Pan paniscus (bonobo): 100978497 Help Entry 100978497         CDS       T02283                                  Gene name CASP8 Definition (RefSeq) caspase 8   KO K04398   caspase 8 [EC:3.4.22.61] Organism pps  Pan paniscus (bonobo) Pathway pps01524   Platinum drug resistance pps04115   p53 signaling pathway pps04210   Apoptosis pps04215   Apoptosis - multiple species pps04217   Necroptosis pps04620   Toll-like receptor signaling pathway pps04621   NOD-like receptor signaling pathway pps04622   RIG-I-like receptor signaling pathway pps04625   C-type lectin receptor signaling pathway pps04657   IL-17 signaling pathway pps04668   TNF signaling pathway pps04932   Non-alcoholic fatty liver disease pps05010   Alzheimer disease pps05016   Huntington disease pps05022   Pathways of neurodegeneration - multiple diseases pps05132   Salmonella infection pps05134   Legionellosis pps05142   Chagas disease pps05145   Toxoplasmosis pps05152   Tuberculosis pps05160   Hepatitis C pps05161   Hepatitis B pps05162   Measles pps05163   Human cytomegalovirus infection pps05164   Influenza A pps05165   Human papillomavirus infection pps05167   Kaposi sarcoma-associated herpesvirus infection pps05168   Herpes simplex virus 1 infection pps05169   Epstein-Barr virus infection pps05170   Human immunodeficiency virus 1 infection pps05200   Pathways in cancer pps05203   Viral carcinogenesis pps05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:pps00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     100978497 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100978497 (CASP8)    04215 Apoptosis - multiple species     100978497 (CASP8)    04217 Necroptosis     100978497 (CASP8)    04115 p53 signaling pathway     100978497 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100978497 (CASP8)    04621 NOD-like receptor signaling pathway     100978497 (CASP8)    04622 RIG-I-like receptor signaling pathway     100978497 (CASP8)    04625 C-type lectin receptor signaling pathway     100978497 (CASP8)    04657 IL-17 signaling pathway     100978497 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100978497 (CASP8)    05203 Viral carcinogenesis     100978497 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     100978497 (CASP8)    05016 Huntington disease     100978497 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     100978497 (CASP8)   09166 Cardiovascular disease    05416 Viral myocarditis     100978497 (CASP8)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     100978497 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     100978497 (CASP8)    05134 Legionellosis     100978497 (CASP8)    05152 Tuberculosis     100978497 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100978497 (CASP8)    05161 Hepatitis B     100978497 (CASP8)    05160 Hepatitis C     100978497 (CASP8)    05164 Influenza A     100978497 (CASP8)    05162 Measles     100978497 (CASP8)    05168 Herpes simplex virus 1 infection     100978497 (CASP8)    05163 Human cytomegalovirus infection     100978497 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     100978497 (CASP8)    05169 Epstein-Barr virus infection     100978497 (CASP8)    05165 Human papillomavirus infection     100978497 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100978497 (CASP8)    05142 Chagas disease     100978497 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100978497 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pps01002]     100978497 (CASP8) Enzymes [BR:pps01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      100978497 (CASP8) Peptidases and inhibitors [BR:pps01002]  Cysteine peptidases   Family C14: caspase family    100978497 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  100978497 NCBI-ProteinID:  XP_003820791 UniProt:  A0A2R9AJC1 LinkDB All DBs Position 2B AA seq 464 aa AA seqDB search MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINRSLLKIINDYEE FSKGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLH SIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVQQIYEILKIYQLMDHSNMDCFICCIL SHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDS EEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPR GDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD NT seq 1395 nt NT seq  +upstreamnt  +downstreamnt atggacttcagcagaaatctttatgatattggggaacaactggacagtgaagatctggcc tccctcaagttcctgagcctggactacattccgcaaaggaagcaagaacccatcaaggat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaatctgtcc ttcctgaaggagctgctcttccgaattaatagactggatttgctgattacctacctaaac actagaaaggaggagatggaaagggaacttcagacaccaggcagggctcaaatttctgcc tacagggtcatgctgtatcagatttcagaagaagtgagcagatcagaattgaggtctttt aagtttcttttgcaagaggaaatctccaaatgcaaactggatgatgacatgaacctgctg gatattttcatagagatggagaagagggtcatcctgggagaaggaaagttggacatcctg aaaagagtctgtgcccaaatcaacaggagcctgctgaagataatcaacgactatgaagaa ttcagcaaaggggaggagttgtgtggggtaatgacaatctcggactctccaagagaacag gatagtgaatcacagactttggacaaagtttaccaaatgaaaagcaaacctcggggatac tgtctgatcatcaacaatcacaattttgcaaaagcacgggagaaagtgcccaaacttcac agtattagggacaggaatggaacacacttggatgcaggggctttgaccacgacctttgaa gagcttcattttgagatcaagccccacgatgactgcacggtacagcaaatctatgagatt ttgaaaatctaccaactcatggaccacagtaacatggactgcttcatctgctgtatcctc tcccatggagacaagggcatcatctacggcactgatggacaggaggcccccatctatgag ctgacatctcagttcactggtttgaagtgcccttcccttgctggaaaacccaaagtgttt tttattcaggcttgtcagggggataactaccagaaaggtatacctgttgagactgattca gaggagcaaccctatttagaaatggatttatcatcacctcaaacgagatatatcccggat gaggctgactttctgctggggatggccactgtgaataactgtgtttcctaccgaaaccct gcagagggaacctggtacatccagtcactttgccagagcctgagagagcgatgtcctcga ggcgatgatattctcaccatcctgactgaagtgaactatgaagtaagcaacaaggatgac aagaaaaacatggggaaacagatgcctcagcctactttcacattaagaaaaaaacttgtc ttcccttctgattga

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