KEGG   Rousettus aegyptiacus (Egyptian rousette): 107500540
Entry
107500540         CDS       T06036                                 

Gene name
CACNA1C
Definition
(RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1C
  KO
K04850  voltage-dependent calcium channel L type alpha-1C
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04020  Calcium signaling pathway
ray04022  cGMP-PKG signaling pathway
ray04024  cAMP signaling pathway
ray04260  Cardiac muscle contraction
ray04261  Adrenergic signaling in cardiomyocytes
ray04270  Vascular smooth muscle contraction
ray04713  Circadian entrainment
ray04720  Long-term potentiation
ray04723  Retrograde endocannabinoid signaling
ray04724  Glutamatergic synapse
ray04725  Cholinergic synapse
ray04726  Serotonergic synapse
ray04727  GABAergic synapse
ray04728  Dopaminergic synapse
ray04742  Taste transduction
ray04911  Insulin secretion
ray04912  GnRH signaling pathway
ray04921  Oxytocin signaling pathway
ray04924  Renin secretion
ray04925  Aldosterone synthesis and secretion
ray04927  Cortisol synthesis and secretion
ray04929  GnRH secretion
ray04930  Type II diabetes mellitus
ray04934  Cushing syndrome
ray04935  Growth hormone synthesis, secretion and action
ray05010  Alzheimer disease
ray05020  Prion disease
ray05022  Pathways of neurodegeneration - multiple diseases
ray05031  Amphetamine addiction
ray05410  Hypertrophic cardiomyopathy
ray05412  Arrhythmogenic right ventricular cardiomyopathy
ray05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107500540 (CACNA1C)
   04020 Calcium signaling pathway
    107500540 (CACNA1C)
   04024 cAMP signaling pathway
    107500540 (CACNA1C)
   04022 cGMP-PKG signaling pathway
    107500540 (CACNA1C)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    107500540 (CACNA1C)
   04929 GnRH secretion
    107500540 (CACNA1C)
   04912 GnRH signaling pathway
    107500540 (CACNA1C)
   04921 Oxytocin signaling pathway
    107500540 (CACNA1C)
   04935 Growth hormone synthesis, secretion and action
    107500540 (CACNA1C)
   04924 Renin secretion
    107500540 (CACNA1C)
   04925 Aldosterone synthesis and secretion
    107500540 (CACNA1C)
   04927 Cortisol synthesis and secretion
    107500540 (CACNA1C)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    107500540 (CACNA1C)
   04261 Adrenergic signaling in cardiomyocytes
    107500540 (CACNA1C)
   04270 Vascular smooth muscle contraction
    107500540 (CACNA1C)
  09156 Nervous system
   04724 Glutamatergic synapse
    107500540 (CACNA1C)
   04727 GABAergic synapse
    107500540 (CACNA1C)
   04725 Cholinergic synapse
    107500540 (CACNA1C)
   04728 Dopaminergic synapse
    107500540 (CACNA1C)
   04726 Serotonergic synapse
    107500540 (CACNA1C)
   04720 Long-term potentiation
    107500540 (CACNA1C)
   04723 Retrograde endocannabinoid signaling
    107500540 (CACNA1C)
  09157 Sensory system
   04742 Taste transduction
    107500540 (CACNA1C)
  09159 Environmental adaptation
   04713 Circadian entrainment
    107500540 (CACNA1C)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107500540 (CACNA1C)
   05020 Prion disease
    107500540 (CACNA1C)
   05022 Pathways of neurodegeneration - multiple diseases
    107500540 (CACNA1C)
  09165 Substance dependence
   05031 Amphetamine addiction
    107500540 (CACNA1C)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    107500540 (CACNA1C)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    107500540 (CACNA1C)
   05414 Dilated cardiomyopathy
    107500540 (CACNA1C)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    107500540 (CACNA1C)
   04934 Cushing syndrome
    107500540 (CACNA1C)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ray04040]
    107500540 (CACNA1C)
Ion channels [BR:ray04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   107500540 (CACNA1C)
SSDB
Motif
Pfam: Ion_trans CAC1F_C GPHH Ca_chan_IQ PKD_channel DUF4834
Other DBs
NCBI-GeneID: 107500540
NCBI-ProteinID: XP_015981380
LinkDB
Position
Unknown
AA seq 2198 aa
MLRAFVQPAMPAYQPLPSHPSAETEVKFKGTLVHEAQLNYFYTPPGGSSYGSPRPAHANM
NANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPK
KQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPED
DSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSA
ILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLH
IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGT
VCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLII
IGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
NEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWN
RFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAE
MLLKVYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKVMSPLGISVLRCVRLLRIFKI
TRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFD
NFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLA
IAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVVEKPAVEETKEEKIELKSIT
ADGESPPTTKINMDDLQPNENEDKSAYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEK
AVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN
HILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA
INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQL
FKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFT
VSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQ
EQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLIL
LNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLI
VIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSR
ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF
GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTE
GETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWA
EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATL
FALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATF
LIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKA
MKEAVSAASEDDIFRRAGGLFGNHVVSYYQSDGRSAFPQTFTAQRPLHINKAGNSQGDTE
SPSHEKLVDSTFTPSSYSSTGSNANINNANNTALARSPRPAGSPSAAGTSEGHGPPSSPA
VRVQEAAWKLNSKRCHSRESQIAMVCQEASQEETYDVKMSDDAEYCSEPSLIATETLSYQ
DDENRQLAPPEEDKRDIRQSPKRGFLRSSSLGRRASFHLECLKRQKNQGGDISQKTVLPL
HLVHHQALAVAGLSPLLQRSHSPTTFRRPCATPPATPGSQGWPPKPIPTLRLEGAESSEN
LNSSFPSIHCSSWAGESTPCGGASSATRKARPVSLTVPSQAGAWGRQFHGSASSLVEAVL
ISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGTQQSPNGTLLPFVNCR
DPGQDRAGVEEDEPCGPPRECRRGEEELQDSRAYVSGL
NT seq 6597 nt   +upstreamnt  +downstreamnt
atgcttcgagcctttgttcagcctgctatgcctgcataccagccgctccccagtcacccg
tctgccgaaacagaggtgaagtttaagggcactttggtgcatgaagctcaactcaactat
ttctacacacctcctggaggttccagctatgggagcccgcgcccagctcatgccaacatg
aatgccaatgcggcggcagggcttgcccccgagcacatccccaccccaggggcggccctg
tcctggcaggcagccatcgatgcggcccggcaggccaagctgatgggaagtgctggcaac
gcgaccatctccactgtcagctccacacagcggaagcggcagcagtacgggaaacccaag
aagcagggcagcacgaccgccacacgcccgcctcgcgccctgctctgcctgactctgaag
aaccccatccgcagggcgtgcataagcattgtcgaatggaaaccatttgaaatcattatt
ttactgactatttttgccaattgtgtggccttagcgatctatattccctttccagaagat
gactccaatgccaccaattccaacctggaacgagtggaatatctctttctcatcattttt
actgtggaagcatttttaaaagtaatagcctacggacttctctttcaccccaatgcttac
ctccgaaacggctggaatttactagattttataattgtggttgtagggctttttagtgca
attttagaacaagcaaccaaagctgacggggccaatgctctaggagggaaaggggctgga
tttgatgtgaaggctctgagggcgttccgcgtgctgcgccccttgcggctggtgtccgga
gtcccgagtctccaggtggtcctgaattccatcatcaaggccatggtccccctgctgcat
atcgccctgctagtgctgtttgtcatcatcatctatgctataatcggcctggagctcttc
atggggaagatgcataagacctgctacaatcaggagggcatagcagatgttccagcagaa
gatgatccttccccttgtgctctggagacgggccacggacgacagtgccagaatggcact
gtgtgcaagcccgggtgggatgggcccaagcacggcatcaccaacttcgacaactttgcc
ttcgccatgttgacagtgttccagtgcatcaccatggagggctggacagacgtgctgtac
tgggtcaatgatgccgtaggaagggactggccctggatctattttgttacacttatcatc
atagggtcattttttgtacttaacttggttctcggtgtccttagcggagagttttctaaa
gagagagagaaggccaaggctcggggagatttccaaaagctgagagagaagcagcagctg
gaagaggatctgaaaggctacttggactggatcacccaggcagaagacatcgaccctgag
aatgaggacgaaggcatggatgaggagaaaccccgaaacatgagcatgcccacaagtgag
acggagtctgtcaacactgagaacgtggctggaggtgacatcgagggagaaaactgtgga
gccaggctggcccaccggatctccaagtcgaagttcagccgctactggcgccggtggaat
cggttctgcagaagaaagtgtcgcgctgcagtcaagtccaatgtcttctattggctcgtg
atcttcctggtgttcctcaacacgctcaccatcgcctcggagcattacaaccagcctcac
tggctcacagaagtccaagacacagccaacaaggcactactggcccttttcacggcagag
atgctgctgaaggtgtacagcctgggattgcaggcctacttcgtgtccctgttcaaccgc
tttgactgcttcgtggtgtgcgggggcatcctggagaccatcctggtggagaccaaggtc
atgtcccccctgggcatctccgtgctcagatgcgtccggctactgaggatatttaaaatc
acaaggtactggaactccttaagcaacctggtggcatccttgctgaactccgtgcgctcc
atcgcctccctgctgctgcttctcttcctgttcatcatcatcttctccctcctgggaatg
cagctctttggaggaaagttcaactttgatgagatgcagacccggaggagtacatttgat
aactttccccagtccctcctcactgtgtttcagatcctgaccggggaggactggaattcg
gtgatgtatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgt
atttacttcatcatcctcttcatctgtggaaactatatcctactgaatgtgttcttggcc
attgccgtggacaacctggctgatgctgagagcctcacatctgcccaaaaggaggaagaa
gaagagaaggagaggaagaagctggccaggactgccagcccagaaaagaaacaagaggtt
gtggagaagccagcagtggaggagaccaaggaggagaaaatagagctgaaatccattaca
gccgatggagagtccccacccaccaccaagatcaacatggatgacctccagcccaatgaa
aatgaggataagagtgcctaccccaacccagaaactacaggagaagaggatgaggaggag
cccgagatgcctgtgggcccccgcccacgaccgctgtctgagctgcaccttaaggaaaaa
gcagtgcccatgccagaagccagtgcgtttttcatcttcagccccaacaacaggttccgc
ctccagtgccaccgcattgtcaatgacacgatcttcaccaacttgatcctcttcttcatt
ctgctcagcagcatctccctggcggctgaggaccctgtgcagcacacgtccttcaggaac
catattctattttattttgatattgtttttactaccattttcaccattgaaattgctctg
aagatgactgcttatggggctttcttgcacaagggctccttttgccggaactacttcaac
atcttggatctgctggtggtcagcgtgtccctcatctcctttggcatccagtccagtgcc
atcaatgtggtaaagatcttgcgagttctgagagtactcaggcccctgagggccatcaac
agagccaagggactgaagcacgtggttcagtgtgtgttcgtcgccatccggacgatcggg
aacatcgtgattgtcaccacactgcttcagttcatgttcgcctgcatcggggtccaactc
ttcaagggaaagctctacacctgttcagacagttccaagcagacagaggcagaatgcaag
ggtaactacatcacgtacaaggacggggaggtcgaccaccccatcatccagccccgcagc
tgggagaacagcaagttcgacttcgacaatgttctggcagctatgatggccctcttcact
gtctccacctttgaggggtggccagagctgctgtaccgctccatcgactcccacacggag
gacaagggccccatctacaactaccgcgtggagatctccatcttcttcatcatctacatc
atcatcatcgccttcttcatgatgaacatcttcgtgggtttcgtcatcgtcaccttccag
gagcagggcgagcaggagtacaagaactgtgagctggacaagaaccagcgacagtgtgtg
gaatacgccctcaaggcccggcccctgcggaggtacatacccaagaaccagcaccagtac
aaagtgtggtatgtggtcaactccacctactttgagtacctgatgttcgtcctcatcctg
ctcaacaccatctgcttggccatgcagcactacggtcagagctgcctgttcaaaatcgcc
atgaacatcctcaacatgctcttcactggcctcttcactgtggagatgattctgaagctc
attgccttcaaacccaagggttactttagtgatccctggaatgtttttgacttcctcatc
gtaattggcagcataattgacgtcattctcagtgaaactaatcactatttctgtgatgca
tggaatacatttgacgccttgattgttgtgggtagcattgttgatatagcaatcaccgag
gtaaacccagctgaacacacccaatgctctccctttatgaacgcagaggagaactcccgc
atctccatcaccttcttccgcctcttccgggtcatgcgcctggtcaagctgctgagccgc
ggggagggcatccggaccttgctgtggaccttcatcaagtccttccaggccctgccctac
gtggccctgctgatagtgatgctcttcttcatttacgccgtgattgggatgcaggtgttt
gggaaaattgccctgaacgacaccacagagatcaaccggaataacaactttcagaccttc
ccccaagctgtgctgctcctcttcaggtgtgccaccggggaggcgtggcaggacatcatg
ctggcctgcatgccagggaagaagtgcgccccagagtcggagcccagcaacagcacagaa
ggggagacaccctgtggcagcagcttcgccgtcttctacttcatcagcttctacatgctc
tgtgccttcctgatcatcaacctcttcgtagctgtcatcatggacaactttgactacctg
acaagggattggtcaatccttggtccccaccatctggatgaatttaaaagaatctgggca
gagtatgaccctgaagccaagggtcgtatcaaacacctagacgtggtgaccctgctccgg
cggattcagcccccattgggttttgggaagctgtgccctcaccgcgtggcttgcaaacgc
ctggtctccatgaatatgcctctgaacagcgatgggacagtcatgttcaatgccaccctg
tttgccctggtccggacagccctaaggatcaaaacagaagggaacctggaacaagccaac
gaggagttgcgggccataatcaagaagatctggaagcggaccagcatgaagctgctggac
caggtggtgccccccgcaggcgatgatgaggtcacggttggcaagttttatgctactttc
ctgatccaagagtacttccggaaattcaagaagcgcaaagaacagggcctcgtgggcaag
ccgtcccagaggaatgccttgtccctgcaggctggcttgcgcactctacatgacatcggg
cccgagatccgacgagccatctctggagacctgacagctgaggaggagctggacaaagcc
atgaaggaggctgtgtctgctgcctccgaagatgacatcttcaggagggccggtggcctg
tttggcaaccacgtcgtcagctactaccaaagcgacggccggagcgccttcccccagacc
ttcaccgcccagcgcccgctgcacatcaacaaggcagggaacagccaaggtgacaccgaa
tctccatcccacgagaaactggtggactccaccttcacccccagcagctactcatccact
ggctccaacgccaacatcaacaacgccaacaacaccgccctggcccgctccccgcgcccc
gccggctcccccagcgcggccggaacctcggagggccacgggcccccctcgtctcctgct
gtccgggtgcaggaggcagcgtggaagctcaactccaagaggtgccactcccgggagagc
cagatagccatggtgtgtcaggaggcctcccaggaagagacctacgacgtgaagatgagt
gatgatgccgagtactgcagtgagcccagcctgatcgccacagagacgctctcctatcag
gatgatgaaaaccgacaactagcaccccctgaggaggacaagagggacatccggcaatct
ccaaagaggggtttcctccgctcatcctccctaggtcgaagggcctccttccacctggaa
tgtctgaagcgacagaagaatcaagggggagacatctctcagaagacagttctgcccttg
catctggtccatcatcaggcattggccgtggcaggcctgagcccactcctccagagaagc
cattcccccaccacgttccgcagaccatgtgccacccctccagccacgcccggcagccaa
ggctggcccccaaagcccatccccaccctgcggctggaaggagccgagtccagtgagaat
ctcaacagcagcttcccatccatccactgcagctcctgggctggggagtccacgccctgt
gggggggccagcagtgccacccggaaagcccggcctgtgtccctcacggtgcccagccag
gccggggcctggggcaggcagttccatggcagcgccagcagtctggtggaagcggtcttg
atttcagaaggactggggcagtttgctcaagatcccaaattcatcgaagtcacaacccag
gagctggctgatgcctgcgacatgaccatagaggagatggagaatgctgctgacaacatc
ctcagtgggggcacccagcagagccccaacggcaccctattaccttttgttaactgcagg
gacccggggcaggacagggcaggggtggaagaggacgagccctgcgggcccccgcgggag
tgccgaaggggcgaggaggagctgcaggacagccgagcctacgtcagcggcctgtag

KEGG   Rousettus aegyptiacus (Egyptian rousette): 107505355
Entry
107505355         CDS       T06036                                 

Gene name
CACNA1B
Definition
(RefSeq) LOW QUALITY PROTEIN: voltage-dependent N-type calcium channel subunit alpha-1B
  KO
K04849  voltage-dependent calcium channel N type alpha-1B
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04020  Calcium signaling pathway
ray04721  Synaptic vesicle cycle
ray04723  Retrograde endocannabinoid signaling
ray04725  Cholinergic synapse
ray04726  Serotonergic synapse
ray04727  GABAergic synapse
ray04728  Dopaminergic synapse
ray04930  Type II diabetes mellitus
ray05016  Huntington disease
ray05020  Prion disease
ray05022  Pathways of neurodegeneration - multiple diseases
ray05032  Morphine addiction
ray05033  Nicotine addiction
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107505355 (CACNA1B)
   04020 Calcium signaling pathway
    107505355 (CACNA1B)
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    107505355 (CACNA1B)
   04725 Cholinergic synapse
    107505355 (CACNA1B)
   04728 Dopaminergic synapse
    107505355 (CACNA1B)
   04726 Serotonergic synapse
    107505355 (CACNA1B)
   04723 Retrograde endocannabinoid signaling
    107505355 (CACNA1B)
   04721 Synaptic vesicle cycle
    107505355 (CACNA1B)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    107505355 (CACNA1B)
   05020 Prion disease
    107505355 (CACNA1B)
   05022 Pathways of neurodegeneration - multiple diseases
    107505355 (CACNA1B)
  09165 Substance dependence
   05032 Morphine addiction
    107505355 (CACNA1B)
   05033 Nicotine addiction
    107505355 (CACNA1B)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    107505355 (CACNA1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ray04040]
    107505355 (CACNA1B)
Ion channels [BR:ray04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   107505355 (CACNA1B)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 107505355
NCBI-ProteinID: XP_015990941
LinkDB
Position
Unknown
AA seq 2325 aa
MVRFGDELGGRYGAPXGGERARGGGAGGAGGPGPGGXQPGQRVLYKQSIAQRARTMALYN
PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
GDKTPMSERLDDTEPYFIGVFCFEAGIKIVALGFALHKGSYLRNGWNVMDFVVVLTGILA
TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
GLEFYMGKFHKACFPNSTDADPTGDFPCGPEPPARVCEGDTECREYWPGPNFGITNFDNI
LFSVLTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
TKKSRNDLIHAEEGEDRFADLCAGGSPFARAGLKSGKTESSSYFRRKEKMLRFLVRRVVK
AQSFYWAVLCVVALNTLCVAMVHHNQPQRLTTALYFAEFVFLGLFLTEMSLKMYGLGPRS
YFRSSFNCFDFGVIVGSIFEVVWAAIKPGTSFGISVLRALRLLRIFKVTKYWNSLRNLVV
SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFKDETPTTNFDTFPAAILTVFQIL
TGEDWNAVMYHGIESQGGVSKGMFSSCYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
DEEEMEEAANQKLALQKAKEVAEVSPVSAANVSVAARQQSSAKARSVWEQRASQLRLQNL
RASCEALYSELDPEERLRYATTRHLRPDMKTHLDRPLVVEPSRNGPRGPAAGKAQPEGAE
ATEGTDPPRRHHRHRDKDKAPAPAAGEPERADAPKAEGGEPVAREERVRGRTAAATAFRG
PGPEGGATTRHGSPEEVAEREPRRHRTHRHAPDQGKEGSAPGAKGERRARHRGGTRAGAR
EPESMEEPARRHRARHRAPPTHEDAEKEAEEKEXARPKDRDRDKEVRNHQPKEPRGDLGD
GGVTAVGPVHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPADPGAPVHIPAAPTGPPAEG
TVVPSGSGDLESQADGRKAAEAEDVTRSGPRPIVPYSSMFCLSPTALLRRCCHYIVTMRY
FEMVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMIDLGLLLHP
GAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAV
FDCVVNSLRNVLNILVVYVLFMFIFAVIAVQLFKGKFFYCTDESKERERDCRGQYLDYEK
EEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRME
LSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISARPLTR
YMPRDKQSLQYKTWTFVVSPPFEYFIMAMIALNTLVLMMKFYGAPYEYELLLKGLNVAFT
SVFSMECLLKIVAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFR
AARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDSS
INRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSDRACDEHASASACGSDFAYFYFVSF
IFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYSDMFE
MLKHMSPPLGLGKKCPARVAYKRLVRMNMPISSEDMTVHFTSTLMALIRTALEIKLAPAG
TTQHQCDAELRKEISSVWANLPQKTLDLLVPPHKPDEVTVGKVYAALMIFDFYKQSKSSR
DQTHQAPGGLTQMGPVSLFHPLKATLEQTQPAVLRGARVFLQQKSSTSLSNGGAVQTQES
GIKESVSWGTQRTQDMLCESRRPLERGHSTEIPVVHPGKPAADVQTQSMALRGPDGEPQP
GLESQGRAASMPRLAAETQPAPGASPMKRSVSTLAPQRPRAAPLCNAAPDRAPAGPAAAH
HHHRCHRRRDRKQKSLEKGPSLSADTDGAPHSAGPGPPPAEGPAGGRRERRQERGRSQER
RQPSSSSSEKQRFYSCDRFGGREPPHPRPSLSSHPTSPTAGQEPGPLRQGGGSANGSPLL
SASGASTPGRGGRRQLPQTPLTPRPSVTYKTAHSSPVHFAGAQTSLPAFSPGRLSRGLSE
HNALLQRDPLSQPLAPSSRTGSDPYLGQRLDGETTARTQPEDALTFEEAVATNSGRSSRT
SYVSSLTSQPHPPRRVPNGYHCTLGPGPGSRARLSAHHPDRDHWC
NT seq 6978 nt   +upstreamnt  +downstreamnt
atggtccgcttcggagacgagctgggcggccgctatggggcgccgngcggcggggagcgg
gcccggggcggcggggctggcggggccggcggcccgggcccggggggcntgcagccgggc
cagcgggtcctctacaagcagtcgatcgcgcagcgcgcgcgcaccatggcgctgtacaac
cccatcccggtcaagcagaactgcttcaccgtcaaccgctcgcttttcgtcttcagcgag
gacaacgtcgtccgcaaatacgccaagcgcatcacggagtggcctccgtttgagtacatg
atcctggccaccatcatcgccaactgtatcgtgctggcactggagcagcacctccctgac
ggcgacaagacgcccatgtccgagcggctggacgacacggagccctacttcatcggcgtc
ttctgcttcgaggcgggcatcaagatcgtcgccctgggcttcgcgctgcacaagggctcc
tacctacgcaatggctggaacgtcatggacttcgtggtggtcctcacggggatcctggcc
acagctggcactgacttcgacctgcgaacgctacgtgctgtgcgcgtgctgaggcccctg
aagctggtgtccgggatccccagtttgcaggtggtgctcaagtccatcatgaaggccatg
gtcccactcctgcagattgggctgctcctcttctttgccatcctcatgttcgccatcatt
ggcctggagttctacatgggcaaattccacaaggcctgtttccccaacagcacagatgca
gatcccactggtgacttcccctgtggcccagagccccctgcccgggtgtgtgagggcgac
accgagtgccgggagtactggccagggcccaacttcgggatcaccaacttcgacaacatc
ctgttctccgtcctgacggtgttccagtgcatcaccatggagggctggactgacatcctc
tacaatacaaacgacgcggccggcaacacgtggaactggctctacttcatccctctcatc
atcatcggctccttcttcatgcttaacctggtgctgggcgtgctctctggcgagtttgcc
aaggagcgcgagcgggtggagaaccggcgggccttcctgaagctgcgccggcagcagcag
atcgagcgggagctcaacggatacctggagtggatcttcaaggccgaggaagtcatgctg
gctgaggaggacaggaatgcagaggagaagtcccctctggatgtgctgaagagagcagcc
accaagaagagccggaacgacctgatccacgcagaggagggcgaggaccgcttcgcagac
ctctgtgccggggggtcccccttcgcccgcgccggcctcaagagtgggaagacggagagc
tcgtcgtacttccgccggaaggagaagatgctgcggttcctggtgcggcgagtggtgaag
gcgcagagcttctactgggcagtgctgtgcgtggtggcgctgaacacgctgtgcgtggcc
atggtgcaccacaaccagccccagcggctcaccacggcgctgtactttgcagagtttgtt
ttcctgggtctcttcctcacagagatgtccctgaagatgtatggcctggggccccggagc
tacttccggtcctccttcaattgcttcgacttcggggtcatcgtggggagcatcttcgaa
gtggtgtgggctgccatcaagccaggaacctcctttgggatcagtgttctgcgggcactc
cggttgctgaggatcttcaaagtcacaaagtactggaactccctgcggaacctggtggtg
tccctgctcaactccatgaagtccatcatcagcctgctcttcttgctcttcctcttcatc
gtggtcttcgccctgctgggcatgcagctgttcgggggacagttcaactttaaagatgag
acgccaaccaccaactttgacaccttccctgccgccatcctcactgtgttccagatcctg
accggggaggactggaatgctgtgatgtaccacgggatcgagtcgcagggtggagtcagc
aaaggcatgttctcgtcctgctatttcatcgtcctgacgctgttcgggaactacaccttg
ctgaatgtcttcctggccatcgccgtggacaacctcgccaacgcccaggagctgaccaag
gatgaagaggagatggaggaggcggccaaccagaagctcgccctgcagaaggccaaggag
gtggctgaagtcagccctgtgtcggccgccaacgtctccgtcgctgccaggcagcagagc
tcggccaaggcgcgctcggtgtgggagcagcgggccagccagctgcggctgcagaacctg
cgggccagctgcgaggcgctgtacagcgagctggaccccgaggagcggctgcgctacgcc
accacgcgccacctgcggcccgacatgaagacgcacctggaccggccgctggtggtggag
cccagcaggaatggcccgcgggggccggccgcaggcaaggcccagcccgagggcgcggag
gccaccgagggcacggacccgccacgcaggcaccaccggcaccgcgacaaggacaaggcc
ccggccccggctgccggggagcccgagcgggcggacgccccaaaggcggagggcggggag
ccggtggcccgggaagagcgagtgcgcggccgcaccgcagccgcaacggcattccgcggc
ccggggcctgagggcggcgccaccacccggcacgggtccccggaggaggtggccgaacgg
gagccccggcgccaccgcacccaccggcacgcgcccgaccagggcaaagagggcagcgca
cctggggccaagggcgagcggcgggcacggcaccgcggcggcacccgggccggtgcccgg
gagcccgagagcatggaggagccggcacggcggcaccgggcacggcacagggcgccaccc
acacacgaggacgcggagaaggaggcagaggagaaggagnnggcgagacccaaggacagg
gacagggacaaggaagtccggaaccaccagcccaaggagccacgtggggacctgggggac
ggcggggtgacggctgtgggccctgtgcacacgctgcccagcacctgtctacagaaggtg
gaggagcagccggaggacgcggataaccagcggaacgtcactcggatgggcagccagccc
gcagaccccggtgcccctgtgcacatcccggcggcgccgaccgggccccccgccgagggc
accgttgtccccagtggcagcggggacctggaaagccaagcagatgggaggaaggcggcg
gaggccgaggacgtgacgaggagcggcccccggcccatcgtcccctacagctccatgttc
tgcctgagccccactgccctgctccgccgttgctgccactacatcgtgaccatgaggtac
ttcgagatggtcatccttgtggtcatcgccctgagcagcatcgctctggccgcagaggac
cccgtgcggacagactcgcccaggaacaacgccctgaaatacttggactacatcttcacg
ggcgtcttcacctttgagatggtgatcaagatgattgatctggggctgctgctgcatccc
ggggcctacttccgggacctgtggaatattctggacttcattgtggtcagtggggccctg
gtggcgtttgccttctcgggctccaaagggaaagacatcaacaccatcaagtccctgagg
gtcctgcgtgtcctgcggccgctcaagaccatcaagcggctgcccaagctcaaggccgtg
ttcgactgcgtggtgaactccctgcgcaacgtgctcaacatcctggtcgtctacgtgctc
ttcatgttcatcttcgccgtcatcgccgtgcagctgttcaagggcaagttcttctactgc
acggacgagtccaaggagcgggagcgggactgccggggccagtatctggactacgagaag
gaggaagtggaggcccagcctcggcagtggaagaagtacgacttccactacgacaacgtg
ctctgggcactgctgacgctcttcaccgtgtccactggcgaagggtggcccatggtgctg
aaacactccgtggatgccacctacgaggagcagggcccaagccctgggtaccgcatggag
ctgtccatcttctacgtggtctacttcgtggtctttcccttcttctttgtcaacatcttc
gtggccttgatcatcatcaccttccaggagcagggggacaaggtgatgtcagaatgtagc
ctggagaaaaacgagagggcttgcatcgacttcgccatcagcgccagacccctgacgcgg
tacatgccacgggacaagcagtcgctgcagtacaagacgtggacgttcgtggtgtctcca
cccttcgagtacttcatcatggccatgatagccctcaacacgctggtgctgatgatgaag
ttctacggcgcgccctatgagtacgagctgctgctgaagggcctgaacgtggccttcacc
tccgtgttctccatggagtgcctgctgaagatcgtcgcgttcggggtgctgaactacttc
agagatgcttggaatgtgtttgactttgtcactgtgctgggaagtattactgatatttta
gtgacagaaattgcggaaacgaacaacttcatcaacctgagcttcctgcgcctgttccgc
gcggcgcggctcatcaagctgctgcgccagggctacaccatccgcatcctgctgtggacc
ttcgtgcagtccttcaaggccctgccctacgtgtgcctgctcatcgccatgctcttcttc
atctacgccatcatcggcatgcaggtgttcgggaacatcgccctggacgatgactccagc
atcaacagacacaacaacttccggacgtttctacaggccttgatgctgctgttcaggagc
gccacaggggaggcctggcacgagatcatgctgtcctgcctcagcgaccgggcctgcgac
gagcatgccagcgccagcgcctgcggcagcgacttcgcctacttctacttcgtgtccttc
atcttcctgtgctccttcctgatgctgaacctcttcgtggctgtgatcatggacaacttc
gagtacctcacacgggactcgtccatcctggggccgcaccacctggacgagttcatccga
gtgtgggccgagtacgacccggccgcgtgcgggcgcatcagttacagtgacatgtttgag
atgctgaagcacatgtccccgcccctggggctggggaagaagtgcccggcccgagttgcc
tacaagcgcctggtccgcatgaacatgcccatctccagtgaggacatgaccgtccacttc
acgtccacactgatggccctcatccggaccgcgctagagatcaagctggctccagccggc
accacgcagcaccagtgcgacgcagagctgaggaaggagatctcctccgtgtgggccaac
cttccccagaagactctggatttgctggtgccaccccataaacccgacgaggtgacggtg
gggaaagtctacgccgccctgatgatcttcgacttctacaaacagagcaaaagcagcagg
gaccagactcaccaagccccgggaggcctgacccagatgggtcccgtgtccctgtttcac
cctctgaaggccacgctggagcagacacagccggctgtgctccgaggggcccgggttttc
cttcagcagaagagctcgacctctctcagcaatggcggggcggtacaaacccaagagagt
ggcatcaaggagtctgtttcctggggcacccaaaggacccaggacatgctctgtgagtca
aggaggcccctagagcgtggccactcgacagagatcccagtggtgcatcccggaaaacca
gctgcggatgtccagacgcagagcatggccctgaggggccctgacggggagccccagcct
gggctggagagccagggccgtgcggcctccatgccccgcctggcagcagagacacagccg
gcccccggcgccagccccatgaagcgctcggtgtccacgctggcgccgcagcgcccccgc
gcggccccgctgtgcaacgccgccccggaccgcgcccccgccggcccggccgccgcgcac
caccaccaccgctgccaccgccgcagggacaggaagcagaagtccctggagaaggggccc
agcctgtccgcggacacggatggcgccccccacagcgcggggccggggccgcccccggcg
gaggggcccgcaggcggccggcgggagcgcaggcaggagcgcggccggtcccaggagcgc
aggcagccgtcgtcgtcgtcctccgagaagcagcgcttctactcgtgcgaccgcttcggg
ggccgcgagcccccgcacccccggccctccctcagcagccaccccacctcgcccacggcc
gggcaggagccaggacccctgaggcagggtggcggctcggcaaacgggagccccttgctg
tcagcatccggtgctagcacccctggccgtggcgggcggaggcagctcccccagacccca
ttgacgccccggcccagcgtcacctacaagacagcgcactcctcgcctgtgcacttcgcg
ggggctcagaccagcctcccggccttctcccccggccggctgagccgaggcctttccgaa
cacaacgccttgctccagagagaccccctcagccagcccctggcccccagctctcggact
ggctctgacccttacctggggcagcgtcttgacggtgagaccacggcccgcacccagccc
gaggacgcactcaccttcgaggaggccgtggccaccaactccggccgctcctcccggact
tcctacgtgtcctccctgacttcgcagccccatcccccccgccgcgtgcccaacgggtac
cactgcaccctgggcccgggccccggcagccgagcacgtctcagtgcccaccaccccgac
cgggaccactggtgctag

KEGG   Rousettus aegyptiacus (Egyptian rousette): 107513628
Entry
107513628         CDS       T06036                                 

Gene name
CACNA1S
Definition
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04020  Calcium signaling pathway
ray04022  cGMP-PKG signaling pathway
ray04024  cAMP signaling pathway
ray04260  Cardiac muscle contraction
ray04261  Adrenergic signaling in cardiomyocytes
ray04270  Vascular smooth muscle contraction
ray04723  Retrograde endocannabinoid signaling
ray04725  Cholinergic synapse
ray04726  Serotonergic synapse
ray04727  GABAergic synapse
ray04911  Insulin secretion
ray04912  GnRH signaling pathway
ray04921  Oxytocin signaling pathway
ray04924  Renin secretion
ray04925  Aldosterone synthesis and secretion
ray04927  Cortisol synthesis and secretion
ray04929  GnRH secretion
ray04934  Cushing syndrome
ray04935  Growth hormone synthesis, secretion and action
ray05010  Alzheimer disease
ray05020  Prion disease
ray05022  Pathways of neurodegeneration - multiple diseases
ray05410  Hypertrophic cardiomyopathy
ray05412  Arrhythmogenic right ventricular cardiomyopathy
ray05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107513628 (CACNA1S)
   04020 Calcium signaling pathway
    107513628 (CACNA1S)
   04024 cAMP signaling pathway
    107513628 (CACNA1S)
   04022 cGMP-PKG signaling pathway
    107513628 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    107513628 (CACNA1S)
   04929 GnRH secretion
    107513628 (CACNA1S)
   04912 GnRH signaling pathway
    107513628 (CACNA1S)
   04921 Oxytocin signaling pathway
    107513628 (CACNA1S)
   04935 Growth hormone synthesis, secretion and action
    107513628 (CACNA1S)
   04924 Renin secretion
    107513628 (CACNA1S)
   04925 Aldosterone synthesis and secretion
    107513628 (CACNA1S)
   04927 Cortisol synthesis and secretion
    107513628 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    107513628 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    107513628 (CACNA1S)
   04270 Vascular smooth muscle contraction
    107513628 (CACNA1S)
  09156 Nervous system
   04727 GABAergic synapse
    107513628 (CACNA1S)
   04725 Cholinergic synapse
    107513628 (CACNA1S)
   04726 Serotonergic synapse
    107513628 (CACNA1S)
   04723 Retrograde endocannabinoid signaling
    107513628 (CACNA1S)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107513628 (CACNA1S)
   05020 Prion disease
    107513628 (CACNA1S)
   05022 Pathways of neurodegeneration - multiple diseases
    107513628 (CACNA1S)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    107513628 (CACNA1S)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    107513628 (CACNA1S)
   05414 Dilated cardiomyopathy
    107513628 (CACNA1S)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107513628 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ray04040]
    107513628 (CACNA1S)
Ion channels [BR:ray04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   107513628 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans GPHH Ca_chan_IQ PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 107513628
NCBI-ProteinID: XP_016006031
LinkDB
Position
Unknown
AA seq 1933 aa
MEPPSPQDEGLRRKQPKKPVPEVLPRPPRALLCLTLQNPLRKACISIVEWKPFETIILLT
IFANCVALAVYVPMPEDDNNTLNVGLEKLEYVFLTVFSLEAAVKIIAYGFLFHQDAYLRS
GWNAMDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVTIYAIIGLELFKGKMHKTCYFTGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLD
EDLRGYMSWITQGEVMDDEDLREGKLSLDEGASDTESLFEIEGLDKVIQFVRHWRHWNRI
LRWKCREVLKSRAFYWLVILIVALNTLSIASEHHAQPLWLTHLQDVANQVLLSLFTVEML
MKMYGLGLRQYFMSLFNRFDCFVVCSGLLELLLVGTGAMSPLGISVLRCIRLLRIFKVTK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDSAVPRSNFDSF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKRGLPDKPEEDKSVVAKKLEQKPKGEGIPTTAKLKI
DEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIF
SPTNKWVAPGSVLCHRIVNATWFTNFILLFIMLSSAALAAEDPIRAESMRNQILGHFDIA
FTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLKSSSISVVKILRV
LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTALLQFMFACIGVQLFKGKFFRCN
DLSKMTEEECRGHYYVYEDGDPARVGVQPRRWLHSDFHFDNVLSAMMSLFTVSTFEGWPQ
LLYEAIDSHEEDKGPVYNNRVEVAIFFLIYIILVAFFMMNIFVGFVIVTFQEQGETEYKN
CELDKNQRQCVQYALKARPLKCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTVCLGMQ
HYNQSEQMNHISDILNVAFTIIFTLEMVLKLVAFKARGYFGDPWNVFDFLIVVGSIIDVI
LSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLW
TFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFR
CATGEAWQEILLACSSGKLCDPESEFAPGEEHSCGTGFAYYYFVSFYMLCAFLIINLFVA
VIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKF
CPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALRIKTEGNFEQANEELRAIIKKIW
KRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAG
LRTIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGAVDNFLERTNSL
APAMASQRPLQFAEIEMEELESPVFLEDFPQDPRVSPLARANANNANNANAAGGNGSPGG
RRGCSSIRYVRECPGESATPAAGGGAQGQCPPGGLGTGPSPQLGAGLGGLAWGLAWGPVA
AGTSRGRVGSWPVQPLIQAEEQGALQVMGGTGPQDASSRGSWLRLLGRVGYPGPSASSFP
GVSASVHLQQRPRAEPPTPGSLPEDAPRSGWPHKRPSKCPAPSTALLIQEALVRGGLETL
AADAGFVTATGQALADACRMEPEDVEVAATELLRGRGSPVGTAGAQGGLSLRSSLGSLDQ
CQGSQETLIPPGL
NT seq 5802 nt   +upstreamnt  +downstreamnt
atggagccgccctccccacaggacgagggcctgcggaggaagcaacccaagaagccggtc
cccgaggtcctgccgaggccgccccgggccttgctgtgcctgaccctgcagaacccgctg
aggaaggcatgcatcagcatcgtggagtggaaacccttcgagaccatcatcctgctcacc
atctttgccaactgcgtggccctggccgtgtatgtgcccatgccggaggatgacaacaac
acgctcaacgtcggcctggagaagctggagtacgtcttcctcaccgtcttctccctggag
gcggccgtgaagatcatcgcctatggcttcctcttccaccaggacgcctacctgcgcagc
ggctggaatgccatggacttcatcatcgtcttcctgggggtcttcaccgtgatcctggag
caagtcaacgtcatccagagcaacacggcgcccatgagcagcaagggcgccggcctggac
gtgaaggccctcagggccttccgtgtgctccgacccctgcggctggtgtcgggggtgccc
agcctgcaagtggtcctcaactccatcttcaaggccatgctgcccctgttccacatcgcg
ctgctggtcctcttcatggtcaccatctacgccatcatcggcctggagctgttcaagggc
aagatgcacaagacctgctacttcacggggaccgacatcgtggccacggtggagaacgag
aagccgtcgccctgcgcccggacgggctccggccggccgtgcaccatcaacggcagcgag
tgccggggcggctggccggggcccaaccacggcatcacccacttcgacaacttcggcttc
tccatgctgacggtgtaccagtgcatcaccatggagggctggaccgacgtcctttactgg
gtcaacgatgccattgggaacgagtggccatggatctactttgtcaccctcattctgctg
ggctccttctttatcctcaacctggtgctgggtgtcctgagcggggagtttaccaaggaa
cgggagaaggccaagtccaggggaacgttccagaagctccgggagaagcagcagctagac
gaggacctccggggctacatgagctggatcacgcagggcgaggtcatggacgacgaggac
ttgcgagaaggaaagctgtctctggacgaaggtgcttctgacacggagagcctttttgag
attgagggtttggacaaagtcatccagttcgtccggcactggagacactggaaccgcatc
cttcgctggaaatgccgcgaggtgctgaagtcgcgggccttctactggctggtgatcctg
atcgtggccctcaacaccctgtccatcgcctccgagcaccacgcccagcctctctggctg
acccacctgcaagacgtagccaaccaggtgctgctgtccctgttcaccgtggagatgctg
atgaagatgtacggcctgggcctgcgccagtacttcatgtccctgttcaaccgcttcgac
tgcttcgtggtgtgcagcggcctgctggagctgctgctcgtgggcacgggcgccatgagc
ccgctgggcatctcggtgctgcgctgcatccgcctgctcaggatcttcaaggtcaccaag
tactggacgtcgctgagcaacctggtggcgtcgctgctcaactccatccgctccatcgcc
tcgctgctgctgctgctcttcctcttcatcgtcatcttcgcgctgctgggcatgcagctc
ttcggcggcaggtacgacttcgaggactccgcggtgccccgcagcaacttcgacagcttc
ccgcaggccctcatcagcgtcttccaggtcctgacgggcgaggactggaactcggtgatg
tacaacgggatcatggcgtacggcgggccctcctaccccggcatgctcgtgtgcatttac
ttcatcatccttttcgtctgcggcaactacatcctgctcaatgtcttcctggccatcgca
gtggacaacctggccgaggcagagagcctgacgtctgcccagaaggccaaggccgaggag
agaaagcgcaggaagagggggctcccggacaagcctgaggaggacaagtcggtggtggcc
aagaagctggaacagaagcccaagggagagggcatccccaccacggccaagctgaaaatc
gacgagtttgagtcgaacgtcaacgaggtgaaggacccctacccctcggccgacttcccg
ggggacgatgaagaagacgagcccgagatcccagtgagcccccgaccgaggcccttggcc
gagctgcagctgaaagagaaagccgtgcccatcccggaagccagttccttcttcatcttc
agccccaccaacaagtgggtggcccccggatccgtcctgtgtcaccgcatcgtcaacgcc
acctggttcaccaacttcatcctgctgttcatcatgctcagcagcgccgcgctggctgcc
gaggaccccatccgggctgagtccatgcggaaccagatcctcgggcattttgacattgcc
ttcacctctgtcttcactgtggagattgtcctcaagatgacgacctacggcgccttcctg
cacaaaggctctttctgccgcaactacttcaacatcctggacctgctggtggtggctgtg
tccctcatctccatgggactcaagtccagctccatctccgtggtgaagattctgagggtg
ctgagggtgctccgacccctgcgggccatcaacagagccaaggggctgaagcacgtggtg
cagtgtgtgttcgtggccatccgcaccatcgggaacatcgtcctcgtcaccgccctcctg
cagttcatgttcgcctgcatcggggtccagctcttcaagggcaagttcttccgctgcaat
gacttgtccaagatgaccgaggaggagtgcaggggccactactacgtgtacgaggacggg
gaccccgcgcgggtgggggtgcagccgcgccggtggctacactccgacttccacttcgac
aacgtgctgtcggccatgatgtccctcttcacggtgtccaccttcgaggggtggccgcag
ctcctgtacgaggccatcgactcgcacgaggaggacaagggtcccgtctacaacaaccgg
gtggaggtggccatcttcttcctcatctacatcatcctcgtcgccttcttcatgatgaac
atcttcgtgggcttcgtcatcgtcaccttccaggagcagggcgagacggagtacaagaac
tgtgagctggacaagaaccagcgccagtgtgtgcagtacgccctgaaggcccggccgctg
aagtgctacatccccaagaacccgtaccagtaccaggtgtggtacgtggtcacctcctcc
tacttcgagtacctgatgtttgccctcatcatgctgaacaccgtctgcctgggcatgcag
cactacaaccagtcagagcagatgaaccacatctcagacatcctcaacgtggccttcacc
atcatcttcaccctggagatggtcctcaagctcgtggcgttcaaggccaggggctacttc
ggggacccctggaacgtgttcgacttcctgatcgttgtcggcagcatcatcgacgtcatc
ctcagtgagatcgatactttcctggcctccagcgggggactgtattgcctgggtggaggc
tgcgggaacgttgacccggacgagagcgcccgcatctccagcgccttcttccgcctcttc
cgcgtcatgaggctgatcaagctgctgagccgcgcggagggcgtgcgcacgctgctctgg
accttcatcaagtccttccaggccctgccctacgtggccctgctgatcgtcatgctcttc
ttcatttacgcggtcatcggcatgcagatgttcgggaagatcgccctggtggacgggacc
cagataaaccggaacaacaatttccagaccttcccgcaggctgtgctgctgctgttcagg
tgcgcgacgggcgaggcgtggcaggagatcctgctggcctgcagctcgggcaagctgtgc
gaccccgagtcggagttcgcccccggcgaggagcactcctgcggcaccggcttcgcctac
tactacttcgtcagcttctacatgctctgcgccttcctgatcatcaacctcttcgtggct
gtgatcatggacaacttcgactacctcacgcgagactggtccatcctgggccctcaccac
ttggacgagttcaaggccatctgggcagagtacgacccggaggccaagggccggatcaaa
cacctggacgtggtgactctgctgagaaggatccagccacccctgggctttgggaagttc
tgcccccaccgggtggcgtgtaagcgcctggtgggcatgaacatgcctctgaacagcgat
ggcactgtcactttcaacgccaccctcttcgccctggtccgtacggccctcagaatcaag
acggaaggtaacttcgagcaggccaacgaggagctgagggccatcatcaagaagatctgg
aagagaaccagcatgaagctgctggaccaggtcatcccgcccataggagatgacgaggtg
actgtggggaagttctatgccacgttcctcatccaggagcacttccggaagttcatgaag
cgccaggaggagtattatgggtatcggcccaagaaggacactgtacagatccaggctgga
ctgaggacaatcgaagaggaggcggcccctgagatccgccggacaatctcaggagacctg
accgctgaggaggagctggagagggccatggtggaggccgcgatggaggaggggatcttc
cggaggacgggaggcctgtttggcgccgtggacaacttcctggaaaggaccaactccctg
gcgcccgccatggccagccagaggcccctccagttcgcggagatagagatggaggagctg
gagtcgcctgtcttcttggaggacttccctcaggatcccagagtcagcccgcttgcccgc
gccaacgccaacaacgccaacaacgccaacgctgccggcggcaacggcagccctggcggc
cgccgggggtgctccagcatccgctacgtgagggagtgcccgggagagtcggcgacgccc
gctgccggaggaggagcccagggtcagtgtcctcccggaggcctggggaccggcccttcc
ccacagctgggagccgggctgggggggctggcgtgggggctggcatgggggcctgtcgca
gcggggaccagccggggccgagtggggagctggccggtccagcccctcatccaggcagag
gagcagggcgccctccaggtgatgggggggaccggaccccaggacgcctcttcccgtggg
tcttggctgaggctcctgggaagagtgggttacccggggcccagtgcctccagcttcccg
ggggtctctgcttctgtgcacttgcaacagcgccctagggcggagccccccacgcctggg
tctctgcccgaggatgccccccgcagcggctggccccacaagcgcccttccaagtgccca
gctcccagcacggccctgctgatccaggaggccctggttcgagggggcctggagaccctg
gcagctgatgctggcttcgtcacggccacaggccaggccctggcggacgcctgccggatg
gaaccagaggacgtggaggtggcggcgacagagctgctgaggggacgagggtcccctgtg
ggcacggccggcgcccagggcggcctgagcctcaggtcctccctgggcagcctggaccag
tgtcagggctcccaggagaccctaatcccacccgggctgtga

KEGG   Rousettus aegyptiacus (Egyptian rousette): 107514999
Entry
107514999         CDS       T06036                                 

Gene name
CACNA1F
Definition
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1F isoform X1
  KO
K04853  voltage-dependent calcium channel L type alpha-1F
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04020  Calcium signaling pathway
ray04022  cGMP-PKG signaling pathway
ray04024  cAMP signaling pathway
ray04260  Cardiac muscle contraction
ray04261  Adrenergic signaling in cardiomyocytes
ray04270  Vascular smooth muscle contraction
ray04723  Retrograde endocannabinoid signaling
ray04725  Cholinergic synapse
ray04726  Serotonergic synapse
ray04727  GABAergic synapse
ray04911  Insulin secretion
ray04912  GnRH signaling pathway
ray04921  Oxytocin signaling pathway
ray04924  Renin secretion
ray04925  Aldosterone synthesis and secretion
ray04927  Cortisol synthesis and secretion
ray04929  GnRH secretion
ray04934  Cushing syndrome
ray04935  Growth hormone synthesis, secretion and action
ray05010  Alzheimer disease
ray05020  Prion disease
ray05022  Pathways of neurodegeneration - multiple diseases
ray05410  Hypertrophic cardiomyopathy
ray05412  Arrhythmogenic right ventricular cardiomyopathy
ray05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107514999 (CACNA1F)
   04020 Calcium signaling pathway
    107514999 (CACNA1F)
   04024 cAMP signaling pathway
    107514999 (CACNA1F)
   04022 cGMP-PKG signaling pathway
    107514999 (CACNA1F)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    107514999 (CACNA1F)
   04929 GnRH secretion
    107514999 (CACNA1F)
   04912 GnRH signaling pathway
    107514999 (CACNA1F)
   04921 Oxytocin signaling pathway
    107514999 (CACNA1F)
   04935 Growth hormone synthesis, secretion and action
    107514999 (CACNA1F)
   04924 Renin secretion
    107514999 (CACNA1F)
   04925 Aldosterone synthesis and secretion
    107514999 (CACNA1F)
   04927 Cortisol synthesis and secretion
    107514999 (CACNA1F)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    107514999 (CACNA1F)
   04261 Adrenergic signaling in cardiomyocytes
    107514999 (CACNA1F)
   04270 Vascular smooth muscle contraction
    107514999 (CACNA1F)
  09156 Nervous system
   04727 GABAergic synapse
    107514999 (CACNA1F)
   04725 Cholinergic synapse
    107514999 (CACNA1F)
   04726 Serotonergic synapse
    107514999 (CACNA1F)
   04723 Retrograde endocannabinoid signaling
    107514999 (CACNA1F)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107514999 (CACNA1F)
   05020 Prion disease
    107514999 (CACNA1F)
   05022 Pathways of neurodegeneration - multiple diseases
    107514999 (CACNA1F)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    107514999 (CACNA1F)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    107514999 (CACNA1F)
   05414 Dilated cardiomyopathy
    107514999 (CACNA1F)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107514999 (CACNA1F)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ray04040]
    107514999 (CACNA1F)
Ion channels [BR:ray04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   107514999 (CACNA1F)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 107514999
NCBI-ProteinID: XP_016008764
LinkDB
Position
Unknown
AA seq 1978 aa
MSASEGGKDITPDPSPANGTGPGPEWGLCSGPPESGGEIGGTLGLGTPKRRTQHSKHKTV
TVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDS
NTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLL
EQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHI
ALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRVCTLNQTECR
GRWAGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGS
FFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLRGYLDWIMQAEELDIEDPS
ADDNFCSVAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSMAE
TPGDEEEEEGALASCTFCLNKIMKTRVCRQLRRANRGLRACCRRAVKSNACYWAVLLLVF
LNTLTIASEHHGQPIWLTQTQEYANKVLLCLFTVEMLLKLYGLGPSAYVSSFFNRFDCFV
VCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLL
LLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQALLTVFQILTGEDWNVVMYDG
IMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLASGDTGTAKDKGREKCTEE
KPPQENRALVPGEENEEEEGTRNEGAGMEEEEEEDEEEEEGGAGRVELLQEVVPKEKVVP
IPEGSAFFCLSQTNSLRKACHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHIL
GYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNLLDLLVVSVSLISFGIHSSAISV
VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKG
KFYSCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVST
FEGWPALLYKAIDAHAEDEGPIYNYHVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQG
EQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNT
VALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFADAWNTFDALIVVG
SVVDIAVTEVNNGGHLGESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSF
QALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEA
WQEIMLATLPGNRCDPESDFGPGEEFTCGSNFAIAYFISFFMLCAFLIINLFVAVIMDNF
DYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVA
CKRLVAMNMPLNSDGTVTFNATLFALVRTSLKIKTEGNLEQANQELRIVIKKIWKRMKQK
LLDEVIPPADEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLGTEAPPSTSSALQAGLRSL
QDLGPEIRQALTCDTDQEEEEEEEEERQQGEEKEDKDPETYKAPIGSQPPSRRRSSVISV
SLPAGDKLPDSLSLGPSDDDGGAPNSRQFSVPQAGSHTHRRSSGTLIFTIPEEGSSQPKG
TEEEEKQNEEEEVPSRLSYLDEQSGTPLHPMLLPPHRPQRYVGEHRAPHRRLLPPTPAGR
KPSFTIQCLRRQSSCEDLPIPGTYHRGRNSGPSRTQGSWATPPQRGRLLYAPLLLVEEGT
AGDGYLAKSSGPLRTFTCLHVPGTHSDPSHGKRGSADSLVEAVLISEGLGLFARDPHFVA
LAKQEIADACRLTLDEMDSAASDLLAQGTSSFYSDEESIRSRFDEEDLRDEMACVHAL
NT seq 5937 nt   +upstreamnt  +downstreamnt
atgtcggcttctgaaggcgggaaagatatcaccccagatcccagtccagccaatgggaca
ggccctggtcccgaatggggcctgtgctctgggcccccagaatcagggggtgaaatcggc
ggaacattgggcctggggacccctaagcgaaggactcagcacagtaagcacaagacggtc
acagtggccagtgcccagaggtcaccccgggcactcttctgcctcaccctggccaaccct
ctgcggcggtcttgcattagcatcgtagaatggaagcctttcgacattctcatcttgctg
accatctttgccaactgcgtagccctgggggtctatatccccttcccagaagatgactcc
aacactgccaaccacaacctggagcaggtagagtacgtattcctggtgattttcactgtg
gagacggtgctcaagattgtggcctatgggctggtgctccatcccagcgcttacatccgc
aatggctggaacctactcgacttcatcatcgtcgtggtcgggttgttcagtgtgctactg
gagcaaggccccggacgacctggggatgctccgcataccggggggaagccggggggcttc
gatgtgaaggcgttgcgggcatttcgggtgctgcggccactgaggctggtgtctggggtc
ccaagtctgcacatagtgctcaattccatcatgaaagcactggtgccactgctgcacatc
gcactgctagtgctcttcgtcatcatcatttatgccatcatcggactcgagttgtttctc
ggtcgcatgcacaagacttgctacttcctgggatctgacatggaagccgaggaggaccca
tcaccttgtgcgtcttcgggctcagggcgtgtgtgcacgctgaatcagaccgagtgccgg
gggcgctgggcagggcccaatggaggcatcaccaacttcgataacttcttcttcgccatg
cttacggtcttccagtgcgtcaccatggaaggctggaccgacgtgctctactggatgcag
gatgcgatggggtatgagctgccttgggtgtatttcgtgagtctcgtcatctttgggtcc
ttctttgtcctcaatcttgtacttggcgtcctgagtggggaattctccaaggagagggag
aaggcaaaagcaagaggggacttccagaagctgcgagagaagcaacagctggaggaggac
ctgcggggctacctggactggatcatgcaggcagaagagctggacattgaagacccctca
gctgatgacaacttttgttctgtggctgaagaaggccgggctggccaccggccacaactg
gcagagctgaccaatcggagacgtggacgtctgcgctggttcagtcactccacccgctcc
acacactccaccagcagccatgccagcctcccagccagtgacacgggttcgatggcagag
actccaggcgatgaagaagaggaggagggggctctagccagttgtacattctgcttaaat
aagattatgaaaaccagggtctgccgccagctccgtcgagccaaccgaggccttcgggca
tgctgccggagggctgtgaaatccaatgcctgttattgggccgttctgctgcttgtcttc
ctcaacacgttgaccatcgcctcagagcaccacgggcagcctatatggctcacacagacc
caggagtatgccaacaaagtgttgctctgtctattcacggtggaaatgcttctcaagctc
tatggtctgggcccctccgcctatgtttcctccttcttcaaccgctttgactgctttgtg
gtctgtgggggcatcctggaaaccaccctggtggaggtgggagccatgcagcccctgggt
atctcagtgctccggtgtgtgcgcctcctcaggatctttaaagtcaccaggcactgggca
tctctaagcaatttggtggcatccctactcaattcaatgaaatccatcgcatctttgctg
cttctcctcttcctctttatcatcatcttctccctgcttggcatgcagctgtttgggggc
aagttcaactttgaccagacccacaccaagcgaagcacctttgacaccttcccccaggcc
ctcctcactgtctttcagatcctgacgggcgaggactggaatgtggtcatgtatgatggt
atcatggcctatggcggccccttcttcccagggatgctggtgtgcatctatttcatcatt
ctcttcatctgcggcaactacatcctgttgaacgtgtttcttgccattgctgtggacaat
ctggctagtggagacacaggcactgccaaggacaagggcagggagaaatgtactgaagag
aaacccccacaggagaatagagcattggtgcctggtgaggaaaatgaggaagaggagggt
acaagaaatgaaggagcaggcatggaggaagaggaggaagaggatgaggaagaggaggaa
gggggtgcagggcgtgtggaactcctacaggaagttgtacccaaggagaaggtggtgccc
atccctgagggcagtgccttcttctgcctcagccaaaccaactcattgaggaaggcctgc
cacaccctcattcaccatcatgtcttcactaatcttatcctggtgttcatcatcctcagt
agtgtgtctctggctgctgaggaccccatccgagcccactccttccgcaaccatattctg
gggtattttgattatgccttcacatccattttcactgtggagattctactaaagatgacg
gtgtttggggccttcctgcaccgaggctccttctgccgtagctggttcaatctgttggat
ttgctggtggtcagcgtttctctcatctcctttggcatccactccagtgccatctcggtg
gtgaagattctgcgcgtactccgagtacttcggccccttcgagccatcaaccgggccaag
ggcctcaagcacgtggtacagtgtgtgttcgtggccatccggaccatcggaaatatcatg
attgtaaccacactcctgcaattcatgtttgcctgcattggcgtgcagcttttcaagggg
aaattctacagttgcactgatgaagccaaacacacccctcaagaatgcaagggctccttc
ctggtctatcctgatggagatgtgtcacggcccctggtccgggagcggctctgggtcaac
agcgatttcaactttgacaatgtcctttcagccatgatggctttgttcactgtctccacc
ttcgaaggctggcctgcgctgctatacaaggccattgatgcacacgcagaggatgagggc
cctatctataattaccacgtggagatatcagtgttcttcattgtctacattatcatcatc
gcattcttcatgatgaacatctttgtgggctttgtcatcatcaccttccgtgcccagggt
gagcaggagtaccaaaactgtgaactggacaagaaccagcgccagtgcgtggagtacgcc
ctcaaggcccagccactccgccgttacatccccaagaacccgcatcagtatcgtgtgtgg
gccactgtgaactctgctgccttcgagtatctcatgttcctgctcatcctgctcaacacg
gttgctctagccatgcagcactatgagcagactgctcccttcaactatgccatggacatc
ctcaacatggtcttcactggcctcttcactattgagatggtgctcaaaatcatcgccttc
aaacccaagcattattttgccgatgcctggaacacatttgatgctcttattgtggtgggc
agcgtagtggacattgccgtcactgaagttaataatggtggccaccttggcgagagctct
gaggacagttcccgcatttccatcaccttctttcgtctcttccgagttatgaggctggtc
aagcttctcagtaagggtgaaggaatccggacactgctctggacattcattaagtccttc
caggccttgccctatgttgctcttctcatcgcaatgatattcttcatttacgcagtcatt
gggatgcagatgtttggcaaggtggctcttcaagatggcacacagatcaaccgaaacaac
aacttccagacttttccacaggctgtactacttctcttcaggtgtgccactggtgaggca
tggcaggagataatgcttgccacccttcccgggaatcggtgtgaccctgagtctgacttc
ggccctggagaggaatttacctgtggtagcaattttgccatcgcctattttatcagcttc
tttatgctttgtgccttcctgatcataaatctctttgtggctgtgatcatggacaacttt
gactatctaaccagagactggtctatcctgggtccccatcacctcgatgaattcaagagg
atctggtctgaatatgaccctggggccaagggccgcatcaagcacctggatgtggttgcc
ctgctgaggcgcatccagcccccgctgggattcgggaagctgtgcccacaccgagtagct
tgcaagagacttgtggcaatgaacatgcccctcaactcagatgggacggtgacattcaac
gccacactctttgccctggttcggacatccctgaagatcaaaacagaagggaacctggag
caagccaatcaggagctgcgaatcgtcatcaaaaagatctggaagcggatgaagcagaag
ctgctagatgaagtcatcccccctgctgatgaggaagaggtcaccgtgggcaaattctat
gccacctttctgatccaggactacttccgcaaattccggcggaggaaagaaaaaggacta
ctggggaccgaagcccccccaagcacatcctctgcccttcaggctggcctgaggagccta
caggacttaggtcctgagatccggcaagcactcacttgtgacacagaccaggaggaagag
gaggaggaagaagaagaaaggcagcagggagaggagaaggaagataaggacccagaaaca
tacaaagccccaataggctcccaacccccgtctcgccgccggagctccgtgatttctgta
tctctgcctgctggggacaaacttccagattcactttcccttgggcccagtgatgatgat
ggtggagctcccaactccagacagttcagtgtgccccaggctggatcccacactcacaga
agaagctctgggactctcattttcaccattccagaagaaggaagttctcaacccaaagga
actgaagaagaagagaaacagaatgaggaagaagaagtccccagccggctctcctactta
gatgagcaatcagggactcccctgcaccccatgctcttgccacctcacagaccccagaga
tatgtgggcgagcaccgtgcaccacatcgccgtctgctgcccccaacacctgcaggtcgg
aagccctctttcacaattcaatgtctgcggcgccagagcagttgtgaagatttacccatc
ccaggcacctatcatcgtgggcgcaattcagggcctagcaggacacagggttcctgggca
acccctcctcagagaggtcggctcctgtatgccccactgttattagtggaggagggtaca
gcaggggacggatacctcgccaaatccagcggtccactgcgcaccttcacctgtctgcac
gtgcctggaacccattcagacccaagccatggcaagaggggcagtgccgacagcctggtg
gaggctgtgctcatctccgagggtctgggcctctttgcccgagacccacactttgtggcc
ctggccaagcaggagattgcggatgcatgtcgcctgacactggatgagatggacagtgct
gccagtgatctgctggcacaggggaccagctcattttatagtgatgaggagtctatccgc
tcccgctttgatgaggaggacctgagagatgagatggcctgcgtccatgccctctga

KEGG   Rousettus aegyptiacus (Egyptian rousette): 107516535
Entry
107516535         CDS       T06036                                 

Gene name
CACNA1D
Definition
(RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1D
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04020  Calcium signaling pathway
ray04022  cGMP-PKG signaling pathway
ray04024  cAMP signaling pathway
ray04218  Cellular senescence
ray04260  Cardiac muscle contraction
ray04261  Adrenergic signaling in cardiomyocytes
ray04270  Vascular smooth muscle contraction
ray04530  Tight junction
ray04713  Circadian entrainment
ray04723  Retrograde endocannabinoid signaling
ray04724  Glutamatergic synapse
ray04725  Cholinergic synapse
ray04726  Serotonergic synapse
ray04727  GABAergic synapse
ray04728  Dopaminergic synapse
ray04911  Insulin secretion
ray04912  GnRH signaling pathway
ray04921  Oxytocin signaling pathway
ray04924  Renin secretion
ray04925  Aldosterone synthesis and secretion
ray04927  Cortisol synthesis and secretion
ray04929  GnRH secretion
ray04930  Type II diabetes mellitus
ray04934  Cushing syndrome
ray04935  Growth hormone synthesis, secretion and action
ray04973  Carbohydrate digestion and absorption
ray05010  Alzheimer disease
ray05020  Prion disease
ray05022  Pathways of neurodegeneration - multiple diseases
ray05031  Amphetamine addiction
ray05410  Hypertrophic cardiomyopathy
ray05412  Arrhythmogenic right ventricular cardiomyopathy
ray05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107516535 (CACNA1D)
   04020 Calcium signaling pathway
    107516535 (CACNA1D)
   04024 cAMP signaling pathway
    107516535 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    107516535 (CACNA1D)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    107516535 (CACNA1D)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    107516535 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    107516535 (CACNA1D)
   04929 GnRH secretion
    107516535 (CACNA1D)
   04912 GnRH signaling pathway
    107516535 (CACNA1D)
   04921 Oxytocin signaling pathway
    107516535 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    107516535 (CACNA1D)
   04924 Renin secretion
    107516535 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    107516535 (CACNA1D)
   04927 Cortisol synthesis and secretion
    107516535 (CACNA1D)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    107516535 (CACNA1D)
   04261 Adrenergic signaling in cardiomyocytes
    107516535 (CACNA1D)
   04270 Vascular smooth muscle contraction
    107516535 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    107516535 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    107516535 (CACNA1D)
   04727 GABAergic synapse
    107516535 (CACNA1D)
   04725 Cholinergic synapse
    107516535 (CACNA1D)
   04728 Dopaminergic synapse
    107516535 (CACNA1D)
   04726 Serotonergic synapse
    107516535 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    107516535 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    107516535 (CACNA1D)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107516535 (CACNA1D)
   05020 Prion disease
    107516535 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    107516535 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    107516535 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    107516535 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    107516535 (CACNA1D)
   05414 Dilated cardiomyopathy
    107516535 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    107516535 (CACNA1D)
   04934 Cushing syndrome
    107516535 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ray04040]
    107516535 (CACNA1D)
Ion channels [BR:ray04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   107516535 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel Rer1
Other DBs
NCBI-GeneID: 107516535
NCBI-ProteinID: XP_016011838
LinkDB
Position
Unknown
AA seq 2182 aa
MMMMMMMKKMQHQRQQQADHANEANYARGTRFSLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDVVAEEDPAPCAFSGNGRQCSANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGENQGCCGSLWCWWKRRGAAKAGPSECRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEEDEPEVPAGPRPRRISELNMKEKIVPIPEGSAFFILSKTNPIRVGC
HKLINHHVFTNLILVFIMLSSASLAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMT
TFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAK
GLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLF
ILYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPELLYKAIDSNGENIG
PIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYA
LKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDI
LNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPV
PTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAM
LFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGK
LCDPESDYSPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGP
HHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLN
SDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDD
EVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAIS
CDLQDDEPEETKGEEEEDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIP
PASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPSSTNANLNNANMSKAAPGKRPSIGNLEH
VSENGHHSSHKHDHEPQRRSSIKRTRYYETYIRSDSGDEQFPTICREDPEIHSYFRDPRC
LGDQEYFSGEECYEDDSSPTESRQNYIYYNRYPGSNLDFERPRGYHHPQGFLEDDNSPIG
YDSRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVPPSPTFPHRTALPLHLMQQQIM
AVAGLDSSKAQKYSPSHSTRSWVTPPATPPHRDWTPCYTPLIQVEQPEALDQVNGSLPSL
HRSSWYTDEPGISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPK
FVSATKHEIADACDLTIDEMESAASNLLNGNVHPRANGDMGLVSSRQDYELQDFGPGYSD
EEPDPGREEEDLADEMICITTL
NT seq 6549 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaagcaaactatgcaagaggcaccagattctctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcttgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctccgctcccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcctccaacagc
cgacctgcccgcgcccttttctgtttatcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcatatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggtaaccactctagtggcaaatcgggaggctttgatgtcaaagccctccgc
gcctttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggtccccctccttcacattgcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatgtcgtagctgaagaggacccagcaccgtgtgcgttctca
gggaatggacgccagtgttctgccaatggcacggagtgtaggagtggctgggttggtcca
aatggaggcatcaccaactttgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggttggacagatgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gtacttggtgtccttagtggagaattctcaaaagaaagagagaaagctaaagcacgagga
gatttccagaagctccgggaaaagcagcagctagaagaggatctaaagggctacttggac
tggattacccaagcagaagatattgaccctgagaatgaggaagaaggaggagaggagagc
aaaagaaataccagcatgccgaccagcgagacagagtctgtgaacacagagaacgtaagt
ggcgaaggcgagaaccaaggctgctgtggaagtctctggtgctggtggaaaagaagaggt
gcggccaaggctgggccctctgagtgtcggcggtggggtcaagccatctcaaaatccaag
ctcagccgacgctggcgtcgctggaaccgattcaatcgcagaagatgtagggctgctgtg
aagtctgtcacattttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctctgagcactataaccagcctgactggttgacgcagattcaagatatcgcgaacaaa
gtcctcctggctctgttcacctgcgagatgctagtaaaaatgtacagcttgggtctccag
gcatatttcgtctctctctttaatcggtttgattgcttcgtggtgtgtggcggaattacg
gaaacgatcttggtggagctggaaatcatgtctcccctggggatctccgtatttcggtgt
gtgcgcctcttacgcattttcaaagtgactaggcactggacgtccctgagtaacttagtg
gcatccttgttaaactccatgaagtccattgcgtcgctgttgcttctgctctttctcttc
atcatcatcttttccctgcttgggatgcagctgtttggaggcaagtttaattttgacgaa
acgcagaccaagcggagcacctttgacaatttccctcaagcacttctaacagtgttccag
attctgacaggtgaagactggaacgctgtgatgtatgatggcattatggcatatgggggc
ccgtcatcttcgggaatgatcgtctgcatctacttcatcatactcttcatttgtggtaac
tatatcctactgaatgtcttcttggccatcgctgtagacaatttggctgatgccgaaagt
ttgaatactgctcagaaagaagaagctgaagaaaaggaaaggaagaagattgctaggaaa
gaaagcctagaaaataaaaagaacaacaaaccggaagtcaatcagatagccaacagtgac
aacaaggttacaattgatgactaccgagaagaggatgaggacaaggacccctacccacct
tgcgatgtaccagtaggtgaagaggaggaggaagaggaggaggaggatgaacctgaggtt
cccgctggaccccgtcctcgcaggatctcagagttgaacatgaaggagaaaatcgtcccc
atccccgaagggagcgccttcttcattcttagcaagaccaatccgatccgcgtgggctgc
cacaagctcatcaaccaccacgtattcaccaatctcatcctcgtcttcatcatgctgagc
agtgcctccctcgccgccgaggaccccatccgcagccactccttccggaacaccatactg
ggttactttgactatgctttcacagccatctttactgtcgaaatcctgttaaagatgacg
acttttggagctttcctgcacaaaggagccttttgcaggaactacttcaatttgctggat
atgctggttgttggggtatctctggtgtcatttgggatccaatccagtgctatttctgtt
gtgaagattctgagggtcttaagggtcctgaggccactcagggcaatcaacagagcgaaa
ggactcaagcacgtcgtccagtgcgtctttgtggccatccggacaatcggcaacatcatg
attgtcaccacccttctccagttcatgtttgcctgcatcggggtccagttgttcaaggga
aagttctatcgctgcacagatgaggccaaaagtaatcctgaagaatgcagggggcttttc
atcctctacaaggatggagatgttgataatcctgtggtgcgtgagaggatctggcaaaac
agcgatttcaactttgacaatgtcctttctgctatgatggcccttttcacggtctccaca
tttgagggctggcctgagttgctgtacaaagccattgactcaaacggagagaacatcggc
cccatctacaactaccgtgtggagatctccatcttcttcatcatctacatcatcatcgtc
gcttttttcatgatgaacatcttcgtgggttttgtcatcgtcaccttccaggagcaggga
gagaaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgcc
ttgaaagcacgtcccttgcggagatacatccccaaaaacccttaccagtacaagttctgg
tatgtggtgaactcctcgcctttcgaatacatgatgttcgtcctcatcatgctcaacaca
ctctgcttggccatgcagcactatgagcagtccaagatgtttaatgatgccatggacatc
ttgaacatggtcttcactggggtgttcacagtcgagatggttttgaaagtcattgcattt
aaacctaaggggtattttagtgacgcctggaatacgtttgactccctcatcgtaatcggc
agcattatagacgtggccctcagcgaagccgacccaactgaaagtgaaaatgtccctgtc
ccaactgctacacctgggaactctgaagagagcaatagaatctccatcacctttttccgt
cttttccgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacactg
ctgtggacttttattaagtcctttcaggccctcccatatgtcgcccttctcatagccatg
ctgttcttcatctatgcggtcatcggcatgcagatgtttgggaaagttgccatgagagat
aacaaccagatcaaccggaacaacaatttccagacctttccccaggcggtgctgctgctc
ttcaggtgtgcgacaggtgaggcctggcaagagatcatgctggcctgcctcccggggaag
ctctgtgaccccgagtcggactacagccctggggaggagtacacgtgtgggagcaacttt
gccattgtgtatttcatcagtttttacatgctctgtgcatttctgatcatcaacctgttt
gtggctgtcatcatggacaactttgattatctgactcgggactggtctattctggggcct
caccatttagacgaattcaaaagaatatggtcagaatatgaccccgaggcaaaaggaagg
atcaagcacctcgacgtggtcactctgctccgccgtatccagcctcccctggggtttggg
aagttatgcccacacagagtagcctgtaagagactggttgccatgaacatgcctcttaac
agtgatgggacagtaatgtttaatgcaaccctgtttgctttggttcgaacagctctgaaa
atcaagacggaagggaacctggaacaagctaatgaagaactccgagctgtgataaagaaa
atctggaagaaaaccagcatgaaactgcttgaccaagttgtccctccagctggtgatgat
gaggtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattc
aagaaacggaaagaacaaggactggtgggaaaataccctgcgaagaacaccacaattgcc
ctacaggcgggattaaggacactgcatgacatcgggccagaaatccggcgtgctatatca
tgtgatttgcaagatgacgagcccgaggaaacaaaaggagaggaagaggaagatgtattc
aaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagat
tcccttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattcca
cctgcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataac
catcataaccataattccataggaaagcaagttcccagctcaacaaatgccaatctcaat
aatgccaatatgtccaaagctgcccctggaaagcggcccagcattgggaaccttgagcat
gtgtctgaaaatgggcatcattcctcccacaagcatgaccatgagcctcaaagaaggtcc
agtattaaaagaacccgctattatgaaacttatattaggtccgactcaggagatgaacag
ttcccaactatttgccgagaagacccagagatacacagctacttcagggacccccgctgc
ttgggagaccaggagtacttcagtggggaggaatgctacgaggatgacagttcgccaact
gagagcaggcaaaactacatttactacaaccgatacccaggcagcaacttggacttcgag
cggccccgaggctaccatcacccccaaggcttcttggaggacgacaactcacccattggc
tatgattcccggagatctccaagaagacgtctgctacctcccaccccaacatcccaccga
agatcctccttcaacttcgagtgcctgcgccgacagagcagtcaggaggaggtcccaccg
tcccccaccttcccccaccgcacggccctgcctctgcacctgatgcagcaacagatcatg
gcagttgcaggcctagattcaagtaaagcccagaagtactcaccaagccactcaacacgg
tcatgggtcactcctccagcgaccccaccacaccgggactggactccatgctacaccccg
ctcatccaggtcgagcagccggaggccctagaccaggtcaatggtagcctgccatccctg
caccgcagctcgtggtacacggacgagcctggcatctcctatcggaccttcacaccagcc
agcctgactgtccccagcagcttccgcaacaaaaacagcgacaagcagaggagcgcagac
agcttggtagaggcagtcttgatatccgaaggcttaggacgatatgcaagggacccaaaa
ttcgtgtcagcaacgaaacacgaaatcgccgatgcctgtgacctaacaatcgacgagatg
gagagtgcagccagcaacctgcttaatgggaacgtgcatccccgggctaatggggacatg
ggcctcgtctcaagcaggcaggactatgagcttcaggacttcgggccaggctacagcgac
gaagagccagaccccgggagagaggaggaggacctggcagatgaaatgatatgtattacc
accctgtag

KEGG   Rousettus aegyptiacus (Egyptian rousette): 107519399
Entry
107519399         CDS       T06036                                 

Gene name
CACNA1A
Definition
(RefSeq) voltage-dependent P/Q-type calcium channel subunit alpha-1A isoform X1
  KO
K04344  voltage-dependent calcium channel P/Q type alpha-1A
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04020  Calcium signaling pathway
ray04721  Synaptic vesicle cycle
ray04723  Retrograde endocannabinoid signaling
ray04724  Glutamatergic synapse
ray04725  Cholinergic synapse
ray04726  Serotonergic synapse
ray04727  GABAergic synapse
ray04728  Dopaminergic synapse
ray04730  Long-term depression
ray04742  Taste transduction
ray04930  Type II diabetes mellitus
ray05017  Spinocerebellar ataxia
ray05032  Morphine addiction
ray05033  Nicotine addiction
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107519399 (CACNA1A)
   04020 Calcium signaling pathway
    107519399 (CACNA1A)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    107519399 (CACNA1A)
   04727 GABAergic synapse
    107519399 (CACNA1A)
   04725 Cholinergic synapse
    107519399 (CACNA1A)
   04728 Dopaminergic synapse
    107519399 (CACNA1A)
   04726 Serotonergic synapse
    107519399 (CACNA1A)
   04730 Long-term depression
    107519399 (CACNA1A)
   04723 Retrograde endocannabinoid signaling
    107519399 (CACNA1A)
   04721 Synaptic vesicle cycle
    107519399 (CACNA1A)
  09157 Sensory system
   04742 Taste transduction
    107519399 (CACNA1A)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    107519399 (CACNA1A)
  09165 Substance dependence
   05032 Morphine addiction
    107519399 (CACNA1A)
   05033 Nicotine addiction
    107519399 (CACNA1A)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    107519399 (CACNA1A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ray04040]
    107519399 (CACNA1A)
Ion channels [BR:ray04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   107519399 (CACNA1A)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel DUF2207
Other DBs
NCBI-GeneID: 107519399
NCBI-ProteinID: XP_016017538
LinkDB
Position
Unknown
AA seq 2580 aa
MWKSSWVLDPMFSPYSYYDALHNGGLGAPGPAPLGPPSVPQVPQSHRMSSICEGPPLKRR
GGLVDHRDVILAHQAHKIHSTPQARRKEWEMARFGDEMPARYGGGGSGAAAGVVVGAGGG
RGAGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKY
AKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGI
KIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFDLRTLRAVRVLRPLKLVSGIP
SLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQGESPA
PCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDA
SGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELN
GYMEWISKAEEVILAEDETDGEQRHPFDVGALRRATIKKSKTDLLNPEEAEGQLADIASV
GSPFARASIKSAKLENSTFFHKKERRVRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHY
NQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWA
VIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFA
LLGMQLFGGQFNFDEGTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQGGMV
FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEVAEV
SPLSAASMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREALYNEMDPDERWKATYA
RHLRPDMKTHLDRPLVVDPQENRNNNTNKSRAAEPTVDQRLGQQRAEDFLRKQARYHDRA
RDPSGSVGLDARRPWAGSQEAELSREGPYGRESDHHAREGGLEPPGFWEGEAERPKAGDP
HRRHAHRPGGSRESRSGSPRTGADGEPRRHRAHRRPGEEALEDKAERRSRHREGCRPARG
GEGEGPDGGERRRRHRHGPPATYDMETRREDRERRHRRRKDNQGSGVPVSGPNLSTTRPI
QQDLGRQDPPLAEDIDNMKNNKLATAESASPHDSLGHSGLPQSPAKMGNSTHPGSTPAPP
ATATNPQNTASRRVPNNPGNPSNPGPPKTPENSLIVTNPSSTQTNSAKTARKPDHTTVDI
PPACPAPLNHTVVQVNKNANPDPLPKKEEKKKEEEEDDPGEDGPKPMPPYSSMFILSTTN
PLRRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFE
MVIKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFAFTSSTRGNSKGKDINTIKSLRV
LRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCT
DESKEFEKDCRGKYLLYEKNEVKARDREWRKYEFHYDNVLWALLTLFTVSTGEGWPQVLK
HSVDATFENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSL
EKNERACIDFAISAKPLTRHMPQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKF
YGASLAYENALRVFNIVFTSLFSLECLLKVMAFGILNYFRDAWNIFDFVTVLGSITDILV
TEFGNPNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFI
YAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSC
LSGKPCDKNSGILTPECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILG
PHHLDEYVRVWAEYDPAAWGRMPYPDMYQMLRHMSPPLGLGKKCPARVAYKRLLRMDLPV
ADDNTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEMMAIWPNLSQKTLDLLVTP
HKSTDLTVGKIYAAMMIMEYYRQSKAKKLQAMREEQNRTPLMFQRMEPPSPTQEGVPGQN
ALPSTQLDPGGGLMAHEGGIKESPSWVTQRAQEMFQKTGTWSPERGPPTDMPNSQPNSQS
VEMREMGRDGYSDSERYLPMEGQARATSMPRLPAENQRRRGRPRGNNLSTISDTSPMKRS
ASVLGPKARRLDDYSLERVPPEENQRHHQRRRDRSHRASERSLGRYTDVDTGLGTDLSMT
TQSGDLPSKERDQERGRPKDRKHRQHHHHHHHHHPPPPDKERYAQERQDHRARTRDQRWS
RSPSEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHVSYSPVIRKA
GGMGPPQQQQQPVARPGRAAPSGPRRYPGPAAEPLAGERPPGGHGSSRSPAMERRGPARS
ESPRACRHSGARWPASVAHASEGPLGSRHHGYYRGSDYDEANGPGVSGDDGPYDVLPPAR
HACSPRTPRATGPACASPSRHGRRLPNGYYPAHGLARPRGPGSRKGLHEAYSETDDDDWC
NT seq 7743 nt   +upstreamnt  +downstreamnt
atgtggaagtcctcctgggtcctggaccccatgttctccccctacagctattatgatgcc
ctgcacaacggtggcttgggggcaccaggtccggcccccttgggcccgcccagcgtcccg
caggtcccacagtcccaccggatgagcagcatctgcgaagggccccctctgaagcggcgg
ggcggcctggtggaccaccgggatgtcatcttggcccaccaggcgcacaaaatccacagc
accccccaggccaggaggaaggaatgggaaatggcccgcttcggagacgagatgccggcc
cgctacgggggaggaggctccggggcagccgccggggtggtcgtgggcgccggaggcggg
cgaggagccgggggcagccggcagggcgggcagcccggggcgcaaaggatgtacaagcag
tcaatggcgcagagagcgcggaccatggccctctacaaccccatccccgtccgacagaac
tgcctcacggtcaaccggtctctgttcctcttcagcgaggacaacgtggtgagaaaatac
gccaaaaagatcaccgaatggcctccctttgaatatatgattttagccaccatcatagca
aactgcatcgtccttgccctggagcagcacctgcctgatgatgacaagacccccatgtct
gaacgattggatgacacagaaccgtacttcattggaattttttgtttcgaggctggcatt
aaaatcatcgcccttgggtttgccttccacaaaggctcttacttgaggaatggttggaat
gtgatggacttcgtcgtggtgctaacaggcatcttggcaacagtcgggacggagtttgac
ctgcggacactaagggcggttcgagtgctgcggcctctcaagctggtgtctgggatccca
agtttacaagtcgtcctgaagtcgatcatgaaggcgatgatccccttgctgcagatcggc
cttctcctattttttgcaatccttatttttgcaatcatagggttagaattttatatgggg
aaatttcataccacctgctttgaagaggggacagatgacattcagggtgagtctccagct
ccatgtgggacagaggaacccgcccgcacctgccccaatgggaccaaatgtcagccctac
tgggaagggcccaacaatgggatcactcagtttgacaacatcctgtttgcagtactgact
gttttccagtgcatcaccatggaagggtggactgacctcctctacaatagcaacgatgcc
tcagggaacacttggaactggttgtacttcatccctctcatcatcattggctcctttttt
atgctgaacctcgtgctgggtgtgctgtcaggagagtttgccaaagaaagggagcgggtg
gaaaaccggcgggcttttctaaagctgaggcggcagcaacagatcgaacgagagctcaat
gggtacatggagtggatctcaaaagcagaagaggtgatcctcgccgaggatgaaaccgac
ggggagcagaggcacccctttgatgttggagctctgcggagagccaccataaagaagagc
aagacagacctgctcaaccccgaggaggccgagggtcagcttgccgatatcgcctctgtg
ggctctccctttgcccgagccagcattaaaagtgccaagctggagaactcgacttttttt
cacaaaaaggagaggagggtgcgtttctacatccgccgcatggtcaaaactcaggccttc
tactggactgtgctcagtctggtagccctcaacacgctgtgtgttgctatcgttcactac
aaccagcccgagtggctctccgacttcctctactatgcagaattcattttcttaggactc
tttatgtccgaaatgtttataaaaatgtacgggcttgggacacggccttacttccactct
tccttcaactgctttgactgtggggtcatcatcggaagcatctttgaggtcatctgggcc
gtcataaaacctggcacatcctttggaatcagcgtgttacgagctctcaggttattgcgt
attttcaaagtcacaaagtactgggcatctctcaggaacctggtggtctctcttctcaac
tccatgaaatccatcatcagcctgctgttcctccttttcctgttcatcgtcgtctttgca
cttttgggaatgcagcttttcggtggccagtttaatttcgacgaagggactcctcctacc
aacttcgacacttttccagcagcaataatgacagtgtttcagattctgactggtgaggac
tggaacgaggtcatgtacgacggcatcaaatctcagggcggcgtgcagggtggcatggtg
ttctccatctacttcatcgtgctgacgctctttgggaactacaccctcctgaatgtgttc
ctggccattgcggtggataatttggccaatgctcaggagctcaccaaggacgaacaagaa
gaagaagaggcagccaaccagaaacttgccctccagaaagccaaggaggtggcagaagtg
agtcctctgtccgcggccagcatgtccatagctgtgaaggagcaacagaagaaccagaag
ccagccaagtccgtgtgggagcagcggacaagcgagatgcgcaagcagaacctgctggcc
agccgggaggccctctacaatgagatggacccggatgagcgctggaaggccacctacgcc
cggcacctgcggcccgacatgaagacccacctggaccggccgctggtggttgatccccag
gagaaccgcaacaacaacaccaacaagagccgggcggccgagcccacggtggaccagcgc
ctgggccagcagcgcgccgaggacttcctccggaaacaggcgcgctaccacgaccgggcc
cgggaccccagcggctccgtgggcttggacgcgcggcggccctgggccggcagccaggag
gccgagctgagccgggaggggccttatggccgtgagtcggaccaccacgcccgtgagggc
ggcctggagccgccgggcttctgggagggagaggccgagcgccccaaggccggcgacccc
caccggaggcacgcgcatcggccggggggcagccgggagagccgcagcgggtccccgcgc
accggagctgatggcgagccccgccggcaccgggcccatcgcaggccaggcgaggaggcc
ctggaggacaaggccgagcgcagatcccggcaccgcgagggctgccggccggcccgggga
ggcgagggcgagggccctgatggcggcgagcggaggcggcggcaccggcacggccccccg
gccacgtatgacatggagacacggagggaggacagggagcgcaggcaccggaggaggaaa
gacaaccagggctctggggtccctgtgtcgggccccaacctgtcgaccacccggccgatc
cagcaagatctgggccgccaagacccaccgctggctgaggacatcgacaacatgaagaac
aacaagctggccactgcggagtcggccagtcctcacgacagcctcggccactccggcctg
ccccagagcccagccaagatggggaacagcacccaccccggctccacgccggccccacct
gccacggccaccaatccccagaacaccgccagccgccgcgtgcccaacaacccggggaac
ccgtccaaccccggccccccgaagacccccgagaacagccttatcgtcaccaaccccagc
agtacccagaccaactcagctaagactgccaggaaacccgaccacaccacggtggacatc
cccccagcctgcccagcccccctcaaccacaccgttgtccaagtgaacaaaaacgccaac
ccagacccactgccaaaaaaggaggaaaagaagaaggaggaggaggaagacgaccccggg
gaagacggccccaagcccatgcccccctacagttccatgtttatcctctccacgaccaac
ccccttcgccgcctgtgccattacatcctgaacctgcgctactttgagatgtgcatcctc
atggtcatcgccatgagcagcatcgccctggcagccgaggaccccgtgcagcccaatgca
ccccggaacaacgtcctacgatattttgactacgttttcacaggtgtttttacctttgag
atggtaatcaagatgattgacctggggctcgtcctacaccagggtgcctacttccgtgat
ctctggaacattctcgacttcatagtggtcagtggggccttggtagcctttgccttcacg
agcagtacacgtggcaacagcaaaggaaaggacatcaacacgattaaatccctccgagtc
ctccgggtgctacgacctcttaaaaccatcaagcggttgccaaagctcaaggcggtgttt
gattgtgtggtgaattctctcaagaacgtcttcaacatcctcattgtctacatgctgttc
atgttcatctttgctgtggtggccgtgcagctcttcaaggggaagttcttccactgcact
gatgaatctaaggagtttgagaaggactgtcgtggcaagtacctcctctatgaaaagaac
gaggtgaaggcacgggaccgagagtggaggaagtatgagttccattatgacaacgtactg
tgggctctgctgaccctcttcactgtgtccacgggagaaggctggccgcaggtcctcaag
cactccgtagatgccaccttcgagaatcagggtcccagccccgggtaccgcatggagatg
tccatcttctacgtcgtctactttgtcgtgttccccttcttcttcgtcaatatctttgtg
gccttgatcatcatcaccttccaggagcagggggacaagatgatggaggaatacagcctg
gagaaaaatgagagggcctgcatcgacttcgccatcagcgccaaacctctgacccgacac
atgccccagaacaagcagagcttccagtaccgcatgtggcagtttgtggtgtctccgcct
ttcgagtacaccatcatggccatgatcgccctcaacaccattgtgctcatgatgaagttc
tatggggcctcgcttgcttatgaaaatgctctgagggtattcaacatcgtcttcacctcc
ctcttctctctggaatgtcttctgaaagtcatggcttttgggattctgaattatttccgt
gatgcctggaacatcttcgactttgtgactgttctgggcagcatcaccgacatcctcgtg
actgagtttgggaatccgaataacttcatcaacctgagcttcctccgcctcttccgagct
gctcgcctcatcaaactcctccgtcaaggttacaccatccgaattcttctctggaccttt
gtgcagtcattcaaggctctgccatatgtctgtctgctgattgccatgcttttcttcatc
tacgccatcatcgggatgcaggtgtttggcaacatcggtatcgacgtggaggacgaggac
agtgacgaggatgagttccagatcactgagcacaataacttccggacctttttccaggcc
ctcatgcttctcttccggagtgccaccggggaggcttggcacaacatcatgctttcctgc
ctcagtgggaagccatgtgataagaactctggcatcctgactcccgagtgtggcaatgag
tttgcttatttttacttcgtttccttcatcttcctctgctcgtttttgatgctgaacctc
tttgtcgccgttatcatggacaactttgagtacctcactcgagattcctccatcctgggg
ccccaccacctggatgagtacgtgcgtgtctgggccgagtacgaccccgcagcatggggc
cgcatgccttacccggacatgtatcagatgctgagacacatgtctccgcccctgggtctg
gggaagaagtgtccggccagagtggcttacaagagactactgcggatggatctgcccgtc
gctgatgacaacactgtccacttcaattctaccctcatggctctaatccgcactgccctg
gacatcaagattgccaagggaggggctgacaaacagcagatggacgccgagctacggaaa
gagatgatggccatctggcctaacctgtcccagaagacactggacctgctggtcacccct
cacaagtccacggacctgacagtggggaagatctatgcagccatgatgatcatggagtac
taccggcagagcaaggctaaaaagctacaggccatgcgagaggagcagaaccggacaccc
ctcatgttccagcgcatggagcccccatcaccaacgcaggagggggtgcctggccagaat
gcccttccctccacccagctggacccaggaggaggcctgatggctcacgaaggtggcatc
aaggagagcccttcctgggtgacccagcgagcccaagagatgttccagaagacgggcacg
tggagcccagagcgggggccccctaccgacatgcccaacagccagcccaactctcagtct
gtggagatgcgagagatgggccgggatggctactcagacagtgagcgctacctccccatg
gaaggccaggccagggccacctccatgccgcgcctccccgcggagaaccagaggagaagg
ggccggccacgtgggaataacctcagtaccatctcagataccagccccatgaagcgctca
gcctctgtgctgggccctaaggcccggcggctggatgactactccctagagagggtgccg
cctgaggagaaccagcggcaccaccagcggcgccgtgaccgcagccaccgcgcctccgag
cgctccctgggccgatacacagacgtggacacaggcttggggacagacctaagcatgacc
acccagtccggggacctgccatcgaaggagcgggaccaggagcggggccggcccaaggac
cggaagcaccggcagcaccatcaccaccaccaccaccaccaccccccaccccctgacaag
gagcgctatgcccaagagaggcaggaccaccgagcccggacccgggaccagcggtggtcc
cgctcccctagcgagggccgagagcacatggcacaccggcagggcagtagttccgtaagt
ggaagcccagccccctcaacatctggtaccagcactccgcggcggggccgccgccagctc
ccccagaccccctccactccccggccacatgtgtcctattcccccgtgatccgcaaagcc
ggcggaatggggcccccgcagcaacagcagcagccggtggcgcggcctggccgggcggcc
cccagcggcccgcggaggtacccaggccccgcagccgagcctttggccggggagcggccg
ccagggggacacggcagcagccgctcgcccgcaatggagcggcggggcccggcccggagc
gagtcccccagggcgtgccgccacagtggggcgcggtggccggcgtccgttgcgcacgcg
tccgaggggcccctgggctctcggcaccatggttactaccggggctccgactatgacgag
gccaatggcccgggcgtcagcggggacgacggaccctacgacgtgctgccccccgcgcga
cacgcctgttcgcccaggactccccgggccacgggcccggcctgcgcgtcgccttcccga
cacggccggcgactccccaacggctactaccccgcccacggactggccaggccccgcggg
ccgggctcccggaaaggcctgcacgaagcctacagcgagacggacgacgacgactggtgc
taa

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