KEGG   Rousettus aegyptiacus (Egyptian rousette): 107499793
Entry
107499793         CDS       T06036                                 

Gene name
PDGFRA
Definition
(RefSeq) platelet-derived growth factor receptor alpha isoform X1
  KO
K04363  platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01521  EGFR tyrosine kinase inhibitor resistance
ray04010  MAPK signaling pathway
ray04014  Ras signaling pathway
ray04015  Rap1 signaling pathway
ray04020  Calcium signaling pathway
ray04072  Phospholipase D signaling pathway
ray04144  Endocytosis
ray04151  PI3K-Akt signaling pathway
ray04510  Focal adhesion
ray04540  Gap junction
ray04630  JAK-STAT signaling pathway
ray04810  Regulation of actin cytoskeleton
ray05163  Human cytomegalovirus infection
ray05200  Pathways in cancer
ray05206  MicroRNAs in cancer
ray05214  Glioma
ray05215  Prostate cancer
ray05218  Melanoma
ray05230  Central carbon metabolism in cancer
ray05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107499793 (PDGFRA)
   04014 Ras signaling pathway
    107499793 (PDGFRA)
   04015 Rap1 signaling pathway
    107499793 (PDGFRA)
   04630 JAK-STAT signaling pathway
    107499793 (PDGFRA)
   04020 Calcium signaling pathway
    107499793 (PDGFRA)
   04072 Phospholipase D signaling pathway
    107499793 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    107499793 (PDGFRA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    107499793 (PDGFRA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    107499793 (PDGFRA)
   04540 Gap junction
    107499793 (PDGFRA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107499793 (PDGFRA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107499793 (PDGFRA)
   05206 MicroRNAs in cancer
    107499793 (PDGFRA)
   05230 Central carbon metabolism in cancer
    107499793 (PDGFRA)
   05231 Choline metabolism in cancer
    107499793 (PDGFRA)
  09162 Cancer: specific types
   05214 Glioma
    107499793 (PDGFRA)
   05218 Melanoma
    107499793 (PDGFRA)
   05215 Prostate cancer
    107499793 (PDGFRA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    107499793 (PDGFRA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    107499793 (PDGFRA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ray01001]
    107499793 (PDGFRA)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ray04090]
    107499793 (PDGFRA)
Enzymes [BR:ray01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     107499793 (PDGFRA)
Protein kinases [BR:ray01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   107499793 (PDGFRA)
CD molecules [BR:ray04090]
 Proteins
  107499793 (PDGFRA)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 I-set ig Ig_2 Herpes_gE C2-set_2 Kinase-like
Other DBs
NCBI-GeneID: 107499793
NCBI-ProteinID: XP_015979779
LinkDB
Position
Unknown
AA seq 1138 aa
MWVWRSRRQEGVSADSPGRRWANRGPGRAVGDPEPELRTRERASQPFSRAMGTSHPAFLV
LGCLLAGPSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPLSDENSNVEI
RNEENNSGLFVAVLEVVNASAAHTGLYTCYYNHTQTEENEIEGRRIYIYVPDPDVAFVPL
GMTDYLVIVEDDDSAIIPCRTTDPDTPVTLLNSDGVVLASYNSRQGFNGTFTVGLYICEA
TVRGRKFRTIPFNVYALKATSELDLEMEAPKTVYKSGETVVVTCAVFNNEVVDLQWTYPG
EMRGKGVTTLEETKVPFIKLVYTLKVPGATVKDSGEYGCAARQATKEVKEMKKVTISVHE
KGFIEIKPNFSQLEAVNLHEVKHFVVDVQAYPPPRISWLKDNLTLIENLTEITTDIEKIQ
EIRYRSKLKLIRAKEEDSGHYTIIVQNEDDVKSYTFELLTQVPSSILDLVDDHHGATGGQ
TVRCTAVGTPLPDIEWMICKDIKKCNNETSWTILANNISNIVTEVHLRDRSTVEGRVTFA
KVEETIAVRCLARNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQ
KPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGT
AYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIY
IITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSYVILSFENNGDY
MDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLT
LLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVS
KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKS
GYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLK
SDHPAVARMRVDADNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPEE
EDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL
NT seq 3417 nt   +upstreamnt  +downstreamnt
atgtgggtgtggcggagcaggaggcaggaaggtgtcagcgcagactctcctgggagaagg
tgggcgaaccgcggtcccggccgcgctgtcggggacccggagcccgagctgcggacgcga
gagcgagccagccagccgttttccagagctatggggacttcccatcctgcattcctggtc
ttaggctgtctccttgcagggccgagcctaatcctctgccagctttcattaccctctatc
ctcccaaacgaaaatgaaaaggttgtgcagctgaattcatccttttctctgagatgcttt
ggggagagcgaagtgagctggcagtaccccttgtctgacgagaactccaacgtggaaatc
agaaatgaggagaataacagtggcctttttgtggccgtgctggaagtggtcaatgcctcg
gcagcccacacggggctgtacacttgctattacaaccacacgcagacagaagaaaatgag
atcgaaggccgacgcatttacatctacgtgccagacccggatgtagcctttgtacctctg
ggaatgacagattatttagtcatcgtggaagacgatgactctgccatcataccttgtcga
acaaccgaccccgatactccagtaaccttactcaacagtgatggggtggtcctcgcctcc
tataacagcagacagggctttaatggaaccttcaccgttgggctctatatctgcgaggcc
accgtcagagggaggaagttccggaccattccatttaatgtttatgctttaaaagcaaca
tcagaacttgatctagaaatggaagcccctaaaactgtatataagtcaggagaaacggtt
gtggtcacctgtgccgtctttaacaacgaggtggttgaccttcagtggacttatcccgga
gaaatgaggggcaaaggtgtcacgacgctggaggaaaccaaggtccccttcatcaagctg
gtgtacacgctgaaggtccctggggccacggtgaaagacagtggagagtatggatgtgcc
gcccgccaggccaccaaggaggtcaaagagatgaagaaagtcaccatttctgtccatgag
aaagggttcattgaaatcaaacccaacttcagccagttggaagctgtcaacctgcatgaa
gtaaaacatttcgtggtggatgtgcaggcctaccctcctcccaggatatcctggctgaaa
gataacctgactctgatcgaaaacctcaccgagatcaccactgacatagaaaagattcag
gaaataaggtatcgaagcaaattaaagctgattcgtgctaaggaagaagacagtggccat
tatactattatagttcaaaatgaagatgatgtgaagagctatacttttgaactcttaact
caagttccctcatctattctggacttggtcgatgatcaccatggtgctacagggggacag
actgtgagatgcacagccgtagggacacctcttcctgatattgaatggatgatttgcaag
gatattaagaaatgtaacaatgagacttcatggacgattttggccaacaacatctcaaac
attgtcacagaggtccacctccgggacaggagcacagtggagggccgggtgacattcgcc
aaagtggaggagactattgcagttcgatgtctggctaggaatcttcttggggctgagaac
cgagagctgaagctggtggctcccactctgcgttctgaacttacagtggcggccgcagtc
ctggtgctcttggtgattgtgatcatctcactgattgtcctggttgtcatttggaaacag
aaaccgaggtatgaaattcgctggagggtcattgaatcaatcagccccgatggacatgaa
tatatttatgtggacccgatgcagctgccttatgactcgagatgggagtttccaagagat
ggactagtgctgggtcgtatcctgggatctggtgcgtttgggaaagtggttgaaggaacc
gcctatggattaagcaggtcccagcctgtcatgaaggtggcagtaaagatgcttaaaccc
acagccagatccagcgaaaaacaagctctcatgtctgaactgaagataatgactcacctg
gggccacatttaaacattgtaaacttgctgggagcctgtaccaagtcgggccccatttac
atcatcactgagtactgtttctatggggatttggtcaactatttgcataagaatagggac
agcttcctgagccgccacccagagaagccaaagaaagagctggacatcttcggattgaac
cccgctgatgaaagcactcggagttatgttattttatcttttgaaaacaatggtgactac
atggacatgaagcaagccgataccacacagtatgtccccatgctggaaaggaaagaggtt
tctaaatattcagacatccagagatctctgtatgatcgcccagcctcatataagaagaaa
tctatgttagattcggaagtcaaaaaccttctttcagacgataactcggaaggccttact
ttgttggatttgttgagctttacctatcaggttgcccgaggaatggaatttttggcttcg
aaaaattgtgtccaccgggacctggccgctcgcaacgtcctcctggcacaagggaaaatt
gtgaagatctgtgactttggcctggccagagatattatgcatgattccaactacgtgtcg
aaaggcagcaccttcctccctgtgaagtggatggctcctgagagcatcttcgacaacctc
tacaccacactgagtgacgtctggtcttacggcattcttctgtgggagatcttttccctt
ggtggtacaccctacccgggcatgatggtggattctactttctacaacaagatcaagagt
gggtaccggatggccaagcctgaccacgccaccagtgaagtctatgagatcatggtgaag
tgctggaacagtgagccggagaagagaccttccttttaccacctgagtgaaattgtggag
aacctgttgcctggacaatataaaaagagttatgaaaagattcacctggacttcctgaag
agtgaccatcccgcagtggcacgcatgcgcgtggatgctgacaatgcttatattggtgtc
acctataaaaatgaagaggacaagctgaaggactgggagggcggccttgatgagcagagg
ctgagtgcagacagcggctatatcatccctctgccggacatcgaccccgtgcctgaggaa
gaagacctgggcaagagaaacagacacagctcacagacctctgaagagagtgctattgag
acgggttccagcagttctaccttcatcaagagagaggatgagaccattgaagacatcgac
atgatggatgacattggtatagactcctcagacctggtggaggacagcttcctgtaa

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