KEGG   Pan troglodytes (chimpanzee): 472992
Entry
472992            CDS       T01005                                 

Gene name
TGFBR1
Definition
(RefSeq) TGF-beta receptor type-1 isoform X2
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04010  MAPK signaling pathway
ptr04060  Cytokine-cytokine receptor interaction
ptr04068  FoxO signaling pathway
ptr04144  Endocytosis
ptr04218  Cellular senescence
ptr04350  TGF-beta signaling pathway
ptr04371  Apelin signaling pathway
ptr04380  Osteoclast differentiation
ptr04390  Hippo signaling pathway
ptr04520  Adherens junction
ptr04659  Th17 cell differentiation
ptr04926  Relaxin signaling pathway
ptr04933  AGE-RAGE signaling pathway in diabetic complications
ptr05142  Chagas disease
ptr05161  Hepatitis B
ptr05166  Human T-cell leukemia virus 1 infection
ptr05200  Pathways in cancer
ptr05210  Colorectal cancer
ptr05212  Pancreatic cancer
ptr05220  Chronic myeloid leukemia
ptr05225  Hepatocellular carcinoma
ptr05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    472992 (TGFBR1)
   04350 TGF-beta signaling pathway
    472992 (TGFBR1)
   04390 Hippo signaling pathway
    472992 (TGFBR1)
   04371 Apelin signaling pathway
    472992 (TGFBR1)
   04068 FoxO signaling pathway
    472992 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    472992 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    472992 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    472992 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    472992 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    472992 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    472992 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    472992 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    472992 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    472992 (TGFBR1)
   05212 Pancreatic cancer
    472992 (TGFBR1)
   05225 Hepatocellular carcinoma
    472992 (TGFBR1)
   05226 Gastric cancer
    472992 (TGFBR1)
   05220 Chronic myeloid leukemia
    472992 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    472992 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    472992 (TGFBR1)
   05161 Hepatitis B
    472992 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    472992 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptr01001]
    472992 (TGFBR1)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     472992 (TGFBR1)
Protein kinases [BR:ptr01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   472992 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2
Other DBs
NCBI-GeneID: 472992
NCBI-ProteinID: XP_001159299
Ensembl: ENSPTRG00000021182
VGNC: 4876
UniProt: K7B517
LinkDB
Position
9
AA seq 503 aa
MEAAAAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTE
TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPG
LGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDL
IYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREER
SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVE
GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDS
ATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGI
HEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGA
ARLTALRIKKTLSQLSQQEGIKM
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggaggcggcggccgctgctccgcgtccccggctgctcctcctcgtgctggcggcggcg
gcggcggcggcggcggcactgctcccgggggcgacggcgttacagtgtttctgccacctc
tgtacaaaagacaattttacttgtgtgacagatgggctctgctttgtctctgtcacagag
accacagacaaagttatacacaacagcatgtgtatagctgaaattgacttaattcctcga
gataggccgtttgtatgtgcaccctcttcaaaaactgggtctgtgactacaacatattgc
tgcaatcaggaccattgcaataaaatagaacttccaactactgtaaagtcatcacctggc
cttggtcctgtggaactggcagctgtcattgctggaccagtgtgcttcgtctgcatctca
ctcatgttgatggtctatatctgccacaaccgcactgtcattcaccatcgagtgccaaat
gaagaggacccttcattagatcgcccttttatttcagagggtactacgttgaaagactta
atttatgatatgacaacgtcaggttctggctcaggtttaccattgcttgttcagagaaca
attgcgagaactattgtgttacaagaaagcattggcaaaggtcgatttggagaagtttgg
agaggaaagtggcggggagaagaagttgctgttaagatattctcctctagagaagaacgt
tcgtggttccgtgaggcagagatttatcaaactgtaatgttacgtcatgaaaacatcctg
ggatttatagcagcagacaataaagacaatggtacttggactcagctctggttggtgtca
gattatcatgagcatggatccctttttgattacttaaacagatacacagttactgtggaa
ggaatgataaaacttgctctgtccacggcgagcggtcttgcccatcttcacatggagatt
gttggtacccaaggaaagccagccattgctcatagagatttgaaatcaaagaatatcttg
gtaaagaagaatggaacttgctgtattgcagacttaggactggcagtaagacatgattca
gccacagataccattgatattgctccaaaccacagagtgggaacaaaaaggtacatggcc
cctgaagttctcgatgattccataaatatgaaacattttgaatccttcaaacgtgctgac
atctatgcaatgggcttagtattctgggaaattgctcgacgatgttccattggtggaatt
catgaagattaccaactgccttattatgatcttgtaccttctgacccatcagttgaagaa
atgagaaaagttgtttgtgaacagaagttaaggccaaatatcccaaacagatggcagagc
tgtgaagccttgagagtaatggctaaaattatgagagaatgttggtatgccaatggagca
gctaggcttacagcattgcggattaagaaaacattatcgcaactcagtcaacaggaaggc
atcaaaatgtaa

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