KEGG   Rousettus aegyptiacus (Egyptian rousette): 107499790
Entry
107499790         CDS       T06036                                 

Gene name
KIT
Definition
(RefSeq) mast/stem cell growth factor receptor Kit isoform X1
  KO
K05091  proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04014  Ras signaling pathway
ray04015  Rap1 signaling pathway
ray04072  Phospholipase D signaling pathway
ray04151  PI3K-Akt signaling pathway
ray04640  Hematopoietic cell lineage
ray04916  Melanogenesis
ray05200  Pathways in cancer
ray05221  Acute myeloid leukemia
ray05224  Breast cancer
ray05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107499790 (KIT)
   04014 Ras signaling pathway
    107499790 (KIT)
   04015 Rap1 signaling pathway
    107499790 (KIT)
   04072 Phospholipase D signaling pathway
    107499790 (KIT)
   04151 PI3K-Akt signaling pathway
    107499790 (KIT)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    107499790 (KIT)
  09152 Endocrine system
   04916 Melanogenesis
    107499790 (KIT)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107499790 (KIT)
   05230 Central carbon metabolism in cancer
    107499790 (KIT)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    107499790 (KIT)
   05224 Breast cancer
    107499790 (KIT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ray01001]
    107499790 (KIT)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ray04090]
    107499790 (KIT)
Enzymes [BR:ray01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     107499790 (KIT)
Protein kinases [BR:ray01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   107499790 (KIT)
CD molecules [BR:ray04090]
 Proteins
  107499790 (KIT)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 Ig_6 Ig_4 V-set C1-set APH Pkinase_fungal
Other DBs
NCBI-GeneID: 107499790
NCBI-ProteinID: XP_015979772
LinkDB
Position
Unknown
AA seq 977 aa
MRSARGAWGFLCVLILLLGLQTGSSQPSVSPGELSPPSIHPAESELRVSVGDEIRLLCTD
PRFVKWTFETLGQLTEKSQNEWVMEKAEATSTGNYTCTNEDGLSSSIYVFVSDPAKLFLI
DLPLYGKEGNDTLVRCPLTDPEVTNYSLVGCEGKPLPKDLTFVADPKAGITIRNVRREYH
RLCLHCSADKKDKSVLSKKFSLKVRAAIRAVPVVSVSKASYLLREGEEFTVTCLIKDVSS
SVDSMWIRENSQPTKAQVKRNSWHQGDFNFLRQERLTISSVKVNDSGVFMCYANNTFGSA
NVTTTLEVVDKGFINIFPVANTTIFVNDGANVDLVVEYEAYPKPEHLQWIYMNKTFTDKW
ESYPKSENESNIRYITELHLTRLKGTEGGTYTFLVSNSDVDSSVTFNVYVNIKPEILTHE
RLMNGMLQCVAAGFPEPTIDWYFCPGAEQRCSVPVGPVDVQIQNSSVSPFGKLVVQSSID
YSAFKLNGTVECRAYNDVGKSSAFFNFAFKGNSKEQIHPHTLFTPLLIGFVVAAGMMCII
VMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGA
FGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGA
CTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKVSSCSDSTN
EYMDMKPGVSYVVPTKADKRRSARIGSYIERDMTPAIMEDDELALDLEDLLSFSYQVAKG
MAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPE
SIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPADM
YDVMKTCWDADPVKRPTFKQIVQLIEKQISDSTTHIYSNLANWSPNQESAVVDHSVRINS
VGSSASSTQPLLVHEDV
NT seq 2934 nt   +upstreamnt  +downstreamnt
atgagaagcgctcgcggtgcctggggtttcctctgcgtcctgatcctcctgctcggcctc
cagacaggctcttctcaaccatctgtgagtccaggggaactatctccaccatccatccat
ccagcagaatcagagttaagagtcagtgttggtgatgagattaggctgttatgcactgat
ccaagatttgtcaaatggacttttgagaccttgggtcaattgactgagaaatcacagaat
gaatgggtcatggagaaagcagaggccaccagtacaggcaattacacatgcaccaatgag
gacggcttaagcagttccatttatgtgtttgttagtgatcctgcaaagcttttcctcatt
gaccttcccttgtatgggaaagaaggcaatgatacgctggttcgctgtcctctgactgac
ccagaagtgaccaattactccctcgtgggatgtgaggggaaacctctccccaaggacttg
acgtttgttgctgatcccaaggctggcatcacaatcagaaacgtgaggcgcgagtatcat
cggctctgcttgcactgctctgcggacaagaaggacaagtcagtgctgtcgaagaaattc
tctctgaaagtgagggcagctatcagagctgtaccagttgtgtctgtgtcgaaagcaagc
tatcttcttagggaaggggaagaatttacagtgacgtgcttgataaaagatgtgtctagt
tctgtggactcaatgtggataagggaaaacagccagccaactaaagcacaggtaaagagg
aatagctggcatcagggtgacttcaatttcctacgtcaggagaggttgactatcagctca
gtgaaagttaatgattctggagtattcatgtgttatgccaataatactttcggatcagca
aatgtcacaacaaccttggaagtagtagataaaggattcattaatatcttccctgtggca
aatactacaatatttgtaaatgatggagctaatgtagatctggttgttgaatatgaggca
tacccgaaacctgaacacctacagtggatttatatgaacaaaaccttcactgataagtgg
gagagttatcccaagtctgagaatgaaagtaatatcagatatataactgaacttcaccta
accagattgaaagggacggaaggaggcacgtacacatttctagtgtccaattctgacgtt
gattcttccgtgacatttaacgtttatgtgaacataaaaccagaaatcctgactcatgag
aggctcatgaatggcatgctccagtgtgtggcagcaggattcccagagcccacaatagat
tggtatttttgtccaggagctgagcagagatgttcagttcctgttgggccggtggatgtg
cagatacaaaactcatctgtgtcaccgttcggaaaactagtggttcaaagttccatcgat
tacagtgcattcaagctcaatggcacggtcgagtgtagggcttacaacgatgtgggaaag
agttctgccttttttaactttgcatttaaaggtaacagcaaagaacaaatccatccccac
accttgttcacgcctttgctgattggttttgtggtcgcagctggtatgatgtgcatcatc
gtaatgattcttacatacaaatatttacagaaacccatgtatgaagtacagtggaaggtt
gttgaggagataaatggaaacaattatgtttacatagacccaacacaacttccttatgat
cacaaatgggagtttcccagaaacaggctgagttttgggaaaactttgggtgctggtgcc
ttcgggaaagttgttgaggccactgcgtatggcttaattaaatcagatgcggccatgact
gttgctgtgaagatgcttaaaccaagtgctcatttaacggaaagagaagctctaatgtct
gaactcaaagtcttgagttaccttggtaatcatatgaatattgtgaatcttcttggagca
tgcaccattggagggcctaccctggtcattacagaatattgttgttatggtgatcttttg
aactttctgagaagaaaacgtgattcatttatctgctcaaagcaggaagaccatgcagaa
gcagccctttataagaaccttctgcattcaaaggtgtcttcatgcagtgatagtactaat
gagtacatggacatgaaacctggagtttcttatgttgtaccaaccaaggcagacaaaagg
agatctgcaagaataggctcatacatagaaagagacatgacccctgccattatggaagat
gacgagttggccctggacctggaagacctgctcagcttttcttaccaggtggcaaagggc
atggctttccttgcctcaaagaattgtattcacagagacttggcagccagaaatatcctc
cttactcatggtcgaatcacgaagatttgtgatttcggtctagccagagacatcaagaat
gattctaattacgtggtcaaaggcaatgctcggctacctgtgaaatggatggcacctgaa
agcattttcaactgtgtatacacatttgaaagtgatgtgtggtcctatggtatttttcta
tgggagctgttctccttaggaagcagcccctaccctggaatgccagtggattctaagttc
tacaagatgatcaaggaaggtttccgaatgctgagccctgagcatgcacctgccgacatg
tatgacgtaatgaaaacttgctgggatgccgaccctgtaaaaagaccgacatttaagcag
atcgttcagctgattgagaagcagatttctgacagcaccactcatatttattccaactta
gcaaactggagccccaaccaggagagtgctgtggtggaccattccgtgcggatcaattcc
gtgggcagcagcgcctcgtccacgcagcctctgctcgtacatgaagacgtctga

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