Poecilia reticulata (guppy): 103459734 Help Entry 103459734         CDS       T05149                                  Gene name irs2 Definition (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism pret  Poecilia reticulata (guppy) Pathway pret04068   FoxO signaling pathway pret04140   Autophagy - animal pret04910   Insulin signaling pathway pret04920   Adipocytokine signaling pathway Brite KEGG Orthology (KO) [BR:pret00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103459734 (irs2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103459734 (irs2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103459734 (irs2)    04920 Adipocytokine signaling pathway     103459734 (irs2) Domain-containing proteins not elsewhere classified [BR:pret04990]  Phosphotyrosine binding (PTB) domain-containing proteins   IRS related family proteins    103459734 (irs2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 PH_8 Mcp5_PH Motif Other DBs NCBI-GeneID:  103459734 NCBI-ProteinID:  XP_008399768 UniProt:  A0A3P9QHR0 LinkDB All DBs Position LG2 AA seq 1110 aa AA seqDB search MASPPTTGGQALMTSTSNTNANNSAKKCGYLKKQKHGHKRFFVLKEPCEGFPARLEYYEN EKKWRNKSAAKRVVPLDCCLNVSKRADAKHKYLIALYTKDEYFAVAAENEQEQENWYRAL TDLMAEGKVCDGSASNSASSLVGFDETSYGVITPVAAAYKEVWQVNLKSRGLGQSRNLTG VYRLCLSSRMISFVKLNSEVASVVLQLMNIRRCGHSDSFFFIEVGRSAAIGPGELWMQAD DSVVAQNIHETILEAMKAMKELSEFRPRSKSQSSSTNPISVPTRRHLNNLPPSQTGLPRR SRTDSTCATSPVSSKCLSCRIRTASEGDGTMTRPMSVTGSPLSPGVHRTILSRSHTVTAR PSLTFESSTLQHSKSMSMPLSHSPPVATPCPGHVSNCVDSSVPRPSSCSASFSGSPSDAG FISCEEYGSSPADARDLRLPLTLRSNTPESLKADTPPSRDGSELDGYMVMERQNQNGYRR LSELDKVYRKRTYSLTTPRQQRRPPQVSSASLDEYTLMRATYTSGSRSSLRCHTASPKGS GLEDYRDVHISSNSLHGDSGYMPMMPGVAPQTPGSKDDPYMPMSPMCVSAPKQIINPRSH SCTAGLAPRTDSPGSISLEDNGYMPMWCGHKMSVESSDGKPSNGEYLYMSPVDALVSLTP PEYLLSLSGDPHPHHRQPYCYSSLPRLVKGQLQRTGSADTDQYVVMSLQRQRIEEESNGG PVSPGESGTGSSPGTPTTPSSLPSLKLTRSDGGMLHRSRVCRPTRLALESLRTLPCMSEH PLPSEPRSPGEYINIDFGSSADVPLLESSEAGNVMCKEEGSLSLSDYANIDINSSVHLES HQGEGSHPAGRLNHTSEVLMCSSMVSNQQDTQRVEGKEDEKRTEGETKTMGQKGSPVCEP AITKSDYTEMTFGPSAPLSVLCTSDATPLPTSPTACVKRLSLESSLVDVVPPVPVDSFLL GAPSLSLTVVDPDRGAKVIRADPQGRRRHSSETFSSTTTVTPVCPSFAHDTKRHSSASVE NVSRSVHSSEEPGEDHSSPMCRETSAGYQNGLNYIALNLMEGNLGGGRLGACDEFLRFKT TCGCKGGLNGFSASPYASLGFKETTTAVKE NT seq 3333 nt NT seq  +upstreamnt  +downstreamnt atggcgagtccgccaaccacgggcggtcaggcgctgatgaccagcactagtaatacaaac gccaataacagcgcgaaaaaatgtggatacctgaagaagcagaaacacggacacaagcgt tttttcgttttaaaggagccgtgtgaaggattccctgcccggctggagtactacgagaac gagaagaaatggagaaacaagtccgcggctaagagagttgttcccctggactgctgcctc aacgtcagcaagagagcggacgcgaaacacaagtatctcattgctctttacaccaaggac gagtattttgccgtggcggcggaaaacgagcaggaacaggagaactggtaccgggcgctg acggacctaatggccgaggggaaagtgtgtgacggctcggcgtccaactctgcgtcttca ctggttggcttcgacgagacgagttacggtgtaataacgccggtggccgccgcctacaag gaggtatggcaggttaacctcaaatccaggggactgggacagagtaggaatctgaccggt gtgtacaggctctgtctctccagccgaatgatcagcttcgttaagctcaactcggaggtc gcctctgtcgtactacagctgatgaacatccgaaggtgcggccattccgacagctttttc ttcattgaggtgggtcgatctgcagccatcggtccaggggaactgtggatgcaagctgat gactcagtagtggctcagaatatccacgaaactatcctagaggccatgaaagccatgaag gagctgtcggagttccgcccgcgcagcaaaagtcagtcatctagcaccaaccccatctct gtgccaacaaggaggcatctgaataatcttccaccgagccagaccggcctcccccggagg tcccgtactgacagcacctgtgccacatctcctgtgagtagtaaatgcctgtcttgtcgt atacgcacggccagcgagggcgatggcaccatgacacgcccaatgtctgtcaccgggagc cccctcagcccaggggtccacaggaccatcctgagccggtctcacaccgtaacagcacgc ccctccttgacttttgaatcttctactctccagcatagtaagtccatgtctatgcccctg tctcattctccgcctgtggccaccccatgcccaggacatgtttccaactgtgtggacagc agtgtcccccgcccctccagctgcagtgcatcattctcaggctctcccagtgatgcaggc tttatatcatgtgaagaatatggctccagtcctgctgatgcacgggacctcaggttaccc ctaacccttcgcagcaacactcctgaatctctgaaagcagacacccctccctccagggat gggagtgaacttgatggctacatggtgatggagaggcaaaatcagaatggttaccggcgg ctgtcagagctggataaagtgtatcgaaagcgaacatactccctcactaccccccgtcag cagaggcgtccccctcaggtgtcctcagcttctctggatgaatacactctcatgagggcc acatacaccagtggaagccggtcttctttgaggtgtcacacggcctcacctaaaggaagc gggctagaagattacagggatgttcacatcagctctaacagtctccatggtgacagcggc tacatgccaatgatgcccggagttgcaccccagactccagggtccaaggacgacccctac atgcccatgagtcctatgtgtgtttctgctccaaagcagatcatcaatccacgttcacac tcctgcaccgcagggttggccccacgcacagactcccctgggagtatttctctggaggac aatggctacatgcctatgtggtgcggacacaagatgtcagtggaaagcagtgatggaaag ccaagcaatggagagtacctgtacatgtctcccgttgatgctctggtttctctcacaccc ccagagtaccttctcagcctctcaggagacccacacccccaccacagacagccttattgt tacagctccctaccaagattagtcaaaggacagttgcagcgaactgggtctgctgacact gaccagtatgttgtaatgagtttacagagacaacggatagaagaagagtcaaacggtggt cccgtttcacctggagaatctggaaccggtagctccccaggtacgccaaccactccatct tctctcccttctctaaaactgactcggtcagatggaggaatgttgcaccgcagcagggtg tgccggcccacccgcctggctctggaatcccttcgaacactaccatgtatgagtgagcat ccccttccctcagaacctcgcagccctggagagtacatcaacattgattttggtagttct gccgacgtcccactgttggagagctcagaggctggaaacgtaatgtgtaaagaggaggga tcactgtctctgtcagactatgctaacattgacatcaactcatcggttcatctcgaatca caccaaggagaaggttcccacccagcagggcgtcttaaccatacatctgaagtcttgatg tgctccagcatggtgagcaaccagcaggacacacagagagttgaagggaaggaggatgaa aagagaacggagggagagacaaagacaatgggacagaaagggagtcctgtatgtgagcct gctattaccaaaagtgactacactgagatgacctttggtccctctgctcctttatctgtt ctctgcaccagtgatgccacccctctccccaccagccccactgcatgtgtgaagagactc agccttgaaagcagcttagtggatgtggtgccccctgtgccagtggattctttcctactt ggggcaccatcgttatctctcactgtcgtagatccagaccggggggccaaggttatccgg gctgaccctcaggggcgtcgacgccatagctccgagaccttctcctccaccaccactgtg acgcccgtgtgcccgtctttcgcccatgataccaagcggcacagctccgcttctgtggag aacgtgtcccgctctgtccacagctccgaggagcccggcgaggaccacagcagccccatg tgcagggaaacgtcagctgggtatcaaaacggactgaactacattgccttaaacttgatg gaagggaacctcggcgggggcaggttaggcgcatgcgacgaattcctgagattcaagacg acttgcggctgcaaagggggtctaaatgggttcagcgccagcccctacgccagcctggga ttcaaggagactactactgctgtgaaagaatga

Poecilia reticulata (guppy): 103474601 Help Entry 103474601         CDS       T05149                                  Definition (RefSeq) insulin receptor substrate 2-B-like   KO K07187   insulin receptor substrate 2 Organism pret  Poecilia reticulata (guppy) Pathway pret04068   FoxO signaling pathway pret04140   Autophagy - animal pret04910   Insulin signaling pathway pret04920   Adipocytokine signaling pathway Brite KEGG Orthology (KO) [BR:pret00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103474601  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103474601  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103474601    04920 Adipocytokine signaling pathway     103474601 Domain-containing proteins not elsewhere classified [BR:pret04990]  Phosphotyrosine binding (PTB) domain-containing proteins   IRS related family proteins    103474601 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  103474601 NCBI-ProteinID:  XP_008423930 LinkDB All DBs Position LG2 AA seq 606 aa AA seqDB search MSEGHDSSTKRGFAEPPCTPRSSHHRSLTCAGESPLQFQLKNRHTEQDEEEDSNESPSSR CFEELFCTKETPIPLAPLPCALMDASGPQGDVVKEGYLGKLERSHRRYFVLRTGSYTGPS RLEWYKNQEKFTAMEKSVGKAALFGTSKQGVIYLRCCLGVSRSGSSRKGHMVVLYDKDQT LVLVMEEQQQQEDWYLAIKRLVEDEQRDEEHEEGFDEDDDGYCTLPPAAFFKEVWPVMVK PRGLGSSKLFTGENRLCLTASTLVMVRLGSSNDLPSVTIPLLSVRRFGHLDGFFFLELGR SAPHGPGEIWMEAGEEGNPVLAQHIHESVRETVRSLRALPDFTRSLTSSPNQQPALLASK RRRPKQRDKLANMRTLTPRVLHPRNSESQTSPAQHHRRAQTPEDTKSESSLSFTLHLSPA RPQQNPAPETKSRTIQSWESAEKEEGFGYMMMSPTVSHSLSELPQDDYVVMESPQKLNWP GYCSSSSSSSLQTSFSSSTCDSFSPLHPSRLQSSDISRQCCPGTPENVPSSMETSFSAQP QQAQDFDRSFLIPPFLLSGSGTKKPPQSSPNADTSQFSRPQPEQEQVRRHWLTGCLFSCF QTGEKS NT seq 1821 nt NT seq  +upstreamnt  +downstreamnt atgtcggaggggcatgatagttctaccaaaaggggatttgcagagcctccatgcacccct cggtcatcacatcaccgcagcctcacttgtgcaggtgaatctcctttgcagtttcagctg aagaatcgacacacagagcaggatgaagaggaggactcaaatgaatcgccttcatcccgc tgctttgaggagctgttctgcactaaagagaccccaatacccctggcccccctaccctgt gctttaatggacgcctcagggccgcaaggtgacgtggtgaaagaaggttacctggggaag ctggagcggagccacaggagatatttcgtcctgcgaacgggaagttacaccggtccgagc agactggagtggtacaagaaccaggagaagttcacggctatggagaagtctgttgggaag gccgctctgtttggaaccagcaaacaaggggtcatttatcttcgttgctgtcttggtgtg agtcggagtggcagttcccgaaaaggccacatggtggtgctgtacgacaaggatcagact ctggtgctggtgatggaggagcagcagcaacaggaagattggtacctggccataaagagg ctagtggaggatgagcagagggatgaggagcatgaagaagggttcgatgaagacgatgac gggtactgcactctaccgcctgcagcgttcttcaaagaggtttggccggtcatggtgaag cccagaggcctgggctcctccaaactgttcacgggggagaaccgtctctgcctcacagca tcaacacttgttatggtccggctggggtccagtaatgacttgccatcagtcacgatacct ttgctgagtgttcgccgctttggacacctggatggctttttctttttggagctgggcagg tcggcgcctcatggtcccggagaaatctggatggaggctggagaagaaggaaacccagtt ctggcccaacacatccacgagtcggttcgggagactgtgagatccctacgagctcttcca gacttcaccagatctctgacatccagtcccaatcaacagccagcccttctggcctcaaag cgccgccgacccaaacagagagacaagctggctaacatgagaactcttacacctcgggtt cttcatcccagaaactctgagagccaaactagtcctgcacagcatcacagaagagctcaa acaccagaagacacaaagtctgaatcctctctgagcttcaccttgcacctcagccctgct agaccccagcagaacccggcgccggaaaccaaaagcagaacaattcagagctgggagtcg gctgagaaggaggaaggatttggatacatgatgatgtccccgactgtcagccacagcctg tctgagttacctcaggatgattacgttgtcatggagagtccacaaaaactcaactggcca ggatactgctcctcttcatcgtcctcttcccttcagacgtcgttcagcagctccacctgt gacagcttctctcctctgcatccttcacgccttcagagcagtgacatcagtcggcaatgc tgcccggggactccagaaaacgtcccgtcgtcaatggaaaccagcttttctgcccagcca cagcaggctcaggactttgatcggtctttcctgattcctccatttctgttgagtggctca ggaacgaaaaagcctccacagtccagtccaaacgctgatacaagccagttcagtcgccct caacctgaacaggagcaggtcagaagacactggctgacaggatgtcttttttcttgcttt caaactggggagaaatcttga

Poecilia reticulata (guppy): 103476518 Help Entry 103476518         CDS       T05149                                  Definition (RefSeq) insulin receptor substrate 2-like isoform X1   KO K07187   insulin receptor substrate 2 Organism pret  Poecilia reticulata (guppy) Pathway pret04068   FoxO signaling pathway pret04140   Autophagy - animal pret04910   Insulin signaling pathway pret04920   Adipocytokine signaling pathway Brite KEGG Orthology (KO) [BR:pret00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103476518  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103476518  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103476518    04920 Adipocytokine signaling pathway     103476518 Domain-containing proteins not elsewhere classified [BR:pret04990]  Phosphotyrosine binding (PTB) domain-containing proteins   IRS related family proteins    103476518 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 Mcp5_PH PH_8 Motif Other DBs NCBI-GeneID:  103476518 NCBI-ProteinID:  XP_008427154 LinkDB All DBs Position LG2 AA seq 1061 aa AA seqDB search MASPPATGGHLLSNGTNDVKKCGYLRKQKHGHRRFFVLRESMERCPARLEYYESEKKWRN KSAAKRVITLDSCLCVNKRADAKHKHLIALYTKDEYFAVAAENEQEQESWYTVLSDLIAE SKVFDSPASTSSLVGFEETTYGQLTPATATYKEVWQVNLKSRGLGQIKNLTGVYRLCLSN RNISFVKLNSETPAVNLQLMNIRRCGHSDSFFFIEVGRSAVTGPGEFWMQAEDSVVAQNI HETILEAMKAMKELSEFRPRSKSQSASTNPISVPTRRNLNNLPPSQTGLVRRSRTDSMAA TSPGRKFTSCRIRTASEGDGSVTRPVSMSIPVGESPTSPNSGYHLMRSHTLSNGRTCRIL ESASNLHHSRSMPMSNSPPAASSPISSSPRGGTRVSTPDKARRPFSCSASISGSLSDTGF LLCDDFSSSPGEHKFLTLTRSDTPDSLSSTPPSRDLSDPCGYMLMEGANGSRSSCGIESQ NCDKAYRKRTHSLTTPRQQKVVTPLSSASLDEYTLMRMAHGQNSHSASPKVCYPEDYGDI EIGSSRSSSSNLGDDGYMPMTPGVAPQSGKTDNYVPMSPMCVSAPKQIVNPRVHPQAATN GYKANSPCSSSLEDSGYMRMWCGSKSSMDSPDRHGEYMNMSPGNPPPLQTPPDYYLSPLA GEPASIKPAYQMGSLTLPAKLQSSKNEDSGQYVLMSPQSSRQKTGESDYYSVMQPCAVQT SPLSPSVPSPVRHHRAENLSYRGRMGRPNRLSLDTLRTLPSMNEHPLPLEPRSPGEYINI DFSSNRSSPPSTVSTESQSSSLGSSGGGQGRSSLSDYMNLELGSHSPKGADTPAERLDTL PELSSCPCSEDDVVYHVECEKSSRSFVDEVKNDYTEMTFAMTSSPPQLVPQNSSSQSCRE KRLSLDDQGVPERIGVFLLGAATSSTVDPDRSAKVIRANPQGRRRHSSETFSSTATVTPV FPSFARGDAVKRPSSVENISSRSSEGSDEEYGSPVTRHSSTGYSNGLNYIALNLLENRDV EKCGNLVGFKPTSSCKGGINGLHNTPYVCLGFKETATTAKD NT seq 3186 nt NT seq  +upstreamnt  +downstreamnt atggcaagtcctccggcgacgggaggacacctgttatctaatgggacgaatgacgtgaag aagtgcggctacctgaggaagcagaaacacggacacaggcgtttttttgtgctccgggag tccatggagcgctgtcccgcaaggctggagtattatgaaagcgagaagaaatggagaaat aagtccgcagccaaacgcgtcataactttggactcctgtctgtgcgtaaacaaacgcgcc gatgccaaacacaagcacctcatcgccctctacaccaaggacgaatactttgctgtggct gcagaaaacgagcaggagcaggagagctggtacaccgttctgtctgatttaatagcagag agcaaagtgtttgacagccctgcttccacatcctctttagtggggtttgaggagaccact tacggacagcttacccctgcaacagctacctacaaggaggtgtggcaggtcaacttgaaa tccagaggcttgggtcagatcaaaaacctcactggagtctacaggctgtgtttatccaac cgaaacatcagcttcgtcaagctgaactctgagacaccagctgtcaacctccaactcatg aacatcagaagatgtggccactccgacagcttcttcttcatagaggtgggcagatcagca gtaaccgggccaggggagttctggatgcaagcagaggattcagtggtagcgcagaatatc catgagaccatcctggaggcaatgaaggcgatgaaggagctctctgaattcaggccgagg agcaaaagccagtcagccagcaccaaccccatctctgtgcccacccgacgcaacctcaac aacctccccccaagtcagaccggcctggtgaggagatccagaaccgacagcatggctgcc acatccccagggaggaagttcacctcctgtcggataaggacggccagtgagggagatgga agcgtaacccggccagtgtccatgtccataccagtgggtgagagtcccaccagtcccaat tctggatatcatctcatgaggtcccacacccttagcaatgggcgcacctgcaggatactg gagtctgcatccaatctccatcacagtcgttcaatgccaatgtccaactctcctcctgcc gcctccagcccaatcagctcatctcccaggggaggaacaagggtctccactccagacaaa gccagacgtcctttcagctgcagcgcctccatatctggctccctcagcgatactggcttc cttctctgtgatgatttcagctccagcccaggtgaacacaaatttctcactctgactcgc agtgacactcctgactccctgtccagcacacctccatcccgtgacctgagcgacccctgc ggctacatgctaatggagggggctaacggcagcaggtccagctgtgggatcgagagtcag aattgtgacaaggcatacaggaagcgaacacactccctcaccacaccacgccaacagaag gtggtgactccattgtcctctgcttccttggatgagtacactctaatgaggatggcccat gggcaaaactctcactctgcttcacccaaagtatgctatcctgaggattatggggacatt gaaattggttcatccaggagctccagtagcaaccttggcgatgatggttacatgcccatg acgccaggtgtagcacctcagtctggcaagacggataactatgtacccatgagccccatg tgtgtctcagcaccaaagcagattgtcaaccccagggtgcatccccaggcagctaccaat ggctacaaggccaactctccctgtagcagctctctggaagacagcggatacatgagaatg tggtgcggctccaaatcctccatggacagccctgacagacacggtgaatacatgaacatg tcacctggaaacccaccccctctgcagacccctcctgattactacttaagccctctcgct ggggaaccagcgtcaattaagccggcttaccagatgggctccctcacactgcctgcaaaa cttcagtcatccaagaatgaagacagtggccagtatgtgttaatgagcccacagagttca aggcagaagactggggagtcagactattattcagtaatgcaaccgtgtgcagttcaaaca tcaccgctgagcccctcagtcccctccccagtcaggcatcatcgagcagagaatctgtcc tacagagggaggatggggagacctaacaggctgtctctggacaccctgaggacccttccc agcatgaatgagcatcccctgcccttagagccccgcagccccggcgagtacatcaacatc gacttcagcagcaacagatcgtccccaccgtccaccgtatccacagagagccagtcttca tctttggggtccagcggcgggggccaggggcggtcatctctgtcagactacatgaacctg gagctgggctcacactcgcccaagggggctgacactccagctgagcgactggataccctg cctgagctgtcctcatgcccctgctcagaggacgatgttgtgtaccatgtagagtgtgag aaaagctcccgaagctttgtcgatgaggtgaaaaatgactatactgagatgacattcgca atgactagctcacccccacagcttgttcctcagaactcaagcagccagagctgcagggag aagaggctatctcttgatgaccaaggtgttcctgaacggattggggtcttcctgcttgga gcagcaacttcctcaaccgtggacccagaccgctctgccaaggtcatccgggccaatcca caagggcgaaggcgccacagttcagaaaccttctcctccacggccacagtgacgccggtc tttccctcatttgcacgcggcgacgctgtgaaaaggccgagctcggtggagaacatctcg tcccgcagcagtgagggttccgacgaggagtatggcagtcccgtgacccgccacagctcg accggctactctaacggactgaactacatcgccttgaacctactagaaaacagggatgtg gagaaatgtggaaacctggttggctttaaacccaccagcagctgcaaagggggcatcaat ggattacacaacacaccttacgtctgtttggggttcaaggagactgcaaccactgccaaa gactga

Poecilia reticulata (guppy): 103480255 Help Entry 103480255         CDS       T05149                                  Definition (RefSeq) insulin receptor substrate 2-B-like   KO K07187   insulin receptor substrate 2 Organism pret  Poecilia reticulata (guppy) Pathway pret04068   FoxO signaling pathway pret04140   Autophagy - animal pret04910   Insulin signaling pathway pret04920   Adipocytokine signaling pathway Brite KEGG Orthology (KO) [BR:pret00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103480255  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103480255  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103480255    04920 Adipocytokine signaling pathway     103480255 Domain-containing proteins not elsewhere classified [BR:pret04990]  Phosphotyrosine binding (PTB) domain-containing proteins   IRS related family proteins    103480255 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH_11 PH PH_8 Motif Other DBs NCBI-GeneID:  103480255 NCBI-ProteinID:  XP_008433362 UniProt:  A0A3P9NHH1 LinkDB All DBs Position LG18 AA seq 1360 aa AA seqDB search MANFTNYQEGKAAMLMVEPQQRDVGTSPAAAKANGDSSVGEPPSPLINIGGGGGGSRFHQ HLPPPNHLHHHQNLSLDSPKDQQQHHHYQLAPQQHLSGENTTESPGRKASSSSSISQVHT AEDPAASGSGSSHVYAAVTVANSSEVVDDIRKCGYLRKQKHGHKRFFVLRAASHLGPSRL EYYDSEKKFRNSLRTAAAASGGAVAASPPKRVIYLYQCFTVNKRADSKNKHLIALYTKDE YFAIVAENETEQEDWYVAISELMSEGKRGHVDSDDLDDGYGTVSPGTVFKEVWQVNVKPK GLGQTKNLTGVYRLCLSTKTIHLVKLNSETPCVNLQLMNIRRCGHSESFFFIEVGRSSSI GPGEIWMQVDDSVVAQNMHETILETMKALKAFAEFRPRSKSQSSGSNPMSFITTRRHLGN LPPSQTGLQRRSRTESVVGTPPSSKSSGASGYRFRTSSEGEGTMNRPFRSATGSLVHLNA ARVPHGRQDSGGSGSSWSGVATGNAGTSTTSNRYVRAIPSTCHARSASLPVSHFPSTTSP VSVSSSSGHGSVSDTLTRPSSASICGSPSDGGFNSSDEYGSSPGDFRYFRVRSNTPDSLG NTPPIREENCLNDYMAMGWNRDVFGTSVGSGNNSGCETPRDESTSTTEDERFSSSSLRRR THSFSRAAAGVTGASGVATYQKMTQTNLSLDEGSDVVLPFGSGLLRGGPSSSSSSLRSDY SSCSEHSQQSRPSTLSRSEAGAERPPLSSSSSAKEDSGYMPMMCGVAMASPRDTPPDYMP MQPSSYSYQISHSPQFHSPALGTRSAHHHPQSSTDSHGYMMMLPGSSGTSPSPLQASSSG PGAAGVGGSNSMAEKPENGEYMDMSYSGCGRKLPGEDSSVYYTPGTPEGPLKSYSPYFSL PRSYKAPNREREEREDGEYVPMSSPAKPVYSSVATASMLVPEKRIGGGSNTSTPSHPPPP YGAHHTTAAMADRRVMRPTRLPLGRRSFNGPLRVGEPATETPCATRSVPVTSVPREGPSS PGEYINIEFGEHFPHQQQPPPYPLSTQDEAPSLVSSDACCSPPQDYMSVEVGSDQHDATA CLGKNQSPRPSLVAPWNPPSYIRPLVNSSGVAGSGGHWRSVGDDYTDMSFNLSRGERTQS PTAMLQHLCVVEGRYGHPASTTSSSTISPPHPPSTQQSEPKVVRADPQGRRRHSSETFSS SSSSNSTPSSSATHPSLSNPSAPNANGSYQTEGQTSRWASSASFDSVWMSLAGAGDSPVH HSQVRNAETDAMSGNIPTSASSGVGASRMCRNTSVGYQNGLNYIALELREDGSNAGAPGA SSSSGNASVAPPGMVPLPENGAYASIDFTKSDGVTTATKD NT seq 4083 nt NT seq  +upstreamnt  +downstreamnt atggctaacttcacgaattaccaggagggtaaggcggctatgttgatggtggagcctcag cagagggacgtggggacgagtcctgcggccgccaaagcaaacggagacagctcagtcggg gaacccccttccccgttaattaatatcggcggcggcggaggaggctctcgttttcaccaa catttgccgccccccaatcaccttcaccaccaccaaaacctcagcctcgactcgccaaag gatcaacagcagcaccatcactaccagctggccccacagcagcatctttccggggaaaac accaccgagtccccgggcagaaaagcctcctcctcctcttctatcagccaggtacacaca gccgaggaccccgccgctagcggcagcggcagcagccatgtatacgccgctgtgaccgtc gctaacagctcggaagtcgtggatgatattcgaaagtgcggttatttgagaaagcagaaa cacggacacaagcggtttttcgtgctccgggctgccagccatctggggccgagtcgtctg gaatactacgacagcgagaagaaattcagaaacagcctgcgcaccgctgccgccgctagc ggaggagcggtggccgcttcgcctccgaagagggttatttacctctaccagtgtttcaca gtgaacaaaagggcggactctaaaaacaaacacctcattgccctgtacaccaaggacgaa tattttgctattgtggctgaaaacgagacggagcaggaggactggtatgtggccatcagt gagttaatgagtgaggggaagagggggcacgtggactctgatgatttagatgatggctat ggtacagtcagccctgggactgtgtttaaggaggtttggcaggttaatgttaaacctaaa ggactgggtcaaactaaaaacctcacaggtgtttatcggctatgcctgtctactaaaacc attcacctcgttaaactgaactctgaaaccccctgcgttaacctccagctgatgaacatc aggcgctgtggacactctgagagcttcttcttcatagaggtgggccgctcctcctccatc gggcctggggaaatatggatgcaggtggacgactcggtggtggcccagaacatgcacgag accatcctggaaacaatgaaagccctgaaagcttttgcagaattccggccgaggagcaaa agccaatcttcaggctccaaccccatgtcgttcatcaccacgcgacgccacctgggtaac ctgcctccaagtcagacggggttgcagcggcggtcgaggacggagtctgtagtcggcacg ccaccctctagtaaaagttccggggcgagcggctatcgcttccgcacatctagcgaaggt gaggggacgatgaatcggccatttcgctctgccacgggaagcctggtccacctcaacgca gcccgtgttccccatggccgtcaggacagcggcgggagtggcagcagctggagtggtgtt gcaacaggaaatgctggcacgagcactaccagcaaccgctatgtcagagctatcccctcc acctgtcacgcccgctcagcctcacttcccgtctcccacttcccttcgaccaccagccca gtcagtgtttcctccagcagcggccatggctctgtttctgacacgctcacccgcccatca agcgcctctatatgtggctccccatccgatggaggctttaactcctctgatgagtacggc tccagtcccggtgacttccggtacttccgggtgaggagcaacacgccggattctctgggc aacaccccaccaatcagagaggaaaactgcctcaacgattacatggccatgggctggaac cgggacgttttcggcaccagtgtgggctctggaaacaacagtggatgtgagacaccacgt gatgagagtacctcaacgaccgaggatgagcgcttttcttcctcatcactgaggaggagg acgcactccttctccagagcagctgccggtgtgaccggagcctccggagtagctacttat cagaaaatgacccagacgaacctctcgctggatgaggggtcagacgtagtgctgccattt gggagcgggctgctccgtggtgggccgtcctcttcctcttcctcacttcgctccgactac agctcatgctccgaacatagtcagcagagccgtccctcgacactctccaggtcggaggcc ggagccgaacgcccccctctttcttcctcctcttctgccaaggaagacagcggctacatg cccatgatgtgtggtgtggcaatggcgtcgccgcgggacactcctcctgactacatgcct atgcaaccctcttcttactcctaccagatctcccactcaccccagttccacagcccagct ctagggacgcgctcagcccaccatcacccacaatcttccacggactctcacggctacatg atgatgctcccagggagcagtggcacctctccttctcctctccaggcctcttccagtggt cctggagctgctggtgttggtggaagtaacagcatggctgagaaacctgaaaacggagaa tatatggacatgtcctacagcggctgtggtcgcaagctcccaggtgaagacagcagtgtg tattacacaccaggaacacccgaggggcccctgaagtcttacagtccttacttctctctc ccccgctcttataaggcccccaacagggagagggaagagagagaggatggggaatacgta cccatgagttcccctgccaaaccagtgtattcgtcagttgcaactgcttcaatgttggtg ccagaaaaaagaataggagggggcagcaacacctccactccctcccacccacctcctccc tatggagctcaccatacaactgcggcaatggctgaccgacgggtcatgagacctacccgc cttcctttaggcaggaggagtttcaatggcccgctgcgggtcggcgagcccgccacagag accccgtgtgctacaaggtctgtcccagtcaccagcgtcccacgcgaaggcccctcaagt cccggagagtatatcaatattgagtttggagaacacttccctcaccaacagcagccccct ccctatcccttgtccactcaagatgaagccccctccctggtatccagtgacgcttgctgc tctcctccccaagactacatgagcgtggaggtcgggtcggaccagcatgatgccactgcg tgtctgggtaagaaccagtcccccaggcccagccttgttgctccttggaacccgcccagc tacatccgacctctggttaacagctctggggtcgccggttcaggcggtcactggaggtcg gtaggagacgattacacggacatgtcattcaacctcagcagaggtgagaggactcaaagc cccacagcgatgctgcagcatctttgcgtcgtagagggacgctatggtcaccctgcctcc accacctcctcgtctaccatttccccacctcaccctccttcgacccaacagtcggagccc aaggtggtgcgagcggacccccaaggcaggaggagacacagctcagaaacgttctcctcc agctcatcctctaactcaacgccttcgtcctcagccacccatccgtctctgtccaacccc tcggccccgaatgccaatggatcctaccagacggagggacagacctccaggtgggccagc tcggcgtctttcgacagcgtgtggatgtccttggcgggcgcaggagactcgccagttcac cactcccaggtgagaaatgcagaaactgacgccatgtccgggaacatcccaacgtccgcc tcctcgggggttggcgccagcagaatgtgcaggaacacgtccgtcggctaccagaacggc ctcaactacatcgccttggagctgagggaagatgggagcaacgcaggagcgccaggggcc agtagcagcagcgggaatgcatcagtggcgccgccagggatggtacctctgccagagaat ggagcctacgccagcatagacttcaccaaatcggatggagtcaccacagcaaccaaggac tga

Poecilia reticulata (guppy): 103480483 Help Entry 103480483         CDS       T05149                                  Definition (RefSeq) insulin receptor substrate 1-B-like   KO K16172   insulin receptor substrate 1 Organism pret  Poecilia reticulata (guppy) Pathway pret04068   FoxO signaling pathway pret04140   Autophagy - animal pret04150   mTOR signaling pathway pret04910   Insulin signaling pathway pret04920   Adipocytokine signaling pathway Brite KEGG Orthology (KO) [BR:pret00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103480483    04150 mTOR signaling pathway     103480483  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103480483  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103480483    04920 Adipocytokine signaling pathway     103480483 Domain-containing proteins not elsewhere classified [BR:pret04990]  Phosphotyrosine binding (PTB) domain-containing proteins   IRS related family proteins    103480483 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 PH_8 Motif Other DBs NCBI-GeneID:  103480483 NCBI-ProteinID:  XP_008433662 UniProt:  A0A3P9P8R6 LinkDB All DBs Position LG18 AA seq 1274 aa AA seqDB search MEGQAGELHGNEDVRKSGYLRKQKSMHRRYFVLRAASERGPARLEYYESEKKFRGKAPVP KKAVALETCFNINKRADSKNKHMIVLYTRAESFAVAAESEEDQDEWFQAMVELQCKSKNP NDSASSGDYGAPNPGPAFKEVWQVKVWPKGLGQAKNLVGIYRLCLTDKTVNFVKLNSDAA AVVLQLMNVRRCGHSENFFFVEVGRSAVTGPGEFWMQVDDSVVAQNMHETLLEAMKALSE EFRQRTKSQSNSGPGGGATASNPISVPSRRHHPNPPPSQVGFLRRPRTEPTLGANVGAPL GSSSASPTPRHSFPRSRTASDGGKSEDGIAGSNPLHSVNTSPSTNGSCSTTPILRSKSAR SVPTTAAKTPFGLMRSISTPAPSPAPSLSSSSGHGSEFGGITSAGAVPGSGAYTRVASHH TSVSCSPSDYGSSDEYGSSPGDHAVLPSPSLPGSSVSSTGSQCLGEDGANYILMGQRGGS SGGVSNSNQGNMISSSQPVPGTPTNGSLPQTRRVLRRSSSRECEAERRLLSKRASLPPMA LERLAPHQRRAEEPTDEDSADYAIMSRSTSRESFASTCSSIQRESTIGSCVGGGGYLDVA GELKTDGGPGIVAGVDNGYMSMLPGVTQPPVSSCQTMTVSVPESDSKPADDYMAMTPNNS VSPPQQIRPLPVSDGYMIMSPNSSCSPDQRGSLSEGAWVGSADSRAGSDYMNMSPISAPS VNGSPPQNEHTCHLETSLQQPPPKMVYSYYSLPRSYKHNPTSGLFDDGPGRGRRPNGNCS RGRGGGKNSGGHLEQPAGSSGTGRHQSLSSSSYSSSSASSESLGDNDDRTNQALGNVTTG SQPKEVSKIAQRRSSGGLTKQGSHFRSRPVSLFVDVSKANTLPRVRENPLPPEPKSPGEY VSIEFKGEQCSRSGVGVGRGRGLRHGSLLNHGSSHQHSQNRPTPSLETFIPLSHSPSAPV SPPTPSEYVNMDLGPSPSPSPHSNTQLVFPPFHTPPTPPVLAHAPKTCTEGTASLCQGTV EVAEPPLRKSRDSVPSVTETESPTSCGDYTEMAFSLNNNTAPRSSPRVSPKVPSPTRTDP SVSVLSRGLDFPLGKSGLNPDQGAKVIRADPQGRRRHCSETFVATPSLSTSASTSSSTAS LFPEHTQAVARRLGFESMLWGNGAVTDPPTQFPLPAQQSLPANNQTLSTEQGLNYIDLDL VNKESPHTGLEGATGGQPQSRLFSVLGSGSVVGGMGATAGGSSSSSLNTYASIDFYKSEE LRTHQNGNKEGTEC NT seq 3825 nt NT seq  +upstreamnt  +downstreamnt atggagggccaagcgggcgagctgcacggcaacgaggacgtgcgcaagagcggctacctc cgcaagcagaagtccatgcaccggcgctacttcgtgctgcgcgccgcctcggagcgcggt ccggcccgcctggagtactacgagagcgagaagaagttccgcggcaaggcccccgtgccg aagaaggcggtggcgctggagacgtgcttcaacatcaacaagcgggccgactccaagaac aagcacatgatcgtgctgtacacccgggcggagagcttcgccgtggccgcggagagcgag gaggaccaggacgagtggttccaggccatggtggagctgcagtgcaaaagtaaaaatcct aacgacagtgcgagttcaggggactatggcgcgccaaatccaggacctgcgttcaaagaa gtttggcaggtgaaggtgtggcctaaaggcctgggtcaggccaagaacctggtgggcatc tatcgcctctgccttaccgacaagacggtaaactttgtgaagctgaactccgacgcagcc gctgtggtgctgcagctgatgaacgtcaggcgttgcggacattcggaaaactttttcttt gtcgaggtgggacgctctgctgtgacgggccccggcgagttttggatgcaggtcgatgat tctgtggtggcccagaacatgcatgaaaccttgctggaggccatgaaagccctgagtgag gagtttcgccagcgcacaaagtctcagtcaaactctggtcctggaggaggcgccacagct tccaatcctatcagtgttccttctcggcgccaccatcccaatccccctccaagccaggtg ggcttcctccgccgtccccgaactgagcctaccttaggtgctaatgtgggagctccgtta ggcagttccagtgcctctcccacgcctcggcacagcttcccgaggtcccgcactgccagc gatggagggaaaagtgaagatgggatagcaggatccaatccgctccacagtgtaaacaca agtccttctaccaatggctcctgctctaccaccccgatcctcaggtcaaagtcagcccgc tcagtcccaaccacagctgctaaaactccttttgggttgatgcgttccatttcaactccg gccccatcaccggccccaagtctgtcgtccagctctgggcacggatctgagtttggaggc atcacatctgctggtgctgtcccagggtctggtgcttatactcgtgtagcctctcatcat acctcagtctcgtgctcacccagtgattacggctcctcagatgagtatggttccagtcct ggagatcacgcggttctaccctctccgagcctgccaggaagctctgtcagcagcactggc agccagtgccttggcgaggatggagcgaactacatcctaatgggtcaacgaggtgggagc agtggtggtgtcagcaacagtaatcaaggcaacatgatatccagctcccaacctgtacca ggaacaccaactaatggctcactgccccagaccaggagagtattgcgtcgatcttctagc cgtgaatgtgaggctgaacgcaggcttctgagcaagcgtgcatccttgcctcctatggcc ctggaaagactggccccacaccagcgcagagctgaggaacctacggatgaagattcagct gattatgccattatgtcaaggagcaccagtcgggagtcctttgcatctacctgctcatct attcaaagggaatcaaccataggctcttgtgtagggggaggagggtacttggatgtagca ggagagttaaaaactgatggtggtccaggaatagttgcaggtgtggacaatgggtacatg tccatgctaccaggagtcacccagccgcctgtttcctcatgtcagacaatgactgtctct gttccagaatcagattccaaacctgctgatgactacatggccatgacccccaacaatagc gtgtctcccccgcagcagattcgtcccctgccagtgtctgacggctatatgataatgtca cccaacagcagttgctcccctgaccagcgtggaagcctctctgaaggcgcttgggttggc agtgccgatagcagagctggtagcgactacatgaacatgtctcccattagtgcaccttct gtaaatggcagtccacctcaaaatgagcacacctgccatttggaaaccagtttgcaacag ccgcccccaaagatggtgtattcctattattcccttcccagatcgtacaaacataatccc acttctgggctttttgacgacgggcccggacgaggtagacgccccaatgggaactgtagc agagggagaggtggcggcaaaaactcaggggggcatctagagcagccagcaggcagttca gggactggacggcaccagtcactctcttcgtcctcatactcctccagctcagctagcagt gagagtcttggagataacgatgacaggactaaccaggctctgggtaatgtgacaactggt tctcagcccaaagaggtgagcaagattgctcagaggcggagctctggtgggttaacaaag caaggtagccactttagaagcagaccagtaagcctatttgtagatgtatctaaggccaac actcttcctagggtccgtgagaaccccttacccccagaacctaagagccctggagagtat gtgagcattgaatttaaaggggagcagtgcagccggtctggtgtaggagttgggcgaggt agaggcctgagacatggatcattgctgaatcatggctcaagtcaccagcattctcaaaac agaccaactccatctctagaaaccttcattcccctgtctcatagtccctctgcccctgtc tctccaccaactccatcagagtacgtcaacatggacctcggtccttcaccatccccttca ccccattccaatacccagttagtttttccacctttccacacccctcccacacccccagtt cttgctcatgcccctaaaacctgtacggaaggtactgctagtctgtgccaagggactgtt gaagttgctgagccacctcttaggaaaagcagagacagtgttccctcagtgactgagaca gagtctcctacatcctgtggagactacacagagatggctttcagcttgaacaacaacact gcccctcggtcatcgccaagggtctccccaaaagtcccctctcctacaagaactgatcct tctgtttcagtgctctctcggggtctagacttccctctaggcaaatcaggactgaaccca gaccagggtgctaaagtaatccgtgctgatccccaaggacgcaggcgccactgctcagaa acctttgtggccacaccctccctgtccacctctgcttctacttcttcttctactgcctcc ctctttccagagcacacccaggccgtcgcccgccgcctcggctttgagagcatgttgtgg gggaacggtgccgtcactgatcctccaactcaatttccactccctgcacagcagtcactt cccgcaaacaatcagacattatccacggagcagggtctcaactacatagacttggacttg gtcaacaaagagagtccccacactggcctggaaggcgccacaggaggccagccccaatct cggctgttctctgttcttgggtcgggctccgtggttgggggaatgggggcaacagctgga gggagcagcagttcaagcctcaacacatacgccagcatcgacttctacaaatccgaggag ctacggacacatcagaacgggaacaaagagggaacagagtgctga

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