Panthera tigris altaica (Amur tiger): 102962460 Help Entry 102962460         CDS       T02988                                  Symbol CASP8 Name (RefSeq) caspase 8   KO K04398   caspase 8 [EC:3.4.22.61] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg01524   Platinum drug resistance ptg04115   p53 signaling pathway ptg04210   Apoptosis ptg04215   Apoptosis - multiple species ptg04217   Necroptosis ptg04620   Toll-like receptor signaling pathway ptg04621   NOD-like receptor signaling pathway ptg04622   RIG-I-like receptor signaling pathway ptg04623   Cytosolic DNA-sensing pathway ptg04625   C-type lectin receptor signaling pathway ptg04657   IL-17 signaling pathway ptg04668   TNF signaling pathway ptg04932   Non-alcoholic fatty liver disease ptg04936   Alcoholic liver disease ptg05010   Alzheimer disease ptg05016   Huntington disease ptg05022   Pathways of neurodegeneration - multiple diseases ptg05132   Salmonella infection ptg05134   Legionellosis ptg05142   Chagas disease ptg05145   Toxoplasmosis ptg05152   Tuberculosis ptg05160   Hepatitis C ptg05161   Hepatitis B ptg05162   Measles ptg05163   Human cytomegalovirus infection ptg05164   Influenza A ptg05165   Human papillomavirus infection ptg05167   Kaposi sarcoma-associated herpesvirus infection ptg05168   Herpes simplex virus 1 infection ptg05169   Epstein-Barr virus infection ptg05170   Human immunodeficiency virus 1 infection ptg05200   Pathways in cancer ptg05203   Viral carcinogenesis ptg05416   Viral myocarditis ptg05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     102962460 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     102962460 (CASP8)    04215 Apoptosis - multiple species     102962460 (CASP8)    04217 Necroptosis     102962460 (CASP8)    04115 p53 signaling pathway     102962460 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102962460 (CASP8)    04621 NOD-like receptor signaling pathway     102962460 (CASP8)    04622 RIG-I-like receptor signaling pathway     102962460 (CASP8)    04623 Cytosolic DNA-sensing pathway     102962460 (CASP8)    04625 C-type lectin receptor signaling pathway     102962460 (CASP8)    04657 IL-17 signaling pathway     102962460 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102962460 (CASP8)    05203 Viral carcinogenesis     102962460 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102962460 (CASP8)    05161 Hepatitis B     102962460 (CASP8)    05160 Hepatitis C     102962460 (CASP8)    05164 Influenza A     102962460 (CASP8)    05162 Measles     102962460 (CASP8)    05168 Herpes simplex virus 1 infection     102962460 (CASP8)    05163 Human cytomegalovirus infection     102962460 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     102962460 (CASP8)    05169 Epstein-Barr virus infection     102962460 (CASP8)    05165 Human papillomavirus infection     102962460 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     102962460 (CASP8)    05134 Legionellosis     102962460 (CASP8)    05152 Tuberculosis     102962460 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102962460 (CASP8)    05142 Chagas disease     102962460 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     102962460 (CASP8)    05016 Huntington disease     102962460 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     102962460 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102962460 (CASP8)    05416 Viral myocarditis     102962460 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102962460 (CASP8)    04932 Non-alcoholic fatty liver disease     102962460 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102962460 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ptg01002]     102962460 (CASP8) Enzymes [BR:ptg01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      102962460 (CASP8) Peptidases and inhibitors [BR:ptg01002]  Cysteine peptidases   Family C14: caspase family    102962460 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  102962460 NCBI-ProteinID:  XP_007090057 LinkDB All DBs Position Un AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEAMEQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRMSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTNFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagctgggcagtgatgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctgttcaactacctgaac accagcaaggaagcaatggagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaatgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgcggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacaaactttgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccccatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactctgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaggctgattttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccctacggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggcgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctactttcacactgaggaaaaaactcttcttccctcttaattga

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