KEGG   Pan troglodytes (chimpanzee): 454682
Entry
454682            CDS       T01005                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X8
  KO
K04692  signal transducer and activator of transcription 3
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01521  EGFR tyrosine kinase inhibitor resistance
ptr04062  Chemokine signaling pathway
ptr04066  HIF-1 signaling pathway
ptr04068  FoxO signaling pathway
ptr04217  Necroptosis
ptr04550  Signaling pathways regulating pluripotency of stem cells
ptr04630  JAK-STAT signaling pathway
ptr04659  Th17 cell differentiation
ptr04917  Prolactin signaling pathway
ptr04920  Adipocytokine signaling pathway
ptr04931  Insulin resistance
ptr04933  AGE-RAGE signaling pathway in diabetic complications
ptr04935  Growth hormone synthesis, secretion and action
ptr05145  Toxoplasmosis
ptr05160  Hepatitis C
ptr05161  Hepatitis B
ptr05162  Measles
ptr05163  Human cytomegalovirus infection
ptr05167  Kaposi sarcoma-associated herpesvirus infection
ptr05169  Epstein-Barr virus infection
ptr05200  Pathways in cancer
ptr05203  Viral carcinogenesis
ptr05205  Proteoglycans in cancer
ptr05206  MicroRNAs in cancer
ptr05212  Pancreatic cancer
ptr05221  Acute myeloid leukemia
ptr05223  Non-small cell lung cancer
ptr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ptr05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    454682 (STAT3)
   04066 HIF-1 signaling pathway
    454682 (STAT3)
   04068 FoxO signaling pathway
    454682 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    454682 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    454682 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    454682 (STAT3)
   04062 Chemokine signaling pathway
    454682 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    454682 (STAT3)
   04917 Prolactin signaling pathway
    454682 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    454682 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    454682 (STAT3)
   05206 MicroRNAs in cancer
    454682 (STAT3)
   05205 Proteoglycans in cancer
    454682 (STAT3)
   05203 Viral carcinogenesis
    454682 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    454682 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    454682 (STAT3)
   05221 Acute myeloid leukemia
    454682 (STAT3)
   05223 Non-small cell lung cancer
    454682 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    454682 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    454682 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    454682 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    454682 (STAT3)
   05161 Hepatitis B
    454682 (STAT3)
   05160 Hepatitis C
    454682 (STAT3)
   05163 Human cytomegalovirus infection
    454682 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    454682 (STAT3)
   05169 Epstein-Barr virus infection
    454682 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    454682 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    454682 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ptr03000]
    454682 (STAT3)
Transcription factors [BR:ptr03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    454682 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 454682
NCBI-ProteinID: XP_001165274
Ensembl: ENSPTRG00000009200
VGNC: 9663
UniProt: K7DE52
LinkDB
Position
17
AA seq 722 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPFIDAV
WK
NT seq 2169 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagcttgacacacggtacctggagcagctccatcag
ctctacagtgacagcttcccaatggagctgcggcagtttctggccccttggattgagagt
caagattgggcatatgcggccagcaaagaatcacatgccactttggtgtttcataatctc
ctgggagagattgaccagcagtatagccgcttcctgcaagagtcgaatgttctctatcag
cacaatctacgaagaatcaagcagtttcttcagagcaggtatcttgagaagccaatggag
attgcccggattgtggcccggtgcctgtgggaagaatcacgccttctacagactgcagcc
actgcggcccagcaagggggccaggccaaccaccccacagcagctgtggtgacggagaag
cagcagatgctggagcagcaccttcaggatgtccggaagagagtgcaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaagatctgaatggaaacaaccagtcagtgaccaggcagaagatg
cagcagctggaacagatgctcactgcgctggaccagatgcggagaagcatcgtgagtgag
ctggcggggcttttgtcagcgatggagtacgtgcagaaaactctcacggacgaggagctg
gctgactggaagaggcggcaacagattgcctgcattggaggcccgcccaacatctgccta
gatcggctagaaaactggataacgtcattagcagaatctcaacttcagactcgtcaacaa
attaagaaactggaggagttgcagcaaaaagtttcctacaaaggggaccccattgtacag
caccggccgatgctggaggagagaatcgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggtggagcggcagccctgcatgcccatgcatcctgaccggcccctcgtcatcaag
accggcgtccagttcactactaaagtcaggttgctggtcaaattccctgagttgaattat
cagcttaaaattaaagtgtgcattgacaaagactctggggacgttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagaatccaac
aacggcagcctctctgcagaattcaaacacttgaccctgagggagcagagatgtgggaat
gggggccgagccaattgtgatgcttccctgattgtgactgaggagctgcacctgatcacc
tttgagaccgaggtgtatcaccaaggcctcaagattgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcgtccatcctgtggtac
aacatgctgaccaacaatcccaagaacgtaaacttttttaccaagcccccaattggaacc
tgggatcaagtggccgaggtcctgagctggcagttctcctccaccaccaagcgaggactg
agcatcgagcagctgactacactggcagagaaactcttgggacctggtgtgaattattca
gggtgtcagatcacatgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaatatcattgaccttgtgaaaaagtacatcctggccctttgg
aacgaagggtacatcatgggctttatcagtaaggagcgggagcgggccatcttgagcact
aagcctccaggcaccttcctgctaagattcagtgaaagcagcaaagaaggaggcgtcact
ttcacctgggtggagaaggacatcagcggtaagacccagatccagtccgtggaaccatac
acaaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gatgctaccaatatcctggtgtctccactggtctatctctatcctgacattcccaaggag
gaggcattcggaaagtattgtcggccagagagccaggagcatcctgaagctgacccaggt
agcgctgccccatacctgaagaccaagtttatctgtgtgacaccattcattgatgcagtt
tggaaataa

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