Panthera tigris altaica (Amur tiger): 102962460 Help Entry 102962460         CDS       T02988                                  Gene name CASP8 Definition (RefSeq) caspase 8   KO K04398   caspase 8 [EC:3.4.22.61] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg01524   Platinum drug resistance ptg04115   p53 signaling pathway ptg04210   Apoptosis ptg04215   Apoptosis - multiple species ptg04217   Necroptosis ptg04620   Toll-like receptor signaling pathway ptg04621   NOD-like receptor signaling pathway ptg04622   RIG-I-like receptor signaling pathway ptg04625   C-type lectin receptor signaling pathway ptg04657   IL-17 signaling pathway ptg04668   TNF signaling pathway ptg04932   Non-alcoholic fatty liver disease ptg05010   Alzheimer disease ptg05016   Huntington disease ptg05022   Pathways of neurodegeneration - multiple diseases ptg05132   Salmonella infection ptg05134   Legionellosis ptg05142   Chagas disease ptg05145   Toxoplasmosis ptg05152   Tuberculosis ptg05160   Hepatitis C ptg05161   Hepatitis B ptg05162   Measles ptg05163   Human cytomegalovirus infection ptg05164   Influenza A ptg05165   Human papillomavirus infection ptg05167   Kaposi sarcoma-associated herpesvirus infection ptg05168   Herpes simplex virus 1 infection ptg05169   Epstein-Barr virus infection ptg05170   Human immunodeficiency virus 1 infection ptg05200   Pathways in cancer ptg05203   Viral carcinogenesis ptg05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     102962460 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     102962460 (CASP8)    04215 Apoptosis - multiple species     102962460 (CASP8)    04217 Necroptosis     102962460 (CASP8)    04115 p53 signaling pathway     102962460 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102962460 (CASP8)    04621 NOD-like receptor signaling pathway     102962460 (CASP8)    04622 RIG-I-like receptor signaling pathway     102962460 (CASP8)    04625 C-type lectin receptor signaling pathway     102962460 (CASP8)    04657 IL-17 signaling pathway     102962460 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102962460 (CASP8)    05203 Viral carcinogenesis     102962460 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     102962460 (CASP8)    05016 Huntington disease     102962460 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     102962460 (CASP8)   09166 Cardiovascular disease    05416 Viral myocarditis     102962460 (CASP8)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     102962460 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     102962460 (CASP8)    05134 Legionellosis     102962460 (CASP8)    05152 Tuberculosis     102962460 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102962460 (CASP8)    05161 Hepatitis B     102962460 (CASP8)    05160 Hepatitis C     102962460 (CASP8)    05164 Influenza A     102962460 (CASP8)    05162 Measles     102962460 (CASP8)    05168 Herpes simplex virus 1 infection     102962460 (CASP8)    05163 Human cytomegalovirus infection     102962460 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     102962460 (CASP8)    05169 Epstein-Barr virus infection     102962460 (CASP8)    05165 Human papillomavirus infection     102962460 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102962460 (CASP8)    05142 Chagas disease     102962460 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102962460 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ptg01002]     102962460 (CASP8) Enzymes [BR:ptg01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      102962460 (CASP8) Peptidases and inhibitors [BR:ptg01002]  Cysteine peptidases   Family C14: caspase family    102962460 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  102962460 NCBI-ProteinID:  XP_007090057 LinkDB All DBs Position Un AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEAMEQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRMSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTNFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagctgggcagtgatgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctgttcaactacctgaac accagcaaggaagcaatggagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaatgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgcggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacaaactttgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccccatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactctgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaggctgattttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccctacggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggcgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctactttcacactgaggaaaaaactcttcttccctcttaattga

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