KEGG   Pan troglodytes (chimpanzee): 744513
Entry
744513            CDS       T01005                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04010  MAPK signaling pathway
ptr04022  cGMP-PKG signaling pathway
ptr04137  Mitophagy - animal
ptr04141  Protein processing in endoplasmic reticulum
ptr04151  PI3K-Akt signaling pathway
ptr04210  Apoptosis
ptr04211  Longevity regulating pathway
ptr04261  Adrenergic signaling in cardiomyocytes
ptr04668  TNF signaling pathway
ptr04720  Long-term potentiation
ptr04722  Neurotrophin signaling pathway
ptr04725  Cholinergic synapse
ptr04728  Dopaminergic synapse
ptr04911  Insulin secretion
ptr04912  GnRH signaling pathway
ptr04915  Estrogen signaling pathway
ptr04918  Thyroid hormone synthesis
ptr04922  Glucagon signaling pathway
ptr04925  Aldosterone synthesis and secretion
ptr04926  Relaxin signaling pathway
ptr04927  Cortisol synthesis and secretion
ptr04928  Parathyroid hormone synthesis, secretion and action
ptr04932  Non-alcoholic fatty liver disease
ptr04934  Cushing syndrome
ptr04935  Growth hormone synthesis, secretion and action
ptr05010  Alzheimer disease
ptr05012  Parkinson disease
ptr05014  Amyotrophic lateral sclerosis
ptr05020  Prion disease
ptr05022  Pathways of neurodegeneration - multiple diseases
ptr05030  Cocaine addiction
ptr05031  Amphetamine addiction
ptr05034  Alcoholism
ptr05161  Hepatitis B
ptr05163  Human cytomegalovirus infection
ptr05166  Human T-cell leukemia virus 1 infection
ptr05203  Viral carcinogenesis
ptr05207  Chemical carcinogenesis - receptor activation
ptr05215  Prostate cancer
ptr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    744513 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    744513 (ATF4)
   04668 TNF signaling pathway
    744513 (ATF4)
   04022 cGMP-PKG signaling pathway
    744513 (ATF4)
   04151 PI3K-Akt signaling pathway
    744513 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    744513 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    744513 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    744513 (ATF4)
   04922 Glucagon signaling pathway
    744513 (ATF4)
   04912 GnRH signaling pathway
    744513 (ATF4)
   04915 Estrogen signaling pathway
    744513 (ATF4)
   04926 Relaxin signaling pathway
    744513 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    744513 (ATF4)
   04918 Thyroid hormone synthesis
    744513 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    744513 (ATF4)
   04925 Aldosterone synthesis and secretion
    744513 (ATF4)
   04927 Cortisol synthesis and secretion
    744513 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    744513 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    744513 (ATF4)
   04728 Dopaminergic synapse
    744513 (ATF4)
   04720 Long-term potentiation
    744513 (ATF4)
   04722 Neurotrophin signaling pathway
    744513 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    744513 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    744513 (ATF4)
   05203 Viral carcinogenesis
    744513 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    744513 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    744513 (ATF4)
   05161 Hepatitis B
    744513 (ATF4)
   05163 Human cytomegalovirus infection
    744513 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    744513 (ATF4)
   05012 Parkinson disease
    744513 (ATF4)
   05014 Amyotrophic lateral sclerosis
    744513 (ATF4)
   05020 Prion disease
    744513 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    744513 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    744513 (ATF4)
   05031 Amphetamine addiction
    744513 (ATF4)
   05034 Alcoholism
    744513 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    744513 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    744513 (ATF4)
   04934 Cushing syndrome
    744513 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ptr03000]
    744513 (ATF4)
Transcription factors [BR:ptr03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    744513 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF3450 DUF4407 DUF4192 Nop53 AAA_13 Laminin_II bZIP_Maf
Other DBs
NCBI-GeneID: 744513
NCBI-ProteinID: NP_001239446
Ensembl: ENSPTRG00000014398
VGNC: 5227
UniProt: A0A803KHR4 K7BNF9
LinkDB
Position
22:22354959..22357080
AA seq 351 aa
MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
DLFAPLVQETNKEPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSSGVLSSTPDHSFSL
ELGSEVDITEGDRKPDYTGYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgaccgaaatgagcttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaagaaagcctaggtctcttagatgattacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtccctccaacaacagcaaggaggatgccttctcc
gggacagattggatgttggagaaaatggatttgaaggagttcgacttggatgccctgttg
ggtatagatgacctggaaaccatgccagatgaccttctgaccacgttggatgacacttgt
gatctctttgcccccctagtccaggagactaataaggagcccccccagacggtgaaccca
attggccatctcccagaaagtttaacaaaacccgaccaggttgcccccttcaccttcttg
caacctcttcccctttcctcaggggtcctgtcctccactccagatcattcctttagttta
gagctgggcagtgaagtggatatcactgaaggagataggaagccagactacactggttac
gttgccatgatccctcagtgcataaaggaggaagacaccccttcagataatgatagtggc
atctgtatgagcccagagtcctatctggggtctcctcagcacagcccctctaccaggggc
tctccaaataggagcctcccatctccaggtgttctctgtgggtctgcccgccccaaacct
tacgatcctcctggagagaagatggtagcagcaaaagtaaagggtgagaaactggataag
aagctgaaaaaaatggagcaaaacaaaacagcagccactaggtaccgccagaagaagagg
gcggagcaggaggctcttactggtgagtgcaaagagctggaaaagaagaacgaggctcta
aaagagagggcggattccctggccaaggagatccagtacctgaaagatttgatagaagag
gtccgcaaggcaagggggaagaaaagggtcccctag

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