Pan troglodytes (chimpanzee): 456715
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Entry
456715 CDS
T01005
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04064
NF-kappa B signaling pathway
ptr04380
Osteoclast differentiation
ptr04650
Natural killer cell mediated cytotoxicity
ptr04658
Th1 and Th2 cell differentiation
ptr04659
Th17 cell differentiation
ptr04660
T cell receptor signaling pathway
ptr05135
Yersinia infection
ptr05166
Human T-cell leukemia virus 1 infection
ptr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ptr05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
456715 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
456715 (LCK)
04660 T cell receptor signaling pathway
456715 (LCK)
04658 Th1 and Th2 cell differentiation
456715 (LCK)
04659 Th17 cell differentiation
456715 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
456715 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
456715 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
456715 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
456715 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
456715 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
456715 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ptr03036
]
456715 (LCK)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
456715 (LCK)
Protein kinases [BR:
ptr01001
]
Non-receptor tyrosine kinases
SRC family
456715 (LCK)
Chromosome and associated proteins [BR:
ptr03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
456715 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
SH3_16
SH3_3
ABC1
Motif
Other DBs
NCBI-GeneID:
456715
NCBI-ProteinID:
XP_016813760
Ensembl:
ENSPTRG00000000479
VGNC:
11499
LinkDB
All DBs
Position
1:31011418..31046428
Genome browser
AA seq
615 aa
AA seq
DB search
MGIPGSHNLSPLSIPSGTMGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGS
EVRDPLVTYEGSNPPASPLQGDPRQQGLKDKACGSLAVGFHLSPTYFLPGLAFLVPHPVT
PGFLPIPARFSLMPLVFTDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLT
TGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFS
LSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPC
QTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA
FLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQ
QLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSD
TLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIV
THGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVL
EDFFTATEGQYQPQP
NT seq
1848 nt
NT seq
+upstream
nt +downstream
nt
atggggatcccaggatctcacaatctcagccccctctccattccctcagggaccatgggc
tgtggctgcagctcacacccggaagatgactggatggaaaacatcgatgtgtgtgagaac
tgccattatcccatagtcccactggacggcaagggaacgctgctcatccgaaatggctct
gaggtgcgggacccactggttacctacgaaggctccaatccgccggcttccccactgcaa
ggtgaccccaggcagcagggcctgaaagacaaggcctgcggatccctggctgttggcttc
cacctctcccccacctactttctccccggtcttgccttccttgtcccccaccctgtaact
ccaggcttcctgcccatcccagcccggttctccctgatgccccttgtctttacagacaac
ctggttatcgctctgcacagctatgagccctctcacgacggagatctgggctttgagaag
ggggaacagctccgcatcctggagcagagcggcgagtggtggaaggcgcagtccctgacc
acgggccaggaaggcttcatccccttcaattttgtggccaaagcgaacagcctggagccc
gaaccctggttcttcaagaacctgagccgcaaggacgcggagcggcagctcctggcgccc
gggaacactcacggctccttcctcatccgggagagcgagagcaccgcgggatcgttttca
ctgtcggtccgggacttcgaccagaaccagggagaggtggtgaaacattacaagatccgt
aatctggacaacggtggcttctacatctcccctcgaatcacttttcccggcctgcatgaa
ctggtccgccattacaccaatgcttcagatgggctgtgcacacggttgagccgcccctgc
cagacccagaagccccagaagccgtggtgggaggacgagtgggaggttcccagggagacg
ctgaagctggtggagcggctgggggctggacagttcggggaggtgtggatggggtactac
aacgggcacacgaaggtggcggtgaagagcctgaagcagggcagcatgtccccggacgcc
ttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctggttcggctctat
gctgtggtcacccaggagcccatctacatcatcactgaatacatggagaatgacacactt
ctagactcccagttggaggagaaaggtctgggggcctccccctggggcaacttgggccag
caactcttgcttctgcccacagggagtctagtggattttctcaagaccccttcaggcatc
aagttgaccatcaacaaactcctggacatggcagcccaaattgcagaaggcatggcattc
attgaagagcggaattatattcatcgtgaccttcgggctgccaacattctggtgtctgac
accctgagctgcaagattgcagactttggcctagcacgcctcattgaggacaacgagtac
acagccagggagggggccaagtttcccattaagtggacagcgccagaagccattaactac
gggacattcaccatcaagtcagatgtgtggtcttttgggatcctgctgacggaaattgtc
acccacggccgcatcccttacccagggatgaccaacccggaggtgattcagaacctggag
cgaggctaccgcatggtgcgccctgacaactgtccagaggagctgtaccaactcatgagg
ctgtgctggaaggagcgcccagaggaccggcccacctttgactacctgcgcagtgtgctg
gaggacttcttcacggccacagagggccagtaccagcctcagccttga
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