Panthera tigris altaica (Amur tiger): 102960317
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Entry
102960317 CDS
T02988
Gene name
MAP3K5
Definition
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg01524
Platinum drug resistance
ptg04010
MAPK signaling pathway
ptg04071
Sphingolipid signaling pathway
ptg04141
Protein processing in endoplasmic reticulum
ptg04210
Apoptosis
ptg04530
Tight junction
ptg04668
TNF signaling pathway
ptg04714
Thermogenesis
ptg04722
Neurotrophin signaling pathway
ptg04932
Non-alcoholic fatty liver disease
ptg05010
Alzheimer disease
ptg05012
Parkinson disease
ptg05014
Amyotrophic lateral sclerosis
ptg05016
Huntington disease
ptg05017
Spinocerebellar ataxia
ptg05022
Pathways of neurodegeneration - multiple diseases
ptg05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102960317 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102960317 (MAP3K5)
04668 TNF signaling pathway
102960317 (MAP3K5)
04071 Sphingolipid signaling pathway
102960317 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
102960317 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
102960317 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
102960317 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
102960317 (MAP3K5)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102960317 (MAP3K5)
05012 Parkinson disease
102960317 (MAP3K5)
05014 Amyotrophic lateral sclerosis
102960317 (MAP3K5)
05016 Huntington disease
102960317 (MAP3K5)
05017 Spinocerebellar ataxia
102960317 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
102960317 (MAP3K5)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
102960317 (MAP3K5)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102960317 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102960317 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102960317 (MAP3K5)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
102960317 (MAP3K5)
Protein kinases [BR:
ptg01001
]
Serine/threonine kinases: STE group
STE11 family
102960317 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF4071
Pkinase
PK_Tyr_Ser-Thr
ASK_PH
FPP
Pkinase_fungal
Kinase-like
Motif
Other DBs
NCBI-GeneID:
102960317
NCBI-ProteinID:
XP_007096464
LinkDB
All DBs
Position
Un
AA seq
1336 aa
AA seq
DB search
MPATSAAPRSGILVHFRPRLRDASRNPPVLRNAGLPALYQTARRASPAGGRRTTVAYVIN
EASQGQLVMAESEALQSLREACETVGATLETVHFGKLDFGETAVLDRFYNADIAVVEMSD
AFRQPSLFYHLGVRESFSMANNIILYCDNNSDSLQSLKEIICQKNTMCTGNYTFVPYMIT
PHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILN
DIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLE
KLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPLVQSEGQVASDMYCLVGRIYK
DMFLDSNFLDTESRDYGASWFKKAFESEPSLQSGINYAVLLLAAGHQFESSFELRKVGVK
LSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETI
LIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSIN
NEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFC
TELHCKKFFEMVNTITEEKGRSTEEGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGR
DLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVP
GGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVL
KISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK
PPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFL
KVSSKKKKTQPKLSALSAGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSF
KTRAKSCGQRDVKGIRTLFXSIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRIL
TEDQDKVVRNLMESLAQGTEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELD
FDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHF
SLASESDTADQEDLDAEDEREEQPSNQTVQRPHAVIEDAVATSGVSTLSSTVSHDSQNAH
RSLNVQLGRMKIETNRLLEELVQKEKELQALLHQAIEEKDHEIKHLKLKSQPIDIPGVPV
CHRDSLGTNAEESELAEWLREKGADEDTISRFLAEDYSLEDVLYYVTRDDLKCLRLRGGI
LCMLWKAITDFRDKQT
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgccggccacttccgcagcgccacggtcaggaatcctcgtccactttaggccccggctg
cgggacgctagtcgaaatcctccagtcttgcgcaacgcgggcctccccgcgctgtaccag
accgcgcgcagagctagcccggcaggcggccgacggaccacggtggcgtatgtgatcaac
gaagcgagccaggggcagctggtgatggccgagagcgaggccctgcagagcctgcgggag
gcgtgcgagacggtgggcgccaccctggagaccgtgcattttggtaaactggactttggg
gaaaccgcggtgctggatcgtttctacaatgcagatatcgctgtggtggagatgagtgac
gccttccgacagccatcgttgttttaccacctcggggtcagagaaagtttcagcatggcc
aacaacatcatcctctactgtgataataattcagactctctgcagtcactgaaggaaatc
atttgccagaagaatactatgtgcactgggaactacacattcgttccttacatgatcact
ccgcataataaagtctactgctgcgatagcagcttcatgaaggggttgacagagctcatg
caaccgaacttcgagctgcttcttggacccatttgcttacctcttgtggaccgtttcatt
caacttctgaaggtggcacaagcaagttccagccagtatttccgggaatctatactcaat
gatatcaggaaagctcgtaatttatacactggtaaagaattggcagctgaattggcaaga
attcggcagcgagtagataatattgaagtcttgacagcagatattgtcataaacctgtta
ctttcctacagagatatccaggactatgattctattgtgaagctggtagagacgttagaa
aagctgccaacctttgatttggcttcccatcaccatgtgaagtttcattatgcatttgca
ctgaataggagaaatctccctggagacagagcaaaagctcttgatattatgattcccctg
gtgcaaagtgaagggcaagttgcttcagatatgtattgcctagtgggccgaatctacaaa
gatatgtttttggactctaatttcctggacactgaaagtagagactatggagcttcttgg
ttcaaaaaggcatttgaatctgagccatcactacagtcaggaattaattatgcggtcctt
ctcctggcagctgggcaccagtttgaatcttcctttgagctccggaaagttggggtgaag
ctaagtagccttcttggtaaaaagggaaacttagaaaaactccagagctactgggaagtt
ggattttttctgggtgccagtgtcctggccaatgaccacatgagagtcatccaagcatct
gaaaagctttttaaactgaagacgccagcatggtacctcaagtctattgtagagacaatt
ttgatatataagcattttgtgaaactgactacagagcagcctgtggccaaacaggagctg
gtggacttctggatggatttcctggtggaggccacaaagacagatgttactgtagttagg
tttccggtgttaatattagaaccaactaaaatctatcagccttcatatttgtctatcaac
aatgaagttgaggagaagacaatatctatttggcatgtgcttcctgatgacaagaaaggt
atacatgagtggaattttagtgcttcttctgtcaggggagtgagtatttctaaatttgaa
gaacgatgctgttttctttatgtgcttcataattctgacgatttccaaatctatttctgt
acagaacttcattgtaaaaagttttttgaaatggtgaacaccattactgaagagaagggg
agaagcacagaggaaggtgattgtgaaggtgactccttggagtatgactacgaatatgat
gagaacggagacagagttgttttaggaaagggcacttacgggattgtctacgcaggccga
gacctgagcaaccaagtcagaattgctataaaggaaatcccagaaagagatagcagatac
tcccagcccctacatgaagaaatagcattgcataagcatctgaagcataaaaatattgtc
cagtatctgggctctttcagtgagaatggtttcatcaaaatcttcatggagcaggtccca
ggaggaagtctttcagctctccttcgttccaaatggggcccattgaaggacaatgagcaa
acaattggcttctatacaaagcaaatacttgaaggattaaaatacctccatgacaatcag
atagtccaccgggatataaagggtgacaatgtgttgattaatacctacagtggcgttctc
aagatctcagacttcgggacatcaaagaggcttgctggcattaacccgtgtactgaaact
tttactggtacccttcagtatatggcaccagaaatcatagacaaaggaccaagaggctac
gggaaagcagcagacatttggtctttgggctgcacgatcatcgaaatggccacagggaaa
ccacctttttatgaactgggagaaccacaagcagctatgttcaaggtgggaatgtttaaa
gtccacccggagatcccagagtccatgtccgcagaggccaaggcgttcatattgaaatgt
tttgaaccggaccccgacaagagagcctgtgctaatgacttgcttattgacgagttctta
aaagtttcaagcaaaaagaagaagacgcaacctaagctttcagccctctcagctggatca
aatgagtatcttagaagcatatccttgcctgtgcccgtcttggtggaggacaccagcagc
agcagcgaatacggctcggtttctccggacacggagttgaaggtggatcccttctctttc
aagacgagagccaaatcctgtggacagcgagacgtaaaaggaatacggacactctttnac
agcattccagacgaaaatttcgaagaccacagcgctccaccttcccctgaagagaaagat
tctggattctttatgctgaggaaggacagtgagagacgggccactcttcacaggatcctg
accgaagaccaagacaaagttgtgaggaacttaatggaatctttggctcaggggactgaa
gaacctaaactaaaatgggaacacatcacaaccctcattgcaagcctcagagaatttgtg
agatccacggaccgaaaaatcatagccaccacactgtctaagctgaagctagaacttgac
tttgacagccatggcatcagtcaagttcaggtggtactcttcggttttcaagatgccgtc
aataaagttcttcggaatcataacatcaagccacactggatgtttgccttagacagtatc
atccgaaaggcagtgcagacggccatcaccattctggtgccagaactgaggccacatttc
agcctcgcatctgagagtgataccgcggatcaagaagacttggatgcggaagatgagcgt
gaggaacagccttcaaaccaaactgtccaaagacctcatgctgtcattgaagatgccgtg
gctacctcaggggtgagcacgctcagttctactgtatcccatgactcccaaaatgctcac
cgatcactcaatgtgcagcttggaaggatgaaaatagaaactaatagattactggaagaa
ttggttcagaaagagaaagaattacaagcactccttcatcaagctattgaagaaaaagac
cacgaaattaaacacctgaagcttaagtcccaaccaatagatattcctggagtgcctgtg
tgtcaccgggattctctgggcacaaatgctgaagagtctgaacttgctgaatggctgaga
gaaaagggagctgatgaagacactataagtcggtttctggctgaggattattcactagag
gatgttctctactatgttacacgtgatgatttaaaatgcctgagactaaggggaggaata
ctctgcatgctgtggaaggccatcactgactttcgagacaaacagacttga
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