pps04660   T cell receptor signaling pathway pps04662   B cell receptor signaling pathway pps04664   Fc epsilon RI signaling pathway pps04666   Fc gamma R-mediated phagocytosis pps04668   TNF signaling pathway pps04722   Neurotrophin signaling pathway pps04725   Cholinergic synapse pps04728   Dopaminergic synapse pps04910   Insulin signaling pathway pps04914   Progesterone-mediated oocyte maturation pps04915   Estrogen signaling pathway pps04917   Prolactin signaling pathway pps04919   Thyroid hormone signaling pathway pps04920   Adipocytokine signaling pathway pps04922   Glucagon signaling pathway pps04923   Regulation of lipolysis in adipocytes pps04926   Relaxin signaling pathway pps04929   GnRH secretion pps04931   Insulin resistance pps04932   Non-alcoholic fatty liver disease pps04933   AGE-RAGE signaling pathway in diabetic complications pps04935   Growth hormone synthesis, secretion and action pps04973   Carbohydrate digestion and absorption pps05010   Alzheimer disease pps05017   Spinocerebellar ataxia pps05132   Salmonella infection pps05135   Yersinia infection pps05142   Chagas disease pps05145   Toxoplasmosis pps05152   Tuberculosis pps05160   Hepatitis C pps05161   Hepatitis B pps05162   Measles pps05163   Human cytomegalovirus infection pps05164   Influenza A pps05165   Human papillomavirus infection pps05166   Human T-cell leukemia virus 1 infection pps05167   Kaposi sarcoma-associated herpesvirus infection pps05168   Herpes simplex virus 1 infection pps05169   Epstein-Barr virus infection pps05170   Human immunodeficiency virus 1 infection pps05200   Pathways in cancer pps05205   Proteoglycans in cancer pps05210   Colorectal cancer pps05211   Renal cell carcinoma pps05212   Pancreatic cancer pps05213   Endometrial cancer pps05214   Glioma pps05215   Prostate cancer pps05218   Melanoma pps05220   Chronic myeloid leukemia pps05221   Acute myeloid leukemia pps05222   Small cell lung cancer pps05223   Non-small cell lung cancer pps05224   Breast cancer pps05225   Hepatocellular carcinoma pps05226   Gastric cancer pps05230   Central carbon metabolism in cancer pps05231   Choline metabolism in cancer pps05235   PD-L1 expression and PD-1 checkpoint pathway in cancer pps05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:pps00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100969217 (AKT3)    04012 ErbB signaling pathway     100969217 (AKT3)    04014 Ras signaling pathway     100969217 (AKT3)    04015 Rap1 signaling pathway     100969217 (AKT3)    04370 VEGF signaling pathway     100969217 (AKT3)    04371 Apelin signaling pathway     100969217 (AKT3)    04630 JAK-STAT signaling pathway     100969217 (AKT3)    04668 TNF signaling pathway     100969217 (AKT3)    04066 HIF-1 signaling pathway     100969217 (AKT3)    04068 FoxO signaling pathway     100969217 (AKT3)    04072 Phospholipase D signaling pathway     100969217 (AKT3)    04071 Sphingolipid signaling pathway     100969217 (AKT3)    04024 cAMP signaling pathway     100969217 (AKT3)    04022 cGMP-PKG signaling pathway     100969217 (AKT3)    04151 PI3K-Akt signaling pathway     100969217 (AKT3)    04152 AMPK signaling pathway     100969217 (AKT3)    04150 mTOR signaling pathway     100969217 (AKT3)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100969217 (AKT3)   09143 Cell growth and death    04210 Apoptosis     100969217 (AKT3)    04218 Cellular senescence     100969217 (AKT3)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100969217 (AKT3)    04550 Signaling pathways regulating pluripotency of stem cells     100969217 (AKT3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100969217 (AKT3)    04613 Neutrophil extracellular trap formation     100969217 (AKT3)    04620 Toll-like receptor signaling pathway     100969217 (AKT3)    04625 C-type lectin receptor signaling pathway     100969217 (AKT3)    04660 T cell receptor signaling pathway     100969217 (AKT3)    04662 B cell receptor signaling pathway     100969217 (AKT3)    04664 Fc epsilon RI signaling pathway     100969217 (AKT3)    04666 Fc gamma R-mediated phagocytosis     100969217 (AKT3)    04062 Chemokine signaling pathway     100969217 (AKT3)   09152 Endocrine system    04910 Insulin signaling pathway     100969217 (AKT3)    04922 Glucagon signaling pathway     100969217 (AKT3)    04923 Regulation of lipolysis in adipocytes     100969217 (AKT3)    04920 Adipocytokine signaling pathway     100969217 (AKT3)    04929 GnRH secretion     100969217 (AKT3)    04915 Estrogen signaling pathway     100969217 (AKT3)    04914 Progesterone-mediated oocyte maturation     100969217 (AKT3)    04917 Prolactin signaling pathway     100969217 (AKT3)    04926 Relaxin signaling pathway     100969217 (AKT3)    04935 Growth hormone synthesis, secretion and action     100969217 (AKT3)    04919 Thyroid hormone signaling pathway     100969217 (AKT3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100969217 (AKT3)   09154 Digestive system    04973 Carbohydrate digestion and absorption     100969217 (AKT3)   09156 Nervous system    04725 Cholinergic synapse     100969217 (AKT3)    04728 Dopaminergic synapse     100969217 (AKT3)    04722 Neurotrophin signaling pathway     100969217 (AKT3)   09158 Development and regeneration    04380 Osteoclast differentiation     100969217 (AKT3)   09149 Aging    04211 Longevity regulating pathway     100969217 (AKT3)    04213 Longevity regulating pathway - multiple species     100969217 (AKT3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100969217 (AKT3)    05205 Proteoglycans in cancer     100969217 (AKT3)    05230 Central carbon metabolism in cancer     100969217 (AKT3)    05231 Choline metabolism in cancer     100969217 (AKT3)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100969217 (AKT3)   09162 Cancer: specific types    05210 Colorectal cancer     100969217 (AKT3)    05212 Pancreatic cancer     100969217 (AKT3)    05225 Hepatocellular carcinoma     100969217 (AKT3)    05226 Gastric cancer     100969217 (AKT3)    05214 Glioma     100969217 (AKT3)    05221 Acute myeloid leukemia     100969217 (AKT3)    05220 Chronic myeloid leukemia     100969217 (AKT3)    05218 Melanoma     100969217 (AKT3)    05211 Renal cell carcinoma     100969217 (AKT3)    05215 Prostate cancer     100969217 (AKT3)    05213 Endometrial cancer     100969217 (AKT3)    05224 Breast cancer     100969217 (AKT3)    05222 Small cell lung cancer     100969217 (AKT3)    05223 Non-small cell lung cancer     100969217 (AKT3)   09164 Neurodegenerative disease    05010 Alzheimer disease     100969217 (AKT3)    05017 Spinocerebellar ataxia     100969217 (AKT3)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     100969217 (AKT3)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     100969217 (AKT3)    04931 Insulin resistance     100969217 (AKT3)    04933 AGE-RAGE signaling pathway in diabetic complications     100969217 (AKT3)   09171 Infectious disease: bacterial    05132 Salmonella infection     100969217 (AKT3)    05135 Yersinia infection     100969217 (AKT3)    05152 Tuberculosis     100969217 (AKT3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100969217 (AKT3)    05170 Human immunodeficiency virus 1 infection     100969217 (AKT3)    05161 Hepatitis B     100969217 (AKT3)    05160 Hepatitis C     100969217 (AKT3)    05164 Influenza A     100969217 (AKT3)    05162 Measles     100969217 (AKT3)    05168 Herpes simplex virus 1 infection     100969217 (AKT3)    05163 Human cytomegalovirus infection     100969217 (AKT3)    05167 Kaposi sarcoma-associated herpesvirus infection     100969217 (AKT3)    05169 Epstein-Barr virus infection     100969217 (AKT3)    05165 Human papillomavirus infection     100969217 (AKT3)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100969217 (AKT3)    05142 Chagas disease     100969217 (AKT3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100969217 (AKT3)    01524 Platinum drug resistance     100969217 (AKT3)    01522 Endocrine resistance     100969217 (AKT3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pps01001]     100969217 (AKT3) Enzymes [BR:pps01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100969217 (AKT3) Protein kinases [BR:pps01001]  Serine/threonine kinases: AGC group   AKT/PKB family    100969217 (AKT3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like FTA2 PH_11 Motif Other DBs NCBI-GeneID:  100969217 NCBI-ProteinID:  XP_003808050 UniProt:  A0A2R9BCQ8 LinkDB All DBs Position 1 AA seq 479 aa AA seqDB search MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa aactggaggccaagatacttccttttgaagacagatggctcattcataggatataaagag aaacctcaagatgtggatttaccttatcccctcaacaacttttcagtggcaaaatgccaa ttaatgaaaacagaacgaccaaagccaaacacatttataatcagatgtctccagtggacc actgttatagagagaacatttcatgtagatactccagaggaaagggaagaatggacagaa gctatccaggctgtagcggacagactgcagaggcaagaagaggagagaatgaattgtagt ccaacttcacaaattgataatataggagaggaagagatggatgcctctacaacccatcat aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg aaagttattttggttcgagagaaggcaagtggaaaatattatgctatgaagattctgaag aaagaagtcattattgcaaaggatgaagtggcacacactctaactgaaagcagagtatta aagaacactagacatccctttttaacatccttgaaatattccttccagacaaaagaccgt ttgtgttttgtgatggaatatgttaatgggggcgagctgtttttccatttgtcgagagag cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac tatctacattccggaaagattgtgtaccgtgatctcaagttggagaatctaatgctggac aaagatggccacataaaaattacagattttggactttgcaaagaagggatcacagatgca gccaccatgaagacattctgtggcactccagaatatctggcaccagaggtgttagaagat aatgactatggccgagcagtagactggtggggcctaggggttgtcatgtatgaaatgatg tgtgggaggttacctttctacaaccaggaccatgagaaactttttgaattaatattaatg gaagacattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc ttgataaaggatccaaataaacgccttggtggaggaccagatgatgcaaaagaaattatg agacacagtttcttctctggagtaaactggcaagatgtatatgataaaaagcttgtacct ccttttaaacctcaagtaacatctgagacagatactagatattttgatgaagaatttaca gctcagactattacaataacaccacctgaaaaatatgatgaggatggtatggactgcatg gacaatgagaggcggccgcatttccctcaattttcctactctgcaagtggacgagaataa

Pan paniscus (bonobo): 100969444 Help Entry 100969444         CDS       T02283                                  Gene name AKT1 Definition (RefSeq) AKT serine/threonine kinase 1   KO K04456   RAC serine/threonine-protein kinase [EC:2.7.11.1] Organism pps  Pan paniscus (bonobo) Pathway pps01521   EGFR tyrosine kinase inhibitor resistance pps01522   Endocrine resistance pps01524   Platinum drug resistance pps04010   MAPK signaling pathway pps04012   ErbB signaling pathway pps04014   Ras signaling pathway pps04015   Rap1 signaling pathway pps04022   cGMP-PKG signaling pathway pps04024   cAMP signaling pathway pps04062   Chemokine signaling pathway pps04066   HIF-1 signaling pathway pps04068   FoxO signaling pathway pps04071   Sphingolipid signaling pathway pps04072   Phospholipase D signaling pathway pps04140   Autophagy - animal pps04150   mTOR signaling pathway pps04151   PI3K-Akt signaling pathway pps04152   AMPK signaling pathway pps04210   Apoptosis pps04211   Longevity regulating pathway pps04213   Longevity regulating pathway - multiple species pps04218   Cellular senescence pps04261   Adrenergic signaling in cardiomyocytes pps04370   VEGF signaling pathway pps04371   Apelin signaling pathway pps04380   Osteoclast differentiation pps04510   Focal adhesion pps04550   Signaling pathways regulating pluripotency of stem cells pps04611   Platelet activation pps04613   Neutrophil extracellular trap formation pps04620   Toll-like receptor signaling pathway pps04625   C-type lectin receptor signaling pathway pps04630   JAK-STAT signaling pathway pps04660   T cell receptor signaling pathway pps04662   B cell receptor signaling pathway pps04664   Fc epsilon RI signaling pathway pps04666   Fc gamma R-mediated phagocytosis pps04668   TNF signaling pathway pps04722   Neurotrophin signaling pathway pps04725   Cholinergic synapse pps04728   Dopaminergic synapse pps04910   Insulin signaling pathway pps04914   Progesterone-mediated oocyte maturation pps04915   Estrogen signaling pathway pps04917   Prolactin signaling pathway pps04919   Thyroid hormone signaling pathway pps04920   Adipocytokine signaling pathway pps04922   Glucagon signaling pathway pps04923   Regulation of lipolysis in adipocytes pps04926   Relaxin signaling pathway pps04929   GnRH secretion pps04931   Insulin resistance pps04932   Non-alcoholic fatty liver disease pps04933   AGE-RAGE signaling pathway in diabetic complications pps04935   Growth hormone synthesis, secretion and action pps04973   Carbohydrate digestion and absorption pps05010   Alzheimer disease pps05017   Spinocerebellar ataxia pps05132   Salmonella infection pps05135   Yersinia infection pps05142   Chagas disease pps05145   Toxoplasmosis pps05152   Tuberculosis pps05160   Hepatitis C pps05161   Hepatitis B pps05162   Measles pps05163   Human cytomegalovirus infection pps05164   Influenza A pps05165   Human papillomavirus infection pps05166   Human T-cell leukemia virus 1 infection pps05167   Kaposi sarcoma-associated herpesvirus infection pps05168   Herpes simplex virus 1 infection pps05169   Epstein-Barr virus infection pps05170   Human immunodeficiency virus 1 infection pps05200   Pathways in cancer pps05205   Proteoglycans in cancer pps05210   Colorectal cancer pps05211   Renal cell carcinoma pps05212   Pancreatic cancer pps05213   Endometrial cancer pps05214   Glioma pps05215   Prostate cancer pps05218   Melanoma pps05220   Chronic myeloid leukemia pps05221   Acute myeloid leukemia pps05222   Small cell lung cancer pps05223   Non-small cell lung cancer pps05224   Breast cancer pps05225   Hepatocellular carcinoma pps05226   Gastric cancer pps05230   Central carbon metabolism in cancer pps05231   Choline metabolism in cancer pps05235   PD-L1 expression and PD-1 checkpoint pathway in cancer pps05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:pps00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100969444 (AKT1)    04012 ErbB signaling pathway     100969444 (AKT1)    04014 Ras signaling pathway     100969444 (AKT1)    04015 Rap1 signaling pathway     100969444 (AKT1)    04370 VEGF signaling pathway     100969444 (AKT1)    04371 Apelin signaling pathway     100969444 (AKT1)    04630 JAK-STAT signaling pathway     100969444 (AKT1)    04668 TNF signaling pathway     100969444 (AKT1)    04066 HIF-1 signaling pathway     100969444 (AKT1)    04068 FoxO signaling pathway     100969444 (AKT1)    04072 Phospholipase D signaling pathway     100969444 (AKT1)    04071 Sphingolipid signaling pathway     100969444 (AKT1)    04024 cAMP signaling pathway     100969444 (AKT1)    04022 cGMP-PKG signaling pathway     100969444 (AKT1)    04151 PI3K-Akt signaling pathway     100969444 (AKT1)    04152 AMPK signaling pathway     100969444 (AKT1)    04150 mTOR signaling pathway     100969444 (AKT1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100969444 (AKT1)   09143 Cell growth and death    04210 Apoptosis     100969444 (AKT1)    04218 Cellular senescence     100969444 (AKT1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100969444 (AKT1)    04550 Signaling pathways regulating pluripotency of stem cells     100969444 (AKT1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100969444 (AKT1)    04613 Neutrophil extracellular trap formation     100969444 (AKT1)    04620 Toll-like receptor signaling pathway     100969444 (AKT1)    04625 C-type lectin receptor signaling pathway     100969444 (AKT1)    04660 T cell receptor signaling pathway     100969444 (AKT1)    04662 B cell receptor signaling pathway     100969444 (AKT1)    04664 Fc epsilon RI signaling pathway     100969444 (AKT1)    04666 Fc gamma R-mediated phagocytosis     100969444 (AKT1)    04062 Chemokine signaling pathway     100969444 (AKT1)   09152 Endocrine system    04910 Insulin signaling pathway     100969444 (AKT1)    04922 Glucagon signaling pathway     100969444 (AKT1)    04923 Regulation of lipolysis in adipocytes     100969444 (AKT1)    04920 Adipocytokine signaling pathway     100969444 (AKT1)    04929 GnRH secretion     100969444 (AKT1)    04915 Estrogen signaling pathway     100969444 (AKT1)    04914 Progesterone-mediated oocyte maturation     100969444 (AKT1)    04917 Prolactin signaling pathway     100969444 (AKT1)    04926 Relaxin signaling pathway     100969444 (AKT1)    04935 Growth hormone synthesis, secretion and action     100969444 (AKT1)    04919 Thyroid hormone signaling pathway     100969444 (AKT1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100969444 (AKT1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     100969444 (AKT1)   09156 Nervous system    04725 Cholinergic synapse     100969444 (AKT1)    04728 Dopaminergic synapse     100969444 (AKT1)    04722 Neurotrophin signaling pathway     100969444 (AKT1)   09158 Development and regeneration    04380 Osteoclast differentiation     100969444 (AKT1)   09149 Aging    04211 Longevity regulating pathway     100969444 (AKT1)    04213 Longevity regulating pathway - multiple species     100969444 (AKT1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100969444 (AKT1)    05205 Proteoglycans in cancer     100969444 (AKT1)    05230 Central carbon metabolism in cancer     100969444 (AKT1)    05231 Choline metabolism in cancer     100969444 (AKT1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100969444 (AKT1)   09162 Cancer: specific types    05210 Colorectal cancer     100969444 (AKT1)    05212 Pancreatic cancer     100969444 (AKT1)    05225 Hepatocellular carcinoma     100969444 (AKT1)    05226 Gastric cancer     100969444 (AKT1)    05214 Glioma     100969444 (AKT1)    05221 Acute myeloid leukemia     100969444 (AKT1)    05220 Chronic myeloid leukemia     100969444 (AKT1)    05218 Melanoma     100969444 (AKT1)    05211 Renal cell carcinoma     100969444 (AKT1)    05215 Prostate cancer     100969444 (AKT1)    05213 Endometrial cancer     100969444 (AKT1)    05224 Breast cancer     100969444 (AKT1)    05222 Small cell lung cancer     100969444 (AKT1)    05223 Non-small cell lung cancer     100969444 (AKT1)   09164 Neurodegenerative disease    05010 Alzheimer disease     100969444 (AKT1)    05017 Spinocerebellar ataxia     100969444 (AKT1)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     100969444 (AKT1)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     100969444 (AKT1)    04931 Insulin resistance     100969444 (AKT1)    04933 AGE-RAGE signaling pathway in diabetic complications     100969444 (AKT1)   09171 Infectious disease: bacterial    05132 Salmonella infection     100969444 (AKT1)    05135 Yersinia infection     100969444 (AKT1)    05152 Tuberculosis     100969444 (AKT1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100969444 (AKT1)    05170 Human immunodeficiency virus 1 infection     100969444 (AKT1)    05161 Hepatitis B     100969444 (AKT1)    05160 Hepatitis C     100969444 (AKT1)    05164 Influenza A     100969444 (AKT1)    05162 Measles     100969444 (AKT1)    05168 Herpes simplex virus 1 infection     100969444 (AKT1)    05163 Human cytomegalovirus infection     100969444 (AKT1)    05167 Kaposi sarcoma-associated herpesvirus infection     100969444 (AKT1)    05169 Epstein-Barr virus infection     100969444 (AKT1)    05165 Human papillomavirus infection     100969444 (AKT1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100969444 (AKT1)    05142 Chagas disease     100969444 (AKT1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100969444 (AKT1)    01524 Platinum drug resistance     100969444 (AKT1)    01522 Endocrine resistance     100969444 (AKT1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pps01001]     100969444 (AKT1) Enzymes [BR:pps01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100969444 (AKT1) Protein kinases [BR:pps01001]  Serine/threonine kinases: AGC group   AKT/PKB family    100969444 (AKT1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_11 Seadorna_VP7 Pkinase_fungal APH Motif Other DBs NCBI-GeneID:  100969444 NCBI-ProteinID:  XP_003807047 UniProt:  A0A2R9BZ66 LinkDB All DBs Position 14 AA seq 480 aa AA seqDB search MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA NT seq 1443 nt NT seq  +upstreamnt  +downstreamnt atgagcgacgtggctattgtgaaggagggctggctgcacaaacgaggggagtacatcaag acctggcggccacgctacttcctcctcaagaatgatggcaccttcattggctacaaggag cggccgcaggatgtggaccaacgtgaggcccccctcaacaacttctctgtggcgcagtgc cagctgatgaagacggagcggcctcggcccaacaccttcatcatccgctgcctgcagtgg accactgtcatcgaacgcaccttccatgtggagactcctgaggagcgggaggagtggaca accgccatccagactgtggccgacggcctcaagaagcaggaggaggaggagatggacttc cggtcgggctcacccagtgacaactcaggggctgaagagatggaggtgtccctggccaag cccaagcaccgcgtgaccatgaacgagtttgagtacctgaagctgctgggcaagggcact ttcggcaaggtgatcctggtgaaggagaaggccacaggccgctactacgccatgaagatc ctcaagaaggaagtcatcgtggccaaggacgaggtggcccacacactcaccgagaaccgc gtcctgcagaactccaggcaccccttcctcacagccctgaagtactctttccagacccac gaccgcctctgcttcgtcatggagtacgccaacgggggcgagctgttcttccacctgtcc cgggagcgtgtgttctccgaggaccgggcccgcttctatggcgctgagatcgtgtcagcc ctggactacctgcactcggagaagaacgtggtgtaccgggacctcaagctggagaacctc atgctggacaaggacgggcacattaagatcacagacttcgggctgtgcaaggaggggatc aaggacggtgccaccatgaagaccttttgtggcacacccgagtacctggcccccgaggtg ctggaggacaatgactacggccgtgcagtggactggtgggggctgggcgtggtcatgtac gagatgatgtgcggccgcctgcccttctacaaccaggaccatgagaagctttttgagctc atcctcatggaggagatccgcttcccgcgcacgcttggtcccgaggccaagtccttgctt tcggggctgctcaagaaggaccccaagcagaggcttggcgggggctccgaggacgccaag gagatcatgcagcatcgcttctttgccggtatcgtgtggcagcacgtgtacgagaagaag ctcagcccacccttcaagccccaggtcacatcggagactgacaccaggtattttgatgag gagttcacggcccagatgatcaccatcacaccacctgaccaagatgacagcatggagtgt gtggacagcgagcgcaggccccacttcccccagttctcctactcggccagcggcacggcc tga

Pan paniscus (bonobo): 100991804 Help Entry 100991804         CDS       T02283                                  Gene name AKT2 Definition (RefSeq) AKT serine/threonine kinase 2   KO K04456   RAC serine/threonine-protein kinase [EC:2.7.11.1] Organism pps  Pan paniscus (bonobo) Pathway pps01521   EGFR tyrosine kinase inhibitor resistance pps01522   Endocrine resistance pps01524   Platinum drug resistance pps04010   MAPK signaling pathway pps04012   ErbB signaling pathway pps04014   Ras signaling pathway pps04015   Rap1 signaling pathway pps04022   cGMP-PKG signaling pathway pps04024   cAMP signaling pathway pps04062   Chemokine signaling pathway pps04066   HIF-1 signaling pathway pps04068   FoxO signaling pathway pps04071   Sphingolipid signaling pathway pps04072   Phospholipase D signaling pathway pps04140   Autophagy - animal pps04150   mTOR signaling pathway pps04151   PI3K-Akt signaling pathway pps04152   AMPK signaling pathway pps04210   Apoptosis pps04211   Longevity regulating pathway pps04213   Longevity regulating pathway - multiple species pps04218   Cellular senescence pps04261   Adrenergic signaling in cardiomyocytes pps04370   VEGF signaling pathway pps04371   Apelin signaling pathway pps04380   Osteoclast differentiation pps04510   Focal adhesion pps04550   Signaling pathways regulating pluripotency of stem cells pps04611   Platelet activation pps04613   Neutrophil extracellular trap formation pps04620   Toll-like receptor signaling pathway pps04625   C-type lectin receptor signaling pathway pps04630   JAK-STAT signaling pathway pps04660   T cell receptor signaling pathway pps04662   B cell receptor signaling pathway pps04664   Fc epsilon RI signaling pathway pps04666   Fc gamma R-mediated phagocytosis pps04668   TNF signaling pathway pps04722   Neurotrophin signaling pathway pps04725   Cholinergic synapse pps04728   Dopaminergic synapse pps04910   Insulin signaling pathway pps04914   Progesterone-mediated oocyte maturation pps04915   Estrogen signaling pathway pps04917   Prolactin signaling pathway pps04919   Thyroid hormone signaling pathway pps04920   Adipocytokine signaling pathway pps04922   Glucagon signaling pathway pps04923   Regulation of lipolysis in adipocytes pps04926   Relaxin signaling pathway pps04929   GnRH secretion pps04931   Insulin resistance pps04932   Non-alcoholic fatty liver disease pps04933   AGE-RAGE signaling pathway in diabetic complications pps04935   Growth hormone synthesis, secretion and action pps04973   Carbohydrate digestion and absorption pps05010   Alzheimer disease pps05017   Spinocerebellar ataxia pps05132   Salmonella infection pps05135   Yersinia infection pps05142   Chagas disease pps05145   Toxoplasmosis pps05152   Tuberculosis pps05160   Hepatitis C pps05161   Hepatitis B pps05162   Measles pps05163   Human cytomegalovirus infection pps05164   Influenza A pps05165   Human papillomavirus infection pps05166   Human T-cell leukemia virus 1 infection pps05167   Kaposi sarcoma-associated herpesvirus infection pps05168   Herpes simplex virus 1 infection pps05169   Epstein-Barr virus infection pps05170   Human immunodeficiency virus 1 infection pps05200   Pathways in cancer pps05205   Proteoglycans in cancer pps05210   Colorectal cancer pps05211   Renal cell carcinoma pps05212   Pancreatic cancer pps05213   Endometrial cancer pps05214   Glioma pps05215   Prostate cancer pps05218   Melanoma pps05220   Chronic myeloid leukemia pps05221   Acute myeloid leukemia pps05222   Small cell lung cancer pps05223   Non-small cell lung cancer pps05224   Breast cancer pps05225   Hepatocellular carcinoma pps05226   Gastric cancer pps05230   Central carbon metabolism in cancer pps05231   Choline metabolism in cancer pps05235   PD-L1 expression and PD-1 checkpoint pathway in cancer pps05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:pps00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100991804 (AKT2)    04012 ErbB signaling pathway     100991804 (AKT2)    04014 Ras signaling pathway     100991804 (AKT2)    04015 Rap1 signaling pathway     100991804 (AKT2)    04370 VEGF signaling pathway     100991804 (AKT2)    04371 Apelin signaling pathway     100991804 (AKT2)    04630 JAK-STAT signaling pathway     100991804 (AKT2)    04668 TNF signaling pathway     100991804 (AKT2)    04066 HIF-1 signaling pathway     100991804 (AKT2)    04068 FoxO signaling pathway     100991804 (AKT2)    04072 Phospholipase D signaling pathway     100991804 (AKT2)    04071 Sphingolipid signaling pathway     100991804 (AKT2)    04024 cAMP signaling pathway     100991804 (AKT2)    04022 cGMP-PKG signaling pathway     100991804 (AKT2)    04151 PI3K-Akt signaling pathway     100991804 (AKT2)    04152 AMPK signaling pathway     100991804 (AKT2)    04150 mTOR signaling pathway     100991804 (AKT2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100991804 (AKT2)   09143 Cell growth and death    04210 Apoptosis     100991804 (AKT2)    04218 Cellular senescence     100991804 (AKT2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100991804 (AKT2)    04550 Signaling pathways regulating pluripotency of stem cells     100991804 (AKT2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100991804 (AKT2)    04613 Neutrophil extracellular trap formation     100991804 (AKT2)    04620 Toll-like receptor signaling pathway     100991804 (AKT2)    04625 C-type lectin receptor signaling pathway     100991804 (AKT2)    04660 T cell receptor signaling pathway     100991804 (AKT2)    04662 B cell receptor signaling pathway     100991804 (AKT2)    04664 Fc epsilon RI signaling pathway     100991804 (AKT2)    04666 Fc gamma R-mediated phagocytosis     100991804 (AKT2)    04062 Chemokine signaling pathway     100991804 (AKT2)   09152 Endocrine system    04910 Insulin signaling pathway     100991804 (AKT2)    04922 Glucagon signaling pathway     100991804 (AKT2)    04923 Regulation of lipolysis in adipocytes     100991804 (AKT2)    04920 Adipocytokine signaling pathway     100991804 (AKT2)    04929 GnRH secretion     100991804 (AKT2)    04915 Estrogen signaling pathway     100991804 (AKT2)    04914 Progesterone-mediated oocyte maturation     100991804 (AKT2)    04917 Prolactin signaling pathway     100991804 (AKT2)    04926 Relaxin signaling pathway     100991804 (AKT2)    04935 Growth hormone synthesis, secretion and action     100991804 (AKT2)    04919 Thyroid hormone signaling pathway     100991804 (AKT2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100991804 (AKT2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     100991804 (AKT2)   09156 Nervous system    04725 Cholinergic synapse     100991804 (AKT2)    04728 Dopaminergic synapse     100991804 (AKT2)    04722 Neurotrophin signaling pathway     100991804 (AKT2)   09158 Development and regeneration    04380 Osteoclast differentiation     100991804 (AKT2)   09149 Aging    04211 Longevity regulating pathway     100991804 (AKT2)    04213 Longevity regulating pathway - multiple species     100991804 (AKT2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100991804 (AKT2)    05205 Proteoglycans in cancer     100991804 (AKT2)    05230 Central carbon metabolism in cancer     100991804 (AKT2)    05231 Choline metabolism in cancer     100991804 (AKT2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100991804 (AKT2)   09162 Cancer: specific types    05210 Colorectal cancer     100991804 (AKT2)    05212 Pancreatic cancer     100991804 (AKT2)    05225 Hepatocellular carcinoma     100991804 (AKT2)    05226 Gastric cancer     100991804 (AKT2)    05214 Glioma     100991804 (AKT2)    05221 Acute myeloid leukemia     100991804 (AKT2)    05220 Chronic myeloid leukemia     100991804 (AKT2)    05218 Melanoma     100991804 (AKT2)    05211 Renal cell carcinoma     100991804 (AKT2)    05215 Prostate cancer     100991804 (AKT2)    05213 Endometrial cancer     100991804 (AKT2)    05224 Breast cancer     100991804 (AKT2)    05222 Small cell lung cancer     100991804 (AKT2)    05223 Non-small cell lung cancer     100991804 (AKT2)   09164 Neurodegenerative disease    05010 Alzheimer disease     100991804 (AKT2)    05017 Spinocerebellar ataxia     100991804 (AKT2)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     100991804 (AKT2)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     100991804 (AKT2)    04931 Insulin resistance     100991804 (AKT2)    04933 AGE-RAGE signaling pathway in diabetic complications     100991804 (AKT2)   09171 Infectious disease: bacterial    05132 Salmonella infection     100991804 (AKT2)    05135 Yersinia infection     100991804 (AKT2)    05152 Tuberculosis     100991804 (AKT2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100991804 (AKT2)    05170 Human immunodeficiency virus 1 infection     100991804 (AKT2)    05161 Hepatitis B     100991804 (AKT2)    05160 Hepatitis C     100991804 (AKT2)    05164 Influenza A     100991804 (AKT2)    05162 Measles     100991804 (AKT2)    05168 Herpes simplex virus 1 infection     100991804 (AKT2)    05163 Human cytomegalovirus infection     100991804 (AKT2)    05167 Kaposi sarcoma-associated herpesvirus infection     100991804 (AKT2)    05169 Epstein-Barr virus infection     100991804 (AKT2)    05165 Human papillomavirus infection     100991804 (AKT2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100991804 (AKT2)    05142 Chagas disease     100991804 (AKT2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100991804 (AKT2)    01524 Platinum drug resistance     100991804 (AKT2)    01522 Endocrine resistance     100991804 (AKT2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pps01001]     100991804 (AKT2) Enzymes [BR:pps01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100991804 (AKT2) Protein kinases [BR:pps01001]  Serine/threonine kinases: AGC group   AKT/PKB family    100991804 (AKT2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PH Kinase-like Pkinase_C Motif Other DBs NCBI-GeneID:  100991804 NCBI-ProteinID:  XP_003812539 UniProt:  A0A2R9A1U2 LinkDB All DBs Position 19 AA seq 481 aa AA seqDB search MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM DYKCGSPSDSSMAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR E NT seq 1446 nt NT seq  +upstreamnt  +downstreamnt atgaacgaggtgtctgtcatcaaagaaggctggctccacaagcgtggtgaatacatcaag acctggaggccacggtacttcctgctgaagagcgacggctccttcattgggtacaaggag aggcccgaggcccctgatcagactctaccccccttaaacaacttctccgtagcagaatgc cagctgatgaagaccgagaggccgcgacccaacacctttgtcatacgctgcctgcagtgg accacagtcatcgagaggaccttccacgtggattctccagatgagagggaggaatggatg cgggccatccagatggtcgccaacagcctcaagcagcgggccccaggcgaggaccccatg gactacaagtgtggctcccccagtgactcctctatggctgaggagatggaagtggcggtc agcaaggcacgggctaaagtgaccatgaatgacttcgactatctcaaactccttggcaag ggaacctttggcaaagtcatcctggtgcgggagaaggccactggccgctactacgccatg aagatcctgcggaaggaagtcatcattgccaaggatgaagtcgctcacacagtcaccgag agccgagtcctccagaacaccaggcacccgttcctcactgcgctgaagtacgccttccag acccacgaccgcctgtgctttgtgatggagtatgccaacgggggtgagctgttcttccac ctgtcccgggagcgtgtcttcacagaggagcgggcccggttttatggtgcagagattgtc tcggctcttgagtacttgcactcacgggacgtggtataccgcgacatcaagctggaaaac ctcatgctggacaaagatggccacatcaagatcactgactttggcctctgcaaagagggc atcagtgacggggccaccatgaaaaccttctgtgggaccccggagtacctggcgcctgag gtgctggaggacaatgactatggccgggccgtggactggtgggggctgggtgtggtcatg tacgagatgatgtgcggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag ctcatcctcatggaagagatccgcttcccgcgcacgctcagccccgaggccaagtccctg cttgctgggctgcttaagaaggaccccaagcagaggcttggtggggggcccagcgatgcc aaggaggtcatggagcacaggttcttcctcagcatcaactggcaggacgtggtccagaag aagctcctgccacccttcaaacctcaggtcacgtccgaggtcgacacaaggtacttcgat gatgaatttaccgcccagtccatcacaatcacaccccctgaccgctatgacagcctgggc ttactggagctggaccagcggacccacttcccccagttctcctactcggccagcatccgg gagtga

DBGET integrated database retrieval system