Pan troglodytes (chimpanzee): 462944
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Entry
462944 CDS
T01005
Gene name
FYN
Definition
(RefSeq) tyrosine-protein kinase Fyn isoform X1
KO
K05703
tyrosine-protein kinase Fyn [EC:
2.7.10.2
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04071
Sphingolipid signaling pathway
ptr04072
Phospholipase D signaling pathway
ptr04360
Axon guidance
ptr04380
Osteoclast differentiation
ptr04510
Focal adhesion
ptr04520
Adherens junction
ptr04611
Platelet activation
ptr04650
Natural killer cell mediated cytotoxicity
ptr04660
T cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04725
Cholinergic synapse
ptr05020
Prion disease
ptr05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
462944 (FYN)
04071 Sphingolipid signaling pathway
462944 (FYN)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
462944 (FYN)
04520 Adherens junction
462944 (FYN)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
462944 (FYN)
04650 Natural killer cell mediated cytotoxicity
462944 (FYN)
04660 T cell receptor signaling pathway
462944 (FYN)
04664 Fc epsilon RI signaling pathway
462944 (FYN)
09156 Nervous system
04725 Cholinergic synapse
462944 (FYN)
09158 Development and regeneration
04360 Axon guidance
462944 (FYN)
04380 Osteoclast differentiation
462944 (FYN)
09160 Human Diseases
09164 Neurodegenerative disease
05020 Prion disease
462944 (FYN)
09166 Cardiovascular disease
05416 Viral myocarditis
462944 (FYN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
462944 (FYN)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ptr04131
]
462944 (FYN)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
462944 (FYN)
Protein kinases [BR:
ptr01001
]
Non-receptor tyrosine kinases
SRC family
462944 (FYN)
Membrane trafficking [BR:
ptr04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
462944 (FYN)
Endocytosis
Lipid raft mediated endocytosis
Flotillin-dependent endocytosis
462944 (FYN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH3_10
SH3_3
zf-RING_14
Motif
Other DBs
NCBI-GeneID:
462944
NCBI-ProteinID:
XP_001159342
Ensembl:
ENSPTRG00000018511
VGNC:
9963
UniProt:
A0A2I3SKP4
A0A6D2Y4M7
LinkDB
All DBs
Position
6
AA seq
537 aa
AA seq
DB search
MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQG
LTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWW
EARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESET
TKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCC
RLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKT
LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGR
ALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE
RGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL
NT seq
1614 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgtgcaatgtaaggataaagaagcaacaaaactgacggaggagagggacggc
agcctgaaccagagctctgggtaccgctatggcacagaccccacccctcagcactacccc
agcttcggcgtgacctccatccccaactacaacaacttccatgcagccgggggccaagga
ctcaccgtctttggaggtgtgaactcttcgtctcatacggggaccttgcgtacgagagga
ggaacaggagtgacactctttgtggccctttatgactatgaagcacggacagaagatgac
ctaagttttcacaaaggagaaaaatttcaaatattgaacagctcggaaggagattggtgg
gaagcccgctccttgacaactggagagacaggttacattcccagcaattatgtggctcca
gttgactctatccaggcagaagagtggtactttggaaaacttggccgaaaagatgctgag
cgacagctattgtcctttggaaacccaagaggtacctttcttatccgcgagagtgaaacc
accaaaggtgcctattcactttctatccgtgattgggatgatatgaaaggagaccatgtc
aaacattataaaattcgcaaacttgacaatggtggatactacattaccacccgggcccag
tttgaaacacttcagcagcttgtacaacattactcagagagagctgcaggtctctgctgc
cgcctagtagttccctgtcacaaagggatgccaaggcttaccgatctgtctgtcaaaacc
aaagatgtctgggaaatccctcgagaatccctgcagttgatcaagagactgggaaatggg
cagtttggggaagtatggatgggtacctggaatggaaacacaaaagtagccataaagact
cttaaaccaggcacaatgtcccccgaatcattccttgaggaagcgcagatcatgaagaag
ctgaagcacgacaagctggtccagctctatgcagtggtgtctgaggagcccatctacatc
gtcaccgagtatatgaacaaaggaagtttactggatttcttaaaagatggagaaggaaga
gctctgaaattaccaaatcttgtggacatggcagcacaggtggctgcaggaatggcttac
atcgagcgcatgaattatatccatagagatctgcgatcagcaaacattctagtggggaat
ggactcatatgcaagattgctgacttcggattggcccgattgatcgaagacaatgagtac
acagcaagacaaggtgcaaagttccccatcaagtggacggcccccgaggcagccctgtac
gggaggttcacaatcaagtctgacgtgtggtcttttggaatcttactcacagagctggtc
accaaaggaagagtgccatacccaggcatgaacaaccgggaggtgctggagcaggtcgag
cgaggctacaggatgccctgcccgcaggactgccccatctctctgcatgagctcatgatc
cactgctggaaaaaggaccctgaagaacgccccacttttgagtacttgcagagcttcctg
gaagactactttaccgcgacagagccccagtaccaacctggtgaaaacctgtaa
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