Pan troglodytes (chimpanzee): 454832
Help
Entry
454832 CDS
T01005
Gene name
PRKCA
Definition
(RefSeq) protein kinase C alpha type isoform X2
KO
K02677
classical protein kinase C alpha type [EC:
2.7.11.13
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01521
EGFR tyrosine kinase inhibitor resistance
ptr04010
MAPK signaling pathway
ptr04012
ErbB signaling pathway
ptr04014
Ras signaling pathway
ptr04015
Rap1 signaling pathway
ptr04020
Calcium signaling pathway
ptr04066
HIF-1 signaling pathway
ptr04070
Phosphatidylinositol signaling system
ptr04071
Sphingolipid signaling pathway
ptr04072
Phospholipase D signaling pathway
ptr04150
mTOR signaling pathway
ptr04151
PI3K-Akt signaling pathway
ptr04261
Adrenergic signaling in cardiomyocytes
ptr04270
Vascular smooth muscle contraction
ptr04310
Wnt signaling pathway
ptr04360
Axon guidance
ptr04370
VEGF signaling pathway
ptr04510
Focal adhesion
ptr04540
Gap junction
ptr04650
Natural killer cell mediated cytotoxicity
ptr04664
Fc epsilon RI signaling pathway
ptr04666
Fc gamma R-mediated phagocytosis
ptr04670
Leukocyte transendothelial migration
ptr04713
Circadian entrainment
ptr04720
Long-term potentiation
ptr04723
Retrograde endocannabinoid signaling
ptr04724
Glutamatergic synapse
ptr04725
Cholinergic synapse
ptr04726
Serotonergic synapse
ptr04727
GABAergic synapse
ptr04728
Dopaminergic synapse
ptr04730
Long-term depression
ptr04750
Inflammatory mediator regulation of TRP channels
ptr04911
Insulin secretion
ptr04912
GnRH signaling pathway
ptr04916
Melanogenesis
ptr04918
Thyroid hormone synthesis
ptr04919
Thyroid hormone signaling pathway
ptr04921
Oxytocin signaling pathway
ptr04925
Aldosterone synthesis and secretion
ptr04926
Relaxin signaling pathway
ptr04928
Parathyroid hormone synthesis, secretion and action
ptr04929
GnRH secretion
ptr04933
AGE-RAGE signaling pathway in diabetic complications
ptr04935
Growth hormone synthesis, secretion and action
ptr04960
Aldosterone-regulated sodium reabsorption
ptr04961
Endocrine and other factor-regulated calcium reabsorption
ptr04970
Salivary secretion
ptr04971
Gastric acid secretion
ptr04972
Pancreatic secretion
ptr05017
Spinocerebellar ataxia
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05031
Amphetamine addiction
ptr05032
Morphine addiction
ptr05143
African trypanosomiasis
ptr05146
Amoebiasis
ptr05161
Hepatitis B
ptr05163
Human cytomegalovirus infection
ptr05164
Influenza A
ptr05170
Human immunodeficiency virus 1 infection
ptr05171
Coronavirus disease - COVID-19
ptr05200
Pathways in cancer
ptr05205
Proteoglycans in cancer
ptr05206
MicroRNAs in cancer
ptr05214
Glioma
ptr05223
Non-small cell lung cancer
ptr05225
Hepatocellular carcinoma
ptr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
454832 (PRKCA)
04012 ErbB signaling pathway
454832 (PRKCA)
04014 Ras signaling pathway
454832 (PRKCA)
04015 Rap1 signaling pathway
454832 (PRKCA)
04310 Wnt signaling pathway
454832 (PRKCA)
04370 VEGF signaling pathway
454832 (PRKCA)
04066 HIF-1 signaling pathway
454832 (PRKCA)
04020 Calcium signaling pathway
454832 (PRKCA)
04070 Phosphatidylinositol signaling system
454832 (PRKCA)
04072 Phospholipase D signaling pathway
454832 (PRKCA)
04071 Sphingolipid signaling pathway
454832 (PRKCA)
04151 PI3K-Akt signaling pathway
454832 (PRKCA)
04150 mTOR signaling pathway
454832 (PRKCA)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
454832 (PRKCA)
04540 Gap junction
454832 (PRKCA)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
454832 (PRKCA)
04664 Fc epsilon RI signaling pathway
454832 (PRKCA)
04666 Fc gamma R-mediated phagocytosis
454832 (PRKCA)
04670 Leukocyte transendothelial migration
454832 (PRKCA)
09152 Endocrine system
04911 Insulin secretion
454832 (PRKCA)
04929 GnRH secretion
454832 (PRKCA)
04912 GnRH signaling pathway
454832 (PRKCA)
04921 Oxytocin signaling pathway
454832 (PRKCA)
04926 Relaxin signaling pathway
454832 (PRKCA)
04935 Growth hormone synthesis, secretion and action
454832 (PRKCA)
04918 Thyroid hormone synthesis
454832 (PRKCA)
04919 Thyroid hormone signaling pathway
454832 (PRKCA)
04928 Parathyroid hormone synthesis, secretion and action
454832 (PRKCA)
04916 Melanogenesis
454832 (PRKCA)
04925 Aldosterone synthesis and secretion
454832 (PRKCA)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
454832 (PRKCA)
04270 Vascular smooth muscle contraction
454832 (PRKCA)
09154 Digestive system
04970 Salivary secretion
454832 (PRKCA)
04971 Gastric acid secretion
454832 (PRKCA)
04972 Pancreatic secretion
454832 (PRKCA)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
454832 (PRKCA)
04961 Endocrine and other factor-regulated calcium reabsorption
454832 (PRKCA)
09156 Nervous system
04724 Glutamatergic synapse
454832 (PRKCA)
04727 GABAergic synapse
454832 (PRKCA)
04725 Cholinergic synapse
454832 (PRKCA)
04728 Dopaminergic synapse
454832 (PRKCA)
04726 Serotonergic synapse
454832 (PRKCA)
04720 Long-term potentiation
454832 (PRKCA)
04730 Long-term depression
454832 (PRKCA)
04723 Retrograde endocannabinoid signaling
454832 (PRKCA)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
454832 (PRKCA)
09158 Development and regeneration
04360 Axon guidance
454832 (PRKCA)
09159 Environmental adaptation
04713 Circadian entrainment
454832 (PRKCA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
454832 (PRKCA)
05206 MicroRNAs in cancer
454832 (PRKCA)
05205 Proteoglycans in cancer
454832 (PRKCA)
05231 Choline metabolism in cancer
454832 (PRKCA)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
454832 (PRKCA)
05214 Glioma
454832 (PRKCA)
05223 Non-small cell lung cancer
454832 (PRKCA)
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
454832 (PRKCA)
05022 Pathways of neurodegeneration - multiple diseases
454832 (PRKCA)
09165 Substance dependence
05031 Amphetamine addiction
454832 (PRKCA)
05032 Morphine addiction
454832 (PRKCA)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
454832 (PRKCA)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
454832 (PRKCA)
05161 Hepatitis B
454832 (PRKCA)
05171 Coronavirus disease - COVID-19
454832 (PRKCA)
05164 Influenza A
454832 (PRKCA)
05163 Human cytomegalovirus infection
454832 (PRKCA)
09174 Infectious disease: parasitic
05146 Amoebiasis
454832 (PRKCA)
05143 African trypanosomiasis
454832 (PRKCA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
454832 (PRKCA)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.13 protein kinase C
454832 (PRKCA)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: AGC group
PKC family [OT]
454832 (PRKCA)
Membrane trafficking [BR:
ptr04131
]
Endocytosis
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
454832 (PRKCA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
C1_1
C2
Pkinase_C
C1_2
APH
Motif
Other DBs
NCBI-GeneID:
454832
NCBI-ProteinID:
XP_003315734
Ensembl:
ENSPTRG00000009557
VGNC:
12611
UniProt:
H2QDQ1
LinkDB
All DBs
Position
17
AA seq
672 aa
AA seq
DB search
MADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME
LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG
TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV
NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA
DFGMCKEHMMVGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG
EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI
DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN
PQFVHPILQSAV
NT seq
2019 nt
NT seq
+upstream
nt +downstream
nt
atggctgacgttttcccgggcaacgactccacggcgtctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcgcgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggtccacaagaggtgccatgaa
tttgttactttttcttgtccgggtgcggataagggacccgacactgatgaccccaggagc
aagcacaagttcaaaatccacacttacggaagccccaccttctgcgatcactgtgggtca
ctgctctatggacttatccatcaagggatgaaatgtgacacctgcgatatgaacgttcac
aagcaatgcgtcatcaatgtccccagcctctgcggaatggatcacactgagaagaggggg
cggatttacctaaaggctgaggttgctgatgaaaagctccatgtcacagtacgagatgca
aaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaactt
attcctgatcccaagaatgaaagcaagcaaaaaaccaaaaccatccgctccacactaaat
ccacagtggaatgagtcctttacattcaaattgaaaccttcagacaaagaccgacgactg
tctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatccctttcc
tttggagtttcggagctgatgaagatgccggccagtggatggtacaagttgcttaaccaa
gaagaaggtgagtactacaatgtacccattccggaaggggacgaagaaggaaacatggaa
ctcaggcagaaattcgagaaagccaaacttggccctgctggcaacaaagtcatcagtccc
tctgaagacaggaaacaaccttccaacaaccttgaccgagtgaaactcacggacttcaat
ttcctcatggtgttgggaaaggggagttttggaaaggtgatgcttgccgacaggaagggc
acagaagaactgtatgcaatcaaaatcctgaagaaggatgtggtgattcaggatgatgac
gtggagtgcaccatggtagaaaagcgagtcttggccctgcttgacaaacccccgttcttg
acgcagctgcactcctgcttccagacagtggatcggctgtacttcgtcatggaatatgtc
aacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagca
gtattctatgcagcagagatttccatcggattgttctttcttcataaaagaggaatcatt
tacagggatctgaagttagataacgtcatgttggattcagaaggacatatcaaaattgct
gactttgggatgtgcaaggaacacatgatggttggagtcacgaccaggaccttctgtggg
actccagattatatcgccccagagataatcgcttatcagccgtatggaaaatctgtggac
tggtgggcctatggcgtcctgttgtatgaaatgcttgccgggcagcctccatttgatggt
gaagatgaagacgagctatttcagtctatcatggagcacaacgtttcctatccaaaatcc
ttgtccaaggaggctgtttctatctgcaaaggactgatgaccaaacacccagccaagcgg
ctgggctgtgggcctgagggggagagggacgtgagagaacatgccttcttccggaggatc
gactgggaaaaactggagaacagggagatccagccaccattcaagcccaaagtgtgcggc
aaaggagcagagaactttgacaagttcttcacacgaggacagcccgtcttaacaccgcct
gatcagctggttattgctaacatagaccagtctgattttgaagggttctcgtatgtcaac
ccccagtttgtgcaccccatcttacagagtgcagtatga
DBGET
integrated database retrieval system
