Panthera tigris altaica (Amur tiger): 102968780 Help Entry 102968780         CDS       T02988                                  Gene name IL6 Definition (RefSeq) interleukin 6   KO K05405   interleukin 6 Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg01521   EGFR tyrosine kinase inhibitor resistance ptg01523   Antifolate resistance ptg04060   Cytokine-cytokine receptor interaction ptg04061   Viral protein interaction with cytokine and cytokine receptor ptg04066   HIF-1 signaling pathway ptg04068   FoxO signaling pathway ptg04151   PI3K-Akt signaling pathway ptg04218   Cellular senescence ptg04620   Toll-like receptor signaling pathway ptg04621   NOD-like receptor signaling pathway ptg04623   Cytosolic DNA-sensing pathway ptg04625   C-type lectin receptor signaling pathway ptg04630   JAK-STAT signaling pathway ptg04640   Hematopoietic cell lineage ptg04657   IL-17 signaling pathway ptg04659   Th17 cell differentiation ptg04668   TNF signaling pathway ptg04672   Intestinal immune network for IgA production ptg04931   Insulin resistance ptg04932   Non-alcoholic fatty liver disease ptg04933   AGE-RAGE signaling pathway in diabetic complications ptg05010   Alzheimer disease ptg05020   Prion disease ptg05022   Pathways of neurodegeneration - multiple diseases ptg05132   Salmonella infection ptg05133   Pertussis ptg05134   Legionellosis ptg05135   Yersinia infection ptg05142   Chagas disease ptg05143   African trypanosomiasis ptg05144   Malaria ptg05146   Amoebiasis ptg05152   Tuberculosis ptg05161   Hepatitis B ptg05162   Measles ptg05163   Human cytomegalovirus infection ptg05164   Influenza A ptg05166   Human T-cell leukemia virus 1 infection ptg05167   Kaposi sarcoma-associated herpesvirus infection ptg05168   Herpes simplex virus 1 infection ptg05169   Epstein-Barr virus infection ptg05171   Coronavirus disease - COVID-19 ptg05200   Pathways in cancer ptg05202   Transcriptional misregulation in cancer ptg05321   Inflammatory bowel disease ptg05323   Rheumatoid arthritis ptg05332   Graft-versus-host disease ptg05410   Hypertrophic cardiomyopathy Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102968780 (IL6)    04668 TNF signaling pathway     102968780 (IL6)    04066 HIF-1 signaling pathway     102968780 (IL6)    04068 FoxO signaling pathway     102968780 (IL6)    04151 PI3K-Akt signaling pathway     102968780 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     102968780 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     102968780 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     102968780 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     102968780 (IL6)    04620 Toll-like receptor signaling pathway     102968780 (IL6)    04621 NOD-like receptor signaling pathway     102968780 (IL6)    04623 Cytosolic DNA-sensing pathway     102968780 (IL6)    04625 C-type lectin receptor signaling pathway     102968780 (IL6)    04659 Th17 cell differentiation     102968780 (IL6)    04657 IL-17 signaling pathway     102968780 (IL6)    04672 Intestinal immune network for IgA production     102968780 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102968780 (IL6)    05202 Transcriptional misregulation in cancer     102968780 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     102968780 (IL6)    05321 Inflammatory bowel disease     102968780 (IL6)    05332 Graft-versus-host disease     102968780 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     102968780 (IL6)    05020 Prion disease     102968780 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     102968780 (IL6)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     102968780 (IL6)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     102968780 (IL6)    04931 Insulin resistance     102968780 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     102968780 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     102968780 (IL6)    05135 Yersinia infection     102968780 (IL6)    05133 Pertussis     102968780 (IL6)    05134 Legionellosis     102968780 (IL6)    05152 Tuberculosis     102968780 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102968780 (IL6)    05161 Hepatitis B     102968780 (IL6)    05171 Coronavirus disease - COVID-19     102968780 (IL6)    05164 Influenza A     102968780 (IL6)    05162 Measles     102968780 (IL6)    05168 Herpes simplex virus 1 infection     102968780 (IL6)    05163 Human cytomegalovirus infection     102968780 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     102968780 (IL6)    05169 Epstein-Barr virus infection     102968780 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     102968780 (IL6)    05144 Malaria     102968780 (IL6)    05142 Chagas disease     102968780 (IL6)    05143 African trypanosomiasis     102968780 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102968780 (IL6)    01523 Antifolate resistance     102968780 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:ptg04052]     102968780 (IL6) Cytokines and growth factors [BR:ptg04052]  Cytokines   Interleukins    102968780 (IL6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 GCSF DUF4924 IL11 IL23 Sec16 Motif Other DBs NCBI-GeneID:  102968780 NCBI-ProteinID:  XP_007089129 LinkDB All DBs Position Un AA seq 233 aa AA seqDB search MSKRNERELHLPSRTPAMTFLSTSAFSPLAFSLGLLLVVANAFPSPGPLGGATPGPLGGD DTSNRLPLTSADKMEELIKYILGKISALKKEMCDNYNKCEDSKEALAENNLNLPKLAEKD GCFQSGFNQETCLTRITTGLQEFQIYLKFLQDKYEGDKENAKSVYTNTNVLLQMLKRKGK NQDEVTIPVPTVEVGLQAKLQSQEEWLRHTTIHLTLRRLEDFLQFSLRAVRIM NT seq 702 nt NT seq  +upstreamnt  +downstreamnt atgtcaaagaggaacgaaagagagctccatctgccctccaggactccagccatgaccttc ctctccacaagcgccttcagtccactcgccttctccctggggctgctcctggtggtggct aacgctttcccttccccgggccccctgggaggagctaccccgggacccctgggaggagat gacacctcaaatagactaccactgacctctgcagacaaaatggaagaactcattaagtac atcctcggcaaaatctctgcactgaaaaaggagatgtgtgacaactataacaaatgtgag gacagcaaggaggcactggcagaaaacaacctaaatcttccgaaactggcagaaaaagat ggatgcttccaatctgggttcaatcaggagacctgcctgacaagaatcactactggtctt caggagtttcagatatacctgaaattcctccaggacaagtatgagggtgataaggaaaat gccaagtctgtatacaccaatactaacgtcctgctccagatgctgaagcgtaagggaaag aatcaggatgaggtaaccatccctgtcccaaccgtagaagttggcctgcaggctaagctg cagtcacaggaagagtggctgaggcacacaacaattcacctcaccctgcgaaggctggag gacttccttcagttcagcctcagggctgttcggataatgtaa

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