KEGG   Pan troglodytes (chimpanzee): 457477Help
Entry
457477            CDS       T01005                                 

Gene name
MGST3
Definition
(RefSeq) microsomal glutathione S-transferase 3
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00480  Glutathione metabolism
ptr00980  Metabolism of xenobiotics by cytochrome P450
ptr00982  Drug metabolism - cytochrome P450
ptr00983  Drug metabolism - other enzymes
ptr01524  Platinum drug resistance
ptr05200  Pathways in cancer
ptr05204  Chemical carcinogenesis
ptr05225  Hepatocellular carcinoma
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    457477 (MGST3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    457477 (MGST3)
   00982 Drug metabolism - cytochrome P450
    457477 (MGST3)
   00983 Drug metabolism - other enzymes
    457477 (MGST3)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    457477 (MGST3)
   05204 Chemical carcinogenesis
    457477 (MGST3)
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    457477 (MGST3)
  09166 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    457477 (MGST3)
  09176 Drug resistance: Antineoplastic
   01524 Platinum drug resistance
    457477 (MGST3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ptr02000]
    457477 (MGST3)
Enzymes [BR:ptr01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     457477 (MGST3)
Transporters [BR:ptr02000]
 Other Transporters
  Pores ion channels [TC:1]
   457477 (MGST3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MAPEG
Motif
Other DBs
NCBI-GeneID: 457477
NCBI-ProteinID: XP_001174626
Ensembl: ENSPTRG00000001616
VGNC: 6916
UniProt: K7BTG1
LinkDB All DBs
Position
1
AA seq 151 aa AA seqDB search
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA
HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI
ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCH
NT seq 456 nt NT seq  +upstreamnt  +downstreamnt
atggctgtcctctctaaggaatatggttttgtgcttctaactggtgctgccagctttata
atggtggcccacctagccatcaatgtttccaaggcccgcaagaagtacaaagtggagtat
cctatcatgtacagcacggaccctgaaaatgggcacatcttcaactgcattcagcgagcc
caccagaacacgttggaagtgtatcctcccttcttattttttctagctgttggaggtgtt
taccacccgcgtatagcttctggcctgggcttggcctggattgttggacgagttctttat
gcttatggctattacacaggagaacccagcaagcgtagtcgaggagccctggggtccatc
gccctcctgggcttggtgggcacaactgtgtgctctgctttccagcatcttggttgggtt
aaaagtggcttgggcagtggacccaaatgccattaa

DBGET integrated database retrieval system