Panthera tigris altaica (Amur tiger): 102957386 Help Entry 102957386         CDS       T02988                                  Gene name CYP3A131 Definition (RefSeq) cytochrome P450 3A12   KO K07424   cytochrome P450 family 3 subfamily A [EC:1.14.14.1] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg00140   Steroid hormone biosynthesis ptg00591   Linoleic acid metabolism ptg00830   Retinol metabolism ptg01100   Metabolic pathways ptg05204   Chemical carcinogenesis Brite KEGG Orthology (KO) [BR:ptg00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     102957386 (CYP3A131)    00591 Linoleic acid metabolism     102957386 (CYP3A131)   09108 Metabolism of cofactors and vitamins    00830 Retinol metabolism     102957386 (CYP3A131)  09160 Human Diseases   09161 Cancer: overview    05204 Chemical carcinogenesis     102957386 (CYP3A131)  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:ptg00199]     102957386 (CYP3A131) Enzymes [BR:ptg01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.1  unspecific monooxygenase      102957386 (CYP3A131) Cytochrome P450 [BR:ptg00199]  Cytochrome P450, animal type   CYP3 family    102957386 (CYP3A131) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 Motif Other DBs NCBI-GeneID:  102957386 NCBI-ProteinID:  XP_007081124 LinkDB All DBs Position Un AA seq 503 aa AA seqDB search MDLIPSFSTETWLLLATSLVLLYLYGTHTHGLFKKLGIPGPKPLPFFGTALGYRQGFCEF DEKCFRTYGRMWGFYDGRQPVLAITDPDMIKTVLVKECYSVFTNRRSLGPVGFMKSAISL SEDEQWKRIRTLLSPTFTSGKLKEMFPIVGQYGDVLVRNLRKEAEKGNPVTLKDILGAYS MDVITSTSFGVNIDSLNNPRDPFVENTKKLLKFSFLDPFFFSLLLFPFLNPVFELLNIWL FPKSVINFFTKSVKRMKESRLKDKQKHRVDLLQLMINSQNSKETDTHKALSDLELVAQSV IFIFAGYEPTSTSLSFLVYELATHPDVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVL NETLRLYPIAGRLERVCKRDVEISGVFIPKGTVVMVPTFTLHRDLDLWPEPEEFHPERFS KKNKDSINPYIYLPFGTGPRNCIGMRFATMNMKLALVTLLQNFSFKPCEETQIPLKLNAQ GIIQPEKPIVLKVELRDGSVSRA NT seq 1512 nt NT seq  +upstreamnt  +downstreamnt atggacctgatcccaagcttttccacagaaacctggcttctcctggctaccagcctggtg cttctctatctatatgggacccacacacatggactttttaagaagctgggaattcctggg ccaaaacctctgcctttttttggaactgctctggggtaccgtcagggtttttgtgaattt gatgagaaatgttttagaacgtatggaagaatgtgggggttttatgatgggcggcagcca gtgttggcgatcacagatccagacatgatcaaaacagtactagtgaaagaatgctattct gtcttcacaaaccggcggagtcttggtccagtgggatttatgaaaagtgccatctctctg tctgaagatgaacaatggaagagaatacgaacattgctgtctccaaccttcaccagtgga aaactcaaggagatgttccccatcgttggccagtatggagatgtgttggtgaggaacctg aggaaggaggcagagaaaggcaatcctgtcaccttgaaagacatcttgggggcctacagc atggatgtgattactagcacatcgtttggagtgaacattgattccctcaacaacccacga gatccctttgtggaaaataccaagaagctcttaaaattttcgtttctggatccatttttc ttctcattattactcttcccattccttaacccagtttttgaactattaaatatctggctg tttccaaaaagtgtcattaattttttcacaaaatctgtaaaaaggatgaaggaaagtcgc ctcaaagataaacaaaagcaccgagtggatttgcttcagctgatgattaactcccagaat tccaaagaaacggacacccataaagctctgtctgatctggagctcgtggcccaatctgtt atctttatttttgctggctatgagcccaccagcacttctctttccttccttgtgtatgaa ttggccactcatcctgatgtccagcagaaactgcaggaggagattgatgcaactttccct aacaaggcacctcccacttatgatgctcttgtacagatggagtatcttgacatggtgttg aatgaaaccctcagattatacccaatcgctggtagacttgagagggtctgtaagagagat gtggaaatcagtggtgtgttcattcccaaagggacagtggtgatggtgccaacctttact cttcaccgggacctggatctctggccagagcctgaggagttccatcctgaaaggttcagc aagaagaacaaggacagcataaatccttatatatacctgccttttggaactggaccccga aactgcattggcatgaggtttgcgaccatgaacatgaaacttgcccttgtcacactcctt cagaacttctccttcaaaccttgtgaagaaacacagatccccctgaaattaaatgctcaa ggtattattcaaccagaaaaacccattgttctcaaggttgagctgagagatgggagtgtg agtagagcctga

Panthera tigris altaica (Amur tiger): 102957670 Help Entry 102957670         CDS       T02988                                  Definition (RefSeq) cytochrome P450 3A12-like   KO K07424   cytochrome P450 family 3 subfamily A [EC:1.14.14.1] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg00140   Steroid hormone biosynthesis ptg00591   Linoleic acid metabolism ptg00830   Retinol metabolism ptg01100   Metabolic pathways ptg05204   Chemical carcinogenesis Brite KEGG Orthology (KO) [BR:ptg00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     102957670    00591 Linoleic acid metabolism     102957670   09108 Metabolism of cofactors and vitamins    00830 Retinol metabolism     102957670  09160 Human Diseases   09161 Cancer: overview    05204 Chemical carcinogenesis     102957670  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:ptg00199]     102957670 Enzymes [BR:ptg01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.1  unspecific monooxygenase      102957670 Cytochrome P450 [BR:ptg00199]  Cytochrome P450, animal type   CYP3 family    102957670 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 Motif Other DBs NCBI-GeneID:  102957670 NCBI-ProteinID:  XP_007081125 LinkDB All DBs Position Un AA seq 503 aa AA seqDB search MDLLPSFSIETWLLLATSLVLLYLYGTYTHGLFKKLGIPGPKPLPFVGTALGYRQSFCEF DKKCFKTYGRMWGFYDGRQPVLAITDPDMIKTVLVKECYSVFTNRRSLGPVGFMKSAISL SEDEQWKRIRTVLSPTFTSGKLKEMFPIIGQYGDVLVRNLRKEAEKGNPVTLKDIFGAYS MDVITGTSFGVNIDSLNNPQDPFVENTKNLLKFSFLDPLFFSNILFPFLTPVFELLNIWL FPKKVTDFFTKSVKRMKESRLKDKQKHQVDLLQLMINSQNSKETDTHKALSDLELVAQSI MFIFAGYETTSTSLSFLVYELATHPDVQQKLQEEIDATFPDKAPPTYDALVQMEYLDMVL NEALRLYPIVGRLERVCKRDVEISGVFIPKGAVVMVPTFTLHRDLDLWPEPEEFCPERFN KKNKDSINPYIYLPFGTGPRNCIGKRFAIMNMKLALVRVLQNFSFKPCKETQIPPKLNAL SIIQPEKPIVLKVELRDGSVNRA NT seq 1512 nt NT seq  +upstreamnt  +downstreamnt atggacctgctcccaagcttttccatagaaacctggcttctcctggctaccagcctggtg cttctctatctatatgggacctacacacatggactttttaagaagctcggaattcctggg ccaaaacctctgccttttgtgggaactgctctggggtaccgtcagagcttttgtgaattt gacaagaaatgttttaaaacatatggaagaatgtgggggttttatgatgggcggcagcca gtgttggcgatcacagatccagacatgatcaaaacagtactagtgaaagaatgctattct gtcttcacaaaccggcggagtcttggtccagtgggatttatgaaaagtgccatttctctg tctgaggatgaacaatggaagagaatacgaacagtgctgtctccaaccttcaccagtggg aagctcaaggagatgttccccatcattggccagtatggagatgtgttggtgaggaacctg aggaaggaggcagagaaaggcaatcctgtcaccttgaaagacatctttggggcctacagc atggatgtgattactggtacctcctttggagtgaacattgattccctcaacaacccacaa gatccctttgtggaaaatacgaagaatctcttaaaattttccttccttgatccacttttc ttctcaaatatactcttcccattccttaccccagtttttgaactattaaatatctggctg tttccaaaaaaagttactgattttttcacaaaatctgtaaaaaggatgaaggaaagtcgc ctcaaagataaacaaaagcaccaagtggatttgctccagctgatgattaactcccagaat tccaaagaaacagacacccataaagctctgtctgatctagagcttgtggcccaatctatt atgtttatttttgctggctatgagaccacaagcacttctctttccttccttgtgtatgaa ttggccactcaccctgatgtccagcagaaactgcaggaggagattgatgcgactttcccc gataaggcacctcccacttatgatgcccttgtacagatggagtatcttgacatggtgttg aatgaagctctcagattatatccaatcgttggtagacttgagagggtctgtaagagagat gtggaaatcagtggtgtgttcattcccaaaggggcagtagtgatggtgccaacctttact cttcaccgggacctggatctctggccagagcctgaggaattctgtcctgaaaggttcaac aagaagaacaaggatagtataaatccttatatatacctgccttttggaactggaccccga aactgcattggcaagaggttcgcgattatgaacatgaaacttgcccttgtcagagtcctg cagaacttctccttcaagccttgtaaagaaacacagatcccaccgaaattaaacgctcta agtattattcaaccagaaaaacccattgttctcaaggttgagctgagagatgggagtgtg aatcgagcttga

Panthera tigris altaica (Amur tiger): 102966263 Help Entry 102966263         CDS       T02988                                  Definition (RefSeq) cytochrome P450 1A1   KO K07408   cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg00140   Steroid hormone biosynthesis ptg00380   Tryptophan metabolism ptg00830   Retinol metabolism ptg00980   Metabolism of xenobiotics by cytochrome P450 ptg01100   Metabolic pathways ptg04913   Ovarian steroidogenesis ptg05204   Chemical carcinogenesis Brite KEGG Orthology (KO) [BR:ptg00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     102966263   09105 Amino acid metabolism    00380 Tryptophan metabolism     102966263   09108 Metabolism of cofactors and vitamins    00830 Retinol metabolism     102966263   09111 Xenobiotics biodegradation and metabolism    00980 Metabolism of xenobiotics by cytochrome P450     102966263  09150 Organismal Systems   09152 Endocrine system    04913 Ovarian steroidogenesis     102966263  09160 Human Diseases   09161 Cancer: overview    05204 Chemical carcinogenesis     102966263  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:ptg00199]     102966263 Enzymes [BR:ptg01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.1  unspecific monooxygenase      102966263 Cytochrome P450 [BR:ptg00199]  Cytochrome P450, animal type   CYP1 family    102966263 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 Motif Other DBs NCBI-GeneID:  102966263 NCBI-ProteinID:  XP_007084655 LinkDB All DBs Position Un AA seq 517 aa AA seqDB search MMLSVFGLSVPISATELLLASFVFCLVFWVVRAWQPRVPKGLKSPPGPWGWPLLGHVLTL GKNPHLVLARLSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVRQGDDFKGRPDLYSFSLI SEGQSMTFSPDSGPVWAARRRLAQNALKSFSIASDPASSSSCYLEDHVSKEAEYLIGKFQ ELMAKVGHFDPYRYVVVSVANVICAMCFGRRYDHDDQELLSLVNLSNEFGDGAASGNPVD FFPILRYLPNPALDFFKDVNEKFSIFMHKMVKEHYKTFEKGHIRDITDSLIEHCQDKRLD ENANIQLSDEKIVNVVSDLFGAGFDTVTTAISWCLMYLVTSPNVQEKIQKELDTVIGRAR QPRLSDRLQLPYMEAFILEIFRHTSFIPFTIPHSTTKDTSLSGFYIPKERCVFVNQWQIN HDQKLWGDPSEFRPERFLTPDGTINKALSEKVILFGLGKRKCIGETIARLEVFLFLAILL QQVEFSVPQGTKVDMTPIYGLTMKHARCEHFQVRMRT NT seq 1554 nt NT seq  +upstreamnt  +downstreamnt atgatgttgtctgtgtttggactctctgtccccatctcggccacagagcttctcctggcc tcctttgtcttctgcctggtgttctgggtggtcagggcctggcagcctcgggttcccaaa ggcctgaagagtccaccagggccctggggctggcctctgctcgggcacgtgctgaccttg gggaagaacccacatctggtgctggcaaggctgagccagcgttacggggacgtgctgcaa atccgcatcggctccacacccgtgctggtgctcagtggcctggacaccatccggcaggcc ctggtgcgtcagggtgatgatttcaaggggcggcccgatctctacagcttcagtctgatc tctgagggccaaagcatgaccttcagcccagactctggaccggtgtgggctgcccgcagg cgcctggcccagaatgccctgaagagtttctccattgcttcagacccggcttcctcatcc tcctgctacctggaagaccatgtgagcaaggaggctgagtacctcattggcaagttccag gagctgatggcaaaggttgggcactttgacccctacagatatgtagtggtgtcagtggcc aatgtcatctgcgccatgtgttttggccggcgctatgaccatgatgaccaagagctgctt agcttagtcaacctgagtaatgagttcggggatggcgctgcctctgggaaccctgtggac ttcttccccatccttcgatacctacctaaccctgccctggatttcttcaaggacgtgaat gagaagttctccatcttcatgcataagatggtcaaggaacactacaaaacttttgagaag ggtcacattcgggatatcacagacagcctgattgagcactgtcaggacaagaggctggac gagaatgccaatatccagctgtctgacgagaagattgttaatgttgtctcggacctcttc ggagctggatttgacacagtcacaactgccatctcctggtgcctcatgtacctggtgacg agccccaatgtacaggaaaagatccagaaggagctggacacagtgattgggagggcgcgg cagccccggctctctgacagactccagctgccctacatggaagcattcatcctggagatc ttccgacatacctccttcatccctttcactatcccccatagtaccacaaaagacacaagt ctgagtggcttttacatccccaaggagcgttgtgtctttgtgaaccagtggcagatcaac catgaccagaagctatggggtgacccatctgagttccgaccagaacgatttctcactcct gatggcaccatcaacaaggcactgagtgagaaggtgattctctttggtttgggcaagagg aagtgcatcggtgagaccattgcccgcttggaggtctttctcttcctggccatcctgctg cagcaggtggaattcagtgtgccacagggcacgaaggtggatatgacccctatttatggg ctgaccatgaagcatgcccggtgtgagcacttccaagtgcggatgcgcacttag

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