KEGG   Pan troglodytes (chimpanzee): 469481Help
Entry
469481            CDS       T01005                                 

Gene name
SETDB1
Definition
(RefSeq) histone-lysine N-methyltransferase SETDB1 isoform X1
  KO
K11421  histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00310  Lysine degradation
ptr04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    469481 (SETDB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    469481 (SETDB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ptr03036]
    469481 (SETDB1)
Enzymes [BR:ptr01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     469481 (SETDB1)
Chromosome and associated proteins [BR:ptr03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     469481 (SETDB1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    469481 (SETDB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SET Pre-SET MBD DUF4537
Motif
Other DBs
NCBI-GeneID: 469481
NCBI-ProteinID: XP_016782178
Ensembl: ENSPTRG00000001267
VGNC: 8102
LinkDB All DBs
Position
1
AA seq 1306 aa AA seqDB search
MCEVFGLWILEDKSMSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDE
ELEKMDCVQQRKKQLAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQ
YRDSSSEDESSRPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQK
FMDAVNKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGP
GKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPN
VKNKLRFLIFFDDGYASYVTQSELYPICRPLTKTWEDIEDISCRDFIEEYVTAYPNRPMV
LLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSA
SALEKKQGQLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPP
LSPQAGDSESLESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQT
YRSPLGSTASAPAPSALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSR
VRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYL
FETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQV
AYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGY
QYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAK
GSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDL
KDQEDGNSGTEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSK
DSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFK
TNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNP
SPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSA
TAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASV
DKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFP
WVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
NT seq 3921 nt NT seq  +upstreamnt  +downstreamnt
atgtgtgaagtatttggattgtggatattagaggacaaaagcatgtcttcccttcctggg
tgcattggtttggatgcagcaacagctacagtggagtctgaagagattgcagagctgcaa
caggcagtggttgaggaactgggtatctctatggaggaacttcggcatttcatcgatgag
gaactggagaagatggattgtgtacagcaacgcaagaagcagctagcagagttagagacg
tgggtaatacagaaagaatctgaggtggctcacgttgaccaactctttgatgatgcatcc
agggcagtgactaattgtgagtctttggtgaaggacttctactccaagctgggactacaa
taccgggacagtagctctgaggacgaatcttcccggcctacagaaataattgagattcct
gatgaagatgatgatgtcctcagtattgattcaggtgatgctgggagcagaactccaaaa
gaccagaagctccgtgaagctatggctgccttaagaaagtcagctcaagatgttcagaag
ttcatggatgctgtcaacaagaagagcagttcccaggatctgcataaaggaaccttgagt
cagatgtctggagaactaagcaaagatggtgacctgatagtcagcatgcgaattctgggc
aagaagagaactaagacttggcacaaaggcacccttattgccatccagacagttgggcca
gggaagaaatacaaggtgaaatttgacaacaaaggaaagagtctactgtcggggaaccat
attgcctatgattaccaccctcctgctgacaagctgtatgtgggcagtcgggtggtcgcc
aaatacaaagatgggaatcaggtctggctctatgctggcattgtagctgagacaccaaac
gtcaaaaacaagctcaggtttctcattttctttgatgatggctatgcttcctatgtcaca
cagtcggaactgtatcccatttgccggccactgacaaagacttgggaggacatagaagac
atctcctgccgtgacttcatagaggagtatgtcactgcctaccccaaccgccccatggta
ctgctcaagagtggccagcttatcaagactgagtgggaaggcacgtggtggaagtcccga
gttgaggaggtggatggcagcctagtcaggatcctcttcctggatgacaaaagatgtgag
tggatctatcgaggctctacacggctggagcccatgttcagcatgaaaacatcctcagcc
tctgcactggagaagaagcaaggacagctcaggacacgtccaaatatgggtgctgtgagg
agcaaaggccctgttgtccagtacacacaggatctgactggtactggaacccagttcaag
ccagtggaacccccacagcctacagctccacctgccccacctttcccacctgctccacct
ctatccccccaagcaggtgacagtgaaagcttggaaagccagcttgcccagtcacggaag
caggtagccaaaaagagcacgtcctttcgaccaggatctgtgggctctggtcattcctcc
cctacatctcctgcactcagtgaaaatgtctctggtgggaaacctgggatcaaccagaca
tatagatcacctttaggctccacagcctctgccccggcaccctcagcactcccagcccct
ccagcacccccagtcttccatggcatgctggagcgggccccagcagagccctcctaccgt
gctcccatggagaagcttttctacttacctcatgtctgcagctatacctgtctgtctcga
gtcagacctatgaggaatgagcagtaccggggcaagaaccctctgctggtcccattactg
tatgacttccggcggatgacagcccggcgtcgagttaaccgcaagatgggctttcatgtt
atctataagacaccttgtggtctctgccttcggacaatgcaggagatagaacgctacctt
ttcgagactggctgtgacttcctcttcctggagatgttctgtttggatccatatgttctt
gtggaccgaaagtttcagccctataagcctttttactatattttggacatcacttatggg
aaggaagatgttcccctatcctgtgtcaatgagattgacacaacccctccaccccaggtg
gcctacagcaaggaacgtatcccgggcaagggtgttttcattaacacaggccctgaattt
ctggttggctgtgactgcaaggatgggtgtcgggacaagtccaagtgtgcctgccatcaa
ctaactatccaggctacagcctgtaccccaggaggccaaatcaaccctaactctggctac
cagtacaagagactagaagagtgtctacccacaggggtatatgagtgtaacaaacgctgc
aaatgtgacccaaacatgtgcacaaaccggttggtgcaacatggactacaagttcggcta
cagctattcaagacacagaacaagggctggggtatccgctgcttggatgacattgccaaa
ggctcttttgtttgtatttatgcaggcaaaatcctgacagatgactttgcagacaaggag
ggtctggaaatgggtgatgagtactttgcaaatctggaccatatcgagagcgtggagaac
ttcaaagaaggatatgagagtgatgccccctgttcctctgacagcagtggtgtagacttg
aaggaccaggaagatggcaacagcggtacagaggaccctgaagagtccaatgatgatagc
tcagatgataacttctgtaaggatgaggacttcagcaccagttcagtgtggcggagctat
gctacccggaggcagacccggggccagaaagagaacggactctctgagacaacttccaag
gactcccaccccccagatcttggacccccacatattcctgttcctccctcaatccctgta
ggtggctgcaatccaccttcctccgaagagacacccaagaacaaggtggcctcatggttg
agctgcaatagtgtcagtgaaggtggttttgctgactctgatagccattcatccttcaag
actaatgaaggtggggagggccgggctgggggaagccgaatggaggctgagaaggcctcc
acctcaggactaggcatcaaggatgagggagacatcaaacaggccaagaaagaggacact
gacgaccgaaacaagatgtcagtagttactgaaagctctcgaaattacggttacaatcct
tctcctgtgaagcctgaaggacttcgccgcccacctagtaagactagtatgcatcaaagc
cgaagactcatggcttctgctcagtccaaccctgatgatgtcctgacactgtccagcagc
acagaaagtgagggggaaagtgggaccagccgaaagcccactgctggtcagacttcggct
acagcggttgacagtgatgatatccagaccatatcctctggctctgaaggggatgacttt
gaggacaagaagaacatgactggtccaatgaagcgtcaagtggcagtaaaatcaacccga
ggctttgctcttaaatcaacccatgggattgcaattaaatcaaccaacatggcctctgtg
gacaagggggagagcgcacctgttcgtaagaacacacgccaattctatgatggcgaggag
tcttgctacatcattgatgccaagcttgaaggcaacctgggccgctacctcaaccacagt
tgcagccccaacctgtttgtccagaatgtcttcgtggatacccatgatcttcgcttcccc
tgggtggccttctttgccagcaaaagaatccgggctgggacagaacttacttgggactac
aactacgaggtgggcagtgtggaaggcaaggagctactctgttgctgtggggccattgaa
tgcagaggacgtcttctttag

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